Christine Goffinet

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 34

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature microbiology

Cellular and molecular life sciences : CMLS

Nature biotechnology

Charité Universitätsmedizin Berlin

Heidelberg University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Charité Universitätsmedizin Berlin Feb 01 2019

Germany

Associate Professor :: Institute of Virology

TWINCORE Zentrum für Experimentelle und Klinische Infektionsforschung GmbH Nov 01 2013 - Jan 31 2019

Germany

Assistant Professor :: Institute of Experimental Virology

Ulm University Nov 01 2010 - Oct 31 2013

Germany

Junior Group Leader :: Institute of Molecular Virology

Heidelberg University Jun 01 2007 - Oct 31 2010

Germany

Postdoctoral Fellow :: Department of Infectiology

Education History

Heidelberg University Jan 15 2004 - May 31 2007

Germany

PHD :: Department of Infectiology

Publications

Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Saba Mottaghinia, Saskia Stenzel, Kyriakos Tsangaras, Nikolas Nikolaidis, Michael Laue, Karin Müller, Henriette Hölscher, Ulrike Loeber, Gayle K McEwen, Stephen C Donnellan, Kevin C Rowe, Ken P Aplin, Christine Goffinet, Alex David Greenwood
A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea. Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Bingqian Qu, Csaba Miskey, André Gömer, Robin D V Kleinert, Sara Calvo Ibanez, Regina Eberle, Aileen Ebenig, Dylan Postmus, Maximilian K Nocke, Maike Herrmann, Tabitha K Itotia, Simon T Herrmann, Natalie Heinen, Sebastian Höck, Florian D Hastert, Christine von Rhein, Christoph Schürmann, Xue Li, Ger van Zandbergen, Marek Widera, Sandra Ciesek, Barbara S Schnierle, Alexander W Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D Mühlebach, Daniel Todt, Richard J P Brown
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution. Proceedings of the National Academy of Sciences of the United States of America 121 (23) (2024)
Ruediger Gross, Hanna Reßin, Pascal von Maltitz, Dan P J Albers, Laura Schneider, Hanna Bley, Markus Hoffmann, Mirko Cortese, Dhanu Gupta, Miriam Deniz, Jae-Yeon Choi, Jenny Jansen, Christian Preußer, Kai Seehafer, Stefan H Pöhlmann, Dennis R Voelker, Christine Goffinet, Elke Pogge-von Strandmann, Uwe Bunz, Ralf F W Bartenschlager, Samir El Andaloussi, Konstantin Maria Johannes Sparrer, Eva Herker, Stephan Becker, Frank Kirchhoff, Jan Münch, Janis A Müller
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nature microbiology 9 (4) (2024)
Baxolele Mhlekude, Dylan Postmus, Saskia Stenzel, January Weiner, Jenny Jansen, Francisco J Zapatero-Belinchón, Ruth Olmer, Anja Richter, Julian Heinze, Nicolas Heinemann, Barbara Mühlemann, Simon Schroeder, Terry C Jones, Marcel A Müller, Christian Drosten, Andreas Pich, Volker Thiel, Ulrich Martin, Daniela Niemeyer, Gisa Gerold, Dieter Beule, Christine Goffinet
Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection. PLoS pathogens 19 (9) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Geraldine Nouailles, Julia Maria Adler, Peter Pennitz, Stefan Peidli, Luiz Gustavo Teixeira Alves, Morris Baumgardt, Judith Bushe, Anne Voss, Alina Langenhagen, Christine Langner, Ricardo Martin Vidal, Fabian Höing, Julia Kazmierski, Aileen Ebenig, Mona V Lange, Michael D Mühlebach, Cengiz Goekeri, Szandor Simmons, Na Xing, Azza Abdelgawad, Susanne Herwig, Günter Cichon, Daniela Niemeyer, Christian Drosten, Christine Goffinet, Markus Landthaler, Nils Blüthgen, Haibo Wu, Martin Witzenrath, Achim D Gruber, Samantha D Praktiknjo, Nikolaus Osterrieder, Emanuel Wyler, Dusan Kunec, Jakob Trimpert
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters. Nature microbiology (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Sarah Krieg, Fabian Höing, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication. Cellular and molecular life sciences : CMLS 80 (3) (2023)
Bengisu Akbil, Tim Meyer, Paula Stubbemann, Charlotte Thibeault, Olga Staudacher, Daniela Niemeyer, Jenny Jansen, Barbara Mühlemann, Jan Doehn, Christoph Tabeling, Christian Nusshag, Cédric Hirzel, David Sökler Sanchez, Alexandra Nieters, Achim Lother, Daniel Duerschmied, Nils Schallner, Jan Nikolaus Lieberum, Dietrich August, Siegbert Rieg, Valeria Falcone, Hartmut Hengel, Uwe Kölsch, Nadine Unterwalder, Ralf-Harto Hübner, Terry C Jones, Norbert Suttorp, Christian Drosten, Klaus Warnatz, Thibaud Spinetti, Joerg C Schefold, Thomas Dörner, Leif Erik Sander, Victor M Corman, Uta Merle, null null, Florian Kurth, Horst von Bernuth, Christian Meisel, Christine Goffinet
Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies. Journal of clinical immunology 42 (6) (2022)
Julia Kazmierski, Kirstin Friedmann, Dylan Postmus, Jackson Emanuel, Cornelius Fischer, Jenny Jansen, Anja Richter, Laure Bosquillon de Jarcy, Christiane Schüler, Madlen Sohn, Sascha Sauer, Christian Drosten, Antoine-Emmanuel Saliba, Leif Erik Sander, Marcel Alexander Müller, Daniela Niemeyer, Christine Goffinet
Nonproductive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immune responses. Molecular systems biology 18 (8) (2022)
Daniela Niemeyer, Saskia Stenzel, Talitha Veith, Simon Schroeder, Kirstin Friedmann, Friderike Weege, Jakob Trimpert, Julian Heinze, Anja Richter, Jenny Jansen, Jackson Emanuel, Julia Kazmierski, Fabian Pott, Lara M Jeworowski, Ruth Olmer, Mark-Christian Jaboreck, Beate Tenner, Jan Papies, Felix Walper, Marie L Schmidt, Nicolas Heinemann, Elisabeth Möncke-Buchner, Morris Baumgardt, Karen Hoffmann, Marek Widera, Tran Thi Nhu Thao, Anita Balázs, Jessica Schulze, Christin Mache, Terry C Jones, Markus Morkel, Sandra Ciesek, Leif G Hanitsch, Marcus A Mall, Andreas C Hocke, Volker Thiel, Klaus Osterrieder, Thorsten Wolff, Ulrich Martin, Victor M Corman, Marcel A Müller, Christine Goffinet, Christian Drosten
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression. PLoS biology 20 (11) (2022)
Julia Kazmierski, Carina Elsner, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Fabian Höing, Jenny Jansen, Christian W Thorball, Ole Zeymer, Xiaoyi Zhou, Roman Fedorov, Jacques Fellay, Markus W Löffler, Alexander N R Weber, Beate Sodeik, Christine Goffinet
A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913. Journal of immunology (Baltimore, Md. : 1950) (2022)
Fabian Höing, Dylan Postmus, Richard J P Brown, Emanuel Wyler, Elena Neumann, Markus Landthaler, Christine Goffinet
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression. Emerging microbes & infections 10 (1) (2022)
Sergej Franz, Fabian Höing, Thomas Zillinger, Christiane Schüler, Sandra Dapa, Carlo Fischer, Vânia Passos, Saskia Stenzel, Fangfang Chen, Katinka Döhner, Gunther Hartmann, Beate Sodeik, Frank Pessler, Graham Simmons, Jan Felix Drexler, Christine Goffinet
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction. Life science alliance 4 (7) (2021)
Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger, Desiree Schütz, Sandra Heller, Christina M Stürzel, Dorota Kmiec, Carina Conzelmann, Janis A Müller, Fabian Zech, Elisabeth Braun, Ruediger Gross, Lukas Wettstein, Tatjana Weil, Johanna Weiß, Federica Diofano, Armando Alexei Rodríguez, Sebastian Wiese, Daniel Sauter, Jan Münch, Christine Goffinet, Alberto Catanese, Michael Schön, Tobias M Böckers, Steffen Stenger, Kei Sato, Steffen Just, Alexander Kleger, Konstantin Maria Johannes Sparrer, Frank Kirchhoff
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Nature communications 12 (1) (2021)
Geraldine Nouailles, Emanuel Wyler, Peter Pennitz, Dylan Postmus, Daria Vladimirova, Julia Kazmierski, Fabian Höing, Kristina Dietert, Michael Muelleder, Vadim Farztdinov, Benedikt Obermayer, Sandra-Maria Wienhold, Sandro Andreotti, Thomas Höfler, Birgit Sawitzki, Christian Drosten, Leif-Erik Sander, Norbert Suttorp, Markus Ralser, Dieter Beule, Achim D Gruber, Christine Goffinet, Markus Landthaler, Jakob Trimpert, Martin Witzenrath
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19. Nature communications 12 (1) (2021)
Saskia Trump, Soeren Lukassen, Markus S Anker, Robert Lorenz Chua, Johannes Liebig, Loreen Thürmann, Victor Max Corman, Marco Binder, Jennifer Loske, Christina Klasa, Teresa Krieger, Bianca P Hennig, Marey Messingschlager, Fabian Höing, Julia Kazmierski, Sven Twardziok, Jan Philipp Albrecht, Jürgen Eils, Sara Hadzibegovic, Alessia Lena, Bettina Heidecker, Thore Bürgel, Jakob Steinfeldt, Christine Goffinet, Florian Kurth, Martin Witzenrath, Maria Theresa Völker, Sarah Dorothea Müller, Uwe Gerd Liebert, Naveed Ishaque, Lars Kaderali, Leif-Erik Sander, Christian Drosten, Sven Laudi, Roland Eils, Christian Conrad, Ulf Landmesser, Irina Lehmann
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19. Nature biotechnology 39 (6) (2020)
Carina Elsner, Aparna Ponnurangam, Julia Kazmierski, Thomas Zillinger, Jenny Jansen, Daniel Todt, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Nils Kriedemann, Angelina Malassa, Pia-Katharina Larsen, Gunther Hartmann, Winfried Barchet, Eike Steinmann, Ulrich Kalinke, Beate Sodeik, Christine Goffinet
Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells. Proceedings of the National Academy of Sciences of the United States of America 117 (32) (2020)
Robert Lorenz Chua, Soeren Lukassen, Saskia Trump, Bianca P Hennig, Daniel Wendisch, Fabian Höing, Olivia Debnath, Loreen Thürmann, Florian Kurth, Maria Theresa Völker, Julia Kazmierski, Bernd Timmermann, Sven Twardziok, Stefan Schneider, Felix Machleidt, Holger Müller-Redetzky, Melanie Maier, Alexander Krannich, Sein Schmidt, Felix Balzer, Johannes Liebig, Jennifer Loske, Norbert Suttorp, Jürgen Eils, Naveed Ishaque, Uwe Gerd Liebert, Christof von Kalle, Andreas Hocke, Martin Witzenrath, Christine Goffinet, Christian Drosten, Sven Laudi, Irina Lehmann, Christian Conrad, Leif-Erik Sander, Roland Eils
COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. Nature biotechnology 38 (8) (2020)
Vânia Passos, Thomas Zillinger, Nicoletta Casartelli, Amelie S Wachs, Shuting Xu, Angelina Malassa, Katja Steppich, Hildegard Schilling, Sergej Franz, Daniel Todt, Eike Steinmann, Kathrin Sutter, Ulf Dittmer, Jens Bohne, Olivier Schwartz, Winfried Barchet, Christine Goffinet
Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor. Journal of virology 93 (24) (2019)

Christine Goffinet.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Christine Goffinet