Thomas A Leonard

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2023
Publications (10 Years): 16

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

The Journal of biological chemistry

BioEssays : news and reviews in molecular, cellular and developmental biology

Medizinische Universität Wien

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Medizinische Universität Wien Jan 01 2012

Austria

Principal Investigator :: Max F. Perutz Laboratories

National Institute of Diabetes and Digestive and Kidney Diseases Sep 27 2005 - Sep 27 2011

United States

Postdoctoral scientist :: Laboratory of Molecular Biology

Education History

University of Cambridge Oct 01 2001 - Sep 30 2005

United Kingdom

PHD :: MRC Laboratory of Molecular Biology

University of Bristol Sep 01 1998 - Jul 31 2001

United Kingdom

BSC

Publications

Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Ronja Reinhardt, Thomas A Leonard
A critical evaluation of protein kinase regulation by activation loop autophosphorylation. eLife 12 (2023)
Ronja Reinhardt, Kai Hirzel, Gisela Link, Stephan A Eisler, Tanja Hägele, Matthew A H Parson, John E Burke, Angelika Hausser, Thomas A Leonard
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis . Proceedings of the National Academy of Sciences of the United States of America 120 (7) (2023)
Aleksandra Levina, Kaelin D Fleming, John E Burke, Thomas A Leonard
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation. Nature communications 13 (1) (2022)
Linda Truebestein, Harald Hornegger, Dorothea Anrather, Markus Hartl, Kaelin D Fleming, Jordan T B Stariha, Els Pardon, Jan Steyaert, John E Burke, Thomas A Leonard
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation. Proceedings of the National Academy of Sciences of the United States of America 118 (33) (2021)
Ronja Reinhardt, Linda Truebestein, Heiko A Schmidt, Thomas A Leonard
It Takes Two to Tango: Activation of Protein Kinase D by Dimerization. BioEssays : news and reviews in molecular, cellular and developmental biology 42 (4) (2020)
Daniel J Elsner, Katharina M Siess, Thomas Gossenreiter, Markus Hartl, Thomas A Leonard
A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation. The Journal of biological chemistry 294 (39) (2019)
Katharina M Siess, Thomas A Leonard
Lipid-dependent Akt-ivity: where, when, and how. Biochemical Society transactions 47 (3) (2019)
Thomas A Leonard
Reply to Agarwal: Activity against nuclear substrates is not necessarily mediated by nuclear Akt. Proceedings of the National Academy of Sciences of the United States of America 115 (27) (2018)
Iva Lučić, Manoj K Rathinaswamy, Linda Truebestein, David J Hamelin, John E Burke, Thomas A Leonard
Conformational sampling of membranes by Akt controls its activation and inactivation. Proceedings of the National Academy of Sciences of the United States of America 115 (17) (2018)
Freia von Raußendorf, Anita de Ruiter, Thomas A Leonard
A switch in nucleotide affinity governs activation of the Src and Tec family kinases. Scientific reports 7 (1) (2017)
Linda Truebestein, Daniel J Elsner, Elisabeth Fuchs, Thomas A Leonard
A molecular ruler regulates cytoskeletal remodelling by the Rho kinases. Nature communications 6 (2015)

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Publication Activity (10 Years)

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Thomas A Leonard