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Piet Herdwijn (Piet Herdewijn)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 52

Top Venues

Nucleic acids research

Journal of medicinal chemistry

The Journal of organic chemistry

Chembiochem : a European journal of chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Hui Yang, Elena Eremeeva, Mikhail Abramov, Maarten Jacquemyn, Elisabetta Groaz, Dirk Daelemans, Piet Herdwijn
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic acids research 51 (4) (2023)
Hui Yang, Elena Eremeeva, Mikhail Abramov, Maarten Jacquemyn, Elisabetta Groaz, Dirk Daelemans, Piet Herdwijn
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic acids research (2023)
Hui Yang, Elena Eremeeva, Mikhail Abramov, Maarten Jacquemyn, Elisabetta Groaz, Dirk Daelemans, Piet Herdwijn
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic acids research 51 (4) (2023)
Peter Schofield, Alexander I Taylor, Jérôme Rihon, Cristian D Peña Martinez, Sacha Zinn, Charles-Alexandre Mattelaer, Jennifer Jackson, Gurpreet Dhaliwal, Guy Schepers, Piet Herdwijn, Eveline Lescrinier, Daniel Christ, Philipp Holliger
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif. Nucleic acids research (2023)
Aude Blanchard, Mikhail Abramov, Camille Hassan, Philippe Marlière, Piet Herdwijn, Valérie Pezo
A microbiological system for screening the interference of XNA monomers with DNA and RNA metabolism. RSC advances 13 (43) (2023)
Pradeep S Pallan, Terry P Lybrand, Eriks Rozners, Mikhail Abramov, Guy Schepers, Elena Eremeeva, Piet Herdwijn, Martin Egli
Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry (2023)
Hui Yang, Elena Eremeeva, Mikhail Abramov, Maarten Jacquemyn, Elisabetta Groaz, Dirk Daelemans, Piet Herdwijn
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic acids research 51 (4) (2023)
Mengmeng Wang, Kunyu Qu, Peipei Zhao, Xin Yin, Yiwei Meng, Piet Herdwijn, Chao Liu, Lixin Zhang, Xuekui Xia
Synthesis and anticancer evaluation of acetylated-lysine conjugated gemcitabine prodrugs. RSC medicinal chemistry 14 (8) (2023)
Hui Yang, Elena Eremeeva, Mikhail Abramov, Maarten Jacquemyn, Elisabetta Groaz, Dirk Daelemans, Piet Herdwijn
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids. Nucleic acids research 51 (4) (2023)
Hoai Nguyen, Mikhail Abramov, Jef Rozenski, Elena Eremeeva, Piet Herdwijn
In Vivo Assembly and Expression of DNA Containing Non-canonical Bases in the Yeast Saccharomyces cerevisiae. Chembiochem : a European journal of chemical biology 23 (11) (2022)
Lauriane Rietmeyer, Inès Li De La Sierra-Gallay, Guy Schepers, Delphine Dorchêne, Laura Iannazzo, Delphine Patin, Thierry Touzé, Herman van Tilbeurgh, Piet Herdwijn, Mélanie Ethève-Quelquejeu, Matthieu Fonvielle
Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis. Nucleic acids research 50 (20) (2022)
Mohammad Hajjar, Nicholas Chim, Chao Liu, Piet Herdwijn, John C Chaput
Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic acids research 50 (17) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Abhimanyu K Singh, Brent De Wijngaert, Marc Bijnens, Kris Uyttersprot, Hoai Nguyen, Sergio E Martinez, Dominique Schols, Piet Herdwijn, Christophe Pannecouque, Eddy Arnold, Kalyan Das
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine. Proceedings of the National Academy of Sciences of the United States of America 119 (30) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Shuai Tan, Elisabetta Groaz, Raj Kalkeri, Roger Ptak, Brent E Korba, Piet Herdwijn
Reshaping an Acyclic Nucleoside Phosphonate into a Selective Anti-hepatitis B Virus Compound. Journal of medicinal chemistry 65 (13) (2022)
Shuai Tan, Elisabetta Groaz, Mark N Prichard, Raj Kalkeri, Roger Ptak, Piet Herdwijn
Introduction of a cyano group at the 2-position of an (R,S)-3-hydroxy-2-(phosphonomethoxy)propyl (HPMP) derivative of thymine elicits selective anti-HBV activity. RSC medicinal chemistry 12 (5) (2021)
Valérie Pezo, Faten Jaziri, Pierre-Yves Bourguignon, Dominique Louis, Deborah Jacobs-Sera, Jef Rozenski, Sylvie Pochet, Piet Herdwijn, Graham F Hatfull, Pierre Alexandre Kaminski, Philippe Marlière
Noncanonical DNA polymerization by aminoadenine-based siphoviruses. Science (New York, N.Y.) 372 (6541) (2021)
Esau Medina, Eric J Yik, Piet Herdwijn, John C Chaput
Functional Comparison of Laboratory-Evolved XNA Polymerases for Synthetic Biology. ACS synthetic biology 10 (6) (2021)
Charles-Alexandre Mattelaer, Mohitosh Maiti, Laurent Smets, Munmun Maiti, Guy Schepers, Henri-Philippe Mattelaer, Helmut Rosemeyer, Piet Herdwijn, Eveline Lescrinier
Stable Hairpin Structures Formed by Xylose-Based Nucleic Acids. Chembiochem : a European journal of chemical biology 22 (9) (2021)
Camille Samson, Pierre Legrand, Mustafa Tekpinar, Jef Rozenski, Mikhail Abramov, Philipp Holliger, Vitor B Pinheiro, Piet Herdwijn, Marc Delarue
Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules 10 (12) (2020)
Min Luo, Shuo Wu, Raj Kalkeri, Roger G Ptak, Tianlun Zhou, Lieve Van Mellaert, Chuanmin Wang, Shrinivas G Dumbre, Timothy Block, Elisabetta Groaz, Steven De Jonghe, Yuhuan Li, Piet Herdwijn
Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine Prodrug. Journal of medicinal chemistry 63 (22) (2020)
Hui Yang, Elena Eremeeva, Mikhail Abramov, Piet Herdwijn
The Network of Replication, Transcription, and Reverse Transcription of a Synthetic Genetic Cassette. Angewandte Chemie (International ed. in English) 60 (8) (2020)
Weijie Gu, Sergio Martinez, Hoai Nguyen, Hongtao Xu, Piet Herdwijn, Steven De Jonghe, Kalyan Das
Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. Journal of medicinal chemistry 64 (1) (2020)
Shuntaro Takahashi, Piet Herdwijn, Naoki Sugimoto
Effect of Molecular Crowding on DNA Polymerase Reactions along Unnatural DNA Templates. Molecules (Basel, Switzerland) 25 (18) (2020)
Nikolaos Papastavrou, Omprakash Bande, Philippe Marlière, Elisabetta Groaz, Piet Herdwijn
Vitamin-guanosine monophosphate conjugates for in vitro transcription priming. Chemical communications (Cambridge, England) 56 (18) (2020)
Marie Flamme, Pascal Röthlisberger, Fabienne Levi-Acobas, Mohit Chawla, Romina Oliva, Luigi Cavallo, Gilles Gasser, Philippe Marlière, Piet Herdwijn, Marcel R Hollenstein
Enzymatic Formation of an Artificial Base Pair Using a Modified Purine Nucleoside Triphosphate. ACS chemical biology 15 (11) (2020)
Piotr Leonczak, Puneet Srivastava, Omprakash Bande, Guy Schepers, Eveline Lescrinier, Piet Herdwijn
N8-Glycosylated 8-Azapurine and Methylated Purine Nucleobases: Synthesis and Study of Base Pairing Properties. The Journal of organic chemistry 84 (21) (2019)
Fabienne Levi-Acobas, Pascal Röthlisberger, Ivo Sarac, Philippe Marlière, Piet Herdwijn, Marcel R Hollenstein
On the Enzymatic Formation of Metal Base Pairs with Thiolated and pKa -Perturbed Nucleotides. Chembiochem : a European journal of chemical biology 20 (24) (2019)
Min Luo, Elisabetta Groaz, Steven De Jonghe, Dominique Schols, Piet Herdwijn
Synthesis and Anti-HIV Activity of Guanine Modified Fluorinated Acyclic Nucleoside Phosphonate Derivatives. Chemistry & biodiversity 16 (2) (2019)
Jakub Modranka, Jiahong Li, Anastasia Parchina, Michiel Vanmeert, Shrinivas G Dumbre, Mayla Salman, Hannu Myllykallio, Hubert F Becker, Roeland Vanhoutte, Lia Margamuljana, Hoai Nguyen, Rania Abu El-Asrar, Jef Rozenski, Piet Herdwijn, Steven De Jonghe, Eveline Lescrinier
Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X. ChemMedChem 14 (6) (2019)
Min Luo, Elisabetta Groaz, Matheus Froeyen, Valérie Pezo, Faten Jaziri, Piotr Leonczak, Guy Schepers, Jef Rozenski, Philippe Marlière, Piet Herdwijn
Invading Escherichia coli Genetics with a Xenobiotic Nucleic Acid Carrying an Acyclic Phosphonate Backbone (ZNA). Journal of the American Chemical Society 141 (27) (2019)
John C Chaput, Piet Herdwijn
What Is XNA? Angewandte Chemie (International ed. in English) 58 (34) (2019)
Sven Verdonck, Szu-Yuan Pu, Fiona J Sorrell, Jon M Elkins, Matheus Froeyen, Ling-Jie Gao, Laura I Prugar, Danielle E Dorosky, Jennifer M Brannan, Rina Barouch-Bentov, Stefan Knapp, John M Dye, Piet Herdwijn, Shirit Einav, Steven De Jonghe
Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity. Journal of medicinal chemistry 62 (12) (2019)
Xiaochen Li, Shrinivas G Dumbre, Eveline Lescrinier, Elisabetta Groaz, Piet Herdwijn
Synthesis and Conformation of Pentopyranoside Nucleoside Phosphonates. The Journal of organic chemistry 84 (11) (2019)
Qingfeng Li, Leentje Persoons, Dirk Daelemans, Piet Herdwijn
Iron/Copper Co-Catalyzed Cross-Coupling Reaction for the Synthesis of 6-Substituted 7-Deazapurines and the Corresponding Nucleosides. The Journal of organic chemistry 85 (2) (2019)
Szu-Yuan Pu, Randy Wouters, Stanford Schor, Jef Rozenski, Rina Barouch-Bentov, Laura I Prugar, Cecilia M O'Brien, Jennifer M Brannan, John M Dye, Piet Herdwijn, Steven De Jonghe, Shirit Einav
Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity. Journal of medicinal chemistry 61 (14) (2018)
Peng Nie, Elisabetta Groaz, Steven De Jonghe, Eveline Lescrinier, Piet Herdwijn
Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization. Organic letters 20 (4) (2018)
Amit M Jabgunde, Faten Jaziri, Omprakash Bande, Matheus Froeyen, Mikhail Abramov, Hoai Nguyen, Guy Schepers, Eveline Lescrinier, Vitor B Pinheiro, Valérie Pezo, Philippe Marlière, Piet Herdwijn
Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (48) (2018)
James Reuberson, Helen Horsley, Richard J Franklin, Daniel Ford, Judi Neuss, Daniel Brookings, Qiuya Huang, Bart Vanderhoydonck, Ling-Jie Gao, Mi-Yeon Jang, Piet Herdwijn, Anant Ghawalkar, Farnaz Fallah-Arani, Adnan R Khan, Jamie Henshall, Mark Jairaj, Sarah Malcolm, Eleanor Ward, Lindsay Shuttleworth, Yuan Lin, Shengqiao Li, Thierry Louat, Mark Waer, Jean Herman, Andrew Payne, Tom Ceska, Carl Doyle, William R Pitt, Mark Calmiano, Martin Augustin, Stefan Steinbacher, Alfred Lammens, Rodger Allen
Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. Journal of medicinal chemistry 61 (15) (2018)
Chao Liu, Christopher Cozens, Faten Jaziri, Jef Rozenski, Amandine Maréchal, Shrinivas Dumbre, Valérie Pezo, Philippe Marlière, Vitor B Pinheiro, Elisabetta Groaz, Piet Herdwijn
Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers. Journal of the American Chemical Society 140 (21) (2018)
Swarup De, Amit M Jabgunde, Rahul S Patil, Steven De Jonghe, Leonid Beigelman, Piet Herdwijn
Synthesis of Protected Amino Hexitol Nucleosides as Building Blocks for Oligonucleotide Synthesis. The Journal of organic chemistry 83 (24) (2018)
Boris Bauwens, Jef Rozenski, Piet Herdwijn, Johan Robben
A Single Amino Acid Substitution in Therminator DNA Polymerase Increases Incorporation Efficiency of Deoxyxylonucleotides. Chembiochem : a European journal of chemical biology 19 (22) (2018)
Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdwijn, Philipp Holliger
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination. eLife 7 (2018)
Valérie Pezo, Camille Hassan, Dominique Louis, Bruno Sargueil, Piet Herdwijn, Philippe Marlière
Metabolic Recruitment and Directed Evolution of Nucleoside Triphosphate Uptake in Escherichia coli. ACS synthetic biology 7 (6) (2018)
Fabio da Paixao Soares, Elisabetta Groaz, Piet Herdwijn
Phosphorus Pentachloride Promoted gem-Dichlorination of 2'- and 3'-Deoxynucleosides. Molecules (Basel, Switzerland) 23 (6) (2018)
Min Luo, Elisabetta Groaz, Graciela Andrei, Robert Snoeck, Raj Kalkeri, Roger G Ptak, Tracy Hartman, Robert W Buckheit, Dominique Schols, Steven De Jonghe, Piet Herdwijn
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs. Journal of medicinal chemistry 60 (14) (2017)
Qingfeng Li, Eveline Lescrinier, Elisabetta Groaz, Leentje Persoons, Dirk Daelemans, Piet Herdwijn, Steven De Jonghe
Synthesis and Biological Evaluation of Pyrrolo[2,1-f][1,2,4]triazine C-Nucleosides with a Ribose, 2'-Deoxyribose, and 2',3'-Dideoxyribose Sugar Moiety. ChemMedChem 13 (1) (2017)
Swarup De, Steven De Jonghe, Piet Herdwijn
Synthesis of a 3'-Fluoro-3'-deoxytetrose Adenine Phosphonate. The Journal of organic chemistry 82 (18) (2017)
Amutha Ramaswamy, Daryna Smyrnova, Mathy Froeyen, Mohitosh Maiti, Piet Herdwijn, Arnout Ceulemans
Molecular Dynamics of Double Stranded Xylo-Nucleic Acid. Journal of chemical theory and computation 13 (10) (2017)
Rania Abu El Asrar, Lia Margamuljana, Mikhail Abramov, Omprakash Bande, Stefano Agnello, Miyeon Jang, Piet Herdwijn
Enzymatic Incorporation of Modified Purine Nucleotides in DNA. Chembiochem : a European journal of chemical biology 18 (24) (2017)

Piet Herdwijn.css-eqlu8i{font-size:small;padding-left:4px;} (Piet Herdewijn)

Publication Activity (10 Years)

Top Topics

Top Venues

Piet Herdwijn (Piet Herdewijn)