Roger D Cone (R D Cone)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 23

Top Topics

Bariatric Surgery

Top Venues

bioRxiv : the preprint server for biology

Journal of medicinal chemistry

Journal of neuroendocrinology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Alys Peisley, Ciria C Hernandez, Naima S Dahir, Laura Koepping, Ashleigh M Raczkowski, Min Su, Masoud Ghamari-Langroudi, Xinrui Ji, Luis E Gimenez, Roger D Cone
Structure of the Ion Channel Kir7.1 and Implications for its Function in Normal and Pathophysiologic States. bioRxiv : the preprint server for biology (2024)
Luis E Gimenez, Charlotte Martin, Jing Yu, Charlie Hollanders, Ciria C Hernandez, Yiran Wu, Deqiang Yao, Gye Won Han, Naima S Dahir, Lijie Wu, Olivier Van der Poorten, Arthur Lamouroux, Morgane Mannes, Suwen Zhao, Dirk Tourwé, Raymond C Stevens, Roger D Cone, Steven Ballet
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. Journal of medicinal chemistry (2024)
Li Li, Ciria C Hernandez, Luis E Gimenez, Baijie Xu, Naima S Dahir, null Swati, Shari G Birnbaum, Roger D Cone, Chen Liu
Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced hyperphagia. bioRxiv : the preprint server for biology (2024)
Alys Peisley, Ciria C Hernandez, Naima S Dahir, Laura Koepping, Ashleigh M Raczkowski, Min Su, Masoud Ghamari-Langroudi, Xinrui Ji, Luis E Gimenez, Roger D Cone
Structure of the Ion Channel Kir7.1 and Implications for its Function in Normal and Pathophysiologic States. bioRxiv : the preprint server for biology (2024)
Li Li, Ciria C Hernandez, Luis E Gimenez, Baijie Xu, Naima S Dahir, null Swati, Shari G Birnbaum, Roger D Cone, Chen Liu
Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced hyperphagia. bioRxiv : the preprint server for biology (2024)
Luis E Gimenez, Charlotte Martin, Jing Yu, Charlie Hollanders, Ciria C Hernandez, Yiran Wu, Deqiang Yao, Gye Won Han, Naima S Dahir, Lijie Wu, Olivier Van der Poorten, Arthur Lamouroux, Morgane Mannes, Suwen Zhao, Dirk Tourwé, Raymond C Stevens, Roger D Cone, Steven Ballet
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. Journal of medicinal chemistry 67 (4) (2024)
Alys Peisley, Ciria C Hernandez, Naima S Dahir, Laura Koepping, Ashleigh M Raczkowski, Min Su, Masoud Ghamari-Langroudi, Xinrui Ji, Luis E Gimenez, Roger D Cone
Structure of the Ion Channel Kir7.1 and Implications for its Function in Normal and Pathophysiologic States. bioRxiv : the preprint server for biology (2024)
Luis E Gimenez, Charlotte Martin, Jing Yu, Charlie Hollanders, Ciria C Hernandez, Yiran Wu, Deqiang Yao, Gye Won Han, Naima S Dahir, Lijie Wu, Olivier Van der Poorten, Arthur Lamouroux, Morgane Mannes, Suwen Zhao, Dirk Tourwé, Raymond C Stevens, Roger D Cone, Steven Ballet
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. Journal of medicinal chemistry 67 (4) (2024)
Naima S Dahir, Yijun Gui, Yanan Wu, Patrick R Sweeney, Savannah Y Williams, Luis E Gimenez, Tomi K Sawyer, Stephen T Joy, Anna K Mapp, Roger D Cone
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv : the preprint server for biology (2023)
Naima S Dahir, Yijun Gui, Yanan Wu, Patrick R Sweeney, Savannah Y Williams, Luis E Gimenez, Tomi K Sawyer, Stephen T Joy, Anna K Mapp, Roger D Cone
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv : the preprint server for biology (2023)
Naima S Dahir, Yijun Gui, Yanan Wu, Patrick R Sweeney, Savannah Y Williams, Luis E Gimenez, Tomi K Sawyer, Stephen T Joy, Anna K Mapp, Roger D Cone
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv : the preprint server for biology (2023)
Naima S Dahir, Yijun Gui, Yanan Wu, Patrick R Sweeney, Savannah Y Williams, Luis E Gimenez, Tomi K Sawyer, Stephen T Joy, Anna K Mapp, Roger D Cone
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv : the preprint server for biology (2023)
Yijun Gui, Naima S Dahir, Griffin Downing, Patrick Sweeney, Roger D Cone
Cell autonomous regulation of the activation of AgRP neurons by the melanocortin-3 receptor. bioRxiv : the preprint server for biology (2023)
Naima S Dahir, Yijun Gui, Yanan Wu, Patrick R Sweeney, Savannah Y Williams, Luis E Gimenez, Tomi K Sawyer, Stephen T Joy, Anna K Mapp, Roger D Cone
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv : the preprint server for biology (2023)
Patrick Sweeney, Luis E Gimenez, Ciria C Hernandez, Roger D Cone
Targeting the central melanocortin system for the treatment of metabolic disorders. Nature reviews. Endocrinology (2023)
Luis E Gimenez, Terry A Noblin, Savannah Y Williams, Satarupa Mullick Bagchi, Ren-Lei Ji, Ya-Xiong Tao, Claus B Jeppesen, Kilian W Conde-Frieboes, Tomi K Sawyer, Paolo Grieco, Roger D Cone
Demonstration of a Common DPhe 7 to DNal(2') 7 Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides. Journal of medicinal chemistry 65 (8) (2022)
Işın Çakır, Colleen K Hadley, Pauline Lining Pan, Rushita A Bagchi, Masoud Ghamari-Langroudi, Danielle T Porter, Qiuyu Wang, Michael J Litt, Somnath Jana, Susan Hagen, Pil Lee, Andrew White, Jiandie D Lin, Timothy A McKinsey, Roger D Cone
Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity. Nature metabolism 4 (1) (2022)
Brian Yee Hong Lam, Alice Williamson, Sarah Finer, Felix R Day, John A Tadross, A Gonçalves Soares, Kaitlin H Wade, P Sweeney, M N Bedenbaugh, Danielle T Porter, A Melvin, K L J Ellacott, R N Lippert, S Buller, J Rosmaninho-Salgado, G K C Dowsett, K E Ridley, Z Xu, Irene Cimino, D Rimmington, K Rainbow, K Duckett, Staffan Holmqvist, A Khan, X Dai, E G Bochukova, null null, R C Trembath, Hilary C Martin, A P Coll, David H Rowitch, Nicholas J Wareham, David A van Heel, Nicholas John Timpson, Richard B Simerly, Ken K Ong, Roger D Cone, Claudia Langenberg, John R B Perry, Giles S H Yeo, Stephen I O'Rahilly
MC3R links nutritional state to childhood growth and the timing of puberty. Nature 599 (7885) (2021)
Jing Yu, Luis E Gimenez, Ciria C Hernandez, Yiran Wu, Ariel H Wein, Gye Won Han, Kyle McClary, Sanraj R Mittal, Kylie Burdsall, Benjamin Stauch, Li-Jie Wu, Sophia N Stevens, Alys Peisley, Savannah Y Williams, Valerie Chen, Glenn L Millhauser, Suwen Zhao, Roger D Cone, Raymond C Stevens
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding. Science (New York, N.Y.) 368 (6489) (2020)
Taneisha Gillyard, Katelyn Fowler, Savannah Y Williams, Roger D Cone
Obesity-associated mutant melanocortin-4 receptors with normal Gαs coupling frequently exhibit other discoverable pharmacological and biochemical defects. Journal of neuroendocrinology 31 (10) (2019)
Erica J P Anderson, Masoud Ghamari-Langroudi, Isin Cakir, Michael J Litt, Valerie Chen, Roman E Reggiardo, Glenn L Millhauser, Roger D Cone
Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. Journal of neuroendocrinology 31 (1) (2019)
Masoud Ghamari-Langroudi, Işın Çakır, Rachel N Lippert, Patrick Sweeney, Michael J Litt, Kate L J Ellacott, Roger D Cone
Regulation of energy rheostasis by the melanocortin-3 receptor. Science advances 4 (8) (2018)
Michael J Litt, G Donald Okoye, Daniel Lark, Isin Cakir, Christy Moore, Mary C Barber, James Atkinson, Josh Fessel, Javid Moslehi, Roger D Cone
Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy. eLife 6 (2017)