Trevor M Penning (Trevor Penning)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 47

Top Venues

Chemical research in toxicology

Endocrinology

International journal of molecular sciences

Cancer research communications

University of Pennsylvania

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania

United States

Professor :: Pharmacology, OB/GYN and Biochemistry & Biophysics

University of Pennsylvania

United States

Associate Professor :: Pharmacology and OB/GYN

University of Pennsylvania

United States

Assistant Professor :: Pharmacology

Publications

Trevor M Penning, Douglas F Covey
5β-Dihydrosteroids: Formation and Properties. International journal of molecular sciences 25 (16) (2024)
Trevor M Penning, Douglas F Covey
5β-Dihydrosteroids: Formation and Properties. International journal of molecular sciences 25 (16) (2024)
Ryan D Paulukinas, Trevor M Penning
Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes. Endocrinology (2023)
Andrea J Detlefsen, Clementina A Mesaros, Ling Duan, Trevor M Penning
AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol. Cancer research communications 3 (9) (2023)
Krishnaiah Maddeboina, Sravan K Jonnalagadda, Ahmed Morsy, Ling Duan, Yashpal S Chhonker, Daryl J Murry, Trevor M Penning, Paul C Trippier
Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model. Journal of medicinal chemistry (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology (2023)
Andrea J Detlefsen, Ryan D Paulukinas, Trevor M Penning
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. International journal of molecular sciences 24 (3) (2023)
Andrea J Detlefsen, Ryan D Paulukinas, Trevor M Penning
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. International journal of molecular sciences 24 (3) (2023)
Ryan D Paulukinas, Trevor M Penning
Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes. Endocrinology (2023)
Jason Garcia, Kirsten D Krieger, Candice Loitz, Lillian M Perez, Zachary A Richards, Yves Helou, Steven Kregel, Sasha Celada, Clementina A Mesaros, Maarten C Bosland, Peter H Gann, Thomas E Willnow, Donald J Vander Griend, Rick A Kittles, Gail S Prins, Trevor M Penning, Larisa Nonn
Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men. Cancer research communications 3 (3) (2023)
Ryan D Paulukinas, Trevor M Penning
Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes. Endocrinology 164 (5) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Jason Garcia, Kirsten D Krieger, Candice Loitz, Lillian M Perez, Zachary A Richards, Yves Helou, Steven Kregel, Sasha Celada, Clementina A Mesaros, Maarten C Bosland, Peter H Gann, Thomas E Willnow, Donald J Vander Griend, Rick A Kittles, Gail S Prins, Trevor M Penning, Larisa Nonn
Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men. Cancer research communications 3 (3) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology (2023)
Andrea J Detlefsen, Ryan D Paulukinas, Trevor M Penning
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. International journal of molecular sciences 24 (3) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Andrea J Detlefsen, Ryan D Paulukinas, Trevor M Penning
Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. International journal of molecular sciences 24 (3) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Jason Garcia, Kirsten D Krieger, Candice Loitz, Lillian M Perez, Zachary A Richards, Yves Helou, Steven Kregel, Sasha Celada, Clementina A Mesaros, Maarten C Bosland, Peter H Gann, Thomas E Willnow, Donald J Vander Griend, Rick A Kittles, Gail S Prins, Trevor M Penning, Larisa Nonn
Regulation of Prostate Androgens by Megalin and 25-hydroxyvitamin D Status: Mechanism for High Prostate Androgens in African American Men. Cancer research communications 3 (3) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Ryan D Paulukinas, Trevor M Penning
Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes. Endocrinology 164 (5) (2023)
Anthony L Su, Trevor M Penning
Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. Chemical research in toxicology 36 (2) (2023)
Trevor M Penning, Andrea J Detlefsen
Letter to the Editor from Penning and Deltefsen "Hydroxyeicosatetraenoic Acid Controls Androgen Reduction in Diverse Types of Human Epithelial Cells". Endocrinology (2023)
Holger Moustakas, Mihir S Date, Manoj Kumar, Terry W Schultz, Daniel C Liebler, Trevor M Penning, Daniel T Salvito, Anne Marie Api
An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects. Chemical research in toxicology (2022)
Lin Ma, Dongxiao Sun, Guangli Xiu, Philip Lazarus, Anil Vachani, Trevor M Penning, Alexander S Whitehead, Joshua E Muscat
Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer. International journal of environmental research and public health 19 (19) (2022)
Joseph D Romano, Yun Hao, Jason H Moore, Trevor M Penning
Automating Predictive Toxicology Using ComptoxAI. Chemical research in toxicology 35 (8) (2022)
Trevor M Penning, Anthony L Su, Karam El-Bayoumy
Nitroreduction: A Critical Metabolic Pathway for Drugs, Environmental Pollutants, and Explosives. Chemical research in toxicology 35 (10) (2022)
Laura L Gathercole, Nikolaos Nikolaou, Shelley E Harris, Anastasia Arvaniti, Toryn M Poolman, Jonathan M Hazlehurst, Denise V Kratschmar, Marijana Todorčević, Ahmad Moolla, Niall Dempster, Ryan C Pink, Michael F Saikali, Liz Bentley, Trevor M Penning, Claes Ohlsson, Carolyn L Cummins, Matti Poutanen, Alex Odermatt, Roger D Cox, Jeremy W Tomlinson
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype. The Journal of endocrinology 253 (3) (2022)
Anthony L Su, Clementina A Mesaros, Jacek Krzeminski, Karam El-Bayoumy, Trevor M Penning
Role of Human Aldo-Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene. Chemical research in toxicology (2022)
Ryan D Paulukinas, Clementina A Mesaros, Trevor M Penning
Conversion of Classical and 11-Oxygenated Androgens by Insulin-Induced AKR1C3 in a Model of Human PCOS Adipocytes. Endocrinology 163 (7) (2022)
Thomas P McKeon, Wei-Ting Hwang, Zhuoran Ding, Vicky Tam, Paul Wileyto, Karen Glanz, Trevor M Penning
Environmental exposomics and lung cancer risk assessment in the Philadelphia metropolitan area using ZIP code-level hazard indices. Environmental science and pollution research international 28 (24) (2021)
Nathan Appanna, Hylton Gibson, Elena Gangitano, Niall J Dempster, Karen Morris, Sherly George, Anastasia Arvaniti, Laura L Gathercole, Brian Keevil, Trevor M Penning, Karl-Heinz Storbeck, Jeremy W Tomlinson, Nikolaos Nikolaou
Differential activity and expression of human 5β-reductase (AKR1D1) splice variants. Journal of molecular endocrinology 66 (3) (2021)
Nuria Camiña, Trevor M Penning
Genetic and epigenetic regulation of the NRF2-KEAP1 pathway in human lung cancer. British journal of cancer (2021)
Isabelle Lee, Guannan Zhang, Clementina Mesaros, Trevor M Penning
Estrogen receptor-dependent and independent roles of benzo[a]pyrene in Ishikawa cells. The Journal of endocrinology 247 (2) (2021)
Angela Yaqian Zhu, Thomas P McKeon, Vicky Tam, Anil Vachani, Trevor M Penning, Wei-Ting Hwang
Geographic Differences in Lung Cancer Incidence: A Study of a Major Metropolitan Area within Southeastern Pennsylvania. International journal of environmental research and public health 17 (24) (2020)
Nikolaos Nikolaou, Anastasia Arvaniti, Nathan Appanna, Anna Sharp, Beverly A Hughes, Dena Digweed, Martin J Whitaker, Richard Ross, Wiebke Arlt, Trevor M Penning, Karen Morris, Sherly George, Brian G Keevil, Leanne Hodson, Laura L Gathercole, Jeremy W Tomlinson
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo. The Journal of endocrinology 245 (2) (2020)
Mihir S Date, Devin O'Brien, Danielle J Botelho, Terry W Schultz, Daniel C Liebler, Trevor M Penning, Daniel T Salvito
Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps. Chemical research in toxicology 33 (7) (2020)
Jessica R Murray, Clementina A Mesaros, Volker M Arlt, Albrecht Seidel, Ian A Blair, Trevor M Penning
Correction to "Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone". Chemical research in toxicology 32 (11) (2019)
Kshitij Verma, Tianzhu Zang, Trevor M Penning, Paul C Trippier
Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. Journal of medicinal chemistry 62 (7) (2019)
Jessica R Murray, Laureano de la Vega, John D Hayes, Ling Duan, Trevor M Penning
Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3-Nitrobenzanthrone in Human Lung Cells. Chemical research in toxicology 32 (12) (2019)
Jessica R Murray, Clementina A Mesaros, Volker M Arlt, Albrecht Seidel, Ian A Blair, Trevor M Penning
Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone. Chemical research in toxicology 31 (11) (2018)
Elahe A Mostaghel, Ailin Zhang, Susana Hernandez, Brett T Marck, Xiaotun Zhang, Daniel Tamae, Heather E Biehl, Maria Tretiakova, Jon Bartlett, John Burns, Ruth Dumpit, Lisa Ang, Alvin M Matsumoto, Trevor M Penning, Steven P Balk, Colm Morrissey, Eva Corey, Lawrence D True, Peter S Nelson
Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (1) (2018)
Kshitij Verma, Nehal Gupta, Tianzhu Zang, Phumvadee Wangtrakluldee, Sanjay K Srivastava, Trevor M Penning, Paul C Trippier
AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells. Molecular cancer therapeutics 17 (9) (2018)
Meng Huang, Clementina Mesaros, Linda C Hackfeld, Richard P Hodge, Ian A Blair, Trevor M Penning
Potential Metabolic Activation of Representative Alkylated Polycyclic Aromatic Hydrocarbons 1-Methylphenanthrene and 9-Ethylphenanthrene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells. Chemical research in toxicology 30 (12) (2017)
Meng Huang, Clementina Mesaros, Linda C Hackfeld, Richard P Hodge, Tianzhu Zang, Ian A Blair, Trevor M Penning
Potential Metabolic Activation of a Representative C4-Alkylated Polycyclic Aromatic Hydrocarbon Retene (1-Methyl-7-isopropyl-phenanthrene) Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells. Chemical research in toxicology 30 (4) (2017)
Trevor M Penning
Aldo-Keto Reductase Regulation by the Nrf2 System: Implications for Stress Response, Chemotherapy Drug Resistance, and Carcinogenesis. Chemical research in toxicology 30 (1) (2016)

Trevor M Penning.css-eqlu8i{font-size:small;padding-left:4px;} (Trevor Penning)

Publication Activity (10 Years)

Top Topics

Top Venues

Trevor M Penning (Trevor Penning)