Seth B Herzon

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 59

Top Topics

Mass Spectrometry

Top Venues

Journal of the American Chemical Society

The Journal of organic chemistry

Science (New York, N.Y.)

Nature chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Eric D Huseman, Anna Lo, Olga Fedorova, James L Elia, Susan E Gueble, Kingson Lin, Ranjini K Sundaram, Joonseok Oh, Jinchan Liu, Fabian S Menges, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Victor S Batista, Jason M Crawford, Anna Marie Pyle, Ranjit S Bindra, Seth B Herzon
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal of the American Chemical Society (2024)
Brandon W Alexander, Noah M Bartfield, Vaani Gupta, Brandon Q Mercado, Mark Del Campo, Seth B Herzon
An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloids. Science (New York, N.Y.) 383 (6685) (2024)
Eric D Huseman, Anna Lo, Olga Fedorova, James L Elia, Susan E Gueble, Kingson Lin, Ranjini K Sundaram, Joonseok Oh, Jinchan Liu, Fabian S Menges, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Victor S Batista, Jason M Crawford, Anna Marie Pyle, Ranjit S Bindra, Seth B Herzon
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal of the American Chemical Society (2024)
Eric D Huseman, Anna Lo, Olga Fedorova, James L Elia, Susan E Gueble, Kingson Lin, Ranjini K Sundaram, Joonseok Oh, Jinchan Liu, Fabian S Menges, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Victor S Batista, Jason M Crawford, Anna Marie Pyle, Ranjit S Bindra, Seth B Herzon
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal of the American Chemical Society 146 (27) (2024)
Brandon W Alexander, Noah M Bartfield, Vaani Gupta, Brandon Q Mercado, Mark Del Campo, Seth B Herzon
An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloids. Science (New York, N.Y.) 383 (6685) (2024)
Brandon W Alexander, Noah M Bartfield, Vaani Gupta, Brandon Q Mercado, Mark Del Campo, Seth B Herzon
An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloids. Science (New York, N.Y.) 383 (6685) (2024)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry 88 (4) (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry 88 (4) (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry 88 (4) (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry 88 (4) (2023)
Zhi Xu, Xin Li, John A Rose, Seth B Herzon
Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers. Natural product reports (2023)
Madeline C Frischling, Seth B Herzon
On the Abundance and Stability of Diazo-Containing Secondary Metabolites: Enantioselective Synthesis of (-)-Nenestatin A. Organic letters (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry (2023)
Mikaela DiBello, Alan R Healy, Herman Nikolayevskiy, Zhi Xu, Seth B Herzon
Structure Elucidation of Secondary Metabolites: Current Frontiers and Lingering Pitfalls. Accounts of chemical research (2023)
Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Approach to Diaporthein B. The Journal of organic chemistry (2023)
Olivia Goethe, Mikaela DiBello, Seth B Herzon
Total synthesis of structurally diverse pleuromutilin antibiotics. Nature chemistry 14 (11) (2022)
Zhi Xu, Mikaela DiBello, Zechun Wang, John A Rose, Lei Chen, Xin Li, Seth B Herzon
Stereocontrolled Synthesis of the Fully Glycosylated Monomeric Unit of Lomaiviticin A. Journal of the American Chemical Society 144 (35) (2022)
Kingson Lin, Susan E Gueble, Ranjini K Sundaram, Eric D Huseman, Ranjit S Bindra, Seth B Herzon
Mechanism-based design of agents that selectively target drug-resistant glioma. Science (New York, N.Y.) 377 (6605) (2022)
Yiyun Cao, Joonseok Oh, Mengzhao Xue, Won Jae Huh, Jiawei Wang, Jaime A Gonzalez-Hernandez, Tyler A Rice, Anjelica L Martin, Deguang Song, Jason M Crawford, Seth B Herzon, Noah W Palm
Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites. Science (New York, N.Y.) 378 (6618) (2022)
Olivia Goethe, Mikaela DiBello, Seth B Herzon
Author Correction: Total synthesis of structurally diverse pleuromutilin antibiotics. Nature chemistry (2022)
Kevin M Hoang, Xiaoying Zheng, Seth B Herzon
Synthesis of 2-Deoxyglycosides Bearing Free Hydroxyl Substituents on the Glycosyl Donor. The Journal of organic chemistry 87 (16) (2022)
Kevin M Hoang, Nicholas R Lees, Seth B Herzon
General Method for the Synthesis of α- or β-Deoxyaminoglycosides Bearing Basic Nitrogen. Journal of the American Chemical Society 143 (7) (2021)
Miho Kaneko, Zhenwu Li, Matthew Burk, Laureen Colis, Seth B Herzon
Synthesis and Biological Evaluation of (2S,2'S)-Lomaiviticin A. Journal of the American Chemical Society 143 (2) (2021)
Jason M Crawford, Gong-Li Tang, Seth B Herzon
Natural Products: An Era of Discovery in Organic Chemistry. The Journal of organic chemistry 86 (16) (2021)
Peyton C Williams, Kevin M Wernke, Alina Tirla, Seth B Herzon
Employing chemical synthesis to study the structure and function of colibactin, a "dark matter" metabolite. Natural product reports 37 (11) (2021)
Lee Joon Kim, Mengzhao Xue, Xin Li, Zhi Xu, Eric Paulson, Brandon Mercado, Hosea M Nelson, Seth B Herzon
Structure Revision of the Lomaiviticins. Journal of the American Chemical Society 143 (17) (2021)
Daniel Abegg, Martin Tomanik, Nan Qiu, Dany Pechalrieu, Anton Shuster, Bruno Commare, Antonio Togni, Seth B Herzon, Alexander Adibekian
Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. Journal of the American Chemical Society 143 (48) (2021)
Martin Tomanik, Zhi Xu, Seth B Herzon
Enantioselective Synthesis of Euonyminol. Journal of the American Chemical Society 143 (2) (2021)
Ian Tingyung Hsu, Martin Tomanik, Seth B Herzon
Metric-Based Analysis of Convergence in Complex Molecule Synthesis. Accounts of chemical research 54 (4) (2021)
Alina Tirla, Kevin M Wernke, Seth B Herzon
On the Stability and Spectroscopic Properties of 5-Hydroxyoxazole-4-carboxylic Acid Derivatives. Organic letters 23 (14) (2021)
Martin Tomanik, Zhi Xu, Facheng Guo, Zechun Wang, Ke R Yang, Victor S Batista, Seth B Herzon
Development of an Enantioselective Synthesis of (-)-Euonyminol. The Journal of organic chemistry 86 (23) (2021)
Kevin M Wernke, Alina Tirla, Mengzhao Xue, Yulia V Surovtseva, Fabian S Menges, Seth B Herzon
Probing Microbiome Genotoxicity: A Stable Colibactin Provides Insight into Structure-Activity Relationships and Facilitates Mechanism of Action Studies. Journal of the American Chemical Society 143 (38) (2021)
Martin Tomanik, Ian Tingyung Hsu, Seth B Herzon
Fragment Coupling Reactions in Total Synthesis That Form Carbon-Carbon Bonds via Carbanionic or Free Radical Intermediates. Angewandte Chemie (International ed. in English) 60 (3) (2020)
Mengzhao Xue, Kevin M Wernke, Seth B Herzon
Depurination of Colibactin-Derived Interstrand Cross-Links. Biochemistry 59 (7) (2020)
Martin Tomanik, Christos Economou, Madeline C Frischling, Mengzhao Xue, Victoria A Marks, Brandon Q Mercado, Seth B Herzon
Development of a Convergent Enantioselective Synthetic Route to (-)-Myrocin G. The Journal of organic chemistry 85 (14) (2020)
Seth B Herzon
Macrocyclic colibactins. Nature chemistry 12 (11) (2020)
John A Rose, Subham Mahapatra, Xin Li, Chao Wang, Lei Chen, Steven M Swick, Seth B Herzon
Synthesis of the bis(cyclohexenone) core of (-)-lomaiviticin A. Chemical science 11 (28) (2020)
Kevin M Hoang, Nicholas R Lees, Seth B Herzon
Programmable Synthesis of 2-Deoxyglycosides. Journal of the American Chemical Society 141 (20) (2019)
Seth B Herzon, Christopher D Vanderwal
Introduction: Natural Product Synthesis. Chemical reviews 117 (18) (2019)
Mengzhao Xue, Chung Sub Kim, Alan R Healy, Kevin M Wernke, Zhixun Wang, Madeline C Frischling, Emilee E Shine, Weiwei Wang, Seth B Herzon, Jason M Crawford
Structure elucidation of colibactin and its DNA cross-links. Science (New York, N.Y.) 365 (6457) (2019)
Alan R Healy, Kevin M Wernke, Chung Sub Kim, Nicholas R Lees, Jason M Crawford, Seth B Herzon
Synthesis and reactivity of precolibactin 886. Nature chemistry 11 (10) (2019)
Olivia Goethe, Abigail Heuer, Xiaoshen Ma, Zhixun Wang, Seth B Herzon
Antibacterial properties and clinical potential of pleuromutilins. Natural product reports 36 (1) (2018)
Christos Economou, Martin Tomanik, Seth B Herzon
Synthesis of Myrocin G, the Putative Active Form of the Myrocin Antitumor Antibiotics. Journal of the American Chemical Society 140 (47) (2018)
Xiaoshen Ma, Roman Kucera, Olivia F Goethe, Stephen K Murphy, Seth B Herzon
Directed C-H Bond Oxidation of (+)-Pleuromutilin. The Journal of organic chemistry 83 (13) (2018)
Seth B Herzon
DNA Repair: Unconventional Lesions Require Unconventional Repair. Biochemistry 57 (7) (2018)
Mengzhao Xue, Emilee E Shine, Weiwei Wang, Jason M Crawford, Seth B Herzon
Characterization of Natural Colibactin-Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening. Biochemistry 57 (45) (2018)
Emilee E Shine, Mengzhao Xue, Jaymin R Patel, Alan R Healy, Yulia V Surovtseva, Seth B Herzon, Jason M Crawford
Model Colibactins Exhibit Human Cell Genotoxicity in the Absence of Host Bacteria. ACS chemical biology 13 (12) (2018)
Stephen K Murphy, Mingshuo Zeng, Seth B Herzon
A modular and enantioselective synthesis of the pleuromutilin antibiotics. Science (New York, N.Y.) 356 (6341) (2018)
Xiaoshen Ma, Seth B Herzon
Cobalt bis(acetylacetonate)-tert-butyl hydroperoxide-triethylsilane: a general reagent combination for the Markovnikov-selective hydrofunctionalization of alkenes by hydrogen atom transfer. Beilstein journal of organic chemistry 14 (2018)
Mingshuo Zeng, Stephen K Murphy, Seth B Herzon
Development of a Modular Synthetic Route to (+)-Pleuromutilin, (+)-12-epi-Mutilins, and Related Structures. Journal of the American Chemical Society 139 (45) (2017)
Xiaoshen Ma, Hester Dang, John A Rose, Paul Rablen, Seth B Herzon
Hydroheteroarylation of Unactivated Alkenes Using N-Methoxyheteroarenium Salts. Journal of the American Chemical Society 139 (16) (2017)
Prabhanshu Tripathi, Emilee E Shine, Alan R Healy, Chung Sub Kim, Seth B Herzon, Steven D Bruner, Jason M Crawford
ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance. Journal of the American Chemical Society 139 (49) (2017)
Alan R Healy, Seth B Herzon
Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective. Journal of the American Chemical Society 139 (42) (2017)
Naga Sandhya Guntaka, Alan R Healy, Jason M Crawford, Seth B Herzon, Steven D Bruner
Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway. ACS chemical biology 12 (10) (2017)
Herman Nikolayevskiy, Maung Kyaw Moe Tun, Paul R Rablen, Choukri Ben Mamoun, Seth B Herzon
A complex stereochemical relay approach to the antimalarial alkaloid ocimicide A1. Evidence for a structural revision. Chemical science 8 (7) (2017)
Stephen K Murphy, Mingshuo Zeng, Seth B Herzon
Scalable Synthesis of a Key Intermediate for the Production of Pleuromutilin-Based Antibiotics. Organic letters 19 (18) (2017)
Seth B Herzon
The Mechanism of Action of (-)-Lomaiviticin A. Accounts of chemical research 50 (10) (2017)
Eric P Trautman, Alan R Healy, Emilee E Shine, Seth B Herzon, Jason M Crawford
Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis. Journal of the American Chemical Society 139 (11) (2017)