Richard J P Brown

Scopus Author ID Scopus Author ID Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 15

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Microbiology spectrum

Journal of virology

Viruses

Paul-Ehrlich-Institut

Liverpool John Moores University (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Paul-Ehrlich-Institut Jan 01 2019

Germany

Group Leader :: Division of Veterinary Medicine

TWINCORE Zentrum für Experimentelle und Klinische Infektionsforschung GmbH Apr 01 2012 - Dec 31 2018

Germany

Senior post-doc :: Experimental Virology

University of Nottingham Aug 04 2003 - Jan 31 2012

United Kingdom

Post-doc :: School of Life Sciences

Education History

Liverpool John Moores University

United Kingdom

BSC :: School of Biomolecular Sciences

Publications

Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Rajendra Khanal, Natalie Heinen, Alexandra Bogomolova, Toni L Meister, Simon T Herrmann, Saskia Westhoven, Maximilian K Nocke, Daniel Todt, Freya Jockenhövel, Isabel M Klein, Laura Hartmann, Florian W R Vondran, Eike Steinmann, Gert Zimmer, Michael Ott, Richard J P Brown, Amar Deep Sharma, Stephanie Pfaender
MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2. Liver international : official journal of the International Association for the Study of the Liver (2024)
Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ola Bagato, Anne Balkema-Buschmann, Daniel Todt, Saskia Weber, André Gömer, Bingqian Qu, Csaba Miskey, Zoltán Ivics, Thomas C Mettenleiter, Stefan Finke, Richard J P Brown, Angele Breithaupt, Dmitry S Ushakov
Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs. Microbiology spectrum (2023)
Natalie Heinen, Rajendra Khanal, Saskia Westhoven, Mara Klöhn, Simon T Herrmann, Maike Herrmann, Tran Tuoc, Pauline Antonie Ulmke, Hoang Duy Nguyen, Hoa Huu Phuc Nguyen, Eike Steinmann, Daniel Todt, Richard J P Brown, Amar Deep Sharma, Stephanie Pfaender
Productive infection of primary human hepatocytes with SARS-CoV-2 induces antiviral and proinflammatory responses. Gut (2023)
Yudi Zhang, Volker Kinast, Julie Sheldon, Nicola Frericks, Daniel Todt, Matthias Zimmer, Neva Caliskan, Richard J P Brown, Eike Steinmann, Thomas Pietschmann
Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses. Microbiology spectrum (2023)
André Gömer, Richard J P Brown, Stephanie Pfaender, Katja Deterding, Gábor Reuter, Richard J Orton, Stefan Seitz, C-Thomas Bock, Jessika M V Cavalleri, Thomas Pietschmann, Heiner Wedemeyer, Eike Steinmann, Daniel Todt
Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance. Virus evolution 8 (1) (2022)
Birthe Reinecke, Nicola Frericks, Chris Lauber, Katja Dinkelborg, Alina Matthaei, Florian W R Vondran, Patrick Behrendt, Sibylle Haid, Richard J P Brown, Thomas Pietschmann
The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection. Journal of virology 96 (7) (2022)
Fabian Höing, Dylan Postmus, Richard J P Brown, Emanuel Wyler, Elena Neumann, Markus Landthaler, Christine Goffinet
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression. Emerging microbes & infections 10 (1) (2022)
Bingqian Qu, Richard J P Brown
Strategies to Inhibit Hepatitis B Virus at the Transcript Level. Viruses 13 (7) (2021)
Jan Felix Drexler, Gabrielle Vieyres, Daniel Todt, Chris Lauber, Corinne Ginkel, Michael Engelmann, Maike Herrmann, Christian K Pfaller, Florian W R Vondran, Ruth Broering, Ehsan Vafadarnejad, Antoine-Emmanuel Saliba, Christina Puff, Wolfgang Baumgärtner, Csaba Miskey, Zoltán Ivics, Eike Steinmann, Thomas Pietschmann, Richard J P Brown
Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements. Journal of virology (2021)
Richard J P Brown, Jan Felix Drexler, Julie Sheldon, Tanvi Khera, null Anggakusuma, Daniel Todt, Gabrielle Vieyres, Romy Weller, Sebastian Joecks, Yudi Zhang, Svenja Sake, Dorothea Bankwitz, Kathrin Welsch, Corinne Ginkel, Michael Engelmann, Gisa Gerold, Eike Steinmann, Qinggong Yuan, Michael Ott, Florian W R Vondran, Thomas Krey, Luisa J Ströh, Csaba Miskey, Zoltán Ivics, Vanessa Herder, Wolfgang Baumgärtner, Chris Lauber, Michael Seifert, Alexander W Tarr, C Patrick McClure, Glenn Randall, Yasmine Baktash, Alexander Ploss, Viet Loan Dao Thi, Eleftherios Michailidis, Mohsan Saeed, Lieven Verhoye, Philip Meuleman, Natascha Goedecke, Dagmar Wirth, Charles M Rice, Thomas Pietschmann
Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Science advances 6 (45) (2020)
Robin D V Kleinert, Eduardo Montoya-Diaz, Tanvi Khera, Kathrin Welsch, Jan Felix Drexler, Sebastian Hoehl, Sandra Ciesek, Richard J P Brown
Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus. Viruses 11 (10) (2019)
Volker Kinast, Stefan L Leber, Richard J P Brown, Gabrielle Vieyres, Patrick Behrendt, Constanze Eßbach, Pavel Strnad, Florian W R Vondran, Markus Cornberg, Cora Wex, Thomas Pietschmann, Johannes Haybaeck, Daniel Todt, Eike Steinmann
Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver. Cells 8 (6) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Richard J P Brown