David W C MacMillan

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 89

Top Topics

Molecular Docking

Respiratory Syndrome Coronavirus

Gold Nanoparticles

Energy Transfer

Top Venues

Journal of the American Chemical Society

Science (New York, N.Y.)

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature (2024)
Qinyan Cai, Iona M McWhinnie, Nathan W Dow, Amy Y Chan, David W C MacMillan
Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling. Journal of the American Chemical Society (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature 628 (8006) (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature 628 (8007) (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature 631 (8022) (2024)
Edna Mao, Cesar N Prieto Kullmer, Holt A Sakai, David W C MacMillan
Direct Bioisostere Replacement Enabled by Metallaphotoredox Deoxydifluoromethylation. Journal of the American Chemical Society 146 (8) (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature 628 (8006) (2024)
Chenmengxiao Roderick Pan, Steve D Knutson, Sean W Huth, David W C MacMillan
µMap proximity labeling in living cells reveals stress granule disassembly mechanisms. Nature chemical biology (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature 628 (8007) (2024)
Edna Mao, Cesar N Prieto Kullmer, Holt A Sakai, David W C MacMillan
Direct Bioisostere Replacement Enabled by Metallaphotoredox Deoxydifluoromethylation. Journal of the American Chemical Society 146 (8) (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature (2024)
Edna Mao, Cesar N Prieto Kullmer, Holt A Sakai, David W C MacMillan
Direct Bioisostere Replacement Enabled by Metallaphotoredox Deoxydifluoromethylation. Journal of the American Chemical Society 146 (8) (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature 628 (8006) (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature (2024)
Johnny Z Wang, Edna Mao, Jennifer A Nguyen, William L Lyon, David W C MacMillan
Triple Radical Sorting: Aryl-Alkylation of Alkenes. Journal of the American Chemical Society (2024)
Johnny Z Wang, Edna Mao, Jennifer A Nguyen, William L Lyon, David W C MacMillan
Triple Radical Sorting: Aryl-Alkylation of Alkenes. Journal of the American Chemical Society 146 (23) (2024)
Edna Mao, Cesar N Prieto Kullmer, Holt A Sakai, David W C MacMillan
Direct Bioisostere Replacement Enabled by Metallaphotoredox Deoxydifluoromethylation. Journal of the American Chemical Society (2024)
Alice Long, Christian J Oswood, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Couple-close construction of polycyclic rings from diradicals. Nature 628 (8007) (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature 631 (8022) (2024)
Benjamin T Boyle, Nathan W Dow, Christopher B Kelly, Marian C Bryan, David W C MacMillan
Unlocking carbene reactivity by metallaphotoredox α-elimination. Nature 631 (8022) (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature (2024)
Qinyan Cai, Iona M McWhinnie, Nathan W Dow, Amy Y Chan, David W C MacMillan
Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling. Journal of the American Chemical Society 146 (18) (2024)
Ruizhe Chen, Nicholas E Intermaggio, Jiaxin Xie, James A Rossi-Ashton, Colin A Gould, Robert T Martin, Jesus Alcazar, David W C MacMillan
Alcohol-alcohol cross-coupling enabled by S H 2 radical sorting. Science (New York, N.Y.) 383 (6689) (2024)
Johnny Z Wang, William L Lyon, David W C MacMillan
Alkene dialkylation by triple radical sorting. Nature (2024)
Qinyan Cai, Iona M McWhinnie, Nathan W Dow, Amy Y Chan, David W C MacMillan
Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling. Journal of the American Chemical Society 146 (18) (2024)
Edna Mao, Cesar N Prieto Kullmer, Holt A Sakai, David W C MacMillan
Direct Bioisostere Replacement Enabled by Metallaphotoredox Deoxydifluoromethylation. Journal of the American Chemical Society 146 (8) (2024)
Edna Mao, David W C MacMillan
Late-Stage C( sp 3 )-H Methylation of Drug Molecules. Journal of the American Chemical Society 145 (5) (2023)
Olivia L Garry, Michael Heilmann, Jingjia Chen, Yufan Liang, Xiaheng Zhang, Xiaoshen Ma, Charles S Yeung, David Jonathan Bennett, David W C MacMillan
Rapid Access to 2-Substituted Bicyclo[1.1.1]pentanes. Journal of the American Chemical Society (2023)
David F Fernández, María González-Esguevillas, Sebastian Keess, Felix Schäfer, Jens Mohr, Andre Shavnya, Thomas Knauber, David C Blakemore, David W C MacMillan
Redefining the Synthetic Logic of Medicinal Chemistry. Photoredox-Catalyzed Reactions as a General Tool for Aliphatic Core Functionalization. Organic letters (2023)
David F Fernández, María González-Esguevillas, Sebastian Keess, Felix Schäfer, Jens Mohr, Andre Shavnya, Thomas Knauber, David C Blakemore, David W C MacMillan
Redefining the Synthetic Logic of Medicinal Chemistry. Photoredox-Catalyzed Reactions as a General Tool for Aliphatic Core Functionalization. Organic letters (2023)
P Scott Pedersen, David C Blakemore, Gary M Chinigo, Thomas Knauber, David W C MacMillan
One-Pot Synthesis of Sulfonamides from Unactivated Acids and Amines via Aromatic Decarboxylative Halosulfonylation. Journal of the American Chemical Society (2023)
Edna Mao, David W C MacMillan
Late-Stage C( sp 3 )-H Methylation of Drug Molecules. Journal of the American Chemical Society 145 (5) (2023)
Sean W Huth, James V Oakley, Ciaran P Seath, Jacob B Geri, Aaron D Trowbridge, Dann L Parker, Frances P Rodriguez-Rivera, Adam G Schwaid, Carlo P Ramil, Keun Ah Ryu, Cory H White, Olugbeminiyi O Fadeyi, Rob C Oslund, David W C MacMillan
μMap Photoproximity Labeling Enables Small Molecule Binding Site Mapping. Journal of the American Chemical Society (2023)
Olivia L Garry, Michael Heilmann, Jingjia Chen, Yufan Liang, Xiaheng Zhang, Xiaoshen Ma, Charles S Yeung, David Jonathan Bennett, David W C MacMillan
Rapid Access to 2-Substituted Bicyclo[1.1.1]pentanes. Journal of the American Chemical Society 145 (5) (2023)
David F Fernández, María González-Esguevillas, Sebastian Keess, Felix Schäfer, Jens Mohr, Andre Shavnya, Thomas Knauber, David C Blakemore, David W C MacMillan
Redefining the Synthetic Logic of Medicinal Chemistry. Photoredox-Catalyzed Reactions as a General Tool for Aliphatic Core Functionalization. Organic letters (2023)
William P Carson Ii, Patrick J Sarver, Noelle S Goudy, David W C MacMillan
Photoredox Catalysis-Enabled Sulfination of Alcohols and Bromides. Journal of the American Chemical Society (2023)
Edna Mao, David W C MacMillan
Late-Stage C( sp 3 )-H Methylation of Drug Molecules. Journal of the American Chemical Society 145 (5) (2023)
Colin A Gould, Andria L Pace, David W C MacMillan
Rapid and Modular Access to Quaternary Carbons from Tertiary Alcohols via Bimolecular Homolytic Substitution. Journal of the American Chemical Society (2023)
Ciaran P Seath, Antony J Burton, Xuemeng Sun, Gihoon Lee, Ralph E Kleiner, David W C MacMillan, Tom W Muir
Tracking chromatin state changes using nanoscale photo-proximity labelling. Nature (2023)
Edna Mao, David W C MacMillan
Late-Stage C( sp 3 )-H Methylation of Drug Molecules. Journal of the American Chemical Society (2023)
Amy Y Chan, Atanu Ghosh, Jonathan T Yarranton, Jack Twilton, Jian Jin, Daniela M Arias-Rotondo, Holt A Sakai, James K McCusker, David W C MacMillan
Exploiting the Marcus inverted region for first-row transition metal-based photoredox catalysis. Science (New York, N.Y.) 382 (6667) (2023)
Mario P Wiesenfeldt, James A Rossi-Ashton, Ian B Perry, Johannes Diesel, Olivia L Garry, Florian Bartels, Susannah C Coote, Xiaoshen Ma, Charles S Yeung, David Jonathan Bennett, David W C MacMillan
General Access to Cubanes as Benzene Bioisosteres. Nature (2023)
Sebastian B Beil, Tiffany Q Chen, Nicholas E Intermaggio, David W C MacMillan
Carboxylic Acids as Adaptive Functional Groups in Metallaphotoredox Catalysis. Accounts of chemical research 55 (23) (2022)
Tiffany Q Chen, P Scott Pedersen, Nathan W Dow, Remi Fayad, Cory E Hauke, Michael C Rosko, Evgeny O Danilov, David C Blakemore, Anne-Marie Dechert-Schmitt, Thomas Knauber, Felix N Castellano, David W C MacMillan
A Unified Approach to Decarboxylative Halogenation of (Hetero)aryl Carboxylic Acids. Journal of the American Chemical Society 144 (18) (2022)
Cesar N Prieto Kullmer, Jacob A Kautzky, Shane W Krska, Timothy Nowak, Spencer D Dreher, David W C MacMillan
Accelerating reaction generality and mechanistic insight through additive mapping. Science (New York, N.Y.) 376 (6592) (2022)
Claudio F Meyer, Ciaran P Seath, Steve D Knutson, Wenyun Lu, Joshua D Rabinowitz, David W C MacMillan
Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. Journal of the American Chemical Society (2022)
Artem V Tsymbal, Lorenzo Delarue Bizzini, David W C MacMillan
Nickel Catalysis via S H 2 Homolytic Substitution: The Double Decarboxylative Cross-Coupling of Aliphatic Acids. Journal of the American Chemical Society 144 (46) (2022)
Holt A Sakai, David W C MacMillan
Nontraditional Fragment Couplings of Alcohols and Carboxylic Acids: C( sp 3 )-C( sp 3 ) Cross-Coupling via Radical Sorting. Journal of the American Chemical Society 144 (14) (2022)
Johnny Z Wang, Holt A Sakai, David W C MacMillan
Alcohols as Alkylating Agents: Photoredox-Catalyzed Conjugate Alkylation via In Situ Deoxygenation. Angewandte Chemie (International ed. in English) 61 (35) (2022)
Claudio F Meyer, Ciaran P Seath, Steve D Knutson, Wenyun Lu, Joshua D Rabinowitz, David W C MacMillan
Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. Journal of the American Chemical Society 144 (51) (2022)
Nathan W Dow, P Scott Pedersen, Tiffany Q Chen, David C Blakemore, Anne-Marie Dechert-Schmitt, Thomas Knauber, David W C MacMillan
Decarboxylative Borylation and Cross-Coupling of (Hetero)aryl Acids Enabled by Copper Charge Transfer Catalysis. Journal of the American Chemical Society 144 (14) (2022)
Claudio F Meyer, Ciaran P Seath, Steve D Knutson, Wenyun Lu, Joshua D Rabinowitz, David W C MacMillan
Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. Journal of the American Chemical Society 144 (51) (2022)
Claudio F Meyer, Ciaran P Seath, Steve D Knutson, Wenyun Lu, Joshua D Rabinowitz, David W C MacMillan
Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. Journal of the American Chemical Society 144 (51) (2022)
Benito F Buksh, Steve D Knutson, James V Oakley, Noah B Bissonnette, Daniel G Oblinsky, Michael P Schwoerer, Ciaran P Seath, Jacob B Geri, Frances P Rodriguez-Rivera, Dann L Parker, Gregory D Scholes, Alexander Ploss, David W C MacMillan
μMap-Red: Proximity Labeling by Red Light Photocatalysis. Journal of the American Chemical Society 144 (14) (2022)
Saori Suzuki, Jacob B Geri, Steve D Knutson, Harris Bell-Temin, Tomokazu Tamura, David F Fernández, Gabrielle H Lovett, Nicholas A Till, Brigitte L Heller, Jinchao Guo, David W C MacMillan, Alexander Ploss
Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap. Journal of the American Chemical Society 144 (36) (2022)
Agustin Millet, Paul T Cesana, Kassandra Sedillo, Matthew J Bird, Gabriela S Schlau-Cohen, Abigail G Doyle, David W C MacMillan, Gregory D Scholes
Bioinspired Supercharging of Photoredox Catalysis for Applications in Energy and Chemical Manufacturing. Accounts of chemical research 55 (10) (2022)
Yimon Aye, Kevin R Campos, David W C MacMillan
Go to the Board: A Journey through the Life of Professor David A. Evans. ACS chemical biology 17 (8) (2022)
Christian J Oswood, David W C MacMillan
Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols. Journal of the American Chemical Society 144 (1) (2021)
Wei Liu, Marissa N Lavagnino, Colin A Gould, Jesus Alcazar, David W C MacMillan
A biomimetic SH2 cross-coupling mechanism for quaternary sp3-carbon formation. Science (New York, N.Y.) 374 (6572) (2021)
Tomer M Faraggi, Caroline Rouget-Virbel, Juan A Rincón, Mario Barberis, Carlos Mateos, Susana García-Cerrada, Javier Agejas, Oscar de Frutos, David W C MacMillan
Synthesis of Enantiopure Unnatural Amino Acids by Metallaphotoredox Catalysis. Organic process research & development 25 (8) (2021)
Nicholas A Till, Seokjoon Oh, David W C MacMillan, Matthew J Bird
The Application of Pulse Radiolysis to the Study of Ni(I) Intermediates in Ni-Catalyzed Cross-Coupling Reactions. Journal of the American Chemical Society 143 (25) (2021)
María González-Esguevillas, David F Fernández, Juan A Rincón, Mario Barberis, Oscar de Frutos, Carlos Mateos, Susana García-Cerrada, Javier Agejas, David W C MacMillan
Rapid Optimization of Photoredox Reactions for Continuous-Flow Systems Using Microscale Batch Technology. ACS central science 7 (7) (2021)
Patrick J Sarver, Noah B Bissonnette, David W C MacMillan
Decatungstate-Catalyzed C(sp3)-H Sulfinylation: Rapid Access to Diverse Organosulfur Functionality. Journal of the American Chemical Society 143 (26) (2021)
Amy Y Chan, Ian B Perry, Noah B Bissonnette, Benito F Buksh, Grant A Edwards, Lucas I Frye, Olivia L Garry, Marissa N Lavagnino, Beryl X Li, Yufan Liang, Edna Mao, Agustin Millet, James V Oakley, Nicholas L Reed, Holt A Sakai, Ciaran P Seath, David W C MacMillan
Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysis. Chemical reviews (2021)
Xiangbo Zhao, David W C MacMillan
Metallaphotoredox Perfluoroalkylation of Organobromides. Journal of the American Chemical Society 142 (46) (2020)
Jacob S DeHovitz, Yong Yao Loh, Jacob A Kautzky, Kazunori Nagao, Andrew J Meichan, Motoshi Yamauchi, David W C MacMillan, Todd K Hyster
Static to inducibly dynamic stereocontrol: The convergent use of racemic β-substituted ketones. Science (New York, N.Y.) 369 (6507) (2020)
Nicholas A Till, Lei Tian, Zhe Dong, Gregory D Scholes, David W C MacMillan
Mechanistic Analysis of Metallaphotoredox C-N Coupling: Photocatalysis Initiates and Perpetuates Ni(I)/Ni(III) Coupling Activity. Journal of the American Chemical Society 142 (37) (2020)
Junyong Kim, Beryl X Li, Richard Y-C Huang, Jennifer X Qiao, William R Ewing, David W C MacMillan
Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis. Journal of the American Chemical Society 142 (51) (2020)
Holt A Sakai, Wei Liu, Chi Chip Le, David W C MacMillan
Cross-Electrophile Coupling of Unactivated Alkyl Chlorides. Journal of the American Chemical Society 142 (27) (2020)
Lei Tian, Nicholas A Till, Bryan Kudisch, David W C MacMillan, Gregory D Scholes
Transient Absorption Spectroscopy Offers Mechanistic Insights for an Iridium/Nickel-Catalyzed C-O Coupling. Journal of the American Chemical Society 142 (10) (2020)
Jacob B Geri, James V Oakley, Tamara Reyes-Robles, Tao Wang, Stefan J McCarver, Cory H White, Frances P Rodriguez-Rivera, Dann L Parker, Erik C Hett, Olugbeminiyi O Fadeyi, Rob C Oslund, David W C MacMillan
Microenvironment mapping via Dexter energy transfer on immune cells. Science (New York, N.Y.) 367 (6482) (2020)
David J P Kornfilt, David W C MacMillan
Copper-Catalyzed Trifluoromethylation of Alkyl Bromides. Journal of the American Chemical Society 141 (17) (2019)
Gabrielle H Lovett, Shuming Chen, Xiao-Song Xue, Kendall N Houk, David W C MacMillan
Open-Shell Fluorination of Alkyl Bromides: Unexpected Selectivity in a Silyl Radical-Mediated Chain Process. Journal of the American Chemical Society 141 (51) (2019)
Tiffany Q Chen, David W C MacMillan
A Metallaphotoredox Strategy for the Cross-Electrophile Coupling of α-Chloro Carbonyls with Aryl Halides. Angewandte Chemie (International ed. in English) 58 (41) (2019)
Vlad Bacauanu, Sébastien Cardinal, Motoshi Yamauchi, Masaru Kondo, David F Fernández, Richard Remy, David W C MacMillan
Metallaphotoredox Difluoromethylation of Aryl Bromides. Angewandte Chemie (International ed. in English) 57 (38) (2018)
Russell T Smith, Xiaheng Zhang, Juan A Rincón, Javier Agejas, Carlos Mateos, Mario Barberis, Susana García-Cerrada, Oscar de Frutos, David W C MacMillan
Metallaphotoredox-Catalyzed Cross-Electrophile Csp3-Csp3 Coupling of Aliphatic Bromides. Journal of the American Chemical Society 140 (50) (2018)
Jacob A Kautzky, Tao Wang, Ryan W Evans, David W C MacMillan
Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids. Journal of the American Chemical Society 140 (21) (2018)
Taehoon Kim, Stefan J McCarver, Chulbom Lee, David W C MacMillan
Sulfonamidation of Aryl and Heteroaryl Halides through Photosensitized Nickel Catalysis. Angewandte Chemie (International ed. in English) 57 (13) (2018)
Nicholas A Till, Russell T Smith, David W C MacMillan
Decarboxylative Hydroalkylation of Alkynes. Journal of the American Chemical Society 140 (17) (2018)
Jack Twilton, Melodie Christensen, Daniel A DiRocco, Rebecca T Ruck, Ian W Davies, David W C MacMillan
Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α-Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis. Angewandte Chemie (International ed. in English) 57 (19) (2018)
Chip Le, Tiffany Q Chen, Tao Liang, Patricia Z Musacchio, David W C MacMillan
A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes. Science (New York, N.Y.) 360 (6392) (2018)
Eric D Nacsa, David W C MacMillan
Spin-Center Shift-Enabled Direct Enantioselective α-Benzylation of Aldehydes with Alcohols. Journal of the American Chemical Society 140 (9) (2018)
Yong Yao Loh, Kazunori Nagao, Andrew J Hoover, David Hesk, Nelo R Rivera, Steven L Colletti, Ian W Davies, David W C MacMillan
Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds. Science (New York, N.Y.) 358 (6367) (2017)
Xiaheng Zhang, David W C MacMillan
Direct Aldehyde C-H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis. Journal of the American Chemical Society 139 (33) (2017)