Doron Merkler

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Traumatic Brain Injury

Cerebrospinal Fluid

Regulatory T Cells

Top Venues

The Journal of experimental medicine

Nature communications

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Regina Rose Reimann, Dorothee Gramatzki, Andrea Bink, Juergen Hench, Stephan Frank, Martina Haberecker, Hortobágyi Tibor, Kristof Egervari, Doron Merkler, Kenneth D Aldape, Michael Weller
Long survival in a patient with fumarate hydratase mutation-associated glioma. Journal of neuropathology and experimental neurology (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Iris Winkler, Jan Broder Engler, Vanessa Vieira, Simone Bauer, Yi-Hsiang Liu, Giovanni Di Liberto, Katarzyna M Grochowska, Ingrid Wagner, Jasmina Bier, Lukas Can Bal, Nicola Rothammer, Nina Kursawe, Kristof Egervari, Benjamin Schattling, Gabriela Salinas, Michael R Kreutz, Yi-Shuian Huang, Ole Pless, Doron Merkler, Nicolaus Kröger
MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration. Science advances 9 (47) (2023)
Tristan Born, Paola Vassallo, Déla Golshayan, Giovanni Di Liberto, Jean-Philippe Brouland, Kristof Egervari, Doron Merkler, Renaud A Du Pasquier, Raphael Bernard-Valnet
Bridging the Gap: Immunotherapy in Progressive Multifocal Leukoencephalopathy: A New Hope? Neurology (2023)
Sidar Aydin, Javier Pareja, Vivianne M Schallenberg, Armelle Klopstein, Thomas Gruber, Nicolas Page, Elisa Bouillet, Nicolas Blanchard, Roland Liblau, Jakob Körbelin, Markus Schwaninger, Aaron J Johnson, Mirjam Schenk, Urban Deutsch, Doron Merkler, Britta Engelhardt
Antigen recognition detains CD8 + T cells at the blood-brain barrier and contributes to its breakdown. Nature communications 14 (1) (2023)
Nicola Rothammer, Marcel Seungsu Woo, Simone Bauer, Lars Binkle, Giovanni Di Liberto, Kristof Egervari, Ingrid Wagner, Undine Haferkamp, Ole Pless, Doron Merkler, Jan Broder Engler, Nicolaus Kröger
G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis. Science advances 8 (31) (2022)
Juliane K Lohmeyer, Toshihito Hirai, Mustafa Turkoz, Stephane Buhler, Teresa Lopes Ramos, Natalie Stickel, Jeanette Baker, Astrid Melotti, Ingrid Wagner, Amandine Pradier, Sisi Wang, Xuhuai Ji, Simone Becattini, Jean Villard, Doron Merkler, Yves Chalandon, Robert S Negrin, Federico Simonetta
Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of GvHD. Blood (2022)
David Frieser, Aurora Pignata, Leila Khajavi, Danielle Shlesinger, Carmen Gonzalez-Fierro, Xuan-Hung Nguyen, Alexander Yermanos, Doron Merkler, Romana Höftberger, Virginie Desestret, Katharina M Mair, Jan Bauer, Frederick Masson, Roland S Liblau
Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons. Science translational medicine 14 (640) (2022)
Laure Garnier, Robert Pick, Julien Montorfani, Mengzhu Sun, Dale Brighouse, Nicolas Liaudet, Thomas Kammertoens, Thomas Blankenstein, Nicolas Page, Jeremiah Bernier-Latamani, Ngoc Lan Tran, Tatiana V Petrova, Doron Merkler, Christoph Scheiermann, Stephanie Hugues
IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis. Science advances 8 (23) (2022)
Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler
Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV. Brain : a journal of neurology 145 (8) (2022)
Juliane K Lohmeyer, Toshihito Hirai, Mustafa Turkoz, Stephane Buhler, Teresa Lopes Ramos, Natalie Stickel, Jeanette Baker, Astrid Melotti, Ingrid Wagner, Amandine Pradier, Sisi Wang, Xuhuai Ji, Simone Becattini, Jean Villard, Doron Merkler, Yves Chalandon, Robert S Negrin, Federico Simonetta
Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of GvHD. Blood (2022)
Laura Empl, Alexandra Chovsepian, Maryam Chahin, Wing Yin Vanessa Kan, Julie Fourneau, Valerie Van Steenbergen, Sanofer Weidinger, Maite Marcantoni, Alexander Ghanem, Peter Bradley, Karl Klaus Conzelmann, Ruiyao Cai, Alireza Ghasemigharagoz, Ali Ertürk, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Sabine Liebscher, Florence M Bareyre
Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury. Nature communications 13 (1) (2022)
Ilena Vincenti, Nicolas Page, Karin Steinbach, Alexander Yermanos, Sylvain Lemeille, Nicolas Nunez, Mario Kreutzfeldt, Bogna Klimek, Giovanni Di Liberto, Kristof Egervari, Margot Piccinno, Ghazal Shammas, Alexandre Mariotte, Nicolas Fonta, Nicolas Liaudet, Danielle Shlesinger, Anna Rita Liuzzi, Ingrid Wagner, Cynthia Saadi, Christine Stadelmann, Sai T Reddy, Burkhard Becher, Doron Merkler
Tissue-resident memory CD8 + T cells cooperate with CD4 + T cells to drive compartmentalized immunopathology in the CNS. Science translational medicine 14 (640) (2022)
Peter Reuther, Katrin Martin, Mario Kreutzfeldt, Matias Ciancaglini, Florian Geier, Diego Calabrese, Doron Merkler, Daniel D Pinschewer
Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints. The Journal of experimental medicine 218 (10) (2021)
Giuseppe Ercolano, Alejandra Gomez-Cadena, Nina Dumauthioz, Giulia Vanoni, Mario Kreutzfeldt, Tania Wyss, Liliane Michalik, Romain Loyon, Angela Ianaro, Ping-Chih Ho, Christophe Borg, Manfred Kopf, Doron Merkler, Philippe Krebs, Pedro Romero, Sara Trabanelli, Camilla Jandus
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nature communications 12 (1) (2021)
Mehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero, Emily M Ullrich Gavilanes, Tradite Neziraj, Virág Kocsis-Jutka, Daniel Engels, Tanja Jürgens, Ingrid Wagner, Juan Daniel Flórez Weidinger, Stephanie S Schmidt, Eduardo Beltrán, Nellwyn Hagan, Lisa Woodworth, Dimitry Ofengeim, Joseph Gans, Fred Wolf, Mario Kreutzfeldt, Ruben Portugues, Doron Merkler, Thomas Misgeld, Martin Kerschensteiner
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation. Nature neuroscience 24 (3) (2021)
Nicolas Page, Sylvain Lemeille, Ilena Vincenti, Bogna Klimek, Alexandre Mariotte, Ingrid Wagner, Giovanni Di Liberto, Jonathan Kaye, Doron Merkler
Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling. Nature communications 12 (1) (2021)
Karin Steinbach, Ilena Vincenti, Kristof Egervari, Mario Kreutzfeldt, Franziska van der Meer, Nicolas Page, Bogna Klimek, Irène Rossitto-Borlat, Giovanni Di Liberto, Andreas Muschaweckh, Ingrid Wagner, Karim Hammad, Christine Stadelmann, Thomas Korn, Oliver Hartley, Daniel D Pinschewer, Doron Merkler
Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice. Science translational medicine 11 (498) (2020)
Bettina Stolp, Flavian Thelen, Xenia Ficht, Lukas M Altenburger, Nora Ruef, V V G Krishna Inavalli, Philipp Germann, Nicolas Page, Federica Moalli, Andrea Raimondi, Kirsten A Keyser, Seyed Morteza Seyed Jafari, Francesca Barone, Matthias S Dettmer, Doron Merkler, Matteo Iannacone, James Sharpe, Christoph Schlapbach, Oliver T Fackler, U Valentin Nägerl, Jens V Stein
Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance. Science immunology 5 (46) (2020)
Caroline Fecher, Laura Trovò, Stephan A Müller, Nicolas Snaidero, Jennifer Wettmarshausen, Sylvia Heink, Oskar Ortiz, Ingrid Wagner, Ralf Kühn, Jana Hartmann, Rosa Maria Karl, Arthur Konnerth, Thomas Korn, Wolfgang Wurst, Doron Merkler, Stefan F Lichtenthaler, Fabiana Perocchi, Thomas Misgeld
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. Nature neuroscience 22 (10) (2019)
Federica Moalli, Xenia Ficht, Philipp Germann, Mykhailo Vladymyrov, Bettina Stolp, Ingrid de Vries, Ruth Lyck, Jasmin Balmer, Amleto Fiocchi, Mario Kreutzfeldt, Doron Merkler, Matteo Iannacone, Akitaka Ariga, Michael Hubert Stoffel, James Sharpe, Martin Bähler, Michael Sixt, Alba Diz-Muñoz, Jens V Stein
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells. The Journal of experimental medicine 215 (7) (2018)
Karin Steinbach, Ilena Vincenti, Mario Kreutzfeldt, Nicolas Page, Andreas Muschaweckh, Ingrid Wagner, Ingo Drexler, Daniel Pinschewer, Thomas Korn, Doron Merkler
Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection. The Journal of experimental medicine 213 (8) (2016)
Aleksandra J Ozga, Federica Moalli, Jun Abe, Jim Swoger, James Sharpe, Dietmar Zehn, Mario Kreutzfeldt, Doron Merkler, Jorge Ripoll, Jens V Stein
pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion. The Journal of experimental medicine 213 (12) (2016)