Your account is not claimed yet. You can sign up with ORCID to claim your account.

Meenhard Herlyn

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 31

Top Venues

Nature communications

Cancer research communications

Nature

Cancer research

Wistar Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Wistar Institute Jan 1o 1978

United States

Professor, Director :: Melanoma Research Center

Publications

Simona Lombardi, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Heng Liu, Wei Zhou, Meenhard Herlyn, Jianhuang Lin, Rugang Zhang
Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer research communications 3 (6) (2023)
Vito Rebecca, Kasturee Jagirdar, Marie Portuallo, Meihan Wei, Matthew Wilhide, Jeremy Bravo, Bailey Robertson, Gretchen Alicea, Crsytal Aguh, Min Xiao, Tetiana Godok, Dylan Fingerman, Gregory Brown, Meenhard Herlyn, Brian Guo, Eneda Toska, Daniel J Zabransky, Bradley Wubbenhorst, Katherine L Nathanson, Shawn Kwatra, Yogesh Goyal, Hongkai Ji, Jingjing Liu
ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma. Research square (2023)
Simona Lombardi, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Heng Liu, Wei Zhou, Meenhard Herlyn, Jianhuang Lin, Rugang Zhang
Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer research communications 3 (6) (2023)
Simona Lombardi, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Heng Liu, Wei Zhou, Meenhard Herlyn, Jianhuang Lin, Rugang Zhang
Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer research communications 3 (6) (2023)
Vito Rebecca, Kasturee Jagirdar, Marie Portuallo, Meihan Wei, Matthew Wilhide, Jeremy Bravo, Bailey Robertson, Gretchen Alicea, Crsytal Aguh, Min Xiao, Tetiana Godok, Dylan Fingerman, Gregory Brown, Meenhard Herlyn, Brian Guo, Eneda Toska, Daniel J Zabransky, Bradley Wubbenhorst, Katherine L Nathanson, Shawn Kwatra, Yogesh Goyal, Hongkai Ji, Jingjing Liu
ERK Hyperactivation Serves as a Unified Mechanism of Escape in Intrinsic and Acquired CDK4/6 Inhibitor Resistance in Acral Lentiginous Melanoma. Research square (2023)
Wei Guo, Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, Xiaowei Xu, Meenhard Herlyn, Carl H June, Ellen Puré
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, Xiaowei Xu, Meenhard Herlyn, Carl H June, Ellen Puré, Wei Guo
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Wenqun Zhong, Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu, Yumei Li, Neil C Sheppard, Serge Y Fuchs, Xiaowei Xu, Meenhard Herlyn, Carl H June, Ellen Puré, Wei Guo
Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer research (2023)
Sergii Domanskyi, Anuj Srivastava, Jessica Kaster, Haiyin Li, Meenhard Herlyn, Jill C Rubinstein, Jeffrey H Chuang
Nextflow Pipeline for Visium and H&E Data from Patient-Derived Xenograft Samples. bioRxiv : the preprint server for biology (2023)
Simona Lombardi, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Heng Liu, Wei Zhou, Meenhard Herlyn, Jianhuang Lin, Rugang Zhang
Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer research communications 3 (6) (2023)
McKenna Q Glasheen, Signe Caksa, Amelia G Young, Nicole A Wilski, Connor A Ott, Inna Chervoneva, Keith T Flaherty, Meenhard Herlyn, Xiaowei Xu, Andrew E Aplin, Claudia Capparelli
Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma. Molecular cancer therapeutics (2023)
Yogesh Goyal, Gianna T Busch, Maalavika Pillai, Jingxin Li, Ryan H Boe, Emanuelle I Grody, Manoj Chelvanambi, Ian P Dardani, Benjamin Emert, Nicholas Bodkin, Jonas Braun, Dylan Fingerman, Amanpreet Kaur, Naveen Jain, Pavithran T Ravindran, Ian A Mellis, Karun Kiani, Gretchen M Alicea, Mitchell E Fane, Syeda Subia Ahmed, Haiyin Li, Yeqing Chen, Cedric Chai, Jessica Kaster, Russell G Witt, Rossana Lazcano, Davis R Ingram, Sarah B Johnson, Khalida Wani, Margaret C Dunagin, Alexander J Lazar, Ashani T Weeraratna, Jennifer A Wargo, Meenhard Herlyn, Arjun Raj
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells. Nature (2023)
Simona Lombardi, Aaron R Goldman, Hsin-Yao Tang, Andrew V Kossenkov, Heng Liu, Wei Zhou, Meenhard Herlyn, Jianhuang Lin, Rugang Zhang
Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer research communications 3 (6) (2023)
Hyungsoo Kim, Yongmei Feng, Rabi Murad, Joanna Pozniak, Carl Pelz, Yeqing Chen, Bhavik Dalal, Rosalie C Sears, Eduard Sergienko, Michael Jackson, Eytan Ruppin, Meenhard Herlyn, Curtis C Harris, Jean-Christophe Marine, Victoria Klepsch, Gottfried Baier, Ze'ev A Ronai
Melanoma-intrinsic NR2F6 activity regulates antitumor immunity. Science advances 9 (27) (2023)
Ian P Dardani, Benjamin L Emert, Yogesh Goyal, Connie L Jiang, Amanpreet Kaur, Jasmine Lee, Sara H Rouhanifard, Gretchen M Alicea, Mitchell E Fane, Min Xiao, Meenhard Herlyn, Ashani T Weeraratna, Arjun Raj
ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ. Nature methods 19 (11) (2022)
Claudia Capparelli, Timothy J Purwin, McKenna Q Glasheen, Signe Caksa, Manoela Tiago, Nicole A Wilski, Danielle Pomante, Sheera Rosenbaum, Mai Q Nguyen, Weijia Cai, Janusz Franco-Barraza, Richard Zheng, Gaurav Kumar, Inna Chervoneva, Ayako Shimada, Vito W Rebecca, Adam E Snook, Kim Hookim, Xiaowei Xu, Edna Cukierman, Meenhard Herlyn, Andrew E Aplin
Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma. Nature communications 13 (1) (2022)
Heike Chauvistré, Batool Shannan, Sheena M Daignault-Mill, Robert J Ju, Daniel Picard, Stefanie Egetemaier, Renata Varaljai, Christine S Gibhardt, Antonio Sechi, Farnusch Kaschani, Oliver Keminer, Samantha J Stehbens, Jingjing Liu, Xiangfan Yin, Kirujan Jeyakumar, Felix C E Vogel, Clemens Krepler, Vito W Rebecca, Linda Kubat, Smiths S Lueong, Jan Forster, Susanne Horn, Marc Remke, Michael Ehrmann, Annette Paschen, Jürgen Christian Becker, Iris Helfrich, Daniel Rauh, Markus Kaiser, Sheraz Gul, Meenhard Herlyn, Ivan Bogeski, José Neptuno Rodríguez-López, Nikolas K Haass, Dirk Schadendorf, Alexander Roesch
Persister state-directed transitioning and vulnerability in melanoma. Nature communications 13 (1) (2022)
Hua Sun, Song Cao, R Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C Wendl, Sherri R Davies, Matthew H Bailey, Tina M Primeau, Jeremy Hoog, Jacqueline L Mudd, Dennis A Dean, Rajesh Patidar, Li Chen, Matthew A Wyczalkowski, Reyka G Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian Andrew Van Tine, Cynthia X Ma, Rebecca Aft, Katherine C Fuh, Julie K Schwarz, Jose P Zevallos, Sidharth V Puram, John F Dipersio, null null, Brandi Davis-Dusenbery, Matthew J Ellis, Michael T Lewis, Michael A Davies, Meenhard Herlyn, Bingliang Fang, Jack A Roth, Alana L Welm, Bryan E Welm, Funda Meric-Bernstam, Feng Chen, Ryan C Fields, Shunqiang Li, Ramaswamy Govindan, James H Doroshow, Jeffrey A Moscow, Yvonne A Evrard, Jeffrey H Chuang, Benjamin J Raphael, Li Ding
Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nature communications 13 (1) (2022)
Vaibhav Jain, Sandra L Harper, Amanda M Versace, Dylan Fingerman, Gregory Schuyler Brown, Monika Bhardwaj, Mary Ann S Crissey, Aaron R Goldman, Gordon Ruthel, Jingjing Liu, Aleksandra Zivkovic, Holger Stark, Meenhard Herlyn, Phyllis A Gimotty, David W Speicher, Ravi K Amaravadi
Targeting UGCG overcomes resistance to lysosomal autophagy inhibition. Cancer discovery (2022)
Lei Guan, Bin Wu, Ting Li, Lynn A Beer, Gaurav Sharma, Mingyue Li, Chin Nien Lee, Shujing Liu, Changsong Yang, Lili Huang, Dennie T Frederick, Genevieve M Boland, Guangcan Shao, Tatyana M Svitkina, Kathy Q Cai, Fangping Chen, Meng-Qiu Dong, Gordon B Mills, Lynn M Schuchter, Giorgos C Karakousis, Tara C Mitchell, Keith T Flaherty, David W Speicher, Youhai H Chen, Meenhard Herlyn, Ravi K Amaravadi, Xiaowei Xu, Wei Guo
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8 + T-cell infiltration into tumors. Nature communications 13 (1) (2022)
Mitchell E Fane, Yash Chhabra, Gretchen M Alicea, Devon A Maranto, Stephen M Douglass, Marie R Webster, Vito W Rebecca, Gloria E Marino, Filipe Almeida, Brett L Ecker, Daniel J Zabransky, Laura Hüser, Thomas Beer, Hsin-Yao Tang, Andrew Kossenkov, Meenhard Herlyn, David W Speicher, Wei Xu, Xiaowei Xu, Elizabeth D Thompson, Julio A Aguirre-Ghiso, Ashani T Weeraratna
Stromal changes in the aged lung induce an emergence from melanoma dormancy. Nature 606 (7913) (2022)
Alexander Schäfer, Benedicte Haenig, Julie Erupathil, Panja Strickner, Daniela Sabato, Richard W D Welford, Lhéanna Klaeylé, Elise Simon, Clemens Krepler, Patricia Brafford, Min Xiao, Meenhard Herlyn, Matthias Gstaiger, Francois Lehembre, Imke Renz
Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma. Oncogene 40 (9) (2021)
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Rajesh Patidar, Li Chen, Sandra Scherer, Matthew H Bailey, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Yuanxin Xi, Jing Wang, Jayamanna Wickramasinghe, Andrew V Kossenkov, Vito W Rebecca, Hua Sun, R Jay Mashl, Sherri R Davies, Ryan Jeon, Christian Frech, Jelena Randjelovic, Jacqueline Rosains, Francesco Galimi, Andrea Bertotti, Adam Lafferty, Alice C O'Farrell, Elodie Modave, Diether Lambrechts, Petra Ter Brugge, Violeta Serra, Elisabetta Marangoni, Rania El Botty, Hyunsoo Kim, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A Dean, Brandi Davis-Dusenbery, Yvonne A Evrard, James H Doroshow, Alana L Welm, Bryan E Welm, Michael T Lewis, Bingliang Fang, Jack A Roth, Funda Meric-Bernstam, Meenhard Herlyn, Michael A Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Claudio Isella, Jeffrey A Moscow, Livio Trusolino, Annette T Byrne, Jos Jonkers, Carol J Bult, Enzo Medico, Jeffrey H Chuang, null null, null null
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature genetics 53 (1) (2021)
Kuang Du, Shiyou Wei, Zhi Wei, Dennie T Frederick, Benchun Miao, Tabea Moll, Tian Tian, Eric Sugarman, Dmitry I Gabrilovich, Ryan J Sullivan, Lun-Xu Liu, Keith T Flaherty, Genevieve Marie Boland, Meenhard Herlyn, Gao Zhang
Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma. Nature communications 12 (1) (2021)
Hua Sun, Song Cao, R Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C Wendl, Sherri R Davies, Matthew H Bailey, Tina M Primeau, Jeremy Hoog, Jacqueline L Mudd, Dennis A Dean, Rajesh Patidar, Li Chen, Matthew A Wyczalkowski, Reyka G Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian Andrew Van Tine, Cynthia X Ma, Rebecca Aft, Katherine C Fuh, Julie K Schwarz, Jose P Zevallos, Sidharth V Puram, John F Dipersio, null null, Brandi Davis-Dusenbery, Matthew J Ellis, Michael T Lewis, Michael A Davies, Meenhard Herlyn, Bingliang Fang, Jack A Roth, Alana L Welm, Bryan E Welm, Funda Meric-Bernstam, Feng Chen, Ryan C Fields, Shunqiang Li, Ramaswamy Govindan, James H Doroshow, Jeffrey A Moscow, Yvonne A Evrard, Jeffrey H Chuang, Benjamin J Raphael, Li Ding
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nature communications 12 (1) (2021)
Beike Wang, Wei Zhang, Gao Zhang, Lawrence Kwong, Hezhe Lu, Jiufeng Tan, Norah Sadek, Min Xiao, Jie Zhang, Marilyne Labrie, Sergio Randell, Aurelie Beroard, Eric Sugarman, Vito W Rebecca, Zhi Wei, Yiling Lu, Gordon B Mills, Jeffrey Field, Jessie Villanueva, Xiaowei Xu, Meenhard Herlyn, Wei Guo
Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma. Oncogene 40 (37) (2021)
David Liu, Jia-Ren Lin, Emily J Robitschek, Gyulnara G Kasumova, Alex Heyde, Alvin Shi, Adam Kraya, Gao Zhang, Tabea Moll, Dennie T Frederick, Yu-An Chen, Shu Wang, Denis Schapiro, Li-Lun Ho, Kevin Bi, Avinash Sahu, Shaolin Mei, Benchun Miao, Tatyana Sharova, Christopher Alvarez-Breckenridge, Jackson H Stocking, Tommy Kim, Riley Fadden, Donald Lawrence, Mai P Hoang, Daniel P Cahill, Mohsen Malehmir, Martin A Nowak, Priscilla Kaliopi Brastianos, Christine G Lian, Eytan Ruppin, Benjamin Izar, Meenhard Herlyn, Eliezer Van Allen, Katherine L Nathanson, Keith T Flaherty, Ryan J Sullivan, Manolis Kellis, Peter K Sorger, Genevieve Marie Boland
Evolution of delayed resistance to immunotherapy in a melanoma responder. Nature medicine 27 (6) (2021)
Guixin Zhu, Meenhard Herlyn, Xiaolu Yang
TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination. Nature cell biology 23 (9) (2021)
Ishani Das, Huiqin Chen, Gianluca Maddalo, Rainer Tuominen, Vito W Rebecca, Meenhard Herlyn, Johan Hansson, Michael A Davies, Suzanne Egyhazi Brage
Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma. Cell death & disease 11 (10) (2020)
Kumar Sachin Singh, Rishabh Sharma, Poli Adi Narayana Reddy, Prashanthi Vonteddu, Madeline Good, Anjana Sundarrajan, Hyeree Choi, Kar Muthumani, Andrew Kossenkov, Aaron R Goldman, Hsin-Yao Tang, Maxim Totrov, Joel Cassel, Maureen E Murphy, Rajasekharan Somasundaram, Meenhard Herlyn, Joseph M Salvino, Farokh Dotiwala
IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance. Nature 589 (7843) (2020)
Joshua X Wang, Mizuho Fukunaga-Kalabis, Meenhard Herlyn
Crosstalk in skin: melanocytes, keratinocytes, stem cells, and melanoma. Journal of cell communication and signaling 10 (3) (2016)

Meenhard Herlyn.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Meenhard Herlyn