Shane W Krska (Shane Krska)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 27

Top Venues

Journal of the American Chemical Society

Bioconjugate chemistry

Accounts of chemical research

Science (New York, N.Y.)

Merck

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Merck Jan 01 2015

United States

Senior Principal Scientist :: Discovery Automation & Capabilities Enhancement

Merck Aug 01 2012 - Dec 31 2014

United States

Principal Scientist :: Discovery Chemistry

Merck Jan 01 2007 - Jul 01 2012

United States

Senior Investigator :: Process Chemistry

Merck Oct 01 2002 - Dec 31 2006

United States

Research Fellow :: Process Chemistry

Merck Aug 05 1999 - Oct 01 2002

United States

Senior Research Chemist :: Chemical Engineering R&D

University of California, Berkeley Aug 01 1997 - Jun 01 1999

United States

Postdoctoral Research Associate :: Chemistry

Education History

Massachusetts Institute of Technology Sep 01 1992 - Jun 01 1997

United States

PHD :: Chemistry

South Dakota School of Mines and Technology Sep 01 1988 - Jun 01 1992

United States

BSC :: Chemistry

Publications

E William Webb, Kevin Cheng, Wade P Winton, Brandon J C Klein, Gregory David Bowden, Mami Horikawa, S Wendy Liu, Jay S Wright, Stefan Verhoog, Dipannita Kalyani, Michael Wismer, Shane W Krska, Melanie S Sanford, Peter J H Scott
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration. Journal of the American Chemical Society (2024)
E William Webb, Kevin Cheng, Wade P Winton, Brandon J C Klein, Gregory David Bowden, Mami Horikawa, S Wendy Liu, Jay S Wright, Stefan Verhoog, Dipannita Kalyani, Michael Wismer, Shane W Krska, Melanie S Sanford, Peter J H Scott
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration. Journal of the American Chemical Society 146 (15) (2024)
E William Webb, Kevin Cheng, Wade P Winton, Brandon J C Klein, Gregory David Bowden, Mami Horikawa, S Wendy Liu, Jay S Wright, Stefan Verhoog, Dipannita Kalyani, Michael Wismer, Shane W Krska, Melanie S Sanford, Peter J H Scott
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration. Journal of the American Chemical Society 146 (15) (2024)
E William Webb, Kevin Cheng, Wade P Winton, Brandon J C Klein, Gregory David Bowden, Mami Horikawa, S Wendy Liu, Jay S Wright, Stefan Verhoog, Dipannita Kalyani, Michael Wismer, Shane W Krska, Melanie S Sanford, Peter J H Scott
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration. Journal of the American Chemical Society 146 (15) (2024)
E William Webb, Kevin Cheng, Wade P Winton, Brandon J C Klein, Gregory David Bowden, Mami Horikawa, S Wendy Liu, Jay S Wright, Stefan Verhoog, Dipannita Kalyani, Michael Wismer, Shane W Krska, Melanie S Sanford, Peter J H Scott
Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration. Journal of the American Chemical Society 146 (15) (2024)
Rachel K Chambers, Jacob D Weaver, Jinho Kim, Jason L Hoar, Shane W Krska, M Christina White
A preparative small-molecule mimic of liver CYP450 enzymes in the aliphatic C-H oxidation of carbocyclic N -heterocycles. Proceedings of the National Academy of Sciences of the United States of America 120 (29) (2023)
Soham Maity, Marco A Lopez, Desiree M Bates, Shishi Lin, Shane W Krska, Shannon S Stahl
Polar Heterobenzylic C(sp 3 )-H Chlorination Pathway Enabling Efficient Diversification of Aromatic Nitrogen Heterocycles. Journal of the American Chemical Society (2023)
Wendy Cao, Johnathan C Maza, Natalia Chernyak, John A Flygare, Shane W Krska, F Dean Toste, Matthew B Francis
Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate chemistry (2023)
Wendy Cao, Johnathan C Maza, Natalia Chernyak, John A Flygare, Shane W Krska, F Dean Toste, Matthew B Francis
Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate chemistry 34 (3) (2023)
Wendy Cao, Johnathan C Maza, Natalia Chernyak, John A Flygare, Shane W Krska, F Dean Toste, Matthew B Francis
Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate chemistry 34 (3) (2023)
Wendy Cao, Johnathan C Maza, Natalia Chernyak, John A Flygare, Shane W Krska, F Dean Toste, Matthew B Francis
Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions. Bioconjugate chemistry 34 (3) (2023)
Si-Jie Chen, Shane W Krska, Shannon S Stahl
Copper-Catalyzed Benzylic C-H Cross-Coupling Enabled by Redox Buffers: Expanding Synthetic Access to Three-Dimensional Chemical Space. Accounts of chemical research (2023)
Cesar N Prieto Kullmer, Jacob A Kautzky, Shane W Krska, Timothy Nowak, Spencer D Dreher, David W C MacMillan
Accelerating reaction generality and mechanistic insight through additive mapping. Science (New York, N.Y.) 376 (6592) (2022)
Spencer D Dreher, Shane W Krska
Chemistry Informer Libraries: Conception, Early Experience, and Role in the Future of Cheminformatics. Accounts of chemical research 54 (7) (2021)
Ryan P King, Shane W Krska, Stephen L Buchwald
A Neophyl Palladacycle as an Air- and Thermally Stable Precursor to Oxidative Addition Complexes. Organic letters 23 (20) (2021)
Ryan P King, Shane W Krska, Stephen L Buchwald
A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes. Organic letters 23 (15) (2021)
Aristidis Vasilopoulos, Shane W Krska, Shannon S Stahl
C(sp3)-H methylation enabled by peroxide photosensitization and Ni-mediated radical coupling. Science (New York, N.Y.) 372 (6540) (2021)
Sung-Eun Suh, Leah E Nkulu, Shishi Lin, Shane W Krska, Shannon S Stahl
Benzylic C-H isocyanation/amine coupling sequence enabling high-throughput synthesis of pharmaceutically relevant ureas. Chemical science 12 (30) (2021)
Si-Jie Chen, Dung L Golden, Shane W Krska, Shannon S Stahl
Copper-Catalyzed Cross-Coupling of Benzylic C-H Bonds and Azoles with Controlled N-Site Selectivity. Journal of the American Chemical Society 143 (36) (2021)
Karl B Hansen, Yi Hsiao, Feng Xu, Nelo R Rivera, Andrew Clausen, Michele Kubryk, Shane W Krska, Thorsten Rosner, Bryon Simmons, Jaume Balsells, Nori Ikemoto, Yongkui Sun, Felix Spindler, Christophe Malan, Edward J J Grabowski, Joseph D Armstrong
Correction to "Highly Efficient Asymmetric Synthesis of Sitagliptin". Journal of the American Chemical Society 142 (31) (2020)
Johnathan C Maza, Alexandra V Ramsey, Meire Mehare, Shane W Krska, Craig A Parish, Matthew B Francis
Secondary modification of oxidatively-modified proline N-termini for the construction of complex bioconjugates. Organic & biomolecular chemistry 18 (10) (2020)
Alex J Chinn, Jaeyeon Hwang, Byoungmoo Kim, Craig A Parish, Shane W Krska, Scott J Miller
Application of High-Throughput Competition Experiments in the Development of Aspartate-Directed Site-Selective Modification of Tyrosine Residues in Peptides. The Journal of organic chemistry 85 (14) (2020)
Mycah R Uehling, Ryan P King, Shane W Krska, Tim Cernak, Stephen L Buchwald
Pharmaceutical diversification via palladium oxidative addition complexes. Science (New York, N.Y.) 363 (6425) (2019)
Johnathan C Maza, Daniel L V Bader, Lifeng Xiao, Alan M Marmelstein, Daniel D Brauer, Adel M ElSohly, Matthew J Smith, Shane W Krska, Craig A Parish, Matthew B Francis
Enzymatic Modification of N-Terminal Proline Residues Using Phenol Derivatives. Journal of the American Chemical Society 141 (9) (2019)
Sobhana Babu Boga, Shane W Krska, Songnian Lin, Dmitri Pissarnitski, Lin Yan, Ahmet Kekec, Weijuan Tang, Nicholas A Pierson, Christopher A Strulson, Eric Streckfuss, Xiaohong Zhu, Xiaoping Zhang, Terri Kelly, Craig A Parish
Site-Selective Synthesis of Insulin Azides and Bioconjugates. Bioconjugate chemistry 30 (4) (2019)
Naoko Ichiishi, John P Caldwell, Melissa Lin, Wendy Zhong, Xiaohong Zhu, Eric Streckfuss, Hai-Young Kim, Craig A Parish, Shane W Krska
Protecting group free radical C-H trifluoromethylation of peptides. Chemical science 9 (17) (2018)
Shane W Krska, Daniel A DiRocco, Spencer D Dreher, Michael Shevlin
The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis. Accounts of chemical research 50 (12) (2017)

Shane W Krska.css-eqlu8i{font-size:small;padding-left:4px;} (Shane Krska)

Publication Activity (10 Years)

Top Topics

Top Venues

Shane W Krska (Shane Krska)