Xiaoshen Ma

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 17

Top Venues

The Journal of organic chemistry

Organic letters

Journal of medicinal chemistry

Journal of the American Chemical Society

Merck Research Laboratories Boston

Yale University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Merck Research Laboratories Boston Jul 02 2018

United States

Senior Scientist :: Discovery Chemistry

Education History

Yale University

United States

PHD :: Chemistry

Peking University

China

BSC :: College of Chemistry and Molecular Engineering

Publications

Xiaoshen Ma, Joanna L Chen, Bryce E Gaskins
Decarboxylative C-N Coupling of 2,2-Difluorobicyclo[1.1.1]pentane (BCP-F 2 ) Building Blocks. Organic letters (2024)
Xiaoshen Ma, David L Sloman, Ruchia Duggal, Kenneth D Anderson, Jeanine E Ballard, Indu Bharathan, Christopher Brynczka, Symon Gathiaka, Timothy J Henderson, Thomas W Lyons, Richard Miller, Erik V Munsell, Peter Orth, Ryan D Otte, Anandan Palani, Danica A Rankic, Michelle R Robinson, Aaron C Sather, Nicolas Solban, Xuelei Sherry Song, Xin Wen, Zangwei Xu, Yi Yang, Ruojing Yang, Phil J Day, Alexander Stoeck, David Jonathan Bennett, Yongxin Han
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor. Journal of medicinal chemistry 67 (13) (2024)
Xiaoshen Ma, Adam M Beard, Samantha A Burgess, Miroslawa Darlak, Justin A Newman, Lisa M Nogle, Mark J Pietrafitta, David A Smith, Xiao Wang, Lei Yue
General Synthesis of Conformationally Constrained Noncanonical Amino Acids with C( sp 3 )-Rich Benzene Bioisosteres. The Journal of organic chemistry 89 (7) (2024)
Xiaoshen Ma, David L Sloman, Ruchia Duggal, Kenneth D Anderson, Jeanine E Ballard, Indu Bharathan, Christopher Brynczka, Symon Gathiaka, Timothy J Henderson, Thomas W Lyons, Richard Miller, Erik V Munsell, Peter Orth, Ryan D Otte, Anandan Palani, Danica A Rankic, Michelle R Robinson, Aaron C Sather, Nicolas Solban, Xuelei Sherry Song, Xin Wen, Zangwei Xu, Yi Yang, Ruojing Yang, Phil J Day, Alexander Stoeck, David Jonathan Bennett, Yongxin Han
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor. Journal of medicinal chemistry 67 (13) (2024)
Xiaoshen Ma, Adam M Beard, Samantha A Burgess, Miroslawa Darlak, Justin A Newman, Lisa M Nogle, Mark J Pietrafitta, David A Smith, Xiao Wang, Lei Yue
General Synthesis of Conformationally Constrained Noncanonical Amino Acids with C( sp 3 )-Rich Benzene Bioisosteres. The Journal of organic chemistry (2024)
Xiaoshen Ma, Adam M Beard, Samantha A Burgess, Miroslawa Darlak, Justin A Newman, Lisa M Nogle, Mark J Pietrafitta, David A Smith, Xiao Wang, Lei Yue
General Synthesis of Conformationally Constrained Noncanonical Amino Acids with C( sp 3 )-Rich Benzene Bioisosteres. The Journal of organic chemistry 89 (7) (2024)
Xiaoshen Ma, Joanna L Chen, Bryce E Gaskins
Decarboxylative C-N Coupling of 2,2-Difluorobicyclo[1.1.1]pentane (BCP-F 2 ) Building Blocks. Organic letters 26 (9) (2024)
Xiaoshen Ma, David L Sloman, Ruchia Duggal, Kenneth D Anderson, Jeanine E Ballard, Indu Bharathan, Christopher Brynczka, Symon Gathiaka, Timothy J Henderson, Thomas W Lyons, Richard Miller, Erik V Munsell, Peter Orth, Ryan D Otte, Anandan Palani, Danica A Rankic, Michelle R Robinson, Aaron C Sather, Nicolas Solban, Xuelei Sherry Song, Xin Wen, Zangwei Xu, Yi Yang, Ruojing Yang, Phil J Day, Alexander Stoeck, David Jonathan Bennett, Yongxin Han
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor. Journal of medicinal chemistry (2024)
Olivia L Garry, Michael Heilmann, Jingjia Chen, Yufan Liang, Xiaheng Zhang, Xiaoshen Ma, Charles S Yeung, David Jonathan Bennett, David W C MacMillan
Rapid Access to 2-Substituted Bicyclo[1.1.1]pentanes. Journal of the American Chemical Society (2023)
Xiaoshen Ma, Yuan Jiang
Synthesis of gem -Diboromethyl-Substituted Bicyclo[1.1.1]pentanes and Their Application in Palladium-Catalyzed Cross Couplings. The Journal of organic chemistry (2023)
Olivia L Garry, Michael Heilmann, Jingjia Chen, Yufan Liang, Xiaheng Zhang, Xiaoshen Ma, Charles S Yeung, David Jonathan Bennett, David W C MacMillan
Rapid Access to 2-Substituted Bicyclo[1.1.1]pentanes. Journal of the American Chemical Society 145 (5) (2023)
Xiaoshen Ma, Yuan Jiang
Synthesis of gem -Diboromethyl-Substituted Bicyclo[1.1.1]pentanes and Their Application in Palladium-Catalyzed Cross Couplings. The Journal of organic chemistry 88 (3) (2023)
Xiaoshen Ma, Charles S Yeung
Achieving C(sp2)-C(sp3) Coupling with BCP-F2 Building Blocks via Barluenga Coupling: A Comparative Approach. The Journal of organic chemistry 86 (15) (2021)
Xiaoshen Ma, Yongxin Han, David J Bennett
Selective Synthesis of 1-Dialkylamino-2-alkylbicyclo-[1.1.1]pentanes. Organic letters 22 (22) (2020)
Xiaoshen Ma, David L Sloman, Yongxin Han, David J Bennett
A Selective Synthesis of 2,2-Difluorobicyclo[1.1.1]pentane Analogues: "BCP-F2". Organic letters 21 (18) (2019)
Olivia Goethe, Abigail Heuer, Xiaoshen Ma, Zhixun Wang, Seth B Herzon
Antibacterial properties and clinical potential of pleuromutilins. Natural product reports 36 (1) (2018)
Xiaoshen Ma, Seth B Herzon
Cobalt bis(acetylacetonate)-tert-butyl hydroperoxide-triethylsilane: a general reagent combination for the Markovnikov-selective hydrofunctionalization of alkenes by hydrogen atom transfer. Beilstein journal of organic chemistry 14 (2018)

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Publication Activity (10 Years)

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Xiaoshen Ma