Tilo Kunath

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 24

Top Venues

Scientific reports

The European journal of neuroscience

Nature communications

Cell death and differentiation

University of Edinburgh

University of Toronto (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Edinburgh Jan 01 2007

United Kingdom

Reader in Regenerative Neurobiology :: MRC Centre for Regenerative Medicine

Education History

University of Toronto

Canada

PHD :: Molecular and Medical Genetics

Publications

Alexandre Chappard, Craig Leighton, Rebecca S Saleeb, Kiani Jeacock, Sarah R Ball, Katie Morris, Owen Kantelberg, Ji-Eun Lee, Elsa Zacco, Annalisa Pastore, Margaret Sunde, David J Clarke, Patrick Downey, Tilo Kunath, Mathew H Horrocks
Single-Molecule Two-Color Coincidence Detection of Unlabeled alpha-Synuclein Aggregates. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (15) (2023)
Rebecca S Saleeb, Craig Leighton, Ji-Eun Lee, Judi O'Shaughnessy, Kiani Jeacock, Alexandre Chappard, Robyn Cumberland, Tianxiao Zhao, Sarah R Ball, Margaret Sunde, David James Clark, Kristin Piché, Jacob A McPhail, Ariel Louwrier, Rachel Angers, Sonia Gandhi, Patrick Downey, Tilo Kunath, Mathew H Horrocks
Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates. Science advances 9 (46) (2023)
Alexandre Chappard, Craig Leighton, Rebecca S Saleeb, Kiani Jeacock, Sarah R Ball, Katie Morris, Owen Kantelberg, Ji-Eun Lee, Elsa Zacco, Annalisa Pastore, Margaret Sunde, David J Clarke, Patrick Downey, Tilo Kunath, Mathew H Horrocks
Single-Molecule Two-Color Coincidence Detection of Unlabeled alpha-Synuclein Aggregates. Angewandte Chemie (International ed. in English) (2023)
Alexandre Chappard, Craig Leighton, Rebecca S Saleeb, Kiani Jeacock, Sarah R Ball, Katie Morris, Owen Kantelberg, Ji-Eun Lee, Elsa Zacco, Annalisa Pastore, Margaret Sunde, David J Clarke, Patrick Downey, Tilo Kunath, Mathew H Horrocks
Single-Molecule Two-Color Coincidence Detection of Unlabeled alpha-Synuclein Aggregates. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (15) (2023)
Brendan Monogue, Yixi Chen, Hadrian Sparks, Ranya Behbehani, Andrew Chai, Alexander J Rajic, Aaron Massey, B K Kleinschmidt-Demasters, Matthieu Vermeren, Tilo Kunath, J David Beckham
Alpha-synuclein supports type 1 interferon signalling in neurons and brain tissue. Brain : a journal of neurology 145 (10) (2022)
Minee L Choi, Alexandre Chappard, Bhanu P Singh, Catherine Maclachlan, Margarida Rodrigues, Evgeniya I Fedotova, Alexey V Berezhnov, Suman De, Christopher J Peddie, Dilan Athauda, Gurvir S Virdi, Weijia Zhang, James R Evans, Anna I Wernick, Zeinab Shadman Zanjani, Plamena R Angelova, Noemí Esteras, Andrey Y Vinokurov, Katie Morris, Kiani Jeacock, Laura Tosatto, Daniel Little, Paul Gissen, David James Clark, Tilo Kunath, Lucy Collinson, David Klenerman, Andrey Y Abramov, Mathew H Horrocks, Sonia Gandhi
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity. Nature neuroscience 25 (9) (2022)
Gurvir S Virdi, Minee L Choi, James R Evans, Zhi Yao, Dilan Athauda, Stephanie Strohbuecker, Raja S Nirujogi, Anna I Wernick, Noelia Pelegrina-Hidalgo, Craig Leighton, Rebecca S Saleeb, Olga Kopach, Haya Alrashidi, Daniela Melandri, Jimena Perez-Lloret, Plamena R Angelova, Sergiy Sylantyev, Simon Eaton, Simon Heales, Dmitri A Rusakov, Dario R Alessi, Tilo Kunath, Mathew H Horrocks, Andrey Y Abramov, Rickie Patani, Sonia Gandhi
Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson's disease in midbrain dopaminergic neurons. NPJ Parkinson's disease 8 (1) (2022)
Nguyen-Vi Mohamed, Julien Sirois, Janani Ramamurthy, Meghna Mathur, Paula Lépine, Eric Deneault, Gilles Maussion, Michael Nicouleau, Carol X-Q Chen, Narges Abdian, Vincent Soubannier, Eddie Cai, Harris Nami, Rhalena A Thomas, Dingke Wen, Mahdieh Tabatabaei, Lenore K Beitel, Karamjit Singh Dolt, Jason Karamchandani, Jo Anne Stratton, Tilo Kunath, Edward A Fon, Thomas M Durcan
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy. Brain communications 3 (4) (2021)
Eleanor Sinclair, Drupad K Trivedi, Depanjan Sarkar, Caitlin Walton-Doyle, Joy Milne, Tilo Kunath, Anouk M Rijs, Rob M A de Bie, Royston Goodacre, Monty Silverdale, Perdita E Barran
Metabolomics of sebum reveals lipid dysregulation in Parkinson's disease. Nature communications 12 (1) (2021)
Yixi Chen, Tilo Kunath, Joanna P Simpson, Natalie Z M Homer, Sergiy Sylantyev
Synaptic signalling in a network of dopamine neurons: what prevents proper intercellular crosstalk? FEBS letters 594 (20) (2020)
Plamena R Angelova, Minee L Choi, Alexey V Berezhnov, Mathew H Horrocks, Craig D Hughes, Suman De, Margarida Rodrigues, Ratsuda Yapom, Daniel Little, Karamjit S Dolt, Tilo Kunath, Michael J Devine, Paul Gissen, Mikhail S Shchepinov, Sergiy Sylantyev, Evgeny V Pavlov, David Klenerman, Andrey Y Abramov, Sonia Gandhi
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation. Cell death and differentiation (2020)
Plamena R Angelova, Minee L Choi, Alexey V Berezhnov, Mathew H Horrocks, Craig D Hughes, Suman De, Margarida Rodrigues, Ratsuda Yapom, Daniel Little, Karamjit S Dolt, Tilo Kunath, Michael J Devine, Paul Gissen, Mikhail S Shchepinov, Sergiy Sylantyev, Evgeny V Pavlov, David Klenerman, Andrey Y Abramov, Sonia Gandhi
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation. Cell death and differentiation 27 (10) (2020)
Tilo Kunath, Ammar Natalwala, Claire Chan, Yixi Chen, Benjamin Stecher, Martin Taylor, Sadaquate Khan, Miratul M K Muqit
Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies? The European journal of neuroscience 49 (4) (2019)
Karamjit Singh Dolt, Fella Hammachi, Tilo Kunath
Modeling Parkinson's disease with induced pluripotent stem cells harboring α-synuclein mutations. Brain pathology (Zurich, Switzerland) 27 (4) (2018)
Marthe H R Ludtmann, Plamena R Angelova, Mathew H Horrocks, Minee L Choi, Margarida Rodrigues, Artyom Y Baev, Alexey V Berezhnov, Zhi Yao, Daniel Little, Blerida Banushi, Afnan Saleh Al-Menhali, Rohan T Ranasinghe, Daniel R Whiten, Ratsuda Yapom, Karamjit Singh Dolt, Michael J Devine, Paul Gissen, Tilo Kunath, Morana Jaganjac, Evgeny V Pavlov, David Klenerman, Andrey Y Abramov, Sonia Gandhi
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nature communications 9 (1) (2018)
Yixi Chen, Karamjit Singh Dolt, Marco Kriek, Terry Baker, Patrick Downey, Nicola J Drummond, Maurice A Canham, Ammar Natalwala, Susan Rosser, Tilo Kunath
Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene. The European journal of neuroscience 49 (4) (2018)
Fergus S McWhinnie, Kristel Sepp, Charlotte Wilson, Tilo Kunath, Theodore Hupp, Terry S Baker, Douglas R Houston, Alison N Hulme
Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (9) (2018)
Miriam A Vogt, Zahra Ehsaei, Philip Knuckles, Adrian Higginbottom, Michaela S Helmbrecht, Tilo Kunath, Kevin Eggan, Luis A Williams, Pamela J Shaw, Wolfgang Wurst, Thomas Floss, Andrea B Huber, Verdon Taylor
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons. Scientific reports 8 (1) (2018)
Ginetta Collo, Laura Cavalleri, Federica Bono, Cristina Mora, Stefania Fedele, Roberto William Invernizzi, Massimo Gennarelli, Giovanna Piovani, Tilo Kunath, Mark J Millan, Emilio Merlo Pich, PierFranco Spano
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling. Neural plasticity 2018 (2018)
Keiko Imamura, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean-Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryosuke Takahashi, Shinya Yamanaka, Haruhisa Inoue
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science translational medicine 9 (391) (2018)
Takuya Azami, Tsuyoshi Waku, Ken Matsumoto, Hyojung Jeon, Masafumi Muratani, Akihiro Kawashima, Jun Yanagisawa, Ichiro Manabe, Ryozo Nagai, Tilo Kunath, Tomonori Nakamura, Kazuki Kurimoto, Mitinori Saitou, Satoru Takahashi, Masatsugu Ema
Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4. Development (Cambridge, England) 144 (20) (2017)
Stefania Fedele, Ginetta Collo, Katharina Behr, Josef Bischofberger, Stephan Müller, Tilo Kunath, Klaus Christensen, Anna Lisa Gündner, Martin Graf, Ravi Jagasia, Verdon Taylor
Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential. Scientific reports 7 (1) (2017)
Nicola J Drummond, Nick O Davies, Janet E Lovett, Mark R Miller, Graeme Cook, Thomas Becker, Catherina G Becker, Donald B McPhail, Tilo Kunath
A synthetic cell permeable antioxidant protects neurons against acute oxidative stress. Scientific reports 7 (1) (2017)
Iván Velasco, Tilo Kunath, Verónica Ramos-Mejía, Marco Antonio Velasco Velazquez
Producing Stem Cell-Based Transplants for Future Therapeutic Purposes. Stem cells international 2017 (2017)

Tilo Kunath.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Tilo Kunath