Thomas R Cech

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Topics

Binding Protein

Gene Expression

Circulating Tumor

Top Venues

RNA (New York, N.Y.)

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Genes & development

This page only lists publications with an associated author ORCID identifier.

Publications

Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) 30 (9) (2024)
Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) 30 (9) (2024)
Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) 30 (9) (2024)
Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) 30 (9) (2024)
Jiarui Song, Liqi Yao, Anne R Gooding, Valentin Thron, Vignesh Kasinath, Thomas R Cech
Diverse RNA Structures Induce PRC2 Dimerization and Inhibit Histone Methyltransferase Activity. bioRxiv : the preprint server for biology (2024)
Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) 30 (9) (2024)
Kaitlin Johnson, Julia M Seidel, Thomas R Cech
Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA (New York, N.Y.) (2024)
Wayne O Hemphill, Calvin K Voong, Regan Fenske, James A Goodrich, Thomas R Cech
Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search. Proceedings of the National Academy of Sciences of the United States of America 120 (26) (2023)
Wayne O Hemphill, Regan Fenske, Anne R Gooding, Thomas R Cech
PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers. Proceedings of the National Academy of Sciences of the United States of America 120 (23) (2023)
Jiarui Song, Anne R Gooding, Wayne O Hemphill, Brittney D Love, Anne Robertson, Liqi Yao, Leonard I Zon, Trista E North, Vignesh Kasinath, Thomas R Cech
Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science (New York, N.Y.) 381 (6664) (2023)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Arthur J Zaug, Karen J Goodrich, Jessica J Song, Ashley E Sullivan, Thomas R Cech
Reconstitution of a telomeric replicon organized by CST. Nature 608 (7924) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Linnea I Jansson-Fritzberg, Camila I Sousa, Michael J Smallegan, Jessica J Song, Anne R Gooding, Vignesh Kasinath, John L Rinn, Thomas R Cech
DNMT1 inhibition by pUG-fold quadruplex RNA. RNA (New York, N.Y.) 29 (3) (2022)
Katerina Kraft, Kathryn E Yost, Sedona E Murphy, Andreas Magg, Yicheng Long, M Ryan Corces, Jeffrey M Granja, Lars Wittler, Stefan Mundlos, Thomas R Cech, Alistair N Boettiger, Howard Y Chang
Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proceedings of the National Academy of Sciences of the United States of America 119 (22) (2022)
Neeraj Agarwal, Sebastien Rinaldetti, Bassem B Cheikh, Qiong Zhou, Evan P Hass, Robert T Jones, Molishree Joshi, Daniel V LaBarbera, Simon R V Knott, Thomas R Cech, Dan Theodorescu
TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer. Proceedings of the National Academy of Sciences of the United States of America 118 (38) (2021)
Ci Ji Lim, Thomas R Cech
Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization. Nature reviews. Molecular cell biology 22 (4) (2021)
Gabrijela Dumbović, Ulrich Braunschweig, Heera K Langner, Michael J Smallegan, Josep Biayna, Evan P Hass, Katarzyna Jastrzebska, Benjamin J Blencowe, Thomas R Cech, Marvin H Caruthers, John L Rinn
Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nature communications 12 (1) (2021)
Gabrijela Dumbović, Ulrich Braunschweig, Heera K Langner, Michael J Smallegan, Josep Biayna, Evan P Hass, Katarzyna Jastrzebska, Benjamin J Blencowe, Thomas R Cech, Marvin H Caruthers, John L Rinn
Publisher Correction: Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nature communications 12 (1) (2021)
Josh Lewis Stern, Grace N Hibshman, Kevin Hu, Sarah E Ferrara, James C Costello, Jong Wook Kim, Pablo Tamayo, Thomas R Cech, Franklin W Huang
Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Molecular cancer research : MCR 18 (7) (2020)
Teisha J Rowland, Andrew J Bonham, Thomas R Cech
Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers. Molecular oncology 14 (10) (2020)
Ci Ji Lim, Alexandra T Barbour, Arthur J Zaug, Karen J Goodrich, Allison E McKay, Deborah S Wuttke, Thomas R Cech
The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science (New York, N.Y.) 368 (6495) (2020)
Yicheng Long, Taeyoung Hwang, Anne R Gooding, Karen J Goodrich, John L Rinn, Thomas R Cech
RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells. Nature genetics 52 (9) (2020)
Xueyin Wang, Yicheng Long, Richard D Paucek, Anne R Gooding, Thomas Lee, Rachel M Burdorf, Thomas R Cech
Regulation of histone methylation by automethylation of PRC2. Genes & development 33 (19-20) (2019)
Teisha J Rowland, Gabrijela Dumbović, Evan P Hass, John L Rinn, Thomas R Cech
Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines. Proceedings of the National Academy of Sciences of the United States of America 116 (37) (2019)
Daniel T Youmans, Jens C Schmidt, Thomas R Cech
Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits. Genes & development 32 (11-12) (2018)
Yicheng Long, Xueyin Wang, Daniel T Youmans, Thomas R Cech
How do lncRNAs regulate transcription? Science advances 3 (9) (2017)
Yicheng Long, Ben Bolanos, Lihu Gong, Wei Liu, Karen J Goodrich, Xin Yang, Siming Chen, Anne R Gooding, Karen A Maegley, Ketan S Gajiwala, Alexei Brooun, Thomas R Cech, Xin Liu
Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2. eLife 6 (2017)
Ci Ji Lim, Arthur J Zaug, Hee Jin Kim, Thomas R Cech
Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity. Nature communications 8 (1) (2017)
Xueyin Wang, Richard D Paucek, Anne R Gooding, Zachary Z Brown, Eva J Ge, Tom W Muir, Thomas R Cech
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nature structural & molecular biology 24 (12) (2017)