Timothy J Purwin

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 15

Top Topics

Top Venues

Science signaling

Molecular cancer research : MCR

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Vivian Chua, Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka, Usman Baqai, Timothy J Purwin, Jelan I Haj, Francis J Waltrich, Isabella V Trachtenberg, Kristine Luo, Rohith Tudi, Angela Jeon, Anna Han, Inna Chervoneva, Michael A Davies, Julio A Aguirre-Ghiso, Takami Sato, Andrew E Aplin
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science signaling 17 (840) (2024)
Vivian Chua, Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka, Usman Baqai, Timothy J Purwin, Jelan I Haj, Francis J Waltrich, Isabella V Trachtenberg, Kristine Luo, Rohith Tudi, Angela Jeon, Anna Han, Inna Chervoneva, Michael A Davies, Julio A Aguirre-Ghiso, Takami Sato, Andrew E Aplin
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science signaling 17 (840) (2024)
Vivian Chua, Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka, Usman Baqai, Timothy J Purwin, Jelan I Haj, Francis J Waltrich, Isabella V Trachtenberg, Kristine Luo, Rohith Tudi, Angela Jeon, Anna Han, Inna Chervoneva, Michael A Davies, Julio A Aguirre-Ghiso, Takami Sato, Andrew E Aplin
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science signaling 17 (840) (2024)
Vivian Chua, Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka, Usman Baqai, Timothy J Purwin, Jelan I Haj, Francis J Waltrich, Isabella V Trachtenberg, Kristine Luo, Rohith Tudi, Angela Jeon, Anna Han, Inna Chervoneva, Michael A Davies, Julio A Aguirre-Ghiso, Takami Sato, Andrew E Aplin
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. Science signaling 17 (840) (2024)
Sheera R Rosenbaum, Signe Caksa, Casey D Stefanski, Isabella V Trachtenberg, Haley P Wilson, Nicole A Wilski, Connor A Ott, Timothy J Purwin, Jelan I Haj, Danielle Pomante, Daniel Kotas, Inna Chervoneva, Claudia Capparelli, Andrew E Aplin
SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death. Molecular cancer research : MCR (2023)
Anna Han, Vivian Chua, Usman Baqai, Timothy J Purwin, Nelisa Bechtel, Emily Hunter, Manoela Tiago, Erin Seifert, David W Speicher, Zachary T Schug, J William Harbour, Andrew E Aplin
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma. Oncogene 41 (8) (2022)
Claudia Capparelli, Timothy J Purwin, McKenna Q Glasheen, Signe Caksa, Manoela Tiago, Nicole A Wilski, Danielle Pomante, Sheera Rosenbaum, Mai Q Nguyen, Weijia Cai, Janusz Franco-Barraza, Richard Zheng, Gaurav Kumar, Inna Chervoneva, Ayako Shimada, Vito W Rebecca, Adam E Snook, Kim Hookim, Xiaowei Xu, Edna Cukierman, Meenhard Herylyn, Andrew E Aplin
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma. Nature communications 13 (1) (2022)
Weijia Cai, Mai Q Nguyen, Nicole A Wilski, Timothy J Purwin, Megane Vernon, Manoela Tiago, Andrew E Aplin
A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors in NRAS Mutant Melanoma. Cancer research 82 (14) (2022)
Usman Baqai, Timothy J Purwin, Nelisa Bechtel, Vivian Chua, Anna Han, Edward J Hartsough, Jeffim N Kuznetsov, J William Harbour, Andrew E Aplin
Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma. Molecular cancer research : MCR 20 (8) (2022)
Anna Han, Timothy J Purwin, Andrew E Aplin
Roles of the BAP1 Tumor Suppressor in Cell Metabolism. Cancer research 81 (11) (2021)
Jessica L F Teh, Timothy J Purwin, Anna Han, Vivian Chua, Prem Patel, Usman Baqai, Connie Liao, Nelisa Bechtel, Takami Sato, Michael A Davies, Julio Aguirre-Ghiso, Andrew E Aplin
Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma. Molecular cancer therapeutics 19 (8) (2020)
Anna Han, Timothy J Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin Seifert, Takami Sato, Zachary T Schug, David W Speicher, J William Harbour, Andrew E Aplin
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors. Oncogene 40 (3) (2020)
Dan A Erkes, Weijia Cai, Ileine M Sanchez, Timothy J Purwin, Corey Rogers, Conroy O Field, Adam C Berger, Edward J Hartsough, Ulrich Rodeck, Emad S Alnemri, Andrew E Aplin
Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis. Cancer discovery 10 (2) (2019)
Ileine M Sanchez, Timothy J Purwin, Inna Chervoneva, Dan A Erkes, Mai Q Nguyen, Michael A Davies, Katherine L Nathanson, Kristel Kemper, Daniel S Peeper, Andrew E Aplin
In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma. Molecular cancer therapeutics 18 (9) (2019)
Nicole A Wilski, Christina Del Casale, Timothy J Purwin, Andrew E Aplin, Christopher M Snyder
Murine Cytomegalovirus Infection of Melanoma Lesions Delays Tumor Growth by Recruiting and Repolarizing Monocytic Phagocytes in the Tumor. Journal of virology 93 (20) (2019)