Yilun Sun

ORCID

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 13

Top Venues

Nature communications

Science advances

Molecular cancer therapeutics

Molecular cancer research : MCR

National Institutes of Health

University of Illinois at Chicago (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institutes of Health Jan 08 2018

United States

Postdoctoral fellow

Education History

University of Illinois at Chicago Aug 15 2012 - Dec 17 2017

United States

PHD :: Biopharmaceutical Sciences

Publications

Liton Kumar Saha, Sourav Saha, Xi Yang, Shar-Yin Naomi Huang, Yilun Sun, Ukhyun Jo, Yves Pommier
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes. Nature communications 14 (1) (2023)
Yilun Sun, Jiji Chen, Yves Pommier
Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level. Nucleic acids research (2023)
Huimin Zhang, Yun Xiong, Yilun Sun, Jeong-Min Park, Dan Su, Xu Feng, Sarah Keast, Mengfan Tang, Min Huang, Chao Wang, Mrinal Srivastava, Chang Yang, Dandan Zhu, Zhen Chen, Siting Li, Ling Yin, Yves Pommier, Junjie Chen
RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons. Science advances 9 (49) (2023)
Sourav Saha, Shar-Yin Naomi Huang, Xi Yang, Liton Kumar Saha, Yilun Sun, Prashant Khandagale, Lisa M Miller Jenkins, Yves Pommier
The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes. Nature communications 14 (1) (2023)
Yilun Sun, Simone A Baechler, Xiaohu Zhang, Suresh Kumar, Valentina M Factor, Yasuhiro Arakawa, Cindy H Chau, Kanako Okamoto, Anup Parikh, Robert L Walker, Yijun P Su, Jiji Chen, Tabitha Ting, Shar-Yin N Huang, Erin Beck, Zina Itkin, Crystal McKnight, Changqing Xie, Nitin Roper, Deepak Nijhawan, William Douglas Figg, Paul S Meltzer, James C Yang, Craig J Thomas, Yves Pommier
Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex. Nature communications 14 (1) (2023)
Yilun Sun, Yang Zhang, Christopher W Schultz, Yves Pommier, Anish Thomas
CDK7 Inhibition Synergizes with Topoisomerase I Inhibition in Small Cell Lung Cancer Cells by Inducing Ubiquitin-Mediated Proteolysis of RNA Polymerase II. Molecular cancer therapeutics 21 (9) (2022)
Ukhyun Jo, Yasuhisa Murai, Keli K Agama, Yilun Sun, Liton Kumar Saha, Xi Yang, Yasuhiro Arakawa, Sophia Gayle, Kelli Jones, Vishwas Paralkar, Ranjini K Sundaram, Jinny Van Doorn, Juan C Vasquez, Ranjit S Bindra, Woo Suk Choi, Yves Pommier
TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor. Molecular cancer therapeutics 21 (7) (2022)
Dragomir B Krastev, Shudong Li, Yilun Sun, Andrew J Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M Badder, Eleanor G Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T Talele, Jiri Bartek, Jyoti Sharma Choudhary, Yves Pommier, Stephen J Pettitt, Andrew N J Tutt, Kristijan Ramadan, Christopher J Lord
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin. Nature cell biology 24 (1) (2022)
Yicong Wu, Xiaofei Han, Yijun Su, Melissa Glidewell, Jonathan S Daniels, Jiamin Liu, Titas Sengupta, Ivan Rey-Suarez, Robert Fischer, Akshay Patel, Christian Combs, Junhui Sun, Xufeng Wu, Ryan Christensen, Corey Smith, Lingyu Bao, Yilun Sun, Leighton H Duncan, Jiji Chen, Yves Pommier, Yun-Bo Shi, Elizabeth Murphy, Sougata Roy, Arpita Upadhyaya, Daniel Alfonso Colón-Ramos, Patrick La Riviere, Hari Shroff
Multiview confocal super-resolution microscopy. Nature 600 (7888) (2021)
Yilun Sun, Jiji Chen, Shar-Yin N Huang, Yijun P Su, Wenjie Wang, Keli Agama, Sourav Saha, Lisa M Jenkins, John M Pascal, Yves Pommier
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation. Nature communications 12 (1) (2021)
Liliya Tyutyunyk-Massey, Yilun Sun, Nga Dao, Hannah Ngo, Mallika Dammalapati, Ashish Vaidyanathan, Manjulata Singh, Syed Haqqani, Joshua Haueis, Ryan Finnegan, Xiaoyan Deng, Steve E Kirberger, Paula D Bos, Dipankar Bandyopadhyay, William C K Pomerantz, Yves Pommier, David A Gewirtz, Joseph W Landry
Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor. Molecular cancer research : MCR 19 (8) (2021)
Yilun Sun, Lisa M Miller Jenkins, Yijun P Su, Karin C Nitiss, John L Nitiss, Yves Pommier
A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation. Science advances 6 (46) (2020)
Nicole Stantial, Anna Rogojina, Matthew Gilbertson, Yilun Sun, Hannah N Miles, Samantha Shaltz, James M Berger, Karin C Nitiss, Sue Jinks-Robertson, John L Nitiss
Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast. Proceedings of the National Academy of Sciences of the United States of America 117 (43) (2020)

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Publication Activity (10 Years)

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Yilun Sun