William J Jusko

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 49

Top Topics

Cerebrospinal Fluid

Duchenne Muscular Dystrophy

Inflammatory Response

Top Venues

The Journal of pharmacology and experimental therapeutics

Drug metabolism and disposition: the biological fate of chemicals

Journal of clinical pharmacology

The AAPS journal

This page only lists publications with an associated author ORCID identifier.

Publications

Ofer Sadan, Yoo-Seong Jeong, Shany Cohen-Sadan, Eashani Sathialingam, Erin M Buckley, Prem A Kandiah, Jonathan A Grossberg, William Asbury, William J Jusko, Owen B Samuels
Cerebrospinal Fluid Pharmacokinetics of Nicardipine Following Intrathecal Administration in Subarachnoid Hemorrhage Patients. Journal of clinical pharmacology (2024)
Xiaonan Li, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, John McCall, Utkarsh J Dang, Eric P Hoffman, William J Jusko
Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. Journal of clinical pharmacology (2024)
Ruihong Yu, William J Jusko
Physiologically based pharmacokinetic modeling the reversible metabolism and tissue-specific partitioning of methylprednisolone and methylprednisone in rats . Drug metabolism and disposition: the biological fate of chemicals (2024)
Ruihong Yu, William J Jusko
Physiologically Based Pharmacokinetic Modeling: The Reversible Metabolism and Tissue-Specific Partitioning of Methylprednisolone and Methylprednisone in Rats. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Ruihong Yu, William J Jusko
Physiologically Based Pharmacokinetic Modeling: The Reversible Metabolism and Tissue-Specific Partitioning of Methylprednisolone and Methylprednisone in Rats. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Xiaonan Li, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, John McCall, Utkarsh J Dang, Eric P Hoffman, William J Jusko
Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. Journal of clinical pharmacology 64 (9) (2024)
Ruihong Yu, William J Jusko
Physiologically Based Pharmacokinetic Modeling: The Reversible Metabolism and Tissue-Specific Partitioning of Methylprednisolone and Methylprednisone in Rats. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Ofer Sadan, Yoo-Seong Jeong, Shany Cohen-Sadan, Eashani Sathialingam, Erin M Buckley, Prem A Kandiah, Jonathan A Grossberg, William Asbury, William J Jusko, Owen B Samuels
Reply to: Comment: Cerebrospinal Fluid Pharmacokinetics of Nicardipine Following Intrathecal Administration in Subarachnoid Hemorrhage Patients. Journal of clinical pharmacology (2024)
Xiaonan Li, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, John McCall, Utkarsh J Dang, Eric P Hoffman, William J Jusko
Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. Journal of clinical pharmacology 64 (9) (2024)
Ofer Sadan, Yoo-Seong Jeong, Shany Cohen-Sadan, Eashani Sathialingam, Erin M Buckley, Prem A Kandiah, Jonathan A Grossberg, William Asbury, William J Jusko, Owen B Samuels
Cerebrospinal Fluid Pharmacokinetics of Nicardipine Following Intrathecal Administration in Subarachnoid Hemorrhage Patients. Journal of clinical pharmacology (2024)
Xiaonan Li, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, John McCall, Utkarsh J Dang, Eric P Hoffman, William J Jusko
Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. Journal of clinical pharmacology 64 (9) (2024)
Xiaonan Li, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, John McCall, Utkarsh J Dang, Eric P Hoffman, William J Jusko
Assessing Pharmacogenomic loci Associated with the Pharmacokinetics of Vamorolone in Boys with Duchenne Muscular Dystrophy. Journal of clinical pharmacology 64 (9) (2024)
Ruihong Yu, William J Jusko
Physiologically Based Pharmacokinetic Modeling: The Reversible Metabolism and Tissue-Specific Partitioning of Methylprednisolone and Methylprednisone in Rats. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Ruihong Yu, William J Jusko
Physiologically Based Pharmacokinetic Modeling: The Reversible Metabolism and Tissue-Specific Partitioning of Methylprednisolone and Methylprednisone in Rats. Drug metabolism and disposition: the biological fate of chemicals 52 (7) (2024)
Yoo-Seong Jeong, William J Jusko
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models. The AAPS journal 25 (1) (2023)
Wojciech Krzyzanski, Mark A Milad, Alan H Jobe, William J Jusko
Minimal physiologically-based hybrid model of pharmacokinetics in pregnant women: Application to antenatal corticosteroids. CPT: pharmacometrics & systems pharmacology (2023)
Xiaonan Li, William J Jusko
Exploring the Pharmacokinetic Mysteries of the Liver: Application of Series Compartment Models of Hepatic Elimination . Drug metabolism and disposition: the biological fate of chemicals (2023)
Yoo-Seong Jeong, William J Jusko
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models. The AAPS journal 25 (1) (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome . The Journal of pharmacology and experimental therapeutics (2023)
Xiaonan Li, William J Jusko
Utility of Minimal Physiologically-Based Pharmacokinetic (mPBPK) Models for Assessing Fractional Distribution, Oral Absorption and Series-Compartment Models of Hepatic Clearance . Drug metabolism and disposition: the biological fate of chemicals (2023)
Yoo-Seong Jeong, William J Jusko
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models. The AAPS journal 25 (1) (2023)
Xiaonan Li, William J Jusko
Exploring the Pharmacokinetic Mysteries of the Liver: Application of Series Compartment Models of Hepatic Elimination . Drug metabolism and disposition: the biological fate of chemicals (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome . The Journal of pharmacology and experimental therapeutics (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
Yoo-Seong Jeong, William J Jusko
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models. The AAPS journal 25 (1) (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome. The Journal of pharmacology and experimental therapeutics 384 (3) (2023)
Yoo-Seong Jeong, William J Jusko
Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration-Time Relationships in Minimal Physiologically Based Pharmacokinetic Models. The AAPS journal 25 (1) (2023)
Artur Świerczek, William J Jusko
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome . The Journal of pharmacology and experimental therapeutics (2023)
Xiaonan Li, William J Jusko
Assessing Liver-to-Plasma Partition Coefficients and In Silico Calculation Methods: When Does the Hepatic Model Matter in PBPK? Drug metabolism and disposition: the biological fate of chemicals (2022)
Yoo-Seong Jeong, William J Jusko
Determinants of Biological Half-Lives and Terminal Slopes in Physiologically Based Pharmacokinetic Systems: Assessment of Limiting Conditions. The AAPS journal 24 (5) (2022)
Yoo-Seong Jeong, William J Jusko
Consideration of Fractional Distribution Parameter f d in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods. Pharmaceutical research 39 (3) (2022)
Wojciech Krzyzanski, Mark A Milad, Alan H Jobe, Thomas Peppard, Robert R Bies, William J Jusko
Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women. Journal of pharmacokinetics and pharmacodynamics 48 (2) (2021)
Wojciech Krzyzanski, Mark A Milad, Alan H Jobe, Thomas Peppard, Robert R Bies, William J Jusko
Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of pharmacokinetics and pharmacodynamics 48 (3) (2021)
Dawei Song, William J Jusko
Across-species meta-analysis of dexamethasone pharmacokinetics utilizing allometric and scaling modeling approaches. Biopharmaceutics & drug disposition 42 (5) (2021)
William J Jusko, Xiaonan Li
Assessment of the Kochak-Benet Equation for Hepatic Clearance for the Parallel-Tube Model: Relevance of Classic Clearance Concepts in PK and PBPK. The AAPS journal 24 (1) (2021)
Xiaonan Li, Laurie S Conklin, John van den Anker, Eric P Hoffman, Paula R Clemens, William J Jusko
Exposure-Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy. Journal of clinical pharmacology 60 (10) (2020)
Ruihong Yu, Xiaonan Li, Debra C DuBois, Richard R Almon, Yongxiao Cao, William J Jusko
Interactions of Tofacitinib and Dexamethasone on Lymphocyte Proliferation. Pharmaceutical research 37 (6) (2020)
Vivaswath S Ayyar, Debra C DuBois, Richard R Almon, William J Jusko
Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part III: Estrous Cycle and Estrogen Receptor-Dependent Antagonism of Glucocorticoid-Induced Leucine Zipper (GILZ) Enhancement by Corticosteroids. The Journal of pharmacology and experimental therapeutics 370 (2) (2019)
Vivaswath S Ayyar, Dawei Song, Debra C DuBois, Richard R Almon, William J Jusko
Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat. The Journal of pharmacology and experimental therapeutics 370 (2) (2019)
Vivaswath S Ayyar, Debra C DuBois, Toshimichi Nakamura, Richard R Almon, William J Jusko
Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression. The Journal of pharmacology and experimental therapeutics 370 (2) (2019)
Vivaswath S Ayyar, Wojciech Krzyzanski, William J Jusko
Indirect pharmacodynamic models for responses with circadian removal. Journal of pharmacokinetics and pharmacodynamics 46 (1) (2019)
Panteleimon D Mavroudis, John van den Anker, Laurie S Conklin, Jesse M Damsker, Eric P Hoffman, Kanneboyina Nagaraju, Paula R Clemens, William J Jusko
Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy. Journal of clinical pharmacology 59 (7) (2019)
Ruihong Yu, Dawei Song, Debra C DuBois, Richard R Almon, William J Jusko
Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats. The AAPS journal 21 (5) (2019)
Vivaswath S Ayyar, Siddharth Sukumaran, Debra C DuBois, Richard R Almon, William J Jusko
Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver. The Journal of pharmacology and experimental therapeutics 367 (1) (2018)
Dawei Song, Debra C DuBois, Richard R Almon, William J Jusko
Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats. Pharmaceutical research 35 (11) (2018)
Xu Zhu, Sheryl Trueman, Robert M Straubinger, William J Jusko
Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts. Journal of pharmacokinetics and pharmacodynamics 45 (5) (2018)
Vivaswath S Ayyar, Siddharth Sukumaran, Debra C DuBois, Richard R Almon, Jun Qu, William J Jusko
Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver. Journal of pharmacokinetics and pharmacodynamics 45 (4) (2018)