Alexander Adibekian

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 31

Top Topics

Binding Protein

Breast Cancer Cells

Vascular Endothelial Growth Factor

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Journal of the American Chemical Society

Chemical research in toxicology

ACS chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Nan Qiu, Dany Pechalrieu, Daniel Abegg, Alexander Adibekian
Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity. Chemical research in toxicology (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Nan Qiu, Dany Pechalrieu, Daniel Abegg, Alexander Adibekian
Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity. Chemical research in toxicology 37 (4) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Yuquan Tong, Peiyuan Zhang, Xueyi Yang, Xiaohui Liu, Jie Zhang, Magda Grudniewska, Ikrak Jung, Daniel Abegg, Jun Liu, Jessica L Childs-Disney, Quentin M R Gibaut, Hafeez S Haniff, Alexander Adibekian, M Maral Mouradian, Matthew D Disney
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Nan Qiu, Dany Pechalrieu, Daniel Abegg, Alexander Adibekian
Chemoproteomic Profiling Maps Zinc-Dependent Cysteine Reactivity. Chemical research in toxicology 37 (4) (2024)
Yuquan Tong, Yeongju Lee, Xiaohui Liu, Jessica L Childs-Disney, Blessy M Suresh, Raphael I Benhamou, Chunying Yang, Weimin Li, Matthew G Costales, Hafeez S Haniff, Sonja Sievers, Daniel Abegg, Tristan Wegner, Tiffany O Paulisch, Elizabeth Lekah, Maison Grefe, Gogce Crynen, Montina Van Meter, Tenghui Wang, Quentin M R Gibaut, John L Cleveland, Alexander Adibekian, Frank Glorius, Herbert Waldmann, Matthew D Disney
Programming inactive RNA-binding small molecules into bioactive degraders. Nature (2023)
Yuquan Tong, Quentin M R Gibaut, Warren Rouse, Jessica L Childs-Disney, Blessy M Suresh, Daniel Abegg, Shruti Choudhary, Yoshihiro Akahori, Alexander Adibekian, Walter N Moss, Matthew D Disney
Correction to "Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA". Journal of the American Chemical Society (2023)
Blessy M Suresh, Yuquan Tong, Daniel Abegg, Alexander Adibekian, Jessica L Childs-Disney, Matthew D Disney
Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular Selectivity. ACS chemical biology (2023)
Yuquan Tong, Quentin M R Gibaut, Warren Rouse, Jessica L Childs-Disney, Blessy M Suresh, Daniel Abegg, Shruti Choudhary, Yoshihiro Akahori, Alexander Adibekian, Walter N Moss, Matthew D Disney
Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA . Journal of the American Chemical Society 144 (26) (2022)
Fei Ye, Hafeez S Haniff, Blessy M Suresh, Dong Yang, Peiyuan Zhang, Gogce Crynen, Christiana N Teijaro, Wei Yan, Daniel Abegg, Alexander Adibekian, Ben Shen, Matthew D Disney
Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA. ACS chemical biology 17 (2) (2022)
Samantha M Meyer, Toru Tanaka, Patrick R A Zanon, Jared T Baisden, Daniel Abegg, Xueyi Yang, Yoshihiro Akahori, Zainab Alshakarchi, Michael D Cameron, Alexander Adibekian, Matthew D Disney
DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC). Journal of the American Chemical Society 144 (46) (2022)
Raphael I Benhamou, Blessy M Suresh, Yuquan Tong, Wesley G Cochrane, Valerie Cavett, Simon Vezina-Dawod, Daniel Abegg, Jessica L Childs-Disney, Alexander Adibekian, Brian M Paegel, Matthew D Disney
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor. Proceedings of the National Academy of Sciences of the United States of America 119 (6) (2022)
Peiyuan Zhang, Xiaohui Liu, Daniel Abegg, Toru Tanaka, Yuquan Tong, Raphael I Benhamou, Jared T Baisden, Gogce Crynen, Samantha M Meyer, Michael D Cameron, Arnab K Chatterjee, Alexander Adibekian, Jessica L Childs-Disney, Matthew D Disney
Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. Journal of the American Chemical Society 143 (33) (2021)
Anton Shuster, Dany Pechalrieu, Cody B Jackson, Daniel Abegg, Hyeryun Choe, Alexander Adibekian
Clinical Antiviral Drug Arbidol Inhibits Infection by SARS-CoV-2 and Variants through Direct Binding to the Spike Protein. ACS chemical biology (2021)
Daniel Abegg, Martin Tomanik, Nan Qiu, Dany Pechalrieu, Anton Shuster, Bruno Commare, Antonio Togni, Seth B Herzon, Alexander Adibekian
Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. Journal of the American Chemical Society 143 (48) (2021)
Chengsen Cui, Brendan G Dwyer, Chang Liu, Daniel Abegg, Zhong-Jian Cai, Dominic G Hoch, Xianglin Yin, Nan Qiu, Jie-Qing Liu, Alexander Adibekian, Mingji Dai
Total Synthesis and Target Identification of the Curcusone Diterpenes. Journal of the American Chemical Society 143 (11) (2021)
Xiaohui Liu, Hafeez S Haniff, Jessica L Childs-Disney, Anton Shuster, Haruo Aikawa, Alexander Adibekian, Matthew D Disney
Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands. Journal of the American Chemical Society 142 (15) (2020)
Brendan G Dwyer, Chao Wang, Daniel Abegg, Brittney Racioppo, Nan Qiu, Zhensheng Zhao, Dany Pechalrieu, Anton Shuster, Dominic G Hoch, Alexander Adibekian
Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism. Angewandte Chemie (International ed. in English) 60 (6) (2020)
Hafeez S Haniff, Laurent Knerr, Xiaohui Liu, Gogce Crynen, Jonas Boström, Daniel Abegg, Alexander Adibekian, Elizabeth Lekah, Kye Won Wang, Michael D Cameron, Ilyas Yildirim, Malin Lemurell, Matthew D Disney
Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions. Nature chemistry 12 (10) (2020)
Matthew G Costales, Dominic G Hoch, Daniel Abegg, Jessica L Childs-Disney, Sai Pradeep Velagapudi, Alexander Adibekian, Matthew D Disney
A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin. Journal of the American Chemical Society 141 (7) (2019)
J Thomas Hannich, A Galih Haribowo, Sébastien Gentina, Melanie Paillard, Ludovic Gomez, Bruno Pillot, Hélène Thibault, Daniel Abegg, Nicolas Guex, Andreas Zumbuehl, Alexander Adibekian, Michel Ovize, Jean-Claude Martinou, Howard Riezman
1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding. Nature metabolism 1 (10) (2019)
Chao Wang, Daniel Abegg, Brendan G Dwyer, Alexander Adibekian
Discovery and Evaluation of New Activity-Based Probes for Serine Hydrolases. Chembiochem : a European journal of chemical biology 20 (17) (2019)
Dexter C Davis, Dominic G Hoch, Li Wu, Daniel Abegg, Brandon S Martin, Zhong-Yin Zhang, Alexander Adibekian, Mingji Dai
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids. Journal of the American Chemical Society 140 (50) (2018)
Daniel Abegg, Giulio Gasparini, Dominic G Hoch, Anton Shuster, Eline Bartolami, Stefan Matile, Alexander Adibekian
Strained Cyclic Disulfides Enable Cellular Uptake by Reacting with the Transferrin Receptor. Journal of the American Chemical Society 139 (1) (2016)