Philippe N Bolduc

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 15

Top Topics

Reduced Graphene Oxide

Severe Traumatic Brain Injury

Top Venues

Journal of medicinal chemistry

Organic letters

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Gabriele Laudadio, Philipp Neigenfind, Rajesh Chebolu, Vanna D Blasczak, Shambabu Joseph Maddirala, Maximilian D Palkowitz, Philippe N Bolduc, Michael C Nicastri, Ravi Kumar Puthukanoori, Bheema Rao Paraselli, Phil S Baran
Synthesis of Unnatural Amino Acids via Ni/Ag Electrocatalytic Cross-Coupling. Organic letters 26 (11) (2024)
Philippe N Bolduc, Magnus Pfaffenbach, Ryan Evans, Zhili Xin, Kate L Henry, Fang Gao, Terry Fang, John Silbereis, Jorge Vera Rebollar, Pei Li, Jayanth V Chodaparambil, Claire Metrick, Emily A Peterson
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors. ACS medicinal chemistry letters 15 (5) (2024)
Ryan Evans, Philippe N Bolduc, Magnus Pfaffenbach, Fang Gao, Tricia May-Dracka, Terry Fang, Brian T Hopkins, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Claire Metrick, Ashley Nelson, Patrick Trapa, Ankur Thomas, Linda Burkly, Emily A Peterson
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)- N -(6-methylpyrazolo[1,5- a ]pyrimidin-3-yl)imidazo[1,2- a ]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke. Journal of medicinal chemistry 67 (6) (2024)
Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin, Fang Gao, Ryan Evans, Terry Fang, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Steven Mathieu, Claire Metrick, Jorge A Vera Rebollar, Rong-Fang Gu, Christie-Ann Mccarl, John Silbereis, Emily A Peterson
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation. Journal of medicinal chemistry 67 (10) (2024)
Xu-Cheng Gan, Benxiang Zhang, Nathan Dao, Cheng Bi, Maithili Pokle, Liyan Kan, Michael R Collins, Chet C Tyrol, Philippe N Bolduc, Michael C Nicastri, Yu Kawamata, Phil S Baran, Ryan A Shenvi
Carbon quaternization of redox active esters and olefins by decarboxylative coupling. Science (New York, N.Y.) 384 (6691) (2024)
Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin, Fang Gao, Ryan Evans, Terry Fang, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Steven Mathieu, Claire Metrick, Jorge A Vera Rebollar, Rong-Fang Gu, Christie-Ann Mccarl, John Silbereis, Emily A Peterson
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation. Journal of medicinal chemistry (2024)
Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin, Fang Gao, Ryan Evans, Terry Fang, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Steven Mathieu, Claire Metrick, Jorge A Vera Rebollar, Rong-Fang Gu, Christie-Ann Mccarl, John Silbereis, Emily A Peterson
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation. Journal of medicinal chemistry 67 (10) (2024)
Gabriele Laudadio, Philipp Neigenfind, Rajesh Chebolu, Vanna D Blasczak, Shambabu Joseph Maddirala, Maximilian D Palkowitz, Philippe N Bolduc, Michael C Nicastri, Ravi Kumar Puthukanoori, Bheema Rao Paraselli, Phil S Baran
Synthesis of Unnatural Amino Acids via Ni/Ag Electrocatalytic Cross-Coupling. Organic letters 26 (11) (2024)
Ryan Evans, Philippe N Bolduc, Magnus Pfaffenbach, Fang Gao, Tricia May-Dracka, Terry Fang, Brian T Hopkins, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Claire Metrick, Ashley Nelson, Patrick Trapa, Ankur Thomas, Linda Burkly, Emily A Peterson
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)- N -(6-methylpyrazolo[1,5- a ]pyrimidin-3-yl)imidazo[1,2- a ]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke. Journal of medicinal chemistry (2024)
Philippe N Bolduc, Magnus Pfaffenbach, Ryan Evans, Zhili Xin, Kate L Henry, Fang Gao, Terry Fang, John Silbereis, Jorge Vera Rebollar, Pei Li, Jayanth V Chodaparambil, Claire Metrick, Emily A Peterson
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors. ACS medicinal chemistry letters 15 (5) (2024)
Gabriele Laudadio, Philipp Neigenfind, Rajesh Chebolu, Vanna D Blasczak, Shambabu Joseph Maddirala, Maximilian D Palkowitz, Philippe N Bolduc, Michael C Nicastri, Ravi Kumar Puthukanoori, Bheema Rao Paraselli, Phil S Baran
Synthesis of Unnatural Amino Acids via Ni/Ag Electrocatalytic Cross-Coupling. Organic letters (2024)
Ryan Evans, Philippe N Bolduc, Magnus Pfaffenbach, Fang Gao, Tricia May-Dracka, Terry Fang, Brian T Hopkins, Jayanth V Chodaparambil, Kate L Henry, Pei Li, Claire Metrick, Ashley Nelson, Patrick Trapa, Ankur Thomas, Linda Burkly, Emily A Peterson
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)- N -(6-methylpyrazolo[1,5- a ]pyrimidin-3-yl)imidazo[1,2- a ]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke. Journal of medicinal chemistry 67 (6) (2024)
Benxiang Zhang, Jiayan He, Yang Gao, Laura Levy, Martins S Oderinde, Maximilian D Palkowitz, T G Murali Dhar, Michael D Mandler, Michael R Collins, Daniel C Schmitt, Philippe N Bolduc, TeYu Chen, Sebastian Clementson, Nadia Nasser Petersen, Gabriele Laudadio, Cheng Bi, Yu Kawamata, Phil S Baran
Complex molecule synthesis by electrocatalytic decarboxylative cross-coupling. Nature (2023)
Philippe N Bolduc, Magnus Pfaffenbach, Vanna D Blasczak, Steven R Mathieu, Emily A Peterson
Synthesis of N-Substituted 3-Amino-2-pyridones. Organic letters 24 (33) (2022)
Maximilian D Palkowitz, Gabriele Laudadio, Simon Kolb, Jin Choi, Martins S Oderinde, Tamara El-Hayek Ewing, Philippe N Bolduc, TeYu Chen, Hao Zhang, Peter T W Cheng, Benxiang Zhang, Michael D Mandler, Vanna D Blasczak, Jeremy M Richter, Michael R Collins, Ryan L Schioldager, Martin Bravo, T G Murali Dhar, Benjamin Vokits, Yeheng Zhu, Pierre-Georges Echeverria, Michael A Poss, Scott A Shaw, Sebastian Clementson, Nadia Nasser Petersen, Pavel K Mykhailiuk, Phil S Baran
Overcoming Limitations in Decarboxylative Arylation via Ag-Ni Electrocatalysis. Journal of the American Chemical Society 144 (38) (2022)