Stephen J Tapscott

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Topics

Transcription Factor

Dna Damage Response

Juvenile Idiopathic Arthritis

Muscular Dystrophy

Top Venues

Human molecular genetics

The Journal of cell biology

Skeletal muscle

This page only lists publications with an associated author ORCID identifier.

Publications

Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Chao-Jen Wong, Seth D Friedman, Lauren Snider, Sean R Bennett, Takako I Jones, Peter L Jones, Dennis W W Shaw, Silvia S Blemker, Lara Riem, Olivia DuCharme, Richard J L F Lemmers, Silvère M van der Maarel, Leo H Wang, Rabi Tawil, Jeffrey M Statland, Stephen J Tapscott
Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression. Human molecular genetics (2024)
Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Tessa Arends, Danielle C Hamm, Silvère van der Maarel, Stephen J Tapscott
Facioscapulohumeral Dystrophy: Molecular Basis and Therapeutic Opportunities. Cold Spring Harbor perspectives in biology (2024)
Chao-Jen Wong, Seth D Friedman, Lauren Snider, Sean R Bennett, Takako I Jones, Peter L Jones, Dennis W W Shaw, Silvia S Blemker, Lara Riem, Olivia DuCharme, Richard J L F Lemmers, Silvère M van der Maarel, Leo H Wang, Rabi Tawil, Jeffrey M Statland, Stephen J Tapscott
Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression. Human molecular genetics 33 (8) (2024)
Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Chao-Jen Wong, Seth D Friedman, Lauren Snider, Sean R Bennett, Takako I Jones, Peter L Jones, Dennis W W Shaw, Silvia S Blemker, Lara Riem, Olivia DuCharme, Richard J L F Lemmers, Silvère M van der Maarel, Leo H Wang, Rabi Tawil, Jeffrey M Statland, Stephen J Tapscott
Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression. Human molecular genetics 33 (8) (2024)
Chao-Jen Wong, Seth D Friedman, Lauren Snider, Sean R Bennett, Takako I Jones, Peter L Jones, Dennis W W Shaw, Silvia S Blemker, Lara Riem, Olivia DuCharme, Richard J L F Lemmers, Silvère M van der Maarel, Leo H Wang, Rabi Tawil, Jeffrey M Statland, Stephen J Tapscott
Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression. Human molecular genetics (2024)
Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Tessa Arends, Hiroshi Tsuchida, Richard O Adeyemi, Stephen J Tapscott
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response. The Journal of cell biology 223 (5) (2024)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Danielle C Hamm, Ellen M Paatela, Sean R Bennett, Chao-Jen Wong, Amy E Campbell, Cynthia L Wladyka, Andrew A Smith, Sujatha Jagannathan, Andrew C Hsieh, Stephen J Tapscott
The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. PLoS biology 21 (9) (2023)
Yee Nip, Sean R Bennett, Andrew A Smith, Takako I Jones, Peter L Jones, Stephen J Tapscott
Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD. Human molecular genetics (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Amy E Spens, Nicholas A Sutliff, Sean R Bennett, Amy E Campbell, Stephen J Tapscott
Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction. eLife 12 (2023)
Chao-Jen Wong, Leo Wang, V Michael Holers, Ashley Frazer-Abel, Silvère M van der Maarel, Rabi Tawil, Jeffrey M Statland, Stephen J Tapscott, null null
Elevated plasma complement components in facioscapulohumeral dystrophy. Human molecular genetics 31 (11) (2022)
Chao-Jen Wong, Jennifer L Whiddon, Ashlee T Langford, Andrea E Belleville, Stephen J Tapscott
Canine DUXC: Implications for DUX4 retrotransposition and preclinical models of FSHD. Human molecular genetics (2021)
Sujatha Jagannathan, Yuko Ogata, Philip R Gafken, Stephen J Tapscott, Robert K Bradley
Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy. eLife 8 (2019)
Remko Goossens, Marlinde L van den Boogaard, Richard J L F Lemmers, Judit Balog, Patrick J van der Vliet, Iris M Willemsen, Julie Schouten, Ignazio Maggio, Nienke van der Stoep, Wytske M van Weerden, Stephen J Tapscott, Niels Geijsen, Manuel A F V Gonçalves, Sabrina Sacconi, Rabi Tawil, Silvère M van der Maarel
Intronic SMCHD1 variants in FSHD: testing the potential for CRISPR-Cas9 genome editing. Journal of medical genetics 56 (12) (2019)
Amy E Campbell, Sean C Shadle, Sujatha Jagannathan, Jong-Won Lim, Rebecca Resnick, Rabi Tawil, Silvère M van der Maarel, Stephen J Tapscott
NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins. eLife 7 (2018)
Yosuke Hiramuki, Stephen J Tapscott
Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage. Skeletal muscle 8 (1) (2018)
Sean C Shadle, Jun Wen Zhong, Amy E Campbell, Melissa L Conerly, Sujatha Jagannathan, Chao-Jen Wong, Timothy D Morello, Silvère M van der Maarel, Stephen J Tapscott
DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS genetics 13 (3) (2017)
Amy E Campbell, Jonathan Oliva, Matthew P Yates, Jun Wen Zhong, Sean C Shadle, Lauren Snider, Nikita Singh, Shannon Tai, Yosuke Hiramuki, Rabi Tawil, Silvère M van der Maarel, Stephen J Tapscott, Francis M Sverdrup
BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells. Skeletal muscle 7 (1) (2017)