Stephen H Safe (Stephen Safe)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 43

Top Topics

Transforming Growth Factor

Transcription Factor

Cancer Stem Cells

Top Venues

International journal of molecular sciences

Molecular cancer research : MCR

Molecular carcinogenesis

This page only lists publications with an associated author ORCID identifier.

Publications

Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen H Safe
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands. Biomolecules 14 (3) (2024)
Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen H Safe
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands. Biomolecules 14 (3) (2024)
Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen H Safe
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands. Biomolecules 14 (3) (2024)
Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen H Safe
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands. Biomolecules 14 (3) (2024)
Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen H Safe
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands. Biomolecules 14 (3) (2024)
Stephen H Safe, Jainish Kothari, Amanuel Hailemariam, Srijana Upadhyay, Laurie A Davidson, Robert S Chapkin
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action. International journal of molecular sciences 24 (3) (2023)
Miok Lee, Srijana Upadhyay, Fuada Mariyam, Greg Martin, Amanuel Hailemariam, Kyongbum Lee, Arul Jayaraman, Robert S Chapkin, Syng-Ook Lee, Stephen H Safe
Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1). International journal of molecular sciences 24 (9) (2023)
Miok Lee, Srijana Upadhyay, Fuada Mariyam, Greg Martin, Amanuel Hailemariam, Kyongbum Lee, Arul Jayaraman, Robert S Chapkin, Syng-Ook Lee, Stephen H Safe
Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1). International journal of molecular sciences 24 (9) (2023)
Stephen H Safe, Jainish Kothari, Amanuel Hailemariam, Srijana Upadhyay, Laurie A Davidson, Robert S Chapkin
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action. International journal of molecular sciences 24 (3) (2023)
Stephen H Safe
Specificity Proteins (Sp) and Cancer. International journal of molecular sciences 24 (6) (2023)
Stephen H Safe, Jainish Kothari, Amanuel Hailemariam, Srijana Upadhyay, Laurie A Davidson, Robert S Chapkin
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action. International journal of molecular sciences 24 (3) (2023)
Lei Zhang, Kumaravel Mohankumar, Gregory Martin, Fuada Mariyam, Yuri Park, Sang Jun Han, Stephen H Safe
Flavonoids Quercetin and Kaempferol Are NR4A1 Antagonists and Suppress Endometriosis in Female Mice. Endocrinology (2023)
Stephen H Safe
Specificity Proteins (Sp) and Cancer. International journal of molecular sciences 24 (6) (2023)
Stephen H Safe
Specificity Proteins (Sp) and Cancer. International journal of molecular sciences 24 (6) (2023)
Stephen H Safe, Jainish Kothari, Amanuel Hailemariam, Srijana Upadhyay, Laurie A Davidson, Robert S Chapkin
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action. International journal of molecular sciences 24 (3) (2023)
John A Baron, Hazel B Nichols, Stephen H Safe
Cigarette Smoking and Estrogen-Related Cancer-Reply. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (10) (2022)
Hyo-Seon Lee, Dae Hwan Kim, In-Seon Lee, Ji-Hyun Park, Gregory Martin, Stephen H Safe, Keuk-Jun Kim, Joung-Hee Kim, Byeong Ik Jang, Syng-Ook Lee
Plant Alkaloid Tetrandrine Is a Nuclear Receptor 4A1 Antagonist and Inhibits Panc-1 Cell Growth In Vitro and In Vivo. International journal of molecular sciences 23 (9) (2022)
Stephen H Safe, Rupesh Shrestha, Kumaravel Mohankumar
Orphan nuclear receptor 4A1 (NR4A1) and novel ligands. Essays in biochemistry 65 (6) (2022)
Stephen H Safe, Lei Zhang
The Role of the Aryl Hydrocarbon Receptor (AhR) and Its Ligands in Breast Cancer. Cancers 14 (22) (2022)
Huajun Han, Laurie A Davidson, Martha Hensel, Grace Yoon, Kerstin Landrock, Clinton D Allred, Arul Jayaraman, Ivan V Ivanov, Stephen H Safe, Robert S Chapkin
Loss of Aryl Hydrocarbon Receptor Promotes Colon Tumorigenesis in ApcS580/+; KrasG12D/+ Mice. Molecular cancer research : MCR 19 (5) (2021)
Stephen H Safe, Arul Jayaraman, Robert S Chapkin, Marcell Howard, Kumaravel Mohankumar, Rupesh Shrestha
Flavonoids: structure-function and mechanisms of action and opportunities for drug development. Toxicological research 37 (2) (2021)
Robert S Chapkin, Laurie A Davidson, Hyejin Park, Un-Ho Jin, Yang-Yi Fan, Yating Cheng, Martha E Hensel, Kerstin K Landrock, Clinton Allred, Rani Menon, Cory Klemashevich, Arul Jayaraman, Stephen H Safe
Role of the Aryl Hydrocarbon Receptor (AhR) in Mediating the Effects of Coffee in the Colon. Molecular nutrition & food research 65 (20) (2021)
Keshav Karki, Kumaravel Mohankumar, Abigail Schoeller, Gregory Martin, Rupesh Shrestha, Stephen H Safe
NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth. Cancers 13 (11) (2021)
Kumaravel Mohankumar, Rupesh Shrestha, Stephen H Safe
Nuclear receptor 4A1 (NR4A1) antagonists target paraspeckle component 1 (PSPC1) in cancer cells. Molecular carcinogenesis 61 (1) (2021)
John A Baron, Hazel B Nichols, Chelsea Anderson, Stephen H Safe
Cigarette Smoking and Estrogen-Related Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (8) (2021)
Yongjian Yang, Daniel Osorio, Laurie A Davidson, Huajun Han, Destiny A Mullens, Arul Jayaraman, Stephen H Safe, Ivan V Ivanov, James J Cai, Robert S Chapkin
Single-cell RNA Sequencing Reveals How the Aryl Hydrocarbon Receptor Shapes Cellular Differentiation Potency in the Mouse Colon. Cancer prevention research (Philadelphia, Pa.) (2021)
Keshav Karki, Gus A Wright, Kumaravel Mohankumar, Un-Ho Jin, Xing-Han Zhang, Stephen H Safe
A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity. Cancer research 80 (5) (2020)
Rupesh Shrestha, Kumaravel Mohankumar, Un-Ho Jin, Gregory G Martin, Stephen H Safe
The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells. Molecular cancer therapeutics 20 (3) (2020)
Stephen H Safe, Keshav Karki
The Paradoxical Roles of Orphan Nuclear Receptor 4A (NR4A) in Cancer. Molecular cancer research : MCR 19 (2) (2020)
Erik Hedrick, Kumaravel Mohankumar, Alexandra Lacey, Stephen H Safe
Inhibition of NR4A1 Promotes ROS Accumulation and IL24-Dependent Growth Arrest in Rhabdomyosarcoma. Molecular cancer research : MCR 17 (11) (2019)
Hyejin Park, Un-Ho Jin, Asuka A Orr, Stephanie P Echegaray, Laurie A Davidson, Clinton D Allred, Robert S Chapkin, Arul Jayaraman, Kyongbum Lee, Phanourios Tamamis, Stephen H Safe
Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships. Chemical research in toxicology 32 (11) (2019)
Ravi Kasiappan, Indira Jutooru, Kumaravel Mohankumar, Keshav Karki, Alexandra Lacey, Stephen H Safe
Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth through Targeting Sp Transcription Factors. Molecular cancer research : MCR 17 (3) (2019)
Un-Ho Jin, Keshav Karki, Yating Cheng, Sharon K Michelhaugh, Sandeep Mittal, Stephen H Safe
The aryl hydrocarbon receptor is a tumor suppressor-like gene in glioblastoma. The Journal of biological chemistry 294 (29) (2019)
Xi Li, Ronald B Tjalkens, Rupesh Shrestha, Stephen H Safe
Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of nuclear receptor 4A2. Chemical biology & drug design 94 (4) (2019)
Keshav Karki, Xi Li, Un-Ho Jin, Kumaravel Mohankumar, Mahsa Zarei, Sharon K Michelhaugh, Sandeep Mittal, Ronald Tjalkens, Stephen H Safe
Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas. Journal of neuro-oncology 146 (1) (2019)
Erik Hedrick, Kumaravel Mohankumar, Stephen H Safe
TGFβ-Induced Lung Cancer Cell Migration Is NR4A1-Dependent. Molecular cancer research : MCR 16 (12) (2018)
Yeon-Seop Jung, Hyo-Seon Lee, Hye-Rin Cho, Keuk-Jun Kim, Joung-Hee Kim, Stephen H Safe, Syng-Ook Lee
Dual targeting of Nur77 and AMPKα by isoalantolactone inhibits adipogenesis in vitro and decreases body fat mass in vivo. International journal of obesity (2005) 43 (5) (2018)
Yating Cheng, Parisa Imanirad, Indira Jutooru, Erik Hedrick, Un-Ho Jin, Aline Rodrigues Hoffman, Jeann Leal de Araujo, Benjamin Morpurgo, Andrei Golovko, Stephen H Safe
Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer. PloS one 13 (2) (2018)
Alexandra Lacey, Erik Hedrick, Yating Cheng, Kumaravel Mohankumar, Melanie Warren, Stephen H Safe
Interleukin-24 (IL24) Is Suppressed by PAX3-FOXO1 and Is a Novel Therapy for Rhabdomyosarcoma. Molecular cancer therapeutics 17 (12) (2018)
Siva Kumar Kolluri, Un-Ho Jin, Stephen H Safe
Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target. Archives of toxicology 91 (7) (2017)
Un-Ho Jin, Yating Cheng, Hyejin Park, Laurie A Davidson, Evelyn S Callaway, Robert S Chapkin, Arul Jayaraman, Andrew Asante, Clinton Allred, Evelyn A Weaver, Stephen H Safe
Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells. Scientific reports 7 (1) (2017)
Erik Hedrick, Syng-Ook Lee, Stephen H Safe
The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists. Molecular carcinogenesis 56 (9) (2017)
Erik Hedrick, Stephen H Safe
Transforming Growth Factor β/NR4A1-Inducible Breast Cancer Cell Migration and Epithelial-to-Mesenchymal Transition Is p38α (Mitogen-Activated Protein Kinase 14) Dependent. Molecular and cellular biology 37 (18) (2017)