Xinghua Lu

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 44

Top Topics

Advanced Non Small Cell Lung Cancer

Tyrosine Kinase

Top Venues

Science advances

PLoS computational biology

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Future oncology (London, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing H Wang, Edward Chu, Jing Hu
FAK loss reduces BRAF V600E -induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. eLife 13 (2024)
Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing H Wang, Edward Chu, Jing Hu
FAK loss reduces BRAF V600E -induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. eLife 13 (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (13) (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) 20 (17) (2024)
Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing H Wang, Edward Chu, Jing Hu
FAK loss reduces BRAF V600E -induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. eLife 13 (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (13) (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing H Wang, Edward Chu, Jing Hu
FAK loss reduces BRAF V600E -induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. eLife 13 (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) 20 (17) (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) 20 (17) (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) (2024)
Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing H Wang, Edward Chu, Jing Hu
FAK loss reduces BRAF V600E -induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. eLife 13 (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Lujia Chen, Ying Wang, Chunhui Cai, Ying Ding, Rim S Kim, Corey Lipchik, Patrick G Gavin, Greg Yothers, Carmen J Allegra, Nicholas J Petrelli, Jennifer Marie Suga, Judith O Hopkins, Naoyuki G Saito, Terry Evans, Srinivas Jujjavarapu, Norman Wolmark, Peter C Lucas, Soonmyung Paik, Min Sun, Katherine L Pogue-Geile, Xinghua Lu
Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (13) (2024)
Han Zhang, Xinghua Lu, Binfeng Lu, Giuseppe Gullo, Lujia Chen
Measuring the composition of the tumor microenvironment with transcriptome analysis: past, present and future. Future oncology (London, England) (2024)
Runzi Sun, Hongyu Zhao, David Shihong Gao, Andrew Ni, Haochen Li, Lujia Chen, Xinghua Lu, Kong Chen, Binfeng Lu
Amphiregulin couples IL1RL1 + regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity. Science advances 9 (34) (2023)
Shuangxia Ren, Gregory F Cooper, Lujia Chen, Xinghua Lu
An interpretable deep learning framework for genome-informed precision oncology. bioRxiv : the preprint server for biology (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Chenxi Gao, Huaibin Ge, Shih-Fan Kuan, Chunhui Cai, Xinghua Lu, Farzad Esni, Robert E Schoen, Jing Hong Wang, Edward Chu, Jing Hu
FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. Research square (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gradishar, Kevin Kalinsky, Yongmei Yin, Bin Zhang, Yong Wan
Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity. Science advances 9 (1) (2023)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Yifeng Tao, Xiaojun Ma, Drake Palmer, Russell Schwartz, Xinghua Lu, Hatice Ulku Osmanbeyoglu
Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers. Nucleic acids research 50 (19) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Manqi Cai, Molin Yue, Tianmeng Chen, Jinling Liu, Erick Forno, Xinghua Lu, Timothy Billiar, Juan C Celedón, Chris McKennan, Wei Chen, Jiebiao Wang
Robust and accurate estimation of cellular fraction from tissue omics data via ensemble deconvolution. Bioinformatics (Oxford, England) 38 (11) (2022)
Xueer Chen, Lujia Chen, Cornelius H L Kürten, Fattaneh Jabbari, Lazar Vujanovic, Ying Ding, Binfeng Lu, Kevin Lu, Aditi Kulkarni, Tracy Tabib, Robert Lafyatis, Gregory F Cooper, Robert Ferris, Xinghua Lu
An individualized causal framework for learning intercellular communication networks that define microenvironments of individual tumors. PLoS computational biology 18 (12) (2022)
Brian J Leibowitz, Guangyi Zhao, Liang Wei, Hang Ruan, Michael W Epperly, Lujia Chen, Xinghua Lu, Joel S Greenberger, Lin Zhang, Jian Yu
Interferon b drives intestinal regeneration after radiation. Science advances 7 (41) (2021)
Cornelius H L Kürten, Aditi Kulkarni, Anthony R Cillo, Patricia M Santos, Anna K Roble, Sayali Onkar, Carly Reeder, Stephan Lang, Xueer Chen, Umamaheswar Duvvuri, Seungwon Kim, Angen Liu, Tracy Tabib, Robert Lafyatis, Jian Feng, Shou-Jiang Gao, Tullia C Bruno, Dario A A Vignali, Xinghua Lu, Riyue Bao, Lazar Vujanovic, Robert L Ferris
Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing. Nature communications 12 (1) (2021)
Yifan Xue, Michael Q Ding, Xinghua Lu
Learning to encode cellular responses to systematic perturbations with deep generative models. NPJ systems biology and applications 6 (1) (2020)
Hang Ruan, Xiangyun Li, Xiang Xu, Brian J Leibowitz, Jingshan Tong, Lujia Chen, Luoquan Ao, Wei Xing, Jianhua Luo, Yanping Yu, Robert E Schoen, Nahum Sonenberg, Xinghua Lu, Lin Zhang, Jian Yu
eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis. eLife 9 (2020)
Chunhui Cai, Gregory F Cooper, Kevin N Lu, Xiaojun Ma, Shuping Xu, Zhenlong Zhao, Xueer Chen, Yifan Xue, Adrian V Lee, Nathan Clark, Vicky Chen, Songjian Lu, Lujia Chen, Liyue Yu, Harry S Hochheiser, Xia Jiang, Q Jane Wang, Xinghua Lu
Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference. PLoS computational biology 15 (7) (2019)
Rajendra P Pangeni, Zhou Zhang, Angel A Alvarez, Xuechao Wan, Namratha Sastry, Songjian Lu, Taiping Shi, Tianzhi Huang, Charles X Lei, C David James, John A Kessler, Cameron W Brennan, Ichiro Nakano, Xinghua Lu, Bo Hu, Wei Zhang, Shi-Yuan Cheng
Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma. Epigenetics 13 (4) (2018)
Tianzhi Huang, Angel A Alvarez, Rajendra P Pangeni, Craig M Horbinski, Songjian Lu, Sung-Hak Kim, C David James, Jeffery J Raizer, John A Kessler, Cameron W Brenann, Erik P Sulman, Gaetano Finocchiaro, Ming Tan, Ryo Nishikawa, Xinghua Lu, Ichiro Nakano, Bo Hu, Shi-Yuan Cheng
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nature communications 7 (2016)