Philippe Lambin (P Lambin)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 51

Top Topics

Squamous Cell Carcinoma

Computed Tomography

Top Venues

Journal of personalized medicine

Diagnostics (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Loic Cuau, Pia Akl, Arthur Gautheron, Angèle Houmeau, Frédéric Chaput, Ala Yaromina, Ludwig Dubois, Philippe Lambin, Szilvia Karpati, Stéphane Parola, B Rezaeifar, Jean-Baptiste Langlois, Salim A Si-Mohamed, Bruno Montcel, Philippe Douek, Frederic Lerouge
Surface modification effect on contrast agent efficiency for X-ray based spectral photon-counting scanner/luminescence imaging: from fundamental study to in vivo proof of concept. Nanoscale (2024)
Ying Cong, Nick Devoogdt, Philippe Lambin, Ludwig J Dubois, Ala Yaromina
Promising Diagnostic and Therapeutic Approaches Based on VHHs for Cancer Management. Cancers 16 (2) (2024)
Ayoub Mokhtari, Roberto Casale, Zohaib Salahuddin, Zelda Paquier, Thomas Guiot, Henry C Woodruff, Philippe Lambin, Jean-Luc Van Laethem, Alain Hendlisz, Maria Antonietta Bali
Development of Clinical Radiomics-Based Models to Predict Survival Outcome in Pancreatic Ductal Adenocarcinoma: A Multicenter Retrospective Study. Diagnostics (Basel, Switzerland) 14 (7) (2024)
Ayoub Mokhtari, Roberto Casale, Zohaib Salahuddin, Zelda Paquier, Thomas Guiot, Henry C Woodruff, Philippe Lambin, Jean-Luc Van Laethem, Alain Hendlisz, Maria Antonietta Bali
Development of Clinical Radiomics-Based Models to Predict Survival Outcome in Pancreatic Ductal Adenocarcinoma: A Multicenter Retrospective Study. Diagnostics (Basel, Switzerland) 14 (7) (2024)
Loic Cuau, Pia Akl, Arthur Gautheron, Angèle Houmeau, Frédéric Chaput, Ala Yaromina, Ludwig Dubois, Philippe Lambin, Szilvia Karpati, Stéphane Parola, B Rezaeifar, Jean-Baptiste Langlois, Salim A Si-Mohamed, Bruno Montcel, Philippe Douek, Frederic Lerouge
Surface modification effect on contrast agent efficiency for X-ray based spectral photon-counting scanner/luminescence imaging: from fundamental study to in vivo proof of concept. Nanoscale 16 (6) (2024)
Ying Cong, Nick Devoogdt, Philippe Lambin, Ludwig J Dubois, Ala Yaromina
Promising Diagnostic and Therapeutic Approaches Based on VHHs for Cancer Management. Cancers 16 (2) (2024)
Ayoub Mokhtari, Roberto Casale, Zohaib Salahuddin, Zelda Paquier, Thomas Guiot, Henry C Woodruff, Philippe Lambin, Jean-Luc Van Laethem, Alain Hendlisz, Maria Antonietta Bali
Development of Clinical Radiomics-Based Models to Predict Survival Outcome in Pancreatic Ductal Adenocarcinoma: A Multicenter Retrospective Study. Diagnostics (Basel, Switzerland) 14 (7) (2024)
Loic Cuau, Pia Akl, Arthur Gautheron, Angèle Houmeau, Frédéric Chaput, Ala Yaromina, Ludwig Dubois, Philippe Lambin, Szilvia Karpati, Stéphane Parola, B Rezaeifar, Jean-Baptiste Langlois, Salim A Si-Mohamed, Bruno Montcel, Philippe Douek, Frederic Lerouge
Surface modification effect on contrast agent efficiency for X-ray based spectral photon-counting scanner/luminescence imaging: from fundamental study to in vivo proof of concept. Nanoscale 16 (6) (2024)
Zohaib Salahuddin, Yi Chen, Xian Zhong, Henry C Woodruff, Nastaran Mohammadian Rad, Shruti Atul Mali, Philippe Lambin
From Head and Neck Tumour and Lymph Node Segmentation to Survival Prediction on PET/CT: An End-to-End Framework Featuring Uncertainty, Fairness, and Multi-Region Multi-Modal Radiomics. Cancers 15 (7) (2023)
Rihab Hami, Sena Apeke, Pascal Redou, Laurent Gaubert, Ludwig J Dubois, Philippe Lambin, Dimitris Visvikis, Nicolas Boussion
Predicting the Tumour Response to Radiation by Modelling the Five Rs of Radiotherapy Using PET Images. Journal of imaging 9 (6) (2023)
Xian Zhong, Zohaib Salahuddin, Yi Chen, Henry C Woodruff, Haiyi Long, Jianyun Peng, Xiao-Yan Xie, Manxia Lin, Philippe Lambin
An Interpretable Radiomics Model Based on Two-Dimensional Shear Wave Elastography for Predicting Symptomatic Post-Hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma. Cancers 15 (21) (2023)
Y Widaatalla, Tom Wolswijk, Fieke Adan, Lisa M Hillen, Henry C Woodruff, Iva Halilaj, Abdalla Ibrahim, Philippe Lambin, Klara Mosterd
The application of artificial intelligence in the detection of basal cell carcinoma: A systematic review. Journal of the European Academy of Dermatology and Venereology : JEADV (2023)
Yanchao Zhang, Aleksandra M Kubiak, Tom S Bailey, Luuk Claessen, Philip Hittmeyer, Ludwig Dubois, Jan Theys, Philippe Lambin
Development of a CRISPR-Cas12a system for efficient genome engineering in clostridia. Microbiology spectrum (2023)
Rihab Hami, Sena Apeke, Pascal Redou, Laurent Gaubert, Ludwig J Dubois, Philippe Lambin, Dimitris Visvikis, Nicolas Boussion
Predicting the Tumour Response to Radiation by Modelling the Five Rs of Radiotherapy Using PET Images. Journal of imaging 9 (6) (2023)
Manon P L Beuque, Marc B I Lobbes, Yvonka van Wijk, Yousif Widaatalla, Sergey P Primakov, Michael Majer, Corinne Balleyguier, Henry C Woodruff, Philippe Lambin
Combining Deep Learning and Handcrafted Radiomics for Classification of Suspicious Lesions on Contrast-enhanced Mammograms. Radiology 307 (5) (2023)
Rihab Hami, Sena Apeke, Pascal Redou, Laurent Gaubert, Ludwig J Dubois, Philippe Lambin, Dimitris Visvikis, Nicolas Boussion
Predicting the Tumour Response to Radiation by Modelling the Five Rs of Radiotherapy Using PET Images. Journal of imaging 9 (6) (2023)
Turkey A Refaee, Zohaib Salahuddin, Yousif Widaatalla, Sergey Primakov, Henry C Woodruff, Roland Hustinx, Felix M Mottaghy, Abdalla Ibrahim, Philippe Lambin
CT Reconstruction Kernels and the Effect of Pre- and Post-Processing on the Reproducibility of Handcrafted Radiomic Features. Journal of personalized medicine 12 (4) (2022)
Erich P Huang, James P B O'Connor, Lisa Meier McShane, Maryellen L Giger, Philippe Lambin, Paul E Kinahan, Eliot L Siegel, Lalitha K Shankar
Criteria for the translation of radiomics into clinically useful tests. Nature reviews. Clinical oncology (2022)
Alexander M A van der Wiel, Lesley Schuitmaker, Ying Cong, Jan Theys, Arne Van Hoeck, Conchita Vens, Philippe Lambin, Ala Yaromina, Ludwig J Dubois
Homologous Recombination Deficiency Scar: Mutations and Beyond-Implications for Precision Oncology. Cancers 14 (17) (2022)
Abdalla Ibrahim, Bruno Barufaldi, Turkey A Refaee, Telmo M Silva Filho, Raymond J Acciavatti, Zohaib Salahuddin, Roland Hustinx, Felix Manuel Mottaghy, Andrew D A Maidment, Philippe Lambin
MaasPenn Radiomics Reproducibility Score: A Novel Quantitative Measure for Evaluating the Reproducibility of CT-Based Handcrafted Radiomic Features. Cancers 14 (7) (2022)
Iva Halilaj, Cary J G Oberije, Avishek Chatterjee, Yvonka van Wijk, Nastaran Mohammadian Rad, Prabash Galganebanduge, Elizaveta Lavrova, Sergey Primakov, Yousif Widaatalla, Anke Wind, Philippe Lambin
Open Source Repository and Online Calculator of Prediction Models for Diagnosis and Prognosis in Oncology. Biomedicines 10 (11) (2022)
Turkey A Refaee, Benjamin Bondue, Gaetan Van Simaeys, Guangyao Wu, Chenggong Yan, Henry C Woodruff, Serge Goldman, Philippe Lambin
A Handcrafted Radiomics-Based Model for the Diagnosis of Usual Interstitial Pneumonia in Patients with Idiopathic Pulmonary Fibrosis. Journal of personalized medicine 12 (3) (2022)
Sergey P Primakov, Abdalla Ibrahim, Janita E van Timmeren, Guangyao Wu, Simon A Keek, Manon P L Beuque, Renée W Y Granzier, Elizaveta Lavrova, Madeleine Scrivener, Sebastian Sanduleanu, Esma Kayan, Iva Halilaj, Anouk Lenaers, Jianlin Wu, René Monshouwer, Xavier Geets, Hester A Gietema, Lizza E L Hendriks, Olivier Morin, Arthur Jochems, Henry C Woodruff, Philippe Lambin
Automated detection and segmentation of non-small cell lung cancer computed tomography images. Nature communications 13 (1) (2022)
Akshayaa Vaidyanathan, Julien Guiot, Fadila Zerka, Flore Belmans, Ingrid Van Peufflik, Louis Deprez, Denis Danthine, Gregory Canivet, Philippe Lambin, Sean Walsh, Mariaelena Occhipinti, Paul Meunier, Wim Vos, Pierre Lovinfosse, Ralph T H Leijenaar
An externally validated fully automated deep learning algorithm to classify COVID-19 and other pneumonias on chest computed tomography. ERJ open research 8 (2) (2022)
Francesco Sforazzini, Patrick Salome, Mahmoud Moustafa, Cheng Zhou, Christian Schwager, Katrin Rein, Nina Bougatf, Andreas Kudak, Henry C Woodruff, Ludwig J Dubois, Philippe Lambin, Jürgen Debus, Amir Abdollahi, Maximilian Knoll
Deep Learning-based Automatic Lung Segmentation on Multiresolution CT Scans from Healthy and Fibrotic Lungs in Mice. Radiology. Artificial intelligence 4 (2) (2022)
Anne-Noëlle Frix, François Cousin, Turkey A Refaee, Fabio Bottari, Akshayaa Vaidyanathan, Colin Desir, Wim Vos, Sean Walsh, Mariaelena Occhipinti, Pierre Lovinfosse, Ralph T H Leijenaar, Roland Hustinx, Paul Meunier, Renaud Louis, Philippe Lambin, Julien Guiot
Radiomics in Lung Diseases Imaging: State-of-the-Art for Clinicians. Journal of personalized medicine 11 (7) (2021)
Jan C Peeken, Jan Neumann, Rebecca Asadpour, Yannik Leonhardt, Joao R Moreira, Daniel S Hippe, Olena Klymenko, Sarah C Foreman, Claudio E von Schacky, Matthew B Spraker, Stephanie K Schaub, Hendrik Dapper, Carolin Knebel, Nina A Mayr, Henry C Woodruff, Philippe Lambin, Matthew J Nyflot, Alexandra S Gersing, Stephanie E Combs
Prognostic Assessment in High-Grade Soft-Tissue Sarcoma Patients: A Comparison of Semantic Image Analysis and Radiomics. Cancers 13 (8) (2021)
Yvonka van Wijk, Bram Ramaekers, Ben G L Vanneste, Iva Halilaj, Cary J G Oberije, Avishek Chatterjee, Tom Marcelissen, Arthur Jochems, Henry C Woodruff, Philippe Lambin
Modeling-Based Decision Support System for Radical Prostatectomy Versus External Beam Radiotherapy for Prostate Cancer Incorporating an In Silico Clinical Trial and a Cost-Utility Study. Cancers 13 (11) (2021)
Chenggong Yan, Jie Lin, Haixia Li, Jun Xu, Tianjing Zhang, Hao Chen, Henry C Woodruff, Guangyao Wu, Siqi Zhang, Yikai Xu, Philippe Lambin
Cycle-Consistent Generative Adversarial Network: Effect on Radiation Dose Reduction and Image Quality Improvement in Ultralow-Dose CT for Evaluation of Pulmonary Tuberculosis. Korean journal of radiology 22 (6) (2021)
Fernando Navarro, Hendrik Dapper, Rebecca Asadpour, Carolin Knebel, Matthew B Spraker, Vincent Schwarze, Stephanie K Schaub, Nina A Mayr, Katja Specht, Henry C Woodruff, Philippe Lambin, Alexandra S Gersing, Matthew J Nyflot, Bjoern H Menze, Stephanie E Combs, Jan C Peeken
Development and External Validation of Deep-Learning-Based Tumor Grading Models in Soft-Tissue Sarcoma Patients Using MR Imaging. Cancers 13 (12) (2021)
Maikel Verduin, Sergey Primakov, Inge Compter, Henry C Woodruff, Sander M J van Kuijk, Bram L T Ramaekers, Maarten te Dorsthorst, Elles G M Revenich, Mark ter Laan, Sjoert A H Pegge, Frederick J A Meijer, Jan Beckervordersandforth, Ernst-Jan Maria Speel, Benno Kusters, Wendy W J de Leng, Monique M Anten, Martijn P G Broen, Linda Ackermans, Olaf E M G Schijns, Onno Teernstra, Koos Hovinga, Marc A Vooijs, Vivianne C G Tjan-Heijnen, Danielle B P Eekers, Alida A Postma, Philippe Lambin, Ann Hoeben
Prognostic and Predictive Value of Integrated Qualitative and Quantitative Magnetic Resonance Imaging Analysis in Glioblastoma. Cancers 13 (4) (2021)
Damiënne Marcus, Relinde I Y Lieverse, Carmen Klein, Amir Abdollahi, Philippe Lambin, Ludwig J Dubois, Ala Yaromina
Charged Particle and Conventional Radiotherapy: Current Implications as Partner for Immunotherapy. Cancers 13 (6) (2021)
Abdalla Ibrahim, Yousif Widaatalla, Turkey A Refaee, Sergey Primakov, Razvan L Miclea, Osman Öcal, Matthias Philipp Fabritius, Michael Ingrisch, Jens Ricke, Roland Hustinx, Felix M Mottaghy, Henry C Woodruff, Max Seidensticker, Philippe Lambin
Reproducibility of CT-Based Hepatocellular Carcinoma Radiomic Features across Different Contrast Imaging Phases: A Proof of Concept on SORAMIC Trial Data. Cancers 13 (18) (2021)
Abdalla Ibrahim, Turkey A Refaee, Sergey P Primakov, Bruno Barufaldi, Raymond J Acciavatti, Renée W Y Granzier, Roland Hustinx, Felix M Mottaghy, Henry C Woodruff, Joachim E Wildberger, Philippe Lambin, Andrew Douglas Arnold Maidment
The Effects of In-Plane Spatial Resolution on CT-Based Radiomic Features' Stability with and without ComBat Harmonization. Cancers 13 (8) (2021)
Abdalla Ibrahim, Turkey A Refaee, Sergey P Primakov, Bruno Barufaldi, Raymond J Acciavatti, Renée W Y Granzier, Roland Hustinx, Felix M Mottaghy, Henry C Woodruff, Joachim E Wildberger, Philippe Lambin, Andrew Douglas Arnold Maidment
Reply to Orlhac, F.; Buvat, I. Comment on "Ibrahim et al. The Effects of In-Plane Spatial Resolution on CT-Based Radiomic Features' Stability with and without ComBat Harmonization. Cancers 2021, 13, 1848". Cancers 13 (12) (2021)
Renée W Y Granzier, Abdalla Ibrahim, Sergey P Primakov, Sanaz Samiei, Thiemo J A van Nijnatten, Maaike de Boer, Esther M Heuts, Frans-Jan Hulsmans, Avishek Chatterjee, Philippe Lambin, Marc B I Lobbes, Henry C Woodruff, Marjolein L Smidt
MRI-Based Radiomics Analysis for the Pretreatment Prediction of Pathologic Complete Tumor Response to Neoadjuvant Systemic Therapy in Breast Cancer Patients: A Multicenter Study. Cancers 13 (10) (2021)
Olivier Morin, Martin Vallières, Steve Braunstein, Jorge Barrios Ginart, Taman Upadhaya, Henry C Woodruff, Alexander Zwanenburg, Avishek Chatterjee, Javier E Villanueva-Meyer, Gilmer Valdes, William Chen, Julian C Hong, Sue S Yom, Timothy D Solberg, Steffen Loeck, Jan Seuntjens, Catherine Park, Philippe Lambin
An artificial intelligence framework integrating longitudinal electronic health records with real-world data enables continuous pan-cancer prognostication. Nature cancer 2 (7) (2021)
Simon A Keek, Frederik W R Wesseling, Henry C Woodruff, Janita E van Timmeren, Irene H Nauta, Thomas K Hoffmann, Stefano Cavalieri, Giuseppina Calareso, Sergey Primakov, Ralph T H Leijenaar, Lisa Licitra, Marco Ravanelli, Kathrin Scheckenbach, Tito Poli, Davide Lanfranco, Marije R Vergeer, C René Leemans, Ruud H Brakenhoff, Frank J P Hoebers, Philippe Lambin
A Prospectively Validated Prognostic Model for Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck Based on Radiomics of Computed Tomography Images. Cancers 13 (13) (2021)
Emilie Anduran, Ludwig J Dubois, Philippe Lambin, Jean-Yves Winum
Hypoxia-activated prodrug derivatives of anti-cancer drugs: a patent review 2006 - 2021. Expert opinion on therapeutic patents (2021)
Shruti Atul Mali, Abdalla Ibrahim, Henry C Woodruff, Vincent Andrearczyk, Henning Muller, Sergey Primakov, Zohaib Salahuddin, Avishek Chatterjee, Philippe Lambin
Making Radiomics More Reproducible across Scanner and Imaging Protocol Variations: A Review of Harmonization Methods. Journal of personalized medicine 11 (9) (2021)
Avishek Chatterjee, Cosimo Nardi, Cary Oberije, Philippe Lambin
Knowledge Graphs for COVID-19: An Exploratory Review of the Current Landscape. Journal of personalized medicine 11 (4) (2021)
Ricardo Otazo, Philippe Lambin, Jean-Philippe Pignol, Mark E Ladd, Heinz-Peter Schlemmer, Michael Baumann, Hedvig Hricak
MRI-guided Radiation Therapy: An Emerging Paradigm in Adaptive Radiation Oncology. Radiology 298 (2) (2020)
Alexander Zwanenburg, Martin Vallières, Mahmoud A Abdalah, Hugo J W L Aerts, Vincent Andrearczyk, Aditya P Apte, Saeed Ashrafinia, Spyridon Bakas, Roelof J Beukinga, Ronald Boellaard, Marta Bogowicz, Luca Boldrini, Irène Buvat, Gary J R Cook, Christos Davatzikos, Adrien Depeursinge, Marie-Charlotte Desseroit, Nicola Dinapoli, Cuong Viet Dinh, Sebastian Echegaray, Issam El Naqa, Andriy Y Fedorov, Roberto Gatta, Robert James Gillies, Vicky J Goh, Michael Götz, Matthias Guckenberger, Sung Min Ha, Mathieu Hatt, Fabian Isensee, Philippe Lambin, Stefan Leger, Ralph T H Leijenaar, Jacopo Lenkowicz, Fiona Lippert, Are Losnegård, Klaus H Maier-Hein, Olivier Morin, Henning Muller, Sandy Napel, Christophe Nioche, Fanny Orlhac, Sarthak Pati, Elisabeth A G Pfaehler, Xinchi Hou, Arvind U K Rao, Jonas Scherer, Muhammad Musib Siddique, Nanna M Sijtsema, Jairo Socarras Fernandez, Emiliano Spezi, Roel J H M Steenbakkers, Stephanie Tanadini-Lang, Daniela Thorwarth, Esther G C Troost, Taman Upadhaya, Vincenzo Valentini, Lisanne V van Dijk, Joost J M van Griethuysen, Floris H P van Velden, Philip Whybra, Christian Richter, Steffen Loeck
The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping. Radiology 295 (2) (2020)
Alice C O'Farrell, Monika A Jarzabek, Andreas U Lindner, Steven Carberry, Emer Conroy, Ian S Miller, Kate Connor, Liam Shiels, Eugenia R Zanella, Federico Lucantoni, Adam Lafferty, Kieron White, Mariangela Meyer Meyer Villamandos, Patrick Dicker, William M Gallagher, Simon A Keek, Sebastian Sanduleanu, Philippe Lambin, Henry C Woodruff, Andrea Bertotti, Livio Trusolino, Annette T Byrne, Jochen H M Prehn
Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models. Cancers 12 (10) (2020)
Guangyao Wu, Henry C Woodruff, Jing Shen, Turkey A Refaee, Sebastian Sanduleanu, Abdalla Ibrahim, Ralph T H Leijenaar, Rui Wang, Jingtong Xiong, Jie Bian, Jianlin Wu, Philippe Lambin
Diagnosis of Invasive Lung Adenocarcinoma Based on Chest CT Radiomic Features of Part-Solid Pulmonary Nodules: A Multicenter Study. Radiology 297 (2) (2020)
Sebastian Sanduleanu, Alexander M A van der Wiel, Relinde I Y Lieverse, Damiënne Marcus, Abdalla Ibrahim, Sergey Primakov, Guangyao Wu, Jan Theys, Ala Yaromina, Ludwig J Dubois, Philippe Lambin
Hypoxia PET Imaging with [18F]-HX4-A Promising Next-Generation Tracer. Cancers 12 (5) (2020)
Guangyao Wu, Henry C Woodruff, Avishek Chatterjee, Philippe Lambin
Reply to "COVID-19 prediction models should adhere to methodological and reporting standards". The European respiratory journal 56 (3) (2020)
Sara J Hamis, Mohammad Kohandel, Ludwig J Dubois, Ala Yaromina, Philippe Lambin, Gibin G Powathil
Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape. PLoS computational biology 16 (8) (2020)
Guangyao Wu, Pei Yang, Yuanliang Xie, Henry C Woodruff, Xiangang Rao, Julien Guiot, Anne-Noelle Frix, Renaud Louis, Michel Moutschen, Jiawei Li, Jing Li, Chenggong Yan, Dan Du, Shengchao Zhao, Yi Ding, Bin Liu, Wenwu Sun, Fabrizio Albarello, Alessandra D'Abramo, Vincenzo Schininà, Emanuele Nicastri, Mariaelena Occhipinti, Giovanni Barisione, Iva Halilaj, Pierre Lovinfosse, Xiang Wang, Jianlin Wu, Philippe Lambin
Development of a clinical decision support system for severity risk prediction and triage of COVID-19 patients at hospital admission: an international multicentre study. The European respiratory journal 56 (2) (2020)
Julien Guiot, Akshayaa Vaidyanathan, Louis Deprez, Fadila Zerka, Denis Danthine, Anne-Noëlle Frix, Marie Thys, Monique Henket, Gregory Canivet, Stephane Mathieu, Evanthia Eftaxia, Philippe Lambin, Nathan Tsoutzidis, Benjamin Miraglio, Sean Walsh, Michel Moutschen, Renaud Louis, Paul Meunier, Wim Vos, Ralph T H Leijenaar, Pierre Lovinfosse
Development and Validation of an Automated Radiomic CT Signature for Detecting COVID-19. Diagnostics (Basel, Switzerland) 11 (1) (2020)
Inge Compter, Danielle B P Eekers, Ann Hoeben, Kasper M A Rouschop, Bart Reymen, Linda Ackermans, Jan Beckervordersantforth, Noel J C Bauer, Monique M Anten, Pieter Wesseling, Alida A Postma, Dirk De Ruysscher, Philippe Lambin
Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial. Autophagy 17 (9) (2020)