Stephen J Walsh

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 19

Top Topics

Diffusion Weighted

Top Venues

Chemical communications (Cambridge, England)

Chemical science

Organic & biomolecular chemistry

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Nicola Ashman, Jonathan D Bargh, Stephen J Walsh, Ryan D Greenwood, Arnaud Tiberghien, Jason S Carroll, David R Spring
Peroxide-cleavable linkers for antibody-drug conjugates. Chemical communications (Cambridge, England) 59 (13) (2023)
Teodors Pantelejevs, Pedro Zuazua-Villar, Oliwia Koczy, Andrew J Counsell, Stephen J Walsh, Naomi S Robertson, David R Spring, Jessica A Downs, Marko Hyvönen
A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chemical science 14 (47) (2023)
Nicola Ashman, Jonathan D Bargh, Stephen J Walsh, Ryan D Greenwood, Arnaud Tiberghien, Jason S Carroll, David R Spring
Peroxide-cleavable linkers for antibody-drug conjugates. Chemical communications (Cambridge, England) 59 (13) (2023)
Thomas A King, Stephen J Walsh, Mia Kapun, Thomas Wharton, Sona Krajcovicova, Melanie S Glossop, David R Spring
Disulfide re-bridging reagents for single-payload antibody-drug conjugates. Chemical communications (Cambridge, England) (2023)
Nicola Ashman, Jonathan D Bargh, Stephen J Walsh, Ryan D Greenwood, Arnaud Tiberghien, Jason S Carroll, David R Spring
Peroxide-cleavable linkers for antibody-drug conjugates. Chemical communications (Cambridge, England) (2023)
Nicola Ashman, Jonathan D Bargh, Stephen J Walsh, Ryan D Greenwood, Arnaud Tiberghien, Jason S Carroll, David R Spring
Peroxide-cleavable linkers for antibody-drug conjugates. Chemical communications (Cambridge, England) 59 (13) (2023)
Abigail R Hanby, Stephen J Walsh, Andrew J Counsell, Nicola Ashman, Kim T Mortensen, Jason S Carroll, David R Spring
Antibody dual-functionalisation enabled through a modular divinylpyrimidine disulfide rebridging strategy. Chemical communications (Cambridge, England) 58 (67) (2022)
Friederike M Dannheim, Stephen J Walsh, Carolina T Orozco, Anders Højgaard Hansen, Jonathan D Bargh, Sophie E Jackson, Nicholas J Bond, Jeremy S Parker, Jason S Carroll, David R Spring
All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading. Chemical science 13 (30) (2022)
Stephen J Walsh, Soleilmane Omarjee, Friederike M Dannheim, Dominique-Laurent Couturier, Dorentina Bexheti, Lee Mendil, Gemma Cronshaw, Toby Fewster, Charlotte Gregg, Cara Brodie, Jodi L Miller, Richard Houghton, Jason S Carroll, David R Spring
Divinylpyrimidine reagents generate antibody-drug conjugates with excellent in vivo efficacy and tolerability. Chemical communications (Cambridge, England) 58 (12) (2022)
Andrew J Counsell, Stephen J Walsh, Naomi S Robertson, Hannah F Sore, David R Spring
Efficient and selective antibody modification with functionalised divinyltriazines. Organic & biomolecular chemistry 18 (25) (2021)
Stephen J Walsh, Jessica Iegre, Hikaru Seki, Jonathan D Bargh, Hannah F Sore, Jeremy S Parker, Jason S Carroll, David R Spring
General dual functionalisation of biomacromolecules via a cysteine bridging strategy. Organic & biomolecular chemistry 18 (22) (2021)
Hikaru Seki, Stephen J Walsh, Jonathan D Bargh, Jeremy S Parker, Jason S Carroll, David R Spring
Rapid and robust cysteine bioconjugation with vinylheteroarenes. Chemical science 12 (26) (2021)
Talia R Pettigrew, Rachel J Porter, Stephen J Walsh, Michael P Housden, Nelson Y S Lam, Jason S Carroll, Jeremy S Parker, David R Spring, Ian Paterson
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents. Chemical communications (Cambridge, England) 56 (10) (2020)
Jiraborrirak Charoenpattarapreeda, Stephen J Walsh, Jason S Carroll, David R Spring
Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics. Angewandte Chemie (International ed. in English) 59 (51) (2020)
Jonathan D Bargh, Stephen J Walsh, Albert Isidro-Llobet, Soleilmane Omarjee, Jason S Carroll, David R Spring
Sulfatase-cleavable linkers for antibody-drug conjugates. Chemical science 11 (9) (2020)
Jiraborrirak Charoenpattarapreeda, Yaw Sing Tan, Jessica Iegre, Stephen J Walsh, Elaine Fowler, Rohan S Eapen, Yuteng Wu, Hannah F Sore, Chandra Shekhar Verma, Laura S Itzhaki, David R Spring
Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides. Chemical communications (Cambridge, England) 55 (55) (2019)
Yuteng Wu, Amandeep Kaur, Elaine Fowler, Mareike M Wiedmann, Reginald Young, Warren R J D Galloway, Lasse Olsen, Hannah F Sore, Anasuya Chattopadhyay, Terence T-L Kwan, Wenshu Xu, Stephen J Walsh, Peterson de Andrade, Matej Janecek, Senthil Arumugam, Laura S Itzhaki, Yu Heng Lau, David R Spring
Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides. ACS chemical biology 14 (3) (2019)
Stephen J Walsh, Soleilmane Omarjee, Warren R J D Galloway, Terence T-L Kwan, Hannah F Sore, Jeremy S Parker, Marko Hyvönen, Jason S Carroll, David R Spring
A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates. Chemical science 10 (3) (2018)
Stephen J Walsh, Soleilmane Omarjee, Warren R J D Galloway, Terence T-L Kwan, Hannah F Sore, Jeremy S Parker, Marko Hyvönen, Jason S Carroll, David R Spring
Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates. Chemical science 10 (2) (2018)