Sebastian J Hofer

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 23

Top Venues

Nature communications

Nutrients

Nature aging

Autophagy

University of Graz

Karl-Franzens-Universität Graz (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Graz

Austria

Lecturer :: Institute of Molecular Biosciences

Karl-Franzens-Universität Graz

Austria

Student Assistant :: Institute of Molecular Biosciences

Education History

Karl-Franzens-Universität Graz

Austria

PHD :: Institute of Molecular Biosciences

Technische Universität Graz

Austria

MSC

Technische Universität Graz

Austria

BSC

Publications

Sebastian J Hofer, Ioanna Daskalaki, Martina Bergmann, Jasna Friščić, Andreas Zimmermann, Melanie I Mueller, Mahmoud Abdellatif, Raffaele Nicastro, Sarah Masser, Sylvère Durand, Alexander Nartey, Mara Waltenstorfer, Sarah Enzenhofer, Isabella Faimann, Verena Gschiel, Thomas Bajaj, Christine Niemeyer, Ilias Gkikas, Lukas Pein, Giulia Cerrato, Hui Pan, YongTian Liang, Jelena Tadic, Andrea Jerkovic, Fanny Aprahamian, Christine E Robbins, Nitharsshini Nirmalathasan, Hansjörg Habisch, Elisabeth Annerer, Frederik Dethloff, Michael Stumpe, Franziska Grundler, Françoise Wilhelmi de Toledo, Daniel E Heinz, Daniela A Koppold, Anika M Hartmann, Andreas Michalsen, Norbert J Tripolt, Harald Sourij, Thomas R Pieber, Rafael de Cabo, Mark A McCormick, Christoph Magnes, Oliver Kepp, Joern Dengjel, Stephan J Sigrist, Nils Christian Gassen, Simon Sedej, Tobias Madl, Claudio De Virgilio, Ulrich Stelzl, Markus H Hoffmann, Tobias Eisenberg, Nektarios Tavernarakis, Guido Kroemer, Frank Madeo
Spermidine is essential for fasting-mediated autophagy and longevity. Nature cell biology (2024)
Sebastian J Hofer, Ioanna Daskalaki, Mahmoud Abdellatif, Ulrich Stelzl, Simon Sedej, Nektarios Tavernarakis, Guido Kroemer, Frank Madeo
A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity. Autophagy (2024)
Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrián Plaza, Aranzazu Sierra-Ramirez, Manuel Pérez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J Hofer, Christoph Magnes, Frank Madeo, Janet S Duerr, Oscar J Pozo, Maximo-Ibo Galindo, Isabel Del Pino, Riekelt H Houtkooper, Diego Megias, Jose Viña, Marie-Carmen Gomez-Cabrera, Pablo Jose Fernandez-Marcos
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models. Nature communications 14 (1) (2023)
Norbert J Tripolt, Sebastian J Hofer, Peter N Pferschy, Faisal Aziz, Sylvère Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Mara Waltenstorfer, Tobias Eisenberg, Anna M A Obermayer, Regina Riedl, Harald Kojzar, Othmar Moser, Caren Sourij, Heiko Bugger, Abderrahim Oulhaj, Thomas R Pieber, Matthias Zanker, Guido Kroemer, Frank Madeo, Harald Sourij
Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial. Nutrients 15 (3) (2023)
Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrián Plaza, Aranzazu Sierra-Ramirez, Manuel Pérez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J Hofer, Christoph Magnes, Frank Madeo, Janet S Duerr, Oscar J Pozo, Maximo-Ibo Galindo, Isabel Del Pino, Riekelt H Houtkooper, Diego Megias, Jose Viña, Marie-Carmen Gomez-Cabrera, Pablo Jose Fernandez-Marcos
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models. Nature communications 14 (1) (2023)
Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrián Plaza, Aranzazu Sierra-Ramirez, Manuel Pérez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J Hofer, Christoph Magnes, Frank Madeo, Janet S Duerr, Oscar J Pozo, Maximo-Ibo Galindo, Isabel Del Pino, Riekelt H Houtkooper, Diego Megias, Jose Viña, Marie-Carmen Gomez-Cabrera, Pablo Jose Fernandez-Marcos
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models. Nature communications 14 (1) (2023)
Norbert J Tripolt, Sebastian J Hofer, Peter N Pferschy, Faisal Aziz, Sylvère Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Mara Waltenstorfer, Tobias Eisenberg, Anna M A Obermayer, Regina Riedl, Harald Kojzar, Othmar Moser, Caren Sourij, Heiko Bugger, Abderrahim Oulhaj, Thomas R Pieber, Matthias Zanker, Guido Kroemer, Frank Madeo, Harald Sourij
Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial. Nutrients 15 (3) (2023)
Norbert J Tripolt, Sebastian J Hofer, Peter N Pferschy, Faisal Aziz, Sylvère Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Mara Waltenstorfer, Tobias Eisenberg, Anna M A Obermayer, Regina Riedl, Harald Kojzar, Othmar Moser, Caren Sourij, Heiko Bugger, Abderrahim Oulhaj, Thomas R Pieber, Matthias Zanker, Guido Kroemer, Frank Madeo, Harald Sourij
Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial. Nutrients 15 (3) (2023)
Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrián Plaza, Aranzazu Sierra-Ramirez, Manuel Pérez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J Hofer, Christoph Magnes, Frank Madeo, Janet S Duerr, Oscar J Pozo, Maximo-Ibo Galindo, Isabel Del Pino, Riekelt H Houtkooper, Diego Megias, Jose Viña, Marie-Carmen Gomez-Cabrera, Pablo Jose Fernandez-Marcos
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models. Nature communications 14 (1) (2023)
Norbert J Tripolt, Sebastian J Hofer, Peter N Pferschy, Faisal Aziz, Sylvère Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Mara Waltenstorfer, Tobias Eisenberg, Anna M A Obermayer, Regina Riedl, Harald Kojzar, Othmar Moser, Caren Sourij, Heiko Bugger, Abderrahim Oulhaj, Thomas R Pieber, Matthias Zanker, Guido Kroemer, Frank Madeo, Harald Sourij
Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial. Nutrients 15 (3) (2023)
Sebastian J Hofer, Anna Katharina Simon, Martina Bergmann, Tobias Eisenberg, Guido Kroemer, Frank Madeo
Mechanisms of spermidine-induced autophagy and geroprotection. Nature aging 2 (12) (2022)
Sebastian J Hofer, Anna Katharina Simon, Martina Bergmann, Tobias Eisenberg, Guido Kroemer, Frank Madeo
Mechanisms of spermidine-induced autophagy and geroprotection. Nature aging 2 (12) (2022)
Sebastian J Hofer, Anna Katharina Simon, Martina Bergmann, Tobias Eisenberg, Guido Kroemer, Frank Madeo
Mechanisms of spermidine-induced autophagy and geroprotection. Nature aging 2 (12) (2022)
Julia Ring, Jelena Tadic, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunović, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen, Cornelia Sommer, Mirjana Ninkovic, Sandra Seba, Patrick Rockenfeller, Friederike-Nora Vögtle, Joern Dengjel, Chris Meisinger, Adrian Keller, Stephan J Sigrist, Tobias Eisenberg, Frank Madeo
The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity. EMBO molecular medicine 14 (5) (2022)
Mahmoud Abdellatif, Viktoria Trummer-Herbst, Alexander Martin Heberle, Alina Humnig, Tobias Pendl, Sylvère Durand, Giulia Cerrato, Sebastian J Hofer, Moydul Islam, Julia Voglhuber, Jose M Ramos Pittol, Oliver Kepp, Gerald Hoefler, Albrecht Schmidt, Peter P Rainer, Daniel Scherr, Dirk von Lewinski, Egbert Bisping, Julie R McMullen, Abhinav Diwan, Tobias Eisenberg, Frank Madeo, Kathrin Thedieck, Guido Kroemer, Simon Sedej
Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity. Circulation 145 (25) (2022)
Sebastian J Hofer, Anna Katharina Simon, Martina Bergmann, Tobias Eisenberg, Guido Kroemer, Frank Madeo
Mechanisms of spermidine-induced autophagy and geroprotection. Nature aging 2 (12) (2022)
Sebastian J Hofer, YongTian Liang, Andreas Zimmermann, Sabrina Schroeder, Jörn Dengjel, Guido Kroemer, Tobias Eisenberg, Stephan J Sigrist, Frank Madeo
Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging. Autophagy 17 (8) (2021)
Sebastian J Hofer, Didac Carmona-Gutierrez, Melanie I Mueller, Frank Madeo
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application. EMBO molecular medicine (2021)
Mahmoud Abdellatif, Viktoria Trummer-Herbst, Franziska Koser, Sylvère Durand, Rui Adão, Francisco Vasques-Nóvoa, Johanna K Freundt, Julia Voglhuber, Maria-Rosaria Pricolo, Michael Kasa, Clara Türk, Fanny Aprahamian, Elías Herrero-Galán, Sebastian J Hofer, Tobias Pendl, Lavinia Rech, Julia Kargl, Nathaly Anto-Michel, Senka Ljubojevic-Holzer, Julia Schipke, Christina Brandenberger, Martina Auer, Renate Schreiber, Chintan N Koyani, Akos Heinemann, Andreas Zirlik, Albrecht Schmidt, Dirk von Lewinski, Daniel Scherr, Peter P Rainer, Julia von Maltzahn, Christian Mühlfeld, Marcus Krueger, Saša Frank, Frank Madeo, Tobias Eisenberg, Andreas Prokesch, Adelino F Leite-Moreira, André P Lourenço, Jorge Alegre-Cebollada, Stefan Kiechl, Wolfgang A Linke, Guido Kroemer, Simon Sedej
Nicotinamide for the treatment of heart failure with preserved ejection fraction. Science translational medicine 13 (580) (2021)
Guo Chen, Wei Xie, Jihoon Nah, Allan Sauvat, Peng Liu, Federico Pietrocola, Valentina Sica, Didac Carmona-Gutierrez, Andreas Zimmermann, Tobias Pendl, Jelena Tadic, Martina Bergmann, Sebastian J Hofer, Lana Domuz, Sylvie Lachkar, Maria Markaki, Nektarios Tavernarakis, Junichi Sadoshima, Frank Madeo, Oliver Kepp, Guido Kroemer
3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO molecular medicine 11 (11) (2019)
Marta Maglione, Gaga Kochlamazashvili, Tobias Eisenberg, Bence Rácz, Eva Michael, David Toppe, Alexander Stumpf, Alexander Wirth, Andre Zeug, Franziska E Müller, Laura Moreno-Velasquez, Rosanna P Sammons, Sebastian J Hofer, Frank Madeo, Tanja Maritzen, Nikolaus Maier, Evgeni G Ponimaskin, Dietmar Schmitz, Volker Haucke, Stephan J Sigrist
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses. Scientific reports 9 (1) (2019)
Andreas Zimmermann, Katharina Kainz, Sebastian J Hofer, Maria A Bauer, Sabrina Schroeder, Jörn Dengjel, Federico Pietrocola, Oliver Kepp, Christoph Ruckenstuhl, Tobias Eisenberg, Stephan J Sigrist, Frank Madeo, Didac Carmona-Gutierrez, Guido Kroemer
4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects. Autophagy 15 (9) (2019)
Didac Carmona-Gutierrez, Andreas Zimmermann, Katharina Kainz, Federico Pietrocola, Guo Chen, Silvia Maglioni, Alfonso Schiavi, Jihoon Nah, Sara Mertel, Christine B Beuschel, Francesca Castoldi, Valentina Sica, Gert Trausinger, Reingard Raml, Cornelia Sommer, Sabrina Schroeder, Sebastian J Hofer, Maria A Bauer, Tobias Pendl, Jelena Tadic, Christopher Dammbrueck, Zehan Hu, Christoph Ruckenstuhl, Tobias Eisenberg, Sylvere Durand, Noélie Bossut, Fanny Aprahamian, Mahmoud Abdellatif, Simon Sedej, David P Enot, Heimo Wolinski, Joern Dengjel, Oliver Kepp, Christoph Magnes, Frank Sinner, Thomas R Pieber, Junichi Sadoshima, Natascia Ventura, Stephan J Sigrist, Guido Kroemer, Frank Madeo
The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species. Nature communications 10 (1) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Sebastian J Hofer