Ralf Kühn

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Topics

Extracellular Matrix

Dendritic Cells

Top Venues

Nature immunology

Nature communications

Life science alliance

This page only lists publications with an associated author ORCID identifier.

Publications

Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda Anna Michelle Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C Miller, Annett Böddrich, Amin Polzin, Felix Distelmaier, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E Wanker, Josef Priller, Jakob J Metzger, Alessandro Prigione
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nature communications 15 (1) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology (2024)
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda Anna Michelle Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C Miller, Annett Böddrich, Amin Polzin, Felix Distelmaier, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E Wanker, Josef Priller, Jakob J Metzger, Alessandro Prigione
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nature communications 15 (1) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda Anna Michelle Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C Miller, Annett Böddrich, Amin Polzin, Felix Distelmaier, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E Wanker, Josef Priller, Jakob J Metzger, Alessandro Prigione
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nature communications 15 (1) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Anja Schütz, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
Author Correction: IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2024)
Seren Sevim-Wunderlich, Tu Dang, Jana Rossius, Frank Schnuetgen, Ralf Kühn
A Mouse Model of X-Linked Chronic Granulomatous Disease for the Development of CRISPR/Cas9 Gene Therapy. Genes 15 (6) (2024)
Seren Sevim-Wunderlich, Tu Dang, Jana Rossius, Frank Schnuetgen, Ralf Kühn
A Mouse Model of X-Linked Chronic Granulomatous Disease for the Development of CRISPR/Cas9 Gene Therapy. Genes 15 (6) (2024)
Tobias M Brunner, Sebastian Serve, Anna-Friederike Marx, Jelizaveta Fadejeva, Philippe Saikali, Maria Dzamukova, Nayar Durán-Hernández, Christoph Kommer, Frederik R Heinrich, Pawel Durek, Gitta Anne Heinz, Thomas Höfer, Mir-Farzin Mashreghi, Ralf Kühn, Daniel D Pinschewer, Max Löhning
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses. Nature immunology 25 (2) (2024)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology 24 (3) (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
Publisher Correction: IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology 24 (3) (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
Publisher Correction: IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology 24 (3) (2023)
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weissert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nature immunology (2023)
Ngoc Tung Tran, Eric Danner, Xun Li, Robin Graf, Mikhail Y Lebedin, Kathrin de la Rosa, Ralf Kühn, Klaus Rajewsky, Van Trung Chu
Precise CRISPR-Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells. Science advances 8 (22) (2022)
Andreas Franz, A Ioana Weber, Florian Heyd, Nicole Dimos, Alexander Stumpf, Yanlong Ji, Laura Moreno-Velasquez, Anne Voigt, Frederic Schulz, Alexander Neumann, Benno Kuropka, Ralf Kühn, Henning Urlaub, Dietmar Schmitz, Markus C Wahl, Florian Heyd
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Life science alliance 6 (3) (2022)
Andreas Franz, A Ioana Weber, Florian Heyd, Nicole Dimos, Alexander Stumpf, Yanlong Ji, Laura Moreno-Velasquez, Anne Voigt, Frederic Schulz, Alexander Neumann, Benno Kuropka, Ralf Kühn, Henning Urlaub, Dietmar Schmitz, Markus C Wahl, Florian Heyd
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Life science alliance 6 (3) (2022)
Andreas Franz, A Ioana Weber, Florian Heyd, Nicole Dimos, Alexander Stumpf, Yanlong Ji, Laura Moreno-Velasquez, Anne Voigt, Frederic Schulz, Alexander Neumann, Benno Kuropka, Ralf Kühn, Henning Urlaub, Dietmar Schmitz, Markus C Wahl, Florian Heyd
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Life science alliance 6 (3) (2022)
Ulrike Pfohl, Jürgen Loskutov, Sanum Bashir, Ralf Kühn, Patrick Herter, Markus Templin, Soulafa Mamlouk, Sergei Belanov, Michael Linnebacher, Florian Bürtin, Marcus Vetter, Christoph Reinhard, Lena Wedeken, Christian R A Regenbrecht
A RAS-Independent Biomarker Panel to Reliably Predict Response to MEK Inhibition in Colorectal Cancer. Cancers 14 (13) (2022)
Parivash Nouri, Anja Zimmer, Stefanie Brüggemann, Robin Friedrich, Ralf Kühn, Nilima Prakash
Generation of a NES -mScarlet Red Fluorescent Reporter Human iPSC Line for Live Cell Imaging and Flow Cytometric Analysis and Sorting Using CRISPR-Cas9-Mediated Gene Editing. Cells 11 (2) (2022)
Maria Dzamukova, Tobias M Brunner, Jadwiga Miotla-Zarebska, Frederik R Heinrich, Thorsten Schinke, Mir-Farzin Mashreghi, Anjali P Kusumbe, Ralf Kühn, Thorsten Schinke, Tonia L Vincent, Max Löhning
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth. Nature communications 13 (1) (2022)
Chiara Anania, Rafael D Acemel, Johanna Jedamzick, Adriano Bolondi, Giulia Cova, Norbert Brieske, Ralf Kühn, Lars Wittler, Francisca M Real, Darío G Lupiáñez
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation. Nature genetics 54 (7) (2022)
Andreas Franz, A Ioana Weber, Florian Heyd, Nicole Dimos, Alexander Stumpf, Yanlong Ji, Laura Moreno-Velasquez, Anne Voigt, Frederic Schulz, Alexander Neumann, Benno Kuropka, Ralf Kühn, Henning Urlaub, Dietmar Schmitz, Markus C Wahl, Florian Heyd
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP. Life science alliance 6 (3) (2022)
Florian Krause, Kourosh Mohebian, Manuel Delpero, Deike Hesse, Ralf Kühn, Danny Arends, Gudrun A Brockmann
A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse. Mammalian genome : official journal of the International Mammalian Genome Society 33 (3) (2021)
Ralf Kühn
Genome engineering in rodents - status quo and perspectives. Laboratory animals (2021)
Gizem Inak, Agnieszka Rybak-Wolf, Pawel Lisowski, Tancredi M Pentimalli, René Jüttner, Petar Glažar, Karan Uppal, Emanuela Bottani, Dario Brunetti, Christopher Secker, Annika Zink, David Meierhofer, Marie-Thérèse Henke, Monishita Dey, Ummi Ciptasari, Barbara Mlody, Tobias Hahn, Maria Berruezo-Llacuna, Nikos Karaiskos, Michela Di Virgilio, Johannes Adalbert Mayr, Saskia B Wortmann, Josef Priller, Michael Gotthardt, Dean P Jones, Ertan Mayatepek, Werner Stenzel, Sebastian Diecke, Ralf Kühn, Erich E Wanker, Nikolaus Rajewsky, Markus Schuelke, Alessandro Prigione
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nature communications 12 (1) (2021)
Marie-Christine Birling, Atsushi Yoshiki, David J Adams, Shinya Ayabe, Arthur L Beaudet, Joanna Bottomley, Allan Bradley, Steve D M Brown, Antje Bürger, Wendy Bushell, Francesco Chiani, Hsian-Jean Genie Chin, Skevoulla Christou, Gemma F Codner, Francesco J DeMayo, Mary E Dickinson, Brendan Doe, Leah Rae Donahue, Martin D Fray, Alessia Gambadoro, Xiang Gao, Marina Gertsenstein, Alba Gomez-Segura, Leslie O Goodwin, Jason D Heaney, Yann Hérault, Martin Hrabě de Angelis, Si-Tse Jiang, Monica J Justice, Petr Kasparek, Ruairidh E King, Ralf Kühn, Ho Lee, Young-Jae Lee, Zhiwei Liu, Kevin C Kent Lloyd, Isabel Lorenzo, Ann-Marie Mallon, Colin McKerlie, Terrence F Meehan, Violeta Munoz Fuentes, Stuart Newman, Lauryl M J Nutter, Goo Taeg Oh, Guillaume Pavlovic, Ramiro Ramirez-Solis, Barry Rosen, Edward J Ryder, Luis A Santos, Joel A Schick, John R Seavitt, Radislav Sedlacek, Claudia Seisenberger, Je Kyung Seong, William C Skarnes, Tania Sorg, Karen P Steel, Masaru Tamura, Glauco P Tocchini-Valentini, Chi-Kuang Leo Wang, Hannah Wardle-Jones, Marie Wattenhofer-Donzé, Sara Wells, Michael V Wiles, Brandon J Willis, Joshua A Wood, Wolfgang Wurst, Ying Xu, null null, Lydia Teboul, Stephen A Murray
A resource of targeted mutant mouse lines for 5,061 genes. Nature genetics 53 (4) (2021)
Sanum Bashir, Tu Dang, Jana Rossius, Johanna Wolf, Ralf Kühn
Enhancement of CRISPR-Cas9 induced precise gene editing by targeting histone H2A-K15 ubiquitination. BMC biotechnology 20 (1) (2020)
Natalja Funk, Marita Munz, Thomas Ott, Kathrin Brockmann, Andrea Wenninger-Weinzierl, Ralf Kühn, Daniela Vogt-Weisenhorn, Florian Giesert, Wolfgang Wurst, Thomas Gasser, Saskia Biskup
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4. Scientific reports 9 (1) (2019)
Stefanie Sperling, Petra Fiedler, Markus Lechner, Anna Pollithy, Stefanie Ehrenberg, Ana-Iris Schiefer, Lukas Kenner, Annette Feuchtinger, Ralf Kühn, Gene Swinerd, Marc Schmidt Supprian, Lothar J Strobl, Ursula Zimber-Strobl
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells. Blood 133 (24) (2019)
Caroline Fecher, Laura Trovò, Stephan A Müller, Nicolas Snaidero, Jennifer Wettmarshausen, Sylvia Heink, Oskar Ortiz, Ingrid Wagner, Ralf Kühn, Jana Hartmann, Rosa Maria Karl, Arthur Konnerth, Thomas Korn, Wolfgang Wurst, Doron Merkler, Stefan F Lichtenthaler, Fabiana Perocchi, Thomas Misgeld
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Nature neuroscience 22 (10) (2019)
Eric Danner, Sanum Bashir, Saniye Yumlu, Wolfgang Wurst, Benedikt Wefers, Ralf Kühn
Control of gene editing by manipulation of DNA repair mechanisms. Mammalian genome : official journal of the International Mammalian Genome Society 28 (7-8) (2017)
Monika Piwecka, Petar Glažar, Luis Rodrigo Hernandez-Miranda, Sebastian Memczak, Susanne A Wolf, Agnieszka Rybak-Wolf, Andrei Filipchyk, Filippos Klironomos, Cledi Alicia Cerda Jara, Pascal Fenske, Thorsten Trimbuch, Vera Zywitza, Mireya Plass, Luisa Schreyer, Salah Ayoub, Christine Kocks, Ralf Kühn, Christian Rosenmund, Carmen Birchmeier, Nikolaus Rajewsky
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science (New York, N.Y.) 357 (6357) (2017)