Paul C Trippier

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 27

Top Venues

Journal of medicinal chemistry

ACS medicinal chemistry letters

ACS chemical neuroscience

Drug development research

University of Nebraska Medical Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Nebraska Medical Center Jul 01 2019

United States

Associate Professor :: Pharmaceutical Sciences

Texas Tech University Health Sciences Center School of Pharmacy Sep 01 2012 - Jun 30 2019

United States

Assistant Professor :: Pharmaceutical Sciences

Northwestern University Aug 01 2010 - Aug 01 2012

United States

Postdoctoral Research Fellow :: Chemistry

Cardiff University Dec 01 2008 - Aug 01 2010

United Kingdom

Postdoctoral Research Fellow :: Pharmacy

Publications

Md Shafikur Rahman, Shiva Hadi Esfahani, Yong Zhang, Aarfa Queen, Manar Aljarrah, Haya Kandil, Andrew Baez, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability. ACS medicinal chemistry letters 15 (4) (2024)
Angelica V Carmona, Shirisha Jonnalagadda, Alfie M Case, Krishnaiah Maddeboina, Sravan K Jonnalagadda, Louise F Dow, Ling Duan, Trevor M Penning, Paul C Trippier
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader. Communications chemistry 7 (1) (2024)
Md Shafikur Rahman, Shiva Hadi Esfahani, Yong Zhang, Aarfa Queen, Manar Aljarrah, Haya Kandil, Andrew Baez, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability. ACS medicinal chemistry letters 15 (4) (2024)
Md Shafikur Rahman, Shiva Hadi Esfahani, Yong Zhang, Aarfa Queen, Manar Aljarrah, Haya Kandil, Andrew Baez, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability. ACS medicinal chemistry letters 15 (4) (2024)
Md Shafikur Rahman, Shiva Hadi Esfahani, Yong Zhang, Aarfa Queen, Manar Aljarrah, Haya Kandil, Andrew Baez, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability. ACS medicinal chemistry letters 15 (4) (2024)
Angelica V Carmona, Shirisha Jonnalagadda, Alfie M Case, Krishnaiah Maddeboina, Sravan K Jonnalagadda, Louise F Dow, Ling Duan, Trevor M Penning, Paul C Trippier
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader. Communications chemistry 7 (1) (2024)
Louise F Dow, Alfie M Case, Megan P Paustian, Braeden R Pinkerton, Princess Simeon, Paul C Trippier
The evolution of small molecule enzyme activators. RSC medicinal chemistry 14 (11) (2023)
Krishnaiah Maddeboina, Sravan K Jonnalagadda, Ahmed Morsy, Ling Duan, Yashpal S Chhonker, Daryl J Murry, Trevor M Penning, Paul C Trippier
Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model. Journal of medicinal chemistry (2023)
Bader I Huwaimel, Sravan K Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentini, Claudiu T Supuran, Paul C Trippier
Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold. Drug development research (2023)
Bader I Huwaimel, Sravan K Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentini, Claudiu T Supuran, Paul C Trippier
Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold. Drug development research (2023)
Maria-Jesus Blanco, Amanda Bryant-Friedrich, Gunda I Georg, Amjad Ali, Paul L Ornstein, Lori Ferrins, Paul C Trippier
Excellence in Medicinal Chemistry: Celebrating ACS Medicinal Chemistry Division (MEDI) Awards. A Call for Nominations. ACS medicinal chemistry letters 14 (6) (2023)
Maria-Jesus Blanco, Amanda Bryant-Friedrich, Gunda I Georg, Amjad Ali, Paul L Ornstein, Lori Ferrins, Paul C Trippier
Excellence in Medicinal Chemistry: Celebrating ACS Medicinal Chemistry Division (MEDI) Awards. A Call for Nominations. Journal of medicinal chemistry (2023)
Md Ashraf-Uz-Zaman, Guangchen Ji, Dalton Tidwell, Linda Yin, Smathorn Thakolwiboon, Jie Pan, Riley Junell, Zach Griffin, Sadisna Shahi, Derek Barthels, Md Sanaullah Sajib, Paul C Trippier, Constantinos M Mikelis, Hiranmoy Das, Mirla Avila, Volker Neugebauer, Nadezhda A German
Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. ACS chemical neuroscience 13 (2) (2022)
Ahmed Morsy, Krishnaiah Maddeboina, Ju Gao, Hezhen Wang, Juan Valdez, Louise F Dow, Xinglong Wang, Paul C Trippier
Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction. ACS chemical neuroscience 13 (14) (2022)
Sravan K Jonnalagadda, Bader I Huwaimel, Shirisha Jonnalagadda, Jered C Garrison, Paul C Trippier
Access to Highly Strained Tricyclic Ketals Derived from Coumarins. The Journal of organic chemistry 87 (6) (2022)
Md Shafikur Rahman, Shikha Kumari, Shiva Hadi Esfahani, Saeideh Nozohouri, Srinidhi Jayaraman, Nihar Kinarivala, Joanna Kocot, Andrew Baez, Delaney Farris, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Correction to "Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability". Journal of medicinal chemistry 65 (1) (2021)
Ahmed Morsy, Angelica V Carmona, Paul C Trippier
Patient-Derived Induced Pluripotent Stem Cell Models for Phenotypic Screening in the Neuronal Ceroid Lipofuscinoses. Molecules (Basel, Switzerland) 26 (20) (2021)
Md Shafikur Rahman, Shikha Kumari, Shiva Hadi Esfahani, Saeideh Nozohouri, Srinidhi Jayaraman, Nihar Kinarivala, Joanna Kocot, Andrew Baez, Delaney Farris, Thomas J Abbruscato, Vardan T Karamyan, Paul C Trippier
Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability. Journal of medicinal chemistry 64 (17) (2021)
Bader I Huwaimel, Myla Bhakta, Chaitanya A Kulkarni, Alexander S Milliken, Feifei Wang, Aimin Peng, Paul S Brookes, Paul C Trippier
Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem 16 (7) (2021)
Mariateresa Giustiniano, Christian W Gruber, Caitlin N Kent, Paul C Trippier
Back to the Medicinal Chemistry Future. Journal of medicinal chemistry 64 (21) (2021)
Shikha Kumari, Angelica V Carmona, Amit K Tiwari, Paul C Trippier
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes. Journal of medicinal chemistry 63 (21) (2020)
Ahmed Morsy, Paul C Trippier
Reversal of Apalutamide and Darolutamide Aldo-Keto Reductase 1C3-Mediated Resistance by a Small Molecule Inhibitor. ACS chemical biology 15 (3) (2020)
Kshitij Verma, Tianzhu Zang, Trevor M Penning, Paul C Trippier
Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. Journal of medicinal chemistry 62 (7) (2019)
Ahmed Morsy, Paul C Trippier
Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry 62 (9) (2018)
Thomas J Abbruscato, Paul C Trippier
DARK Classics in Chemical Neuroscience: Methamphetamine. ACS chemical neuroscience 9 (10) (2018)
Nihar Kinarivala, Ronak Patel, Rose-Mary Boustany, Abraham Jacob Al-Ahmad, Paul C Trippier
Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2). Journal of medicinal chemistry 60 (23) (2017)
Hezhen Wang, Bader Huwaimel, Kshitij Verma, James Miller, Todd M Germain, Nihar Kinarivala, Dimitri Pappas, Paul S Brookes, Paul C Trippier
Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5. ChemMedChem 12 (13) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Paul C Trippier