Tao Liu

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 14

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Induced Apoptosis

Dna Damage Response

Top Venues

Journal of medicinal chemistry

RSC medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Minjie Deng, Yue Gao, Peipei Wang, Wenjing Du, Gaoya Xu, Jia Li, Yubo Zhou, Tao Liu
Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1. RSC medicinal chemistry 15 (2) (2023)
Minjie Deng, Peipei Wang, Xiubing Long, Gaoya Xu, Chang Wang, Jia Li, Yubo Zhou, Tao Liu
Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors. ChemMedChem (2023)
Xuemei Li, Peipei Wang, Chang Wang, Tingting Jin, Ran Xu, Lexian Tong, Xiaobei Hu, Liteng Shen, Jia Li, Yubo Zhou, Tao Liu
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities. Journal of medicinal chemistry (2023)
Minjie Deng, Yue Gao, Peipei Wang, Wenjing Du, Gaoya Xu, Jia Li, Yubo Zhou, Tao Liu
Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1. RSC medicinal chemistry 15 (2) (2023)
Kailong Jiang, Xuemei Li, Chang Wang, Xiaobei Hu, Peipei Wang, Lexian Tong, Yutong Tu, Beijing Chen, Tingting Jin, Tao Wang, Hanlin Wang, Yubing Han, Renzhao Gui, Jianmin Yang, Tao Liu, Jia Li, Yubo Zhou
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia. Leukemia (2022)
Kailong Jiang, Xuemei Li, Chang Wang, Xiaobei Hu, Peipei Wang, Lexian Tong, Yutong Tu, Beijing Chen, Tingting Jin, Tao Wang, Hanlin Wang, Yubing Han, Renzhao Gui, Jianmin Yang, Tao Liu, Jia Li, Yubo Zhou
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia. Leukemia 37 (3) (2022)
Kailong Jiang, Xuemei Li, Chang Wang, Xiaobei Hu, Peipei Wang, Lexian Tong, Yutong Tu, Beijing Chen, Tingting Jin, Tao Wang, Hanlin Wang, Yubing Han, Renzhao Gui, Jianmin Yang, Tao Liu, Jia Li, Yubo Zhou
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia. Leukemia 37 (3) (2022)
Kailong Jiang, Xuemei Li, Chang Wang, Xiaobei Hu, Peipei Wang, Lexian Tong, Yutong Tu, Beijing Chen, Tingting Jin, Tao Wang, Hanlin Wang, Yubing Han, Renzhao Gui, Jianmin Yang, Tao Liu, Jia Li, Yubo Zhou
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia. Leukemia 37 (3) (2022)
Kailong Jiang, Xuemei Li, Chang Wang, Xiaobei Hu, Peipei Wang, Lexian Tong, Yutong Tu, Beijing Chen, Tingting Jin, Tao Wang, Hanlin Wang, Yubing Han, Renzhao Gui, Jianmin Yang, Tao Liu, Jia Li, Yubo Zhou
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia. Leukemia 37 (3) (2022)
Lexian Tong, Peipei Wang, Xuemei Li, Xiao-Wu Dong, Xiaobei Hu, Chang Wang, Tao Liu, Jia Li, Yubo Zhou
Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT. Journal of medicinal chemistry 65 (4) (2022)
Tingting Jin, Lei Xu, Peipei Wang, Xiaobei Hu, Runyuan Zhang, Zhiqi Wu, Wenxin Du, Weijuan Kan, Kun Li, Chang Wang, Yubo Zhou, Jia Li, Tao Liu
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile. Journal of medicinal chemistry 64 (20) (2021)
Tingting Jin, Peipei Wang, Xiubing Long, Kailong Jiang, Pinrao Song, Wenbiao Wu, Gaoya Xu, Yubo Zhou, Jia Li, Tao Liu
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia. ChemMedChem 16 (9) (2021)
Lexian Tong, Xuemei Li, Yongzhou Hu, Tao Liu
Recent advances in FLT3 inhibitors for acute myeloid leukemia. Future medicinal chemistry 12 (10) (2020)
Daqiang Li, Xiaotuan Zhang, Xiaodong Ma, Lei Xu, Jianjun Yu, Lixin Gao, Xiaobei Hu, Jiankang Zhang, Xiaowu Dong, Jia Li, Tao Liu, Yubo Zhou, Yongzhou Hu
Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors. Journal of medicinal chemistry 61 (20) (2018)