Yuan Chen

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 15

Top Topics

Liquid Chromatography Tandem Mass Spectrometry

Top Venues

CPT: pharmacometrics & systems pharmacology

Clinical pharmacology and therapeutics

Biopharmaceutics & drug disposition

Biomedical chromatography : BMC

This page only lists publications with an associated author ORCID identifier.

Publications

Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Gerald R Galluppi, Malidi Ahamadi, Souvik Bhattacharya, Nageshwar Budha, Ferdous Gheyas, Chi-Chung Li, Yuan Chen, Anne-Gaëlle Dosne, Niels Rode Kristensen, Mindy Magee, Mahesh N Samtani, Vikram Sinha, Kunal S Taskar, Vijay V Upreti, Jianning Yang, Jack Cook
Considerations for Industry-Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program. Clinical pharmacology and therapeutics 116 (2) (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Gerald R Galluppi, Malidi Ahamadi, Souvik Bhattacharya, Nageshwar Budha, Ferdous Gheyas, Chi-Chung Li, Yuan Chen, Anne-Gaëlle Dosne, Niels Rode Kristensen, Mindy Magee, Mahesh N Samtani, Vikram Sinha, Kunal S Taskar, Vijay V Upreti, Jianning Yang, Jack Cook
Considerations for Industry-Preparing for the FDA Model-Informed Drug Development (MIDD) Paired Meeting Program. Clinical pharmacology and therapeutics (2024)
Karen Rowland Yeo, Eva Gil Bergland, Yuan Chen
Dose Optimization Informed by PBPK Modeling: State-of-the Art and Future. Clinical pharmacology and therapeutics (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Karen Rowland Yeo, Eva Gil Berglund, Yuan Chen
Dose Optimization Informed by PBPK Modeling: State-of-the Art and Future. Clinical pharmacology and therapeutics 116 (3) (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology 13 (4) (2024)
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Understanding CYP3A4 and P-gp mediated drug-drug interactions through PBPK modeling - Case example of pralsetinib. CPT: pharmacometrics & systems pharmacology (2024)
Yuan Chen, Fang Ma, Nicholas Jones, Rong Deng, Chunze Li, Chi-Chung Li
Assessment of CYP3A-mediated drug interaction via cytokine (IL-6) elevation for mosunetuzumab using physiologically-based pharmacokinetic modeling. CPT: pharmacometrics & systems pharmacology (2023)
Jialin Mao, Fang Ma, Jesse Yu, Tom De Bruyn, Miaoran Ning, Christine Bowman, Yuan Chen
Shared learning from a physiologically based pharmacokinetic modeling strategy for human pharmacokinetics prediction through retrospective analysis of Genentech compounds. Biopharmaceutics & drug disposition (2023)
Jianshuang Wang, Michael Van Parys, Lin Pan, Yuan Chen, Dorothy Cheung, Janine McKnight, Dennis Milanowski, Xiao Ding, Brian Dean
Determination of a novel antifibrotic small molecule GDC-3280 in human plasma and urine by liquid chromatography tandem mass spectrometry to support its first-in-human clinical trial. Biomedical chromatography : BMC 33 (4) (2019)
Yuan Chen, Rui Zhu, Fang Ma, Jialin Mao, Eugene C Chen, Edna F Choo, Srikumar Sahasranaman, Lichuan Liu
Assessment of OATP transporter-mediated drug-drug interaction using physiologically-based pharmacokinetic (PBPK) modeling - a case example. Biopharmaceutics & drug disposition 39 (9) (2018)