William J Griffiths

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 22

Top Topics

Low Density Lipoprotein

Amyotrophic Lateral Sclerosis

Quality Control

Top Venues

Science advances

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

María Latorre-Leal, Patricia Rodriguez-Rodriguez, Luca Franchini, Orestis Nikolidakis, Makrina Daniilidou, Ljerka Delac, Mukesh K Varshney, Luis Enrique Arroyo-García, Francesca Eroli, Bengt Winblad, Kaj Blennow, Henrik Zetterberg, Miia Kivipelto, Manuela Pacciarini, Yuqin Wang, William J Griffiths, Ingemar Björkhem, Anna Sandebring-Matton, Ivan Nalvarte, Paula Merino-Serrais, Angel Cedazo-Mínguez, Silvia Maioli
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice. Science advances 10 (4) (2024)
María Latorre-Leal, Patricia Rodriguez-Rodriguez, Luca Franchini, Orestis Nikolidakis, Makrina Daniilidou, Ljerka Delac, Mukesh K Varshney, Luis Enrique Arroyo-García, Francesca Eroli, Bengt Winblad, Kaj Blennow, Henrik Zetterberg, Miia Kivipelto, Manuela Pacciarini, Yuqin Wang, William J Griffiths, Ingemar Björkhem, Anna Sandebring-Matton, Ivan Nalvarte, Paula Merino-Serrais, Angel Cedazo-Mínguez, Silvia Maioli
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice. Science advances 10 (4) (2024)
María Latorre-Leal, Patricia Rodriguez-Rodriguez, Luca Franchini, Orestis Nikolidakis, Makrina Daniilidou, Ljerka Delac, Mukesh K Varshney, Luis Enrique Arroyo-García, Francesca Eroli, Bengt Winblad, Kaj Blennow, Henrik Zetterberg, Miia Kivipelto, Manuela Pacciarini, Yuqin Wang, William J Griffiths, Ingemar Björkhem, Anna Sandebring-Matton, Ivan Nalvarte, Paula Merino-Serrais, Angel Cedazo-Mínguez, Silvia Maioli
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice. Science advances 10 (4) (2024)
María Latorre-Leal, Patricia Rodriguez-Rodriguez, Luca Franchini, Orestis Nikolidakis, Makrina Daniilidou, Ljerka Delac, Mukesh K Varshney, Luis Enrique Arroyo-García, Francesca Eroli, Bengt Winblad, Kaj Blennow, Henrik Zetterberg, Miia Kivipelto, Manuela Pacciarini, Yuqin Wang, William J Griffiths, Ingemar Björkhem, Anna Sandebring-Matton, Ivan Nalvarte, Paula Merino-Serrais, Angel Cedazo-Mínguez, Silvia Maioli
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice. Science advances 10 (4) (2024)
Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta. Open biology 13 (5) (2023)
Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta. Open biology 13 (5) (2023)
Matthew J Conroy, Robert M Andrews, Simon R Andrews, Lauren Cockayne, Edward A Dennis, Eoin Fahy, Caroline Gaud, William J Griffiths, Geoff Jukes, Maksim Kolchin, Karla Mendivelso, Andrea F Lopez-Clavijo, Caroline Ready, Shankar Subramaniam, Valerie B O'Donnell
LIPID MAPS: update to databases and tools for the lipidomics community. Nucleic acids research (2023)
Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta. Open biology 13 (5) (2023)
Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta. Open biology 13 (5) (2023)
Alison Dickson, Eylan Yutuc, Catherine A Thornton, James E Dunford, Udo Oppermann, Yuqin Wang, William J Griffiths
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta. Open biology 13 (5) (2023)
Ahmed Haider, Chunyu Zhao, Lu Wang, Zhiwei Xiao, Jian Rong, Xiaotian Xia, Zhen Chen, Stefanie K Pfister, Natalia Mast, Eylan Yutuc, Jiahui Chen, Yin-Long Li, Tuo Shao, Geoffrey I Warnock, Alyaa Dawoud, Theresa R Connors, Derek H Oakley, Huiyi Wei, Jinghao Wang, Zhihua Zheng, Hao Xu, April T Davenport, James B Daunais, Richard S Van, Yihan Shao, Yuqin Wang, Ming-Rong Zhang, Christian Loewe, Irina A Pikuleva, Allan L Levey, William J Griffiths, Steven H Liang
Assessment of cholesterol homeostasis in the living human brain. Science translational medicine 14 (665) (2022)
Jeffrey G McDonald, Christer S Ejsing, Dominik Kopczynski, Michal Holčapek, Junken Aoki, Makoto Arita, Masanori Arita, Erin S Baker, Justine Bertrand-Michel, John A Bowden, Britta Brügger, Shane R Ellis, Maria Fedorova, William J Griffiths, Xianlin Han, Jürgen Hartler, Nils Hoffmann, Jeremy P Koelmel, Harald C Köfeler, Todd W Mitchell, Valerie B O'Donnell, Daisuke Saigusa, Dominik Schwudke, Andrej Shevchenko, Candice Z Ulmer, Markus R Wenk, Michael Witting, Denise Wolrab, Yu Xia, Robert Ahrends, Gerhard Liebisch, Kim Ekroos
Introducing the Lipidomics Minimal Reporting Checklist. Nature metabolism 4 (9) (2022)
Harald C Köfeler, Thomas O Eichmann, Robert Ahrends, John A Bowden, Niklas Danne-Rasche, Edward A Dennis, Maria Fedorova, William J Griffiths, Xianlin Han, Jürgen Hartler, Michal Holčapek, Robert Jirásko, Jeremy P Koelmel, Christer S Ejsing, Gerhard Liebisch, Zhixu Ni, Valerie B O'Donnell, Oswald Quehenberger, Dominik Schwudke, Andrej Shevchenko, Michael J O Wakelam, Markus R Wenk, Denise Wolrab, Kim Ekroos
Quality control requirements for the correct annotation of lipidomics data. Nature communications 12 (1) (2021)
Thomas J R Ormsby, Sian E Owens, Anthony D Horlock, Daphne Davies, William J Griffiths, Yuqin Wang, James G Cronin, John James Bromfield, Iain Martin Sheldon
Oxysterols protect bovine endometrial cells against pore-forming toxins from pathogenic bacteria. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (10) (2021)
Roberto Angelini, Eylan Yutuc, Mark F Wyatt, Jillian Newton, Fowzi A Yusuf, Lauren Griffiths, Benjamin J Cooze, Dana El Assad, Gilles Frache, Wei Rao, Luke B Allen, Zeljka Korade, Thu T A Nguyen, Rathnayake A C Rathnayake, Stephanie M Cologna, Owain W Howell, Malcolm R Clench, Yuqin Wang, William J Griffiths
Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging. Analytical chemistry 93 (11) (2021)
Yuqin Wang, Eylan Yutuc, William J Griffiths
Cholesterol metabolism pathways - are the intermediates more important than the products? The FEBS journal 288 (12) (2021)
Ruochen Zang, James Brett Case, Eylan Yutuc, Xiucui Ma, Sheng Shen, María Florencia Gómez Castro, Zhuoming Liu, Qiru Zeng, Haiyan Zhao, Juhee Son, Paul W Rothlauf, Alex J B Kreutzberger, Gaopeng Hou, Hu Zhang, Sayantan Bose, Xin Wang, Michael D Vahey, Kartik Mani, William J Griffiths, Tomas Kirchhausen, Daved H Fremont, Haitao Guo, Abhinav Diwan, Yuqin Wang, Michael S Diamond, Sean P J Whelan, Siyuan Ding
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 117 (50) (2020)
Eylan Yutuc, Roberto Angelini, Mark Baumert, Natalia Mast, Irina A Pikuleva, Jillian Newton, Malcolm R Clench, David O F Skibinski, Owain W Howell, Yuqin Wang, William J Griffiths
Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Yuqin Wang, Eylan Yutuc, William J Griffiths
Neuro-oxysterols and neuro-sterols as ligands to nuclear receptors, GPCRs, ligand-gated ion channels and other protein receptors. British journal of pharmacology 178 (16) (2020)
Anna Meljon, Peter J Crick, Eylan Yutuc, Joyce L Yau, Jonathan R Seckl, Spyridon Theofilopoulos, Ernest Arenas, Yuqin Wang, William J Griffiths
Mining for Oxysterols in Cyp7b1-/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules 9 (4) (2019)
William J Griffiths, Yuqin Wang
Oxysterol research: a brief review. Biochemical Society transactions 47 (2) (2019)
Jonas Abdel-Khalik, Eylan Yutuc, Peter J Crick, Jan-Åke Gustafsson, Margaret Warner, Gustavo Roman, Kevin Talbot, Elizabeth Gray, William J Griffiths, Martin R Turner, Yuqin Wang
Defective cholesterol metabolism in amyotrophic lateral sclerosis. Journal of lipid research 58 (1) (2016)