Roland Beckmann

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 60

Top Topics

Acute Myeloid Leukemia

Structural Basis

Saccharomyces Cerevisiae

Top Venues

Nature communications

The EMBO journal

Nature structural & molecular biology

This page only lists publications with an associated author ORCID identifier.

Publications

Xiang Li, Mengjiao Wang, Timo Denk, Robert Buschauer, Yi Li, Roland Beckmann, Jingdong Cheng
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nature communications 15 (1) (2024)
Paul A DaRosa, Ivan Penchev, Samantha C Gumbin, Francesco Scavone, Magda Wąchalska, Joao A Paulo, Alban Ordureau, Joshua J Peter, Yogesh Kulathu, J Wade Harper, Thomas A Becker, Roland Beckmann, Ron R Kopito
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature 627 (8003) (2024)
Xiang Li, Mengjiao Wang, Timo Denk, Robert Buschauer, Yi Li, Roland Beckmann, Jingdong Cheng
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nature communications 15 (1) (2024)
Paul A DaRosa, Ivan Penchev, Samantha C Gumbin, Francesco Scavone, Magda Wąchalska, Joao A Paulo, Alban Ordureau, Joshua J Peter, Yogesh Kulathu, J Wade Harper, Thomas A Becker, Roland Beckmann, Ron R Kopito
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature 627 (8003) (2024)
Paul A DaRosa, Ivan Penchev, Samantha C Gumbin, Francesco Scavone, Magda Wąchalska, Joao A Paulo, Alban Ordureau, Joshua J Peter, Yogesh Kulathu, J Wade Harper, Thomas A Becker, Roland Beckmann, Ron R Kopito
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature 627 (8003) (2024)
Xiang Li, Mengjiao Wang, Timo Denk, Robert Buschauer, Yi Li, Roland Beckmann, Jingdong Cheng
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nature communications 15 (1) (2024)
Paul A DaRosa, Ivan Penchev, Samantha C Gumbin, Francesco Scavone, Magda Wąchalska, Joao A Paulo, Alban Ordureau, Joshua J Peter, Yogesh Kulathu, J Wade Harper, Thomas A Becker, Roland Beckmann, Ron R Kopito
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature 627 (8003) (2024)
Paul A DaRosa, Ivan Penchev, Samantha C Gumbin, Francesco Scavone, Magda Wąchalska, Joao A Paulo, Alban Ordureau, Joshua J Peter, Yogesh Kulathu, J Wade Harper, Thomas A Becker, Roland Beckmann, Ron R Kopito
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature (2024)
Matthias Thoms, Benjamin Lau, Jingdong Cheng, Lisa Fromm, Timo Denk, Nikola Kellner, Dirk Flemming, Paulina Fischer, Laurent Falquet, Otto Berninghausen, Roland Beckmann, Ed Hurt
Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. EMBO reports (2023)
Benjamin Lau, Zixuan Huang, Nikola Kellner, Shuangshuang Niu, Otto Berninghausen, Roland Beckmann, Ed Hurt, Jingdong Cheng
Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. EMBO reports (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal (2023)
Ken Ikeuchi, Nives Ivic, Robert Buschauer, Jingdong Cheng, Fröhlich Thomas, Yoshitaka Matsuo, Otto Berninghausen, Toshifumi Inada, Thomas A Becker, Roland Beckmann
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nature communications 14 (1) (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal (2023)
Ken Ikeuchi, Nives Ivic, Robert Buschauer, Jingdong Cheng, Fröhlich Thomas, Yoshitaka Matsuo, Otto Berninghausen, Toshifumi Inada, Thomas A Becker, Roland Beckmann
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nature communications 14 (1) (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal (2023)
Katharina Best, Ken Ikeuchi, Lukas Kater, Daniel Best, Joanna Musial, Yoshitaka Matsuo, Otto Berninghausen, Thomas Becker, Toshifumi Inada, Roland Beckmann
Structural basis for clearing of ribosome collisions by the RQT complex. Nature communications 14 (1) (2023)
Valentin Mitterer, Matthias Thoms, Robert Buschauer, Otto Berninghausen, Ed Hurt, Roland Beckmann
Concurrent remodeling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase. eLife 12 (2023)
Katharina Best, Ken Ikeuchi, Lukas Kater, Daniel Best, Joanna Musial, Yoshitaka Matsuo, Otto Berninghausen, Thomas Becker, Toshifumi Inada, Roland Beckmann
Structural basis for clearing of ribosome collisions by the RQT complex. Nature communications 14 (1) (2023)
Ken Ikeuchi, Nives Ivic, Robert Buschauer, Jingdong Cheng, Fröhlich Thomas, Yoshitaka Matsuo, Otto Berninghausen, Toshifumi Inada, Thomas A Becker, Roland Beckmann
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nature communications 14 (1) (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal 43 (4) (2023)
Valentin Mitterer, Matthias Thoms, Robert Buschauer, Otto Berninghausen, Ed Hurt, Roland Beckmann
Concurrent remodeling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase. eLife 12 (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal 43 (4) (2023)
Katharina Best, Ken Ikeuchi, Lukas Kater, Daniel Best, Joanna Musial, Yoshitaka Matsuo, Otto Berninghausen, Thomas Becker, Toshifumi Inada, Roland Beckmann
Structural basis for clearing of ribosome collisions by the RQT complex. Nature communications 14 (1) (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal 43 (4) (2023)
Alexandra G Knorr, Timur Mackens-Kiani, Joanna Musial, Otto Berninghausen, Thomas Becker, Birgitta Beatrix, Roland Beckmann
The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. PLoS biology 21 (4) (2023)
Ken Ikeuchi, Nives Ivic, Robert Buschauer, Jingdong Cheng, Fröhlich Thomas, Yoshitaka Matsuo, Otto Berninghausen, Toshifumi Inada, Thomas A Becker, Roland Beckmann
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nature communications 14 (1) (2023)
Esther N Park, Timur Mackens-Kiani, Rebekah Berhane, Hanna Esser, Chimeg Erdenebat, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Roland Beckmann, Rachel Green, Allen R Buskirk
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. The EMBO journal (2023)
Nestor Miguel Castillo Duque de Estrada, Matthias Thoms, Dirk Flemming, Henrik M Hammarén, Robert Buschauer, Michael Ameismeier, Jochen Baßler, Martin Beck, Roland Beckmann, Ed Hurt
Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways. Nature structural & molecular biology (2023)
Katharina Best, Ken Ikeuchi, Lukas Kater, Daniel Best, Joanna Musial, Yoshitaka Matsuo, Otto Berninghausen, Thomas Becker, Toshifumi Inada, Roland Beckmann
Structural basis for clearing of ribosome collisions by the RQT complex. Nature communications 14 (1) (2023)
Fengbiao Zhou, Nesrine Aroua, Yi Liu, Christian Rohde, Jingdong Cheng, Anna-Katharina Wirth, Daria Fijalkowska, Stefanie Göllner, Michelle Lotze, Haiyang Yun, Xiaobing Yu, Caroline Pabst, Tim Sauer, Thomas Oellerich, Hubert Serve, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia Dorothea Baldus, Michaela Frye, Simon Raffel, Jeroen Krijgsveld, Irmela Jeremias, Roland Beckmann, Flavia Carla Meotti, Carsten Muller-Tidow
A dynamic rRNA ribomethylome drives stemness in acute myeloid leukemia. Cancer discovery (2022)
Minkoo Ahn, Tomasz Włodarski, Alkistis Mitropoulou, Sammy H S Chan, Haneesh Sidhu, Elena Plessa, Thomas A Becker, Nediljko Budisa, Christopher A Waudby, Roland Beckmann, Anaïs M E Cassaignau, Lisa D Cabrita, John Christodoulou
Modulating co-translational protein folding by rational design and ribosome engineering. Nature communications 13 (1) (2022)
Kazuki Saito, Hanna Kratzat, Annabelle Campbell, Robert Buschauer, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Rachel Green, Roland Beckmann, Allen R Buskirk
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature 603 (7901) (2022)
Momoko Narita, Timo Denk, Yoshitaka Matsuo, Takato Sugiyama, Chisato Kikuguchi, Sota Ito, Nichika Sato, Toru Suzuki, Satoshi Hashimoto, Iva Machová, Petr Tesina, Roland Beckmann, Toshifumi Inada
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation. Nature communications 13 (1) (2022)
Laura Czech, Christopher Nils Mais, Hanna Kratzat, Pinku Sarmah, Pietro Giammarinaro, Sven Andreas Freibert, Hanna Folke Esser, Joanna Musial, Otto Berninghausen, Wieland Steinchen, Roland Beckmann, Hans-Georg Koch, Gert Bange
Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nature communications 13 (1) (2022)
Minkoo Ahn, Tomasz Włodarski, Alkistis Mitropoulou, Sammy H S Chan, Haneesh Sidhu, Elena Plessa, Thomas A Becker, Nediljko Budisa, Christopher A Waudby, Roland Beckmann, Anaïs M E Cassaignau, Lisa D Cabrita, John Christodoulou
Author Correction: Modulating co-translational protein folding by rational design and ribosome engineering. Nature communications 13 (1) (2022)
Jian Lei, Yue Ma-Lauer, Yinze Han, Matthias Thoms, Robert Buschauer, Joerg Jores, Volker Thiel, Roland Beckmann, Wen Deng, Heinrich Leonhardt, Rolf Hilgenfeld, Albrecht von Brunn
The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. The EMBO journal 40 (11) (2021)
Jingdong Cheng, Otto Berninghausen, Roland Beckmann
A distinct assembly pathway of the human 39S late pre-mitoribosome. Nature communications 12 (1) (2021)
Niladri K Sinha, Alban Ordureau, Katharina Best, James A Saba, Boris Zinshteyn, Elayanambi Sundaramoorthy, Amit Fulzele, Danielle M Garshott, Timo Denk, Matthias Thoms, Joao A Paulo, J Wade Harper, Eric J Bennett, Roland Beckmann, Rachel Green
EDF1 coordinates cellular responses to ribosome collisions. eLife 9 (2020)
Jennifer N Wells, Robert Buschauer, Timur Mackens-Kiani, Katharina Best, Hanna Kratzat, Otto Berninghausen, Thomas Becker, Wendy V Gilbert, Jingdong Cheng, Roland Beckmann
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. PLoS biology 18 (7) (2020)
Tsai-Hsuan Weng, Wieland Steinchen, Birgitta Beatrix, Otto Berninghausen, Thomas A Becker, Gert Bange, Jingdong Cheng, Roland Beckmann
Architecture of the active post-translational Sec translocon. The EMBO journal 40 (3) (2020)
Jingdong Cheng, Benjamin Lau, Giuseppe La Venuta, Michael Ameismeier, Otto Berninghausen, Ed Hurt, Roland Beckmann
90S pre-ribosome transformation into the primordial 40S subunit. Science (New York, N.Y.) 369 (6510) (2020)
Lukas Kater, Nikola Wagener, Otto Berninghausen, Thomas A Becker, Walter Neupert, Roland Beckmann
Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins. Nature structural & molecular biology 27 (2) (2020)
Michael Ameismeier, Ivo Zemp, Jasmin van den Heuvel, Matthias Thoms, Otto Berninghausen, Ulrike Kutay, Roland Beckmann
Structural basis for the final steps of human 40S ribosome maturation. Nature 587 (7835) (2020)
Matthias Thoms, Robert Buschauer, Michael Ameismeier, Lennart Koepke, Timo Denk, Maximilian Hirschenberger, Hanna Kratzat, Manuel Hayn, Timur Mackens-Kiani, Jingdong Cheng, Jan H Straub, Christina M Stürzel, Fröhlich Thomas, Otto Berninghausen, Thomas A Becker, Frank Kirchhoff, Konstantin Maria Johannes Sparrer, Roland Beckmann
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science (New York, N.Y.) 369 (6508) (2020)
Hanna Kratzat, Timur Mackens-Kiani, Michael Ameismeier, Mia Potocnjak, Jingdong Cheng, Estelle Dacheux, Abdelkader Namane, Otto Berninghausen, Franz Herzog, Micheline Fromont-Racine, Thomas A Becker, Roland Beckmann
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. The EMBO journal 40 (1) (2020)
Robert Buschauer, Yoshitaka Matsuo, Takato Sugiyama, Ying-Hsin Chen, Najwa Alhusaini, Thomas Sweet, Ken Ikeuchi, Jingdong Cheng, Yasuko Matsuki, Risa Nobuta, Andrea Gilmozzi, Otto Berninghausen, Petr Tesina, Thomas A Becker, Jeff Coller, Toshifumi Inada, Roland Beckmann
The Ccr4-Not complex monitors the translating ribosome for codon optimality. Science (New York, N.Y.) 368 (6488) (2020)
Elina Nürenberg-Goloub, Hanna Kratzat, Holger Heinemann, André Heuer, Peter Kötter, Otto Berninghausen, Thomas A Becker, Robert Tampé, Roland Beckmann
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex. The EMBO journal 39 (9) (2020)
Yoshitaka Matsuo, Petr Tesina, Shizuka Nakajima, Masato Mizuno, Akinori Endo, Robert Buschauer, Jingdong Cheng, Okuto Shounai, Ken Ikeuchi, Yasushi Saeki, Thomas A Becker, Roland Beckmann, Toshifumi Inada
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nature structural & molecular biology 27 (4) (2020)
Vivekanandan Shanmuganathan, Nina Schiller, Anastasia Magoulopoulou, Jingdong Cheng, Katharina Braunger, Florian Cymer, Otto Berninghausen, Birgitta Beatrix, Kenji Kohno, Gunnar von Heijne, Roland Beckmann
Structural and mutational analysis of the ribosome-arresting human XBP1u. eLife 8 (2019)
Lukas Kater, Benedikt Frieg, Otto Berninghausen, Holger Gohlke, Roland Beckmann, Alexej Kedrov
Partially inserted nascent chain unzips the lateral gate of the Sec translocon. EMBO reports 20 (10) (2019)
Ken Ikeuchi, Petr Tesina, Yoshitaka Matsuo, Takato Sugiyama, Jingdong Cheng, Yasushi Saeki, Keiji Tanaka, Thomas A Becker, Roland Beckmann, Toshifumi Inada
Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. The EMBO journal 38 (5) (2019)
Petr Tesina, Laura N Lessen, Robert Buschauer, Jingdong Cheng, Colin Chih-Chien Wu, Otto Berninghausen, Allen R Buskirk, Thomas A Becker, Roland Beckmann, Rachel Green
Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. The EMBO journal 39 (3) (2019)
Petr Tesina, Elisabeth Heckel, Jingdong Cheng, Micheline Fromont-Racine, Robert Buschauer, Lukas Kater, Birgitta Beatrix, Otto Berninghausen, Alain Jacquier, Thomas A Becker, Roland Beckmann
Structure of the 80S ribosome-Xrn1 nuclease complex. Nature structural & molecular biology 26 (4) (2019)
Katharina Braunger, Stefan Pfeffer, Shiteshu Shrimal, Reid Gilmore, Otto Berninghausen, Elisabet C Mandon, Thomas A Becker, Friedrich G Förster, Roland Beckmann
Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science (New York, N.Y.) 360 (6385) (2018)
Alexandra G Knorr, Christian Schmidt, Petr Tesina, Otto Berninghausen, Thomas Becker, Birgitta Beatrix, Roland Beckmann
Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation. Nature structural & molecular biology 26 (1) (2018)
Matthias Thoms, Valentin Mitterer, Lukas Kater, Laurent Falquet, Roland Beckmann, Dieter Kressler, Ed Hurt
Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation. Nature communications 9 (1) (2018)
André Heuer, Emma Thomson, Christian Schmidt, Otto Berninghausen, Thomas A Becker, Ed Hurt, Roland Beckmann
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae. eLife 6 (2017)
Jingdong Cheng, Nikola Kellner, Otto Berninghausen, Ed Hurt, Roland Beckmann
3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage. Nature structural & molecular biology 24 (11) (2017)
Anshuk Sarkar, Matthias Thoms, Clara Barrio-Garcia, Emma Thomson, Dirk Flemming, Roland Beckmann, Ed Hurt
Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality control. Nature structural & molecular biology 24 (12) (2017)
Ting Su, Jingdong Cheng, Daniel Sohmen, Rickard Hedman, Otto Berninghausen, Gunnar von Heijne, Daniel N Wilson, Roland Beckmann
The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling. eLife 6 (2017)