Marko Hyvönen

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 45

Top Topics

Cardiopulmonary Resuscitation

Embryonic Stem Cells

Top Venues

Nature communications

Chemical science

Communications biology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Simon R Stockwell, Duncan E Scott, Gerhard Fischer, Estrella Guarino, Timothy P C Rooney, Tzu-Shean Feng, Tommaso Moschetti, Rajavel Srinivasan, Esther Alza, Alice Asteian, Claudio Dagostin, Anna Alcaide, Mathieu Rocaboy, Beata Blaszczyk, Alicia Higueruelo, Xuelu Wang, Maxim Rossmann, Trevor R Perrior, Tom L Blundell, David R Spring, Grahame McKenzie, Chris Abell, John Skidmore, Ashok R Venkitaraman, Marko Hyvönen
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents. Journal of medicinal chemistry (2024)
Katrin Fischer, Aleksei Lulla, Tsz Y So, Pehuén Pereyra-Gerber, Matthew I J Raybould, Timo N Kohler, Juan Carlos Yam-Puc, Tomasz S Kaminski, Robert Hughes, Gwendolyn L Pyeatt, Florian Leiss-Maier, Paul D Brear, Nicholas J Matheson, Charlotte M Deane, Marko Hyvönen, James E D Thaventhiran, Florian Hollfelder
Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells. Nature biotechnology (2024)
Juan Carlos Yam-Puc, Zhaleh Hosseini, Emily C Horner, Pehuén Pereyra Gerber, Nonantzin Beristain-Covarrubias, Robert Hughes, Aleksei Lulla, Maria Rust, Rebecca Boston, Magda Ali, Katrin Fischer, Edward Simmons-Rosello, Martin J O'Reilly, Harry Robson, Lucy H Booth, Lakmini Kahanawita, Andrea Correa-Noguera, David Favara, Lourdes Ceron-Gutierrez, Baerbel Keller, Andrew Craxton, Georgina S F Anderson, Xiao-Ming Sun, Anne Elmer, Caroline Saunders, Areti Bermperi, Sherly Jose, Nathalie Kingston, Thomas E Mulroney, Lucia P G Piñon, null null, Michael A Chapman, Sofia Grigoriadou, Marion MacFarlane, Anne E Willis, Kiran R Patil, Sarah Spencer, Emily Staples, Klaus Warnatz, Matthew S Buckland, Florian Hollfelder, Marko Hyvönen, Rainer Doffinger, Christine Parkinson, Sara Lear, Nicholas J Matheson, James E D Thaventhiran
Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade. Nature communications 14 (1) (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Jerome Jatzlau, Wiktor Burdzinski, Michael Trumpp, Leon Obendorf, Kilian Roßmann, Katharina Ravn, Marko Hyvönen, Francesca Bottanelli, Johannes Broichhagen, Petra Knaus
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications biology 6 (1) (2023)
Juan Carlos Yam-Puc, Zhaleh Hosseini, Emily C Horner, Pehuén Pereyra Gerber, Nonantzin Beristain-Covarrubias, Robert Hughes, Aleksei Lulla, Maria Rust, Rebecca Boston, Magda Ali, Katrin Fischer, Edward Simmons-Rosello, Martin J O'Reilly, Harry Robson, Lucy H Booth, Lakmini Kahanawita, Andrea Correa-Noguera, David Favara, Lourdes Ceron-Gutierrez, Baerbel Keller, Andrew Craxton, Georgina S F Anderson, Xiao-Ming Sun, Anne Elmer, Caroline Saunders, Areti Bermperi, Sherly Jose, Nathalie Kingston, Thomas E Mulroney, Lucia P G Piñon, null null, Michael A Chapman, Sofia Grigoriadou, Marion MacFarlane, Anne E Willis, Kiran R Patil, Sarah Spencer, Emily Staples, Klaus Warnatz, Matthew S Buckland, Florian Hollfelder, Marko Hyvönen, Rainer Doffinger, Christine Parkinson, Sara Lear, Nicholas J Matheson, James E D Thaventhiran
Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade. Nature communications 14 (1) (2023)
Maximilian A J Harman, Steven J Stanway, Heather S Scott, Yuliya Demydchuk, Gustavo Arruda Bezerra, Simone Pellegrino, Liuhong Chen, Paul D Brear, Aleksei Lulla, Marko Hyvönen, Paul J Beswick, Michael J Skynner
Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2. Journal of medicinal chemistry (2023)
Jerome Jatzlau, Wiktor Burdzinski, Michael Trumpp, Leon Obendorf, Kilian Roßmann, Katharina Ravn, Marko Hyvönen, Francesca Bottanelli, Johannes Broichhagen, Petra Knaus
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications biology 6 (1) (2023)
Juan Carlos Yam-Puc, Zhaleh Hosseini, Emily C Horner, Pehuén Pereyra Gerber, Nonantzin Beristain-Covarrubias, Robert Hughes, Aleksei Lulla, Maria Rust, Rebecca Boston, Magda Ali, Katrin Fischer, Edward Simmons-Rosello, Martin J O'Reilly, Harry Robson, Lucy H Booth, Lakmini Kahanawita, Andrea Correa-Noguera, David Favara, Lourdes Ceron-Gutierrez, Baerbel Keller, Andrew Craxton, Georgina S F Anderson, Xiao-Ming Sun, Anne Elmer, Caroline Saunders, Areti Bermperi, Sherly Jose, Nathalie Kingston, Thomas E Mulroney, Lucia P G Piñon, null null, Michael A Chapman, Sofia Grigoriadou, Marion MacFarlane, Anne E Willis, Kiran R Patil, Sarah Spencer, Emily Staples, Klaus Warnatz, Matthew S Buckland, Florian Hollfelder, Marko Hyvönen, Rainer Doffinger, Christine Parkinson, Sara Lear, Nicholas J Matheson, James E D Thaventhiran
Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade. Nature communications 14 (1) (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Teodors Pantelejevs, Pedro Zuazua-Villar, Oliwia Koczy, Andrew J Counsell, Stephen J Walsh, Naomi S Robertson, David R Spring, Jessica A Downs, Marko Hyvönen
A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase. Chemical science 14 (47) (2023)
Juan Carlos Yam-Puc, Zhaleh Hosseini, Emily C Horner, Pehuén Pereyra Gerber, Nonantzin Beristain-Covarrubias, Robert Hughes, Aleksei Lulla, Maria Rust, Rebecca Boston, Magda Ali, Katrin Fischer, Edward Simmons-Rosello, Martin J O'Reilly, Harry Robson, Lucy H Booth, Lakmini Kahanawita, Andrea Correa-Noguera, David Favara, Lourdes Ceron-Gutierrez, Baerbel Keller, Andrew Craxton, Georgina S F Anderson, Xiao-Ming Sun, Anne Elmer, Caroline Saunders, Areti Bermperi, Sherly Jose, Nathalie Kingston, Thomas E Mulroney, Lucia P G Piñon, null null, Michael A Chapman, Sofia Grigoriadou, Marion MacFarlane, Anne E Willis, Kiran R Patil, Sarah Spencer, Emily Staples, Klaus Warnatz, Matthew S Buckland, Florian Hollfelder, Marko Hyvönen, Rainer Doffinger, Christine Parkinson, Sara Lear, Nicholas J Matheson, James E D Thaventhiran
Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade. Nature communications 14 (1) (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Jerome Jatzlau, Wiktor Burdzinski, Michael Trumpp, Leon Obendorf, Kilian Roßmann, Katharina Ravn, Marko Hyvönen, Francesca Bottanelli, Johannes Broichhagen, Petra Knaus
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications biology 6 (1) (2023)
Jerome Jatzlau, Wiktor Burdzinski, Michael Trumpp, Leon Obendorf, Kilian Roßmann, Katharina Ravn, Marko Hyvönen, Francesca Bottanelli, Johannes Broichhagen, Petra Knaus
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications biology 6 (1) (2023)
Katherine U Gaynor, Marina Vaysburd, Maximilian A J Harman, Anna Albecka, Phillip Jeffrey, Paul Beswick, Guido Papa, Liuhong Chen, Donna L Mallery, Brian McGuinness, Katerine Van Rietschoten, Steven Stanway, Paul D Brear, Aleksei Lulla, Katarzyna A Ciazynska, Veronica T Chang, Joanne Sharp, Megan Neary, Helen Box, Jo Herriott, Edyta Kijak, Lee Tatham, Eleanor G Bentley, Parul Sharma, Adam Kirby, Ximeng Han, James P Stewart, Andrew Owen, John A G Briggs, Marko Hyvönen, Michael J Skynner, Leo C James
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nature communications 14 (1) (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Jerome Jatzlau, Wiktor Burdzinski, Michael Trumpp, Leon Obendorf, Kilian Roßmann, Katharina Ravn, Marko Hyvönen, Francesca Bottanelli, Johannes Broichhagen, Petra Knaus
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Communications biology 6 (1) (2023)
Maria Reinecke, Paul D Brear, Larsen Vornholz, Benedict-Tilmann Berger, Florian Seefried, Stephanie Wilhelm, Patroklos Samaras, Laszlo Gyenis, David William Litchfield, Guillaume Médard, Susanne Müller, Jürgen Ruland, Marko Hyvönen, Mathias Wilhelm, Bernhard Kuster
Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors. Nature chemical biology (2023)
Philipp Knyphausen, Mariana Rangel Pereira, Paul D Brear, Marko Hyvönen, Lutz Jermutus, Florian Hollfelder
Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature communications 14 (1) (2023)
Victor Bolsanelli Cioffi, Maria Fernanda de Castro-Amarante, Aleksei Lulla, Robert Andreata-Santos, Mario Costa Cruz, Ana Carolina Ramos Moreno, Mariângela de Oliveira Silva, Bianca M Peres, Lúcio Holanda Gondim de Freitas-Júnior, Carolina Borsoi Moraes, Edison Luiz Durigon, Nicola Coker Gordon, Marko Hyvönen, Luis Carlos de Souza Ferreira, Andrea Balan
SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies. Scientific reports 13 (1) (2023)
Stefanie Neun, Paul D Brear, Eleanor Campbell, Theodora Tryfona, Kamel El Omari, Armin Wagner, Paul Dupree, Marko Hyvönen, Florian Hollfelder
Functional metagenomic screening identifies an unexpected β-glucuronidase. Nature chemical biology 18 (10) (2022)
Umberto Maria Battisti, Chunxia Gao, Oscar J Nilsson, Fady Akladios, Aleksei Lulla, Agnieszka Bogucka, Amalyn Nain-Perez, Liliana Håversen, Woonghee Kim, Jan Borén, Marko Hyvönen, Mathias Uhlen, Adil Mardinglu, Morten Grøtli
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase. Chembiochem : a European journal of chemical biology (2022)
Eleanor L Atkinson, Jessica Iegre, Claudio D'Amore, Paul D Brear, Mauro Salvi, Marko Hyvönen, David R Spring
Development of small cyclic peptides targeting the CK2α/β interface. Chemical communications (Cambridge, England) 58 (30) (2022)
Marie Synakewicz, Rohan S Eapen, Albert Perez-Riba, Pamela J E Rowling, Daniela Bauer, Andreas Weißl, Gerhard Fischer, Marko Hyvönen, Matthias Rief, Laura S Itzhaki, Johannes Stigler
Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix. ACS nano 16 (3) (2022)
Matthew Ratcliff, Richard Xu Zhou, Lutz Jermutus, Marko Hyvönen
The role of pro-domains in human growth factors and cytokines. Biochemical Society transactions 49 (5) (2022)
Paul Brear, Claudia De Fusco, Eleanor L Atkinson, Jessica Iegre, Nicola J Francis-Newton, Ashok R Venkitaraman, Marko Hyvönen, David R Spring
A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action. RSC medicinal chemistry 13 (11) (2022)
Alexander V Strizhak, Oleg Babii, Sergii Afonin, Iuliia Bakanovich, Teodors Pantelejevs, Wenshu Xu, Elaine Fowler, Rohan S Eapen, Krishna Sharma, Maxim O Platonov, Vasyl V Hurmach, Laura Itzhaki, Marko Hyvönen, Anne S Ulrich, David R Spring, Igor V Komarov
Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction. Organic & biomolecular chemistry 18 (28) (2021)
Anassuya Ramachandran, Merima Mehić, Laabiah Wasim, Dessislava Malinova, Ilaria Gori, Beata K Blaszczyk, Diana M Carvalho, Eileen M Shore, Chris Jones, Marko Hyvönen, Pavel Tolar, Caroline S Hill
Pathogenic ACVR1R206H activation by Activin A-induced receptor clustering and autophosphorylation. The EMBO journal 40 (14) (2021)
Jessica Iegre, Eleanor L Atkinson, Paul D Brear, Bethany M Cooper, Marko Hyvönen, David R Spring
Chemical probes targeting the kinase CK2: a journey outside the catalytic box. Organic & biomolecular chemistry 19 (20) (2021)
Laurens H Lindenburg, Teodors Pantelejevs, Fabrice Gielen, Pedro Zuazua-Villar, Maren Butz, Eric Rees, Clemens F Kaminski, Jessica A Downs, Marko Hyvönen, Florian Hollfelder
Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats. Proceedings of the National Academy of Sciences of the United States of America 118 (46) (2021)
Eleanor L Atkinson, Jessica Iegre, Paul D Brear, Elizabeth A Zhabina, Marko Hyvönen, David R Spring
Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study. Molecules (Basel, Switzerland) 26 (7) (2021)
Nikoleta Kostopoulou, Sofia Bellou, Eleni Bagli, Maria Markou, Eleftherios Kostaras, Marko Hyvönen, Yannis L Kalaidzidis, Angelos Papadopoulos, Varvara Chalmantzi, Athena Kyrkou, Ekaterini Panopoulou, Theodore Fotsis, Carol Murphy
Embryonic stem cells are devoid of macropinocytosis, a trafficking pathway for activin A in differentiated cells. Journal of cell science 134 (13) (2021)
Sarah L Kidd, Elaine Fowler, Till Reinhardt, Thomas Compton, Natalia Mateu, Hector Newman, Dom Bellini, Romain Talon, Joseph McLoughlin, Tobias Krojer, Anthony Aimon, Anthony Bradley, Michael Fairhead, Paul D Brear, Laura Díaz-Sáez, Katherine McAuley, Hannah F Sore, Andrew Madin, Daniel H O' Donovan, Kilian V M Huber, Marko Hyvönen, Frank von Delft, Christopher G Dowson, David R Spring
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion. Chemical science 11 (39) (2020)
Emma-Ruoqi Xu, Aleix Lafita, Alex Bateman, Marko Hyvönen
The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers. Acta crystallographica. Section D, Structural biology 76 (Pt 2) (2020)
Paul Brear, Darby Ball, Katherine Stott, Sheena D'Arcy, Marko Hyvönen
Proposed Allosteric Inhibitors Bind to the ATP Site of CK2α. Journal of medicinal chemistry 63 (21) (2020)
Jessica Iegre, Paul D Brear, David J Baker, Yaw Sing Tan, Eleanor L Atkinson, Hannah F Sore, Daniel H O' Donovan, Chandra Shekhar Verma, Marko Hyvönen, David R Spring
Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction. Chemical science 10 (19) (2019)
Ryan G Walker, Jason C McCoy, Magdalena Czepnik, Melanie J Mills, Adam Hagg, Kelly L Walton, Thomas R Cotton, Marko Hyvönen, Richard T Lee, Paul Gregorevic, Craig A Harrison, Thomas B Thompson
Molecular characterization of latent GDF8 reveals mechanisms of activation. Proceedings of the National Academy of Sciences of the United States of America 115 (5) (2018)
Charlotte M Miton, Stefanie Jonas, Gerhard Fischer, Fernanda Duarte, Mark F Mohamed, Bert van Loo, Bálint Kintses, Shina Caroline Lynn Kamerlin, Nobuhiko Tokuriki, Marko Hyvönen, Florian Hollfelder
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset. Proceedings of the National Academy of Sciences of the United States of America 115 (31) (2018)
Stephen J Walsh, Soleilmane Omarjee, Warren R J D Galloway, Terence T-L Kwan, Hannah F Sore, Jeremy S Parker, Marko Hyvönen, Jason S Carroll, David R Spring
A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates. Chemical science 10 (3) (2018)
Jessica Iegre, Paul D Brear, Claudia De Fusco, Masao Yoshida, Sophie L Mitchell, Maxim Rossmann, Laura Carro, Hannah F Sore, Marko Hyvönen, David R Spring
Second-generation CK2α inhibitors targeting the αD pocket. Chemical science 9 (11) (2018)
Stephen J Walsh, Soleilmane Omarjee, Warren R J D Galloway, Terence T-L Kwan, Hannah F Sore, Jeremy S Parker, Marko Hyvönen, Jason S Carroll, David R Spring
Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates. Chemical science 10 (2) (2018)
Thomas R Cotton, Gerhard Fischer, Xuelu Wang, Jason C McCoy, Magdalena Czepnik, Thomas B Thompson, Marko Hyvönen
Structure of the human myostatin precursor and determinants of growth factor latency. The EMBO journal 37 (3) (2018)
Daniel J Cole, Matej Janecek, Jamie E Stokes, Maxim Rossmann, John C Faver, Grahame J McKenzie, Ashok R Venkitaraman, Marko Hyvönen, David R Spring, David J Huggins, William L Jorgensen
Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction. Chemical communications (Cambridge, England) 53 (67) (2018)