Yu-Guo Zheng (Yuguo Zheng)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 62

Top Topics

Escherichia Coli

St Segment Elevation Myocardial Infarction

Magnetic Nanoparticles

Top Venues

Biotechnology and bioengineering

ACS synthetic biology

Journal of agricultural and food chemistry

Biotechnology progress

This page only lists publications with an associated author ORCID identifier.

Publications

Xue Cai, Xue Shi, Jia-Ying Wang, Cheng-Hao Hu, Ji-Dong Shen, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng
Enhancing the Thermal Stability and Enzyme Activity of Ketopantoate Hydroxymethyltransferase through Interface Modification Engineering. Journal of agricultural and food chemistry 72 (23) (2024)
Feng Cheng, Ke-Xin Li, Shan-Shan Wu, Hai-Yun Liu, Huan Li, Qi Shen, Ya-Ping Xue, Yu-Guo Zheng
Biosynthesis of Nicotinamide Mononucleotide: Synthesis Method, Enzyme, and Biocatalytic System. Journal of agricultural and food chemistry (2024)
Yuanyuan Chen, Lianggang Huang, Tao Yu, Yuan Yao, Mingming Zhao, Aiping Pang, Junping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng
Balancing the AspC and AspA Pathways of Escherichia coli by Systematic Metabolic Engineering Strategy for High-Efficient l-Homoserine Production. ACS synthetic biology 13 (8) (2024)
Feng Cheng, Ke-Xin Li, Shan-Shan Wu, Hai-Yun Liu, Huan Li, Qi Shen, Ya-Ping Xue, Yu-Guo Zheng
Biosynthesis of Nicotinamide Mononucleotide: Synthesis Method, Enzyme, and Biocatalytic System. Journal of agricultural and food chemistry 72 (7) (2024)
Shen-Yuan Xu, Rong-Liang Chu, Hua-Tao Liu, Chun-Yue Weng, Ya-Jun Wang, Yu-Guo Zheng
Computer-directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor. Biotechnology and bioengineering 121 (5) (2024)
Feng Cheng, Ke-Xin Li, Shan-Shan Wu, Hai-Yun Liu, Huan Li, Qi Shen, Ya-Ping Xue, Yu-Guo Zheng
Biosynthesis of Nicotinamide Mononucleotide: Synthesis Method, Enzyme, and Biocatalytic System. Journal of agricultural and food chemistry 72 (7) (2024)
Yu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng
Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield. Organic & biomolecular chemistry 22 (15) (2024)
Yu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng
Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield. Organic & biomolecular chemistry 22 (15) (2024)
Yuanyuan Chen, Lianggang Huang, Tao Yu, Yuan Yao, Mingming Zhao, Aiping Pang, Junping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng
Balancing the AspC and AspA Pathways of Escherichia coli by Systematic Metabolic Engineering Strategy for High-Efficient l-Homoserine Production. ACS synthetic biology (2024)
Yu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng
Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield. Organic & biomolecular chemistry (2024)
Yu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng
Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield. Organic & biomolecular chemistry 22 (15) (2024)
Feng Peng, Qi Shen, Lu-Ping Zou, Feng Cheng, Ya-Ping Xue, Yu-Guo Zheng
Design of NAMPTs with Superior Activity by Dual-Channel Protein Engineering Strategy. Journal of agricultural and food chemistry (2024)
Xue Cai, Xue Shi, Jia-Ying Wang, Cheng-Hao Hu, Ji-Dong Shen, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng
Enhancing the Thermal Stability and Enzyme Activity of Ketopantoate Hydroxymethyltransferase through Interface Modification Engineering. Journal of agricultural and food chemistry (2024)
Feng Cheng, Ke-Xiang Sun, Xiao-Xiao Gong, Wei Peng, Hua-Yue Zhang, Xi-Hang Liang, Ya-Ping Xue, Yu-Guo Zheng
Development of growth selection system and pocket engineering of d-amino acid oxidase to enhance selective deamination activity toward d-phosphinothricin. Biotechnology and bioengineering 121 (9) (2024)
Shen-Yuan Xu, Rong-Liang Chu, Hua-Tao Liu, Chun-Yue Weng, Ya-Jun Wang, Yu-Guo Zheng
Computer-directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor. Biotechnology and bioengineering (2024)
Hai-Yan Zhou, Wen-Qing Ding, Xi Zhang, Hong-Yu Zhang, Zhong-Ce Hu, Zhi-Qiang Liu, Yu-Guo Zheng
Fine and combinatorial regulation of key metabolic pathway for enhanced β-alanine biosynthesis with non-inducible Escherichia coli. Biotechnology and bioengineering (2024)
Yuanyuan Chen, Lianggang Huang, Tao Yu, Yuan Yao, Mingming Zhao, Aiping Pang, Junping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng
Balancing the AspC and AspA Pathways of Escherichia coli by Systematic Metabolic Engineering Strategy for High-Efficient l-Homoserine Production. ACS synthetic biology 13 (8) (2024)
Shen-Yuan Xu, Rong-Liang Chu, Hua-Tao Liu, Chun-Yue Weng, Ya-Jun Wang, Yu-Guo Zheng
Computer-directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor. Biotechnology and bioengineering 121 (5) (2024)
Feng Cheng, Ke-Xiang Sun, Xiao-Xiao Gong, Wei Peng, Hua-Yue Zhang, Xi-Hang Liang, Ya-Ping Xue, Yu-Guo Zheng
Development of growth selection system and pocket engineering of d-amino acid oxidase to enhance selective deamination activity toward d-phosphinothricin. Biotechnology and bioengineering (2024)
Liuyu Wang, Heng Tang, Hongli Zhu, Ya-Ping Xue, Yu-Guo Zheng
Enhancement of the substrate specificity of D-amino acid oxidase based on tunnel-pocket engineering. Biotechnology and bioengineering (2023)
Bo Zhang, Hui Yang, Zidan Wu, Jiayuan Pan, Shirong Li, Lifeng Chen, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zheng
Spatiotemporal Gene Expression by a Genetic Circuit for Chemical Production in Escherichia coli . ACS synthetic biology (2023)
Kun Niu, Qiang Fu, Zi-Long Mei, Li-Rong Ge, An-Qi Guan, Zhi-Qiang Liu, Yu-Guo Zheng
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli . ACS synthetic biology 12 (2) (2023)
Liu-Yu Wang, Heng Tang, Jin-Qiao Zhao, Meng-Nan Wang, Ya-Ping Xue, Yu-Guo Zheng
Correlation Analysis of Key Residue Sites between Computational-Aided Design Thermostability d-Amino Acid Oxidase and Ancestral Enzymes. Journal of agricultural and food chemistry (2023)
Bo Zhang, Hui Yang, Zidan Wu, Jiayuan Pan, Shirong Li, Lifeng Chen, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zheng
Spatiotemporal Gene Expression by a Genetic Circuit for Chemical Production in Escherichia coli . ACS synthetic biology 12 (3) (2023)
Kun Niu, Qiang Fu, Zi-Long Mei, Li-Rong Ge, An-Qi Guan, Zhi-Qiang Liu, Yu-Guo Zheng
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli . ACS synthetic biology (2023)
Bo Zhang, Hui Yang, Zidan Wu, Jiayuan Pan, Shirong Li, Lifeng Chen, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zheng
Spatiotemporal Gene Expression by a Genetic Circuit for Chemical Production in Escherichia coli . ACS synthetic biology 12 (3) (2023)
Hua-Tao Liu, Chun-Yue Weng, Lei Zhou, Hao-Bo Xu, Zhen-Yu Liao, Han-Yue Hong, Yuan-Fan Ye, Shu-Fang Li, Ya-Jun Wang, Yu-Guo Zheng
Coevolving stability and activity of LsCR by a single point mutation and constructing neat substrate bioreaction system. Biotechnology and bioengineering (2023)
Hua-Tao Liu, Chun-Yue Weng, Lei Zhou, Hao-Bo Xu, Zhen-Yu Liao, Han-Yue Hong, Yuan-Fan Ye, Shu-Fang Li, Ya-Jun Wang, Yu-Guo Zheng
Co-evolving Stability and Activity of LsCR by A Single Point Mutation and Constructing Neat Substrate Bioreaction System. Biotechnology and bioengineering (2023)
Feng Cheng, Lan Wei, Cheng-Jiao Wang, Xi-Hang Liang, Yue-Qiang Xu, Ya-Ping Xue, Yu-Guo Zheng
Switching the Cofactor Preference of Formate Dehydrogenase to Develop an NADPH-Dependent Biocatalytic System for Synthesizing Chiral Amino Acids. Journal of agricultural and food chemistry (2023)
Kun Niu, Qiang Fu, Zi-Long Mei, Li-Rong Ge, An-Qi Guan, Zhi-Qiang Liu, Yu-Guo Zheng
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli . ACS synthetic biology 12 (2) (2023)
Kun Niu, Qiang Fu, Zi-Long Mei, Li-Rong Ge, An-Qi Guan, Zhi-Qiang Liu, Yu-Guo Zheng
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli . ACS synthetic biology 12 (2) (2023)
Shen-Yuan Xu, Lei Zhou, Ying Xu, Han-Yue Hong, Chen Dai, Ya-Jun Wang, Yu-Guo Zheng
Recent advances in structure-based enzyme engineering for functional reconstruction. Biotechnology and bioengineering (2023)
Kun Niu, Qiang Fu, Zi-Long Mei, Li-Rong Ge, An-Qi Guan, Zhi-Qiang Liu, Yu-Guo Zheng
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli . ACS synthetic biology 12 (2) (2023)
Hui Yang, Bo Zhang, Zi-Dan Wu, Li-Feng Chen, Jia-Yuan Pan, Xiao-Ling Xiu, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zheng
Combinatorial Metabolic Engineering of Escherichia coli for Enhanced L-Cysteine Production: Insights into Crucial Regulatory Modes and Optimization of Carbon-Sulfur Metabolism and Cofactor Availability. Journal of agricultural and food chemistry (2023)
Chen Dai, Hai-Xing Cao, Jia-Xin Tian, Yan-Chi Gao, Hua-Tao Liu, Shen-Yuan Xu, Ya-Jun Wang, Yu-Guo Zheng
Structural-guided design to improve the catalytic performance of aldo-keto reductase KdAKR. Biotechnology and bioengineering (2023)
Han-Lin Liu, Jia-Min Wu, Xin-Tong Deng, Lan Yu, Pu-Hong Yi, Zhi-Qiang Liu, Ya-Ping Xue, Li-Qun Jin, Yu-Guo Zheng
Development of an aminotransferase-driven biocatalytic cascade for deracemization of d,l-phosphinothricin. Biotechnology and bioengineering (2023)
Xia-Feng Lu, Hong-Juan Diao, Zhe-Ming Wu, Zi-Long Zhang, Ren-Chao Zheng, Yu-Guo Zheng
Engineering of reaction specificity, enantioselectivity, and catalytic activity of nitrilase for highly efficient synthesis of pregabalin precursor. Biotechnology and bioengineering 119 (9) (2022)
Xiao-Ling Tang, Ke-Xin Xu, Yu-Heng Geng, Wen-Hao Wang, Hong-Juan Diao, Ren-Chao Zheng, Yu-Guo Zheng
Regulating substrate preference of phosphatase by reshaping the "cap domain" for multi-enzymatic biosynthesis of high-purity monosaccharides. Biotechnology and bioengineering 119 (12) (2022)
Xiao-Ling Tang, Yu-Yi Li, Yue Mao, Ren-Chao Zheng, Yu-Guo Zheng
Improvement of multicatalytic properties of nitrilase from Paraburkholderia graminis for efficient biosynthesis of 2-chloronicotinic acid. Biotechnology and bioengineering 119 (12) (2022)
Bo Li, Bo Zhang, Pei Wang, Xue Cai, Yuan-Yuan Chen, Yu-Feng Yang, Zhi-Qiang Liu, Yu-Guo Zheng
Rerouting Fluxes of the Central Carbon Metabolism and Relieving Mechanism-Based Inactivation of l-Aspartate-α-decarboxylase for Fermentative Production of β-Alanine in Escherichia coli . ACS synthetic biology 11 (5) (2022)
Feng Cheng, Ming-You Li, Dian-Ju Wei, Xiao-Jian Zhang, Dong-Xu Jia, Zhi-Qiang Liu, Yu-Guo Zheng
Enabling biocatalysis in high-concentration organic cosolvent by enzyme gate engineering. Biotechnology and bioengineering 119 (3) (2021)
Xiao-Jian Zhang, Feng-Yu Qi, Jia-Mei Qi, Fei Yang, Jiang-Wei Shen, Xue Cai, Zhi-Qiang Liu, Yu-Guo Zheng
Efficient enzymatic synthesis of L-ascorbyl palmitate using Candida antarctica lipase B-embedded metal-organic framework. Biotechnology progress (2021)
Feng Cheng, Qiu-Yao Zhai, Xiao-Fan Gao, Hua-Tao Liu, Shuai Qiu, Ya-Jun Wang, Yu-Guo Zheng
Tuning enzymatic properties by protein engineering toward catalytic tetrad of carbonyl reductase. Biotechnology and bioengineering 118 (12) (2021)
Kai Huang, Bo Zhang, Yu Chen, Zhe-Ming Wu, Zhi-Qiang Liu, Yu-Guo Zheng
Analysis of the effects of different nitrogen sources and calcium on the production of amphotericin by Streptomyces nodosus based on comparative transcriptome. Biotechnology and applied biochemistry (2021)
Shu-Fang Li, Jian-Yong Xie, Shuai Qiu, Shen-Yuan Xu, Feng Cheng, Ya-Jun Wang, Yu-Guo Zheng
Semirational engineering of an aldo-keto reductase KmAKR for overcoming trade-offs between catalytic activity and thermostability. Biotechnology and bioengineering 118 (11) (2021)
Xiao-Jian Zhang, Hai-Wei Li, Wang Bin, Bao-Juan Dou, De-Shui Chen, Xin-Ping Cheng, Mian Li, Hong-Yan Wang, Kai-Qian Chen, Li-Qun Jin, Zhi-Qiang Liu, Yu-Guo Zheng
Efficient Synthesis of Sugar Alcohols under Mild Conditions Using a Novel Sugar-Selective Hydrogenation Catalyst Based on Ruthenium Valence Regulation. Journal of agricultural and food chemistry 68 (44) (2020)
Xiao-Jian Zhang, Rong Zhou, Di Wu, Ya-Qun Tang, Meng-Ying Wang, Zhi-Qiang Liu, Yu-Guo Zheng
Efficient production of an ezetimibe intermediate using carbonyl reductase coupled with glucose dehydrogenase. Biotechnology progress 37 (1) (2020)
Shu-Ping Zou, Zhi-Jian Wang, Kuo Zhao, Bo Zhang, Kun Niu, Zhi-Qiang Liu, Yu-Guo Zheng
High-level production of d-pantothenic acid from glucose by fed-batch cultivation of Escherichia coli. Biotechnology and applied biochemistry (2020)
Chao-Ping Lin, Yue Mao, Ren-Chao Zheng, Yu-Guo Zheng
Highly Efficient Chemoenzymatic Synthesis of l-Phosphinothricin from N-Phenylacetyl-d,l-phosphinothricin by a Robust Immobilized Amidase. Journal of agricultural and food chemistry 68 (49) (2020)
Xiao-Jian Zhang, Ling Zheng, Di Wu, Rong Zhou, Zhi-Qiang Liu, Yu-Guo Zheng
Production of tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate using carbonyl reductase coupled with glucose dehydrogenase with high space-time yield. Biotechnology progress 36 (1) (2019)
Hai-Feng Hu, Hai-Yan Zhou, Gao-Ping Cheng, Ya-Ping Xue, Yuan-Shan Wang, Yu-Guo Zheng
Improvement of R-2-(4-hydroxyphenoxy) propionic acid biosynthesis of Beauveria bassiana by combined mutagenesis. Biotechnology and applied biochemistry 67 (3) (2019)
Shu-Ping Zou, Yan Xiong, Kun Niu, Zhong-Ce Hu, Yu-Guo Zheng
Integrated strategy of temperature shift and mannitol feeding for enhanced production of echinocandin B by Aspergillus nidulans CCTCC M2012300. 3 Biotech 9 (4) (2019)
Qin Zhang, Xia-Feng Lu, Yan Zhang, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng
Development of a robust nitrilase by fragment swapping and semi-rational design for efficient biosynthesis of pregabalin precursor. Biotechnology and bioengineering 117 (2) (2019)
Zhong-Ce Hu, Jia-Li Bu, Ru-Yi Wang, Xia Ke, Yu-Guo Zheng
Enhanced Production of 6-(N-Hydroxyethyl)-Amino-6-Deoxy-α-L-Sorbofuranose by Immobilized Gluconobacter oxydanson Corn Stover with a pH Control Strategy in a Bubble Column Bioreactor. Applied biochemistry and biotechnology 188 (2) (2018)
Jian-Feng Huang, Zhen-Yang Shen, Qiao-Li Mao, Xiao-Ming Zhang, Bo Zhang, Jia-Shu Wu, Zhi-Qiang Liu, Yu-Guo Zheng
Systematic Analysis of Bottlenecks in a Multibranched and Multilevel Regulated Pathway: The Molecular Fundamentals of l-Methionine Biosynthesis in Escherichia coli. ACS synthetic biology 7 (11) (2018)
Shu-Ping Zou, Kai Gu, Yu-Guo Zheng
Covalent immobilization of halohydrin dehalogenase for efficient synthesis of epichlorohydrin in an integrated bioreactor. Biotechnology progress 34 (3) (2018)
Ya-Ping Xue, Chuang Wang, Di-Chen Wang, Zhi-Qiang Liu, Yu-Guo Zheng
Highly Efficient Deracemization of Racemic 2-Hydroxy Acids in a Three-Enzyme Co-Expression System Using a Novel Ketoacid Reductase. Applied biochemistry and biotechnology 186 (3) (2018)
Xu Ding, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng
Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized Talaromyces thermophilus Lipase. BioMed research international 2018 (2018)
Ya-Jun Wang, Wei Shen, Xi Luo, Zhi-Qiang Liu, Yu-Guo Zheng
Enhanced diastereoselective synthesis of t-Butyl 6-cyano-(3R,5R)-dihydroxyhexanoate by using aldo-keto reductase and glucose dehydrogenase co-producing engineered Escherichia coli. Biotechnology progress 33 (5) (2017)
Zhi-Qiang Liu, Bo Zhang, Shan Lin, Peter James Baker, Mao-Sheng Chen, Ya-Ping Xue, Hui Wu, Feng Xu, Shui-Jin Yuan, Yi Teng, Ling-Fang Wu, Yu-Guo Zheng
Enhancement of Nucleoside Production in Hirsutella sinensis Based on Biosynthetic Pathway Analysis. BioMed research international 2017 (2017)
Zhi-Qiang Liu, Lin Wu, Xiao-Jian Zhang, Ya-Ping Xue, Yu-Guo Zheng
Directed Evolution of Carbonyl Reductase from Rhodosporidium toruloides and Its Application in Stereoselective Synthesis of tert-Butyl (3R,5S)-6-Chloro-3,5-dihydroxyhexanoate. Journal of agricultural and food chemistry 65 (18) (2017)
Hongli Fang, Yandong Dou, Jingyan Ge, Mohit Chhabra, Hongyan Sun, Pengfei Zhang, Yu-Guo Zheng, Qing Zhu
Regioselective and Direct Azidation of Anilines via Cu(II)-Catalyzed C-H Functionalization in Water. The Journal of organic chemistry 82 (20) (2017)