Scott D Gray-Owen (Scott Gray-Owen)

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 26

Top Venues

mBio

Nature communications

Communications medicine

Infection and immunity

University of Toronto

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto Nov 01 1998

Canada

Professor :: Department of Molecular Genetics

Publications

Jamie E Fegan, Epshita A Islam, David M Curran, Dixon Ng, Natalie Au, Elissa G Currie, Joseph Zeppa, Jessica Lam, Anthony B Schryvers, Trevor F Moraes, Scott D Gray-Owen
Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae . bioRxiv : the preprint server for biology (2024)
Yu-Hwa Huang, Charles H Yoon, Amit K Gandhi, Thomas Hanley, Carlos Castrillon, Yasuyuki Kondo, Xi Lin, Walter Kim, Chao Yang, Amine Driouchi, Michael C Carroll, Scott D Gray-Owen, Duane R Wesemann, Charles G Drake, Monica M Bertagnolli, Nicole Beauchemin, Richard S Blumberg
High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance. Communications medicine 4 (1) (2024)
Yu-Hwa Huang, Charles H Yoon, Amit K Gandhi, Thomas Hanley, Carlos Castrillon, Yasuyuki Kondo, Xi Lin, Walter Kim, Chao Yang, Amine Driouchi, Michael C Carroll, Scott D Gray-Owen, Duane R Wesemann, Charles G Drake, Monica M Bertagnolli, Nicole Beauchemin, Richard S Blumberg
High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance. Communications medicine 4 (1) (2024)
Isaac S Lee, Jamie E Fegan, Elissa G Currie, Anna Bojagora, Nelly Y Leung, Derrick Rancourt, Muhamed-Kheir Taha, Anthony B Schryvers, Scott D Gray-Owen
Human transferrin and lactoferrin cooperatively support Neisseria meningitidis colonization in the murine nasopharynx. bioRxiv : the preprint server for biology (2024)
Yu-Hwa Huang, Charles H Yoon, Amit K Gandhi, Thomas Hanley, Carlos Castrillon, Yasuyuki Kondo, Xi Lin, Walter Kim, Chao Yang, Amine Driouchi, Michael C Carroll, Scott D Gray-Owen, Duane R Wesemann, Charles G Drake, Monica M Bertagnolli, Nicole Beauchemin, Richard S Blumberg
High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance. Communications medicine 4 (1) (2024)
Hong Yu, Liam J Worrall, Thorsten Berger, Martin Petric, Bryan H Lin, Marija Vuckovic, Craig S Robb, Quan Le, Calem Kenward, Chuanbin Dai, Andrew Wakeham, Shaofeng Liu, Bryan Snow, Chantal Tobin, Patrick Budylowski, Furkan Guvenc, Annick You-Ten, Jillian Haight, Jennifer Silvester, Rashim Pal Singh, Sang Kyun Ahn, Azmiri Sultana, Betty Poon, Jessica Lam, Natasha Christie-Holmes, Mario A Ostrowski, Scott D Gray-Owen, Shawn Kubli, Tak Mak, Natalie C J Strynadka, Robert C Brunham
Identification of an optimized Receptor-Binding Domain Subunit Vaccine against SARS-CoV-2. Journal of immunology (Baltimore, Md. : 1950) (2023)
Epshita A Islam, Jamie E Fegan, Takele A Tefera, David M Curran, Regula C Waeckerlin, Dixon Ng, Sang Kyun Ahn, Chun Heng Royce Lai, Quynh Huong Nguyen, Megha Shah, Liyuwork Tesfaw, Kassaye Adamu, Wubet W Medhin, Abinet Legesse, Getaw Deresse, Belayneh Getachew, Neil Rawlyk, Brock Evans, Andrew Potter, Anthony B Schryvers, Scott D Gray-Owen, Trevor F Moraes
Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida. PLoS pathogens 19 (3) (2023)
George Giorgi Babuadze, Hugues Fausther-Bovendo, Marc-Antoine deLaVega, Brandon Lillie, Maedeh Naghibosadat, Nariman Shahhosseini, Michael A Joyce, Holly A Saffran, D Lorne J Tyrrell, Darryl Falzarano, Chandrika Senthilkumaran, Natasha Christie-Holmes, Steven Ahn, Scott D Gray-Owen, Arinjay Banerjee, Samira Mubareka, Karen Louise Mossman, Chanel Dupont, Jannie Pedersen, Marc-Alexandre Lafrance, Gary P Kobinger, Robert A Kozak
Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters. NPJ vaccines 7 (1) (2022)
Camille Martin-Gallausiaux, Diego Garcia-Weber, Amandine Lashermes, Pierre Larraufie, Ludovica Marinelli, Veronica Teixeira, Alice Rolland, Fabienne Béguet-Crespel, Vincent Brochard, Timothé Quatremare, Alexandre Jamet, Joel Dore, Scott D Gray-Owen, Hervé M Blottière, Cécile Arrieumerlou, Nicolas Lapaque
Akkermansia muciniphila upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway. Gut microbes 14 (1) (2022)
Stacey X Xu, Scott D Gray-Owen
Gonococcal Pelvic Inflammatory Disease: Placing Mechanistic Insights Into the Context of Clinical and Epidemiological Observations. The Journal of infectious diseases 224 (12 Suppl 2) (2022)
Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, Katherine Prieto, Stephanie A Bueler, Sawsan Youssef, Sindy Liao-Chan, Jacob Glanville, Natasha Christie-Holmes, Samira Mubareka, Scott D Gray-Owen, John L Rubinstein, Bebhinn Treanor, Jean-Philippe Julien
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers. Nature communications 12 (1) (2021)
Subha Dahal, Ran Cheng, Peter K Cheung, Terek Been, Ramy Malty, Melissa Geng, Sarah Manianis, Lulzim Shkreta, Shahrazad Jahanshahi, Johanne Toutant, Rose Chan, Sean Park, Mark A Brockman, Mohan Babu, Samira Mubareka, Karen Louise Mossman, Arinjay Banerjee, Scott D Gray-Owen, Martha Brown, Walid A Houry, Benoit Chabot, David Grierson, Alan Cochrane
The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation. Viruses 14 (1) (2021)
Elissa G Currie, Scott D Gray-Owen
Exploring the Ability of Meningococcal Vaccines to Elicit Mucosal Immunity: Insights from Humans and Mice. Pathogens (Basel, Switzerland) 10 (7) (2021)
Thomas J Bateman, Megha Shah, Timothy Pham Ho, Hyejin Esther Shin, Chuxi Pan, Greg Harris, Jamie E Fegan, Epshita A Islam, Sang Kyun Ahn, Yogesh Hooda, Scott D Gray-Owen, Wangxue Chen, Trevor F Moraes
A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature communications 12 (1) (2021)
Ina-Kristin Behrens, Benjamin Busch, Hellen Ishikawa-Ankerhold, Pia Palamides, John E Shively, Cliff Stanners, Carlos Chan, Nelly Leung, Scott D Gray-Owen, Rainer Haas
The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils. mBio 11 (1) (2020)
Baweleta Isho, Kento T Abe, Michelle Zuo, Alainna J Jamal, Bhavisha Rathod, Jenny H Wang, Zhijie Li, Gary Y C Chao, Olga L Rojas, Yeo Myong Bang, Annie Pu, Natasha Christie-Holmes, Christian Gervais, Derek F Ceccarelli, Payman Samavarchi-Tehrani, Furkan Guvenc, Patrick Budylowski, Angel Li, Aimee Paterson, Feng Yun Yue, Lina Maria Marin, Lauren Caldwell, Jeffrey L Wrana, Karen Colwill, Frank Sicheri, Samira Mubareka, Scott D Gray-Owen, Steven J Drews, Walter L Siqueira, Miriam Barrios-Rodiles, Mario A Ostrowski, James M Rini, Yves Durocher, Allison J McGeer, Jennifer L Gommerman, Anne-Claude Gingras
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Science immunology 5 (52) (2020)
Mena Abdel-Nour, Leticia A M Carneiro, Jeffrey Downey, Jessica Tsalikis, Ahmed Outlioua, David Prescott, Leandro Silva Da Costa, Elise S Hovingh, Armin Farahvash, Ryan G Gaudet, Raphael Molinaro, Rob van Dalen, Charles C Y Lau, Farshad C Azimi, Nichole K Escalante, Aaron C Trotman-Grant, Jeffrey E Lee, Scott D Gray-Owen, Maziar Divangahi, Jane-Jane Chen, Dana J Philpott, Damien Arnoult, Stephen E Girardin
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science (New York, N.Y.) 365 (6448) (2020)
Stacey X Xu, Danila Leontyev, Rupert Kaul, Scott D Gray-Owen
Neisseria gonorrhoeae co-infection exacerbates vaginal HIV shedding without affecting systemic viral loads in human CD34+ engrafted mice. PloS one 13 (1) (2018)
Itunuoluwa A Adekoya, Cynthia Xinyi Guo, Scott D Gray-Owen, Andrew D Cox, Janelle Sauvageau
d-Glycero-β-d-Manno-Heptose 1-Phosphate and d-Glycero-β-d-Manno-Heptose 1,7-Biphosphate Are Both Innate Immune Agonists. Journal of immunology (Baltimore, Md. : 1950) 201 (8) (2018)
Teresa R O'Meara, Kwamaa Duah, Cynthia X Guo, Michelle E Maxson, Ryan G Gaudet, Kristy Koselny, Melanie Wellington, Michael E Powers, Jessie MacAlpine, Matthew J O'Meara, Amanda O Veri, Sergio Grinstein, Suzanne M Noble, Damian Krysan, Scott D Gray-Owen, Leah E Cowen
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis. mBio 9 (4) (2018)
Epshita A Islam, Varun C Anipindi, Ian Francis, Yazdan Shaik-Dasthagirisaheb, Stacey Xu, Nelly Leung, Anna Sintsova, Mohsen Amin, Charu Kaushic, Lee M Wetzler, Scott D Gray-Owen
Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract. Infection and immunity 86 (8) (2018)
Johannes B Herrmann, Marcel Muenstermann, Lea Strobel, Alexandra Schubert-Unkmeir, Trent M Woodruff, Scott D Gray-Owen, Andreas Klos, Kay O Johswich
Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment. mBio 9 (1) (2018)
Anna Sintsova, Cynthia X Guo, Helen Sarantis, Tak W Mak, Michael Glogauer, Scott D Gray-Owen
Bcl10 synergistically links CEACAM3 and TLR-dependent inflammatory signalling. Cellular microbiology 20 (1) (2017)
Alevtina Gall, Ryan G Gaudet, Scott D Gray-Owen, Nina R Salama
TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection. mBio 8 (4) (2017)
Yogesh Hooda, Christine Chieh-Lin Lai, Andrew Judd, Carolyn M Buckwalter, Hyejin Esther Shin, Scott D Gray-Owen, Trevor F Moraes
Slam is an outer membrane protein that is required for the surface display of lipidated virulence factors in Neisseria. Nature microbiology 1 (2016)
Ryan G Gaudet, Scott D Gray-Owen
Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity. PLoS pathogens 12 (9) (2016)
Anna Sintsova, Henry Wong, Kelly S MacDonald, Rupert Kaul, Mumtaz Virji, Scott D Gray-Owen
Selection for a CEACAM receptor-specific binding phenotype during Neisseria gonorrhoeae infection of the human genital tract. Infection and immunity 83 (4) (2015)
Charles Calmettes, Christopher Ing, Carolyn M Buckwalter, Majida El Bakkouri, Christine Chieh-Lin Lai, Anastassia Pogoutse, Scott D Gray-Owen, Régis Pomès, Trevor F Moraes
The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD. Nature communications 6 (2015)
Kay O Johswich, Shannon E McCaw, Lea Strobel, Matthias Frosch, Scott D Gray-Owen
Sterilizing immunity elicited by Neisseria meningitidis carriage shows broader protection than predicted by serum antibody cross-reactivity in CEACAM1-humanized mice. Infection and immunity 83 (1) (2014)

Scott D Gray-Owen.css-eqlu8i{font-size:small;padding-left:4px;} (Scott Gray-Owen)

Publication Activity (10 Years)

Top Topics

Top Venues

Scott D Gray-Owen (Scott Gray-Owen)