Clinical pharmacology and therapeutics

Keyphrases

Publications

volume 114, number 1, 2023

Iris K Minichmayr, D Max Smith, Kathleen M Giacomini, Piet H van der Graaf
Trends in Clinical Pharmacology and Therapeutics. Clinical pharmacology and therapeutics 114 (1) (2023)

volume 114, number 2, 2023

Shirley K Seo
External Control Arms: We're Not on Cruise Control Yet. Clinical pharmacology and therapeutics 114 (2) (2023)

volume 114, number 3, 2023

Yewon Choi, Alexander A Vinks, Piet H van der Graaf
Novel Therapeutic Modalities: The Future is Now. Clinical pharmacology and therapeutics 114 (3) (2023)

volume 114, number 4, 2023

Ingolf Cascorbi
Why is There Still Debate About Recommending DPYD-Testing Before Fluoropyrimidine Treatment? Clinical pharmacology and therapeutics 114 (4) (2023)

volume 114, number 5, 2023

Ingolf Cascorbi
Clinical Pharmacology of Cannabinoid Therapeutics: Drug Interactions and Side Effects. Clinical pharmacology and therapeutics 114 (5) (2023)

volume 114, number 6, 2023

D Max Smith, Iris K Minichmayr, Joseph F Standing, Kathleen M Giacomini, Piet H van der Graaf, Richard Wilson Peck
Ensuring Transparency and Quality of Clinical Trial Reporting in Clinical Pharmacology & Therapeutics: Prospective Trial Registration and Compliance with Reporting Guidelines Are Required for all Clinical Trials. Clinical pharmacology and therapeutics 114 (6) (2023)

volume 113, number 3, 2023

Guang Yang, Mrinal Mishra, Minoli A Perera
Multi-Omics Studies in Historically Excluded Populations: The Road to Equity. Clinical pharmacology and therapeutics 113 (3) (2023)
Demi L MacLennan, Jennifer L Plahovinsak, Rob J MacLennan, Carolynn Thomas Jones
Clinical Trial Site Perspectives and Practices on Study Participant Diversity and Inclusion. Clinical pharmacology and therapeutics 113 (3) (2023)
Demi L MacLennan, Jennifer L Plahovinsak, Rob J MacLennan, Carolynn Thomas Jones
Clinical Trial Site Perspectives and Practices on Study Participant Diversity and Inclusion. Clinical pharmacology and therapeutics 113 (3) (2023)
Ofra Barnett-Griness, Gad Rennert, Flavio Lejbkowicz, Mila Pinchev, Walid Saliba, Naomi Gronich
Association Between ABCG2, ABCB1, ABCC2 Efflux Transporter Single-Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real-Life Study. Clinical pharmacology and therapeutics 113 (3) (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Karthik Venkatakrishnan, Karen E Brown, Kathleen M Giacomini, Piet H van der Graaf
Diversity, Equity, and Inclusion: Translating Clinical Pharmacology for All. Clinical pharmacology and therapeutics 113 (3) (2023)
Ofra Barnett-Griness, Gad Rennert, Flavio Lejbkowicz, Mila Pinchev, Walid Saliba, Naomi Gronich
Association Between ABCG2, ABCB1, ABCC2 Efflux Transporter Single-Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real-Life Study. Clinical pharmacology and therapeutics 113 (3) (2023)
Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez
Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans. Clinical pharmacology and therapeutics 113 (3) (2023)
Alaina Webster
Transgender Individuals Deserve Compassionate, Personalized Care: A Transgender Patient Perspective. Clinical pharmacology and therapeutics 113 (3) (2023)
Amy L Corneli, Emily Hanlen-Rosado, Kevin McKenna, Richardae Araojo, Dawn Corbett, Kaveeta Vasisht, Bernadette Siddiqi, Tesheia Johnson, Luther T Clark, Sara B Calvert
Enhancing Diversity and Inclusion in Clinical Trials. Clinical pharmacology and therapeutics 113 (3) (2023)
Ofra Barnett-Griness, Gad Rennert, Flavio Lejbkowicz, Mila Pinchev, Walid Saliba, Naomi Gronich
Association Between ABCG2, ABCB1, ABCC2 Efflux Transporter Single-Nucleotide Variants and Irinotecan Adverse Effects in Patients With Colorectal Cancer: A Real-Life Study. Clinical pharmacology and therapeutics 113 (3) (2023)
Belén Valenzuela, Italo Poggesi, Nicolas Luyckx, Andrea Vaclavkova, Juan Jose Perez Ruixo
Pharmacokinetic-Pharmacodynamic Modeling of the Ponesimod Effect on Heart Rate in Patients With Multiple Sclerosis. Clinical pharmacology and therapeutics 113 (3) (2023)
Chiea Chuen Khor, Stefan Winter, Natalia Sutiman, Thomas E Mürdter, Sylvia Chen, Joanne Siok Liu Lim, Zheng Li, Jingmei Li, Kar-Seng Sim, Boian Ganchev, Diana Eccles, Bryony Eccles, William Tapper, Nathalie Khoueiry Zgheib, Arafat Tfayli, Raymond Chee Hui Ng, Yoon Sim Yap, Elaine Lim, Mabel Wong, Nan Soon Wong, Peter Cher Siang Ang, Rebecca Dent, Roman Tremmel, Kathrin Klein, Elke Schaeffeler, Yitian Zhou, Volker Martin Lauschke, Michel Eichelbaum, Matthias Schwab, Hiltrud B Brauch, Balram Chowbay, Werner Schroth
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations. Clinical pharmacology and therapeutics 113 (3) (2023)
Shalini V Mohan, Jamie Freedman
A Review of the Evolving Landscape of Inclusive Research and Improved Clinical Trial Access. Clinical pharmacology and therapeutics 113 (3) (2023)
Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez
Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans. Clinical pharmacology and therapeutics 113 (3) (2023)
Guimu Guo, Xiang You, Wanhong Wu, Jiarui Chen, Meng Ke, Rongfang Lin, Pinfang Huang, Cuihong Lin
Physiologically-Based Pharmacokinetic Modeling of Omalizumab to Predict the Pharmacokinetics and Pharmacodynamics in Pediatric Patients. Clinical pharmacology and therapeutics 113 (3) (2023)

volume 113, number 4, 2023

Sreenath M Krishnan, Lena E Friberg, Francois Mercier, Rong Zhang, Benjamin Wu, Jin Yan Jin, Tien Hoang, Marcus Ballinger, René Bruno, Mats O Karlson
Multistate Pharmacometric Model to Define the Impact of Second-Line Immunotherapies on the Survival Outcome of the IMpower131 Study. Clinical pharmacology and therapeutics 113 (4) (2023)
Trine Lauritzen, John Munkhaugen, Kari Peersen, Oscar Kristiansen, Elise Sverre, Shane D Nebauer, Maja Villseth, Anders M Andersen, Anja Camilla Svarstad, Elena Prunés Jensen, Stein Bergan, Einar Husebye, Nils Tore Vethe
Atorvastatin Metabolite Pattern in Skeletal Muscle and Blood from Patients with Coronary Heart Disease and Statin-Associated Muscle Symptoms. Clinical pharmacology and therapeutics 113 (4) (2023)
Richard Wyss, Joseph M Plasek, Li Zhou, Lily G Bessette, Sebastian G Schneeweiss, Jeremy A Rassen, Theodore Tsacogianis, Kueiyu Joshua Lin
Scalable Feature Engineering from Electronic Free Text Notes to Supplement Confounding Adjustment of Claims-Based Pharmacoepidemiologic Studies. Clinical pharmacology and therapeutics 113 (4) (2023)
Sanhita Sengupta, Ives Ntambwe, Katherine Tan, Qixing Liang, David Paulucci, Emily Castellanos, Joseph Fiore, Stephen Lane, Mariann Micsinai Balan, Kalyanee Viraswami-Apanna, Venkat Sethuraman, Meghna Samant, Ram Tiwari
Emulating Randomized Controlled Trials with Hybrid Control Arms in Oncology: A Case Study. Clinical pharmacology and therapeutics 113 (4) (2023)
Luana Colloca, Robert H Dworkin, John T Farrar, Leslie Tive, Jiyue Yang, Lars Viktrup, Gorana Dasic, Christine R West, Ed Whalen, Mark T Brown, Steven A Gilbert, Kenneth M Verburg
Predicting Treatment Responses in Patients With Osteoarthritis: Results From Two Phase III Tanezumab Randomized Clinical Trials. Clinical pharmacology and therapeutics 113 (4) (2023)
Piet H van der Graaf
Mush Room for Improving Therapeutic Approaches in Psychiatry. Clinical pharmacology and therapeutics 113 (4) (2023)
Frank Eektimmerman, Jesse J Swen, Alfons A den Broeder, Johanna M W Hazes, Fina S Kurreeman, Suzanne M M Verstappen, Nisha Nair, Andrzej Pawlik, Mike T Nurmohamed, Vita Dolžan, Stefan Böhringer, Cornelia F Allaart, Henk-Jan Guchelaar
Genome-wide Association Study of Methotrexate-Induced Liver Injury in Rheumatoid Arthritis Patients. Clinical pharmacology and therapeutics 113 (4) (2023)
Aaron S Devanathan, Julie B Dumond, Daijha J C Anderson, Kristen Moody, Amanda J Poliseno, Amanda P Schauer, Craig Sykes, Cynthia L Gay, Elias P Rosen, Angela D M Kashuba, Mackenzie L Cottrell
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots. Clinical pharmacology and therapeutics 113 (4) (2023)
Frank Eektimmerman, Jesse J Swen, Alfons A den Broeder, Johanna M W Hazes, Fina S Kurreeman, Suzanne M M Verstappen, Nisha Nair, Andrzej Pawlik, Mike T Nurmohamed, Vita Dolžan, Stefan Böhringer, Cornelia F Allaart, Henk-Jan Guchelaar
Genome-wide Association Study of Methotrexate-Induced Liver Injury in Rheumatoid Arthritis Patients. Clinical pharmacology and therapeutics 113 (4) (2023)
Yuki Kinoshita, Kazuhiro Kajiyama, Chieko Ishiguro, Takahiro Nonaka, Ryota Kimura, Yuki Kikuchi, Naoya Horiuchi, Toyotaka Iguchi, Yoshiaki Uyama
Characterizing Granulocytopenia Associated with Thiamazole in Patients with Hyperthyroidism Based on Real-World Data from the MID-NET in Japan. Clinical pharmacology and therapeutics 113 (4) (2023)
Aaron S Devanathan, Julie B Dumond, Daijha J C Anderson, Kristen Moody, Amanda J Poliseno, Amanda P Schauer, Craig Sykes, Cynthia L Gay, Elias P Rosen, Angela D M Kashuba, Mackenzie L Cottrell
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots. Clinical pharmacology and therapeutics 113 (4) (2023)
Yuki Kinoshita, Kazuhiro Kajiyama, Chieko Ishiguro, Takahiro Nonaka, Ryota Kimura, Yuki Kikuchi, Naoya Horiuchi, Toyotaka Iguchi, Yoshiaki Uyama
Characterizing Granulocytopenia Associated with Thiamazole in Patients with Hyperthyroidism Based on Real-World Data from the MID-NET in Japan. Clinical pharmacology and therapeutics 113 (4) (2023)
Jun-Ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean-Eric Charoin, Yoshikazu Ito, Sasha Sreckovic, Hiroyuki Takamori, Christoph Bucher, Yasutaka Ueda, Jules Hernández-Sánchez, Keisuke Gotanda, Gregor Jordan, Kenji Shinomiya, Julia Ramos, Jin Seok Kim, Jens Panse, Régis Peffault de Latour, Alexander Röth, Eiichi Morii, Hubert Schrezenmeier, Yoshitaka Isaka, Simona Sica, Yuzuru Kanakura, Sung-Soo Yoon, Taroh Kinoshita, Ido Paz-Priel, Alexandre Sostelly
Mitigating Drug-Target-Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors. Clinical pharmacology and therapeutics 113 (4) (2023)
Aaron S Devanathan, Julie B Dumond, Daijha J C Anderson, Kristen Moody, Amanda J Poliseno, Amanda P Schauer, Craig Sykes, Cynthia L Gay, Elias P Rosen, Angela D M Kashuba, Mackenzie L Cottrell
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots. Clinical pharmacology and therapeutics 113 (4) (2023)
Trine Lauritzen, John Munkhaugen, Kari Peersen, Oscar Kristiansen, Elise Sverre, Shane D Nebauer, Maja Villseth, Anders M Andersen, Anja Camilla Svarstad, Elena Prunés Jensen, Stein Bergan, Einar Husebye, Nils Tore Vethe
Atorvastatin Metabolite Pattern in Skeletal Muscle and Blood from Patients with Coronary Heart Disease and Statin-Associated Muscle Symptoms. Clinical pharmacology and therapeutics 113 (4) (2023)
Aaron S Devanathan, Julie B Dumond, Daijha J C Anderson, Kristen Moody, Amanda J Poliseno, Amanda P Schauer, Craig Sykes, Cynthia L Gay, Elias P Rosen, Angela D M Kashuba, Mackenzie L Cottrell
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots. Clinical pharmacology and therapeutics 113 (4) (2023)
Viktoriia Starokozhko, Fatima Tarrahi, Patrick J W S Vrijlandt, Peter G M Mol
Safety-Related Drug Label Changes Following Large Post-Marketing Cardiometabolic Trials: A Review of European Public Assessment Reports. Clinical pharmacology and therapeutics 113 (4) (2023)
Sanhita Sengupta, Ives Ntambwe, Katherine Tan, Qixing Liang, David Paulucci, Emily Castellanos, Joseph Fiore, Stephen Lane, Mariann Micsinai Balan, Kalyanee Viraswami-Apanna, Venkat Sethuraman, Meghna Samant, Ram Tiwari
Emulating Randomized Controlled Trials with Hybrid Control Arms in Oncology: A Case Study. Clinical pharmacology and therapeutics 113 (4) (2023)
Sreenath M Krishnan, Lena E Friberg, Francois Mercier, Rong Zhang, Benjamin Wu, Jin Yan Jin, Tien Hoang, Marcus Ballinger, René Bruno, Mats O Karlson
Multistate Pharmacometric Model to Define the Impact of Second-Line Immunotherapies on the Survival Outcome of the IMpower131 Study. Clinical pharmacology and therapeutics 113 (4) (2023)
Viktoriia Starokozhko, Fatima Tarrahi, Patrick J W S Vrijlandt, Peter G M Mol
Safety-Related Drug Label Changes Following Large Post-Marketing Cardiometabolic Trials: A Review of European Public Assessment Reports. Clinical pharmacology and therapeutics 113 (4) (2023)
Ahmed Abbas Suleiman, Aline Goebel, Sumit Bhatnagar, Ronilda D'Cunha, Wei Liu, Yinuo Pang
Population Pharmacokinetic and Exposure-Response Analyses for Efficacy and Safety of Risankizumab in Patients With Active Crohn's Disease. Clinical pharmacology and therapeutics 113 (4) (2023)
Richard Wyss, Joseph M Plasek, Li Zhou, Lily G Bessette, Sebastian G Schneeweiss, Jeremy A Rassen, Theodore Tsacogianis, Kueiyu Joshua Lin
Scalable Feature Engineering from Electronic Free Text Notes to Supplement Confounding Adjustment of Claims-Based Pharmacoepidemiologic Studies. Clinical pharmacology and therapeutics 113 (4) (2023)
Aaron S Devanathan, Julie B Dumond, Daijha J C Anderson, Kristen Moody, Amanda J Poliseno, Amanda P Schauer, Craig Sykes, Cynthia L Gay, Elias P Rosen, Angela D M Kashuba, Mackenzie L Cottrell
A Novel Algorithm to Improve PrEP Adherence Monitoring Using Dried Blood Spots. Clinical pharmacology and therapeutics 113 (4) (2023)
Luana Colloca, Robert H Dworkin, John T Farrar, Leslie Tive, Jiyue Yang, Lars Viktrup, Gorana Dasic, Christine R West, Ed Whalen, Mark T Brown, Steven A Gilbert, Kenneth M Verburg
Predicting Treatment Responses in Patients With Osteoarthritis: Results From Two Phase III Tanezumab Randomized Clinical Trials. Clinical pharmacology and therapeutics 113 (4) (2023)
Ahmed Abbas Suleiman, Aline Goebel, Sumit Bhatnagar, Ronilda D'Cunha, Wei Liu, Yinuo Pang
Population Pharmacokinetic and Exposure-Response Analyses for Efficacy and Safety of Risankizumab in Patients With Active Crohn's Disease. Clinical pharmacology and therapeutics 113 (4) (2023)
Jun-Ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean-Eric Charoin, Yoshikazu Ito, Sasha Sreckovic, Hiroyuki Takamori, Christoph Bucher, Yasutaka Ueda, Jules Hernández-Sánchez, Keisuke Gotanda, Gregor Jordan, Kenji Shinomiya, Julia Ramos, Jin Seok Kim, Jens Panse, Régis Peffault de Latour, Alexander Röth, Eiichi Morii, Hubert Schrezenmeier, Yoshitaka Isaka, Simona Sica, Yuzuru Kanakura, Sung-Soo Yoon, Taroh Kinoshita, Ido Paz-Priel, Alexandre Sostelly
Mitigating Drug-Target-Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors. Clinical pharmacology and therapeutics 113 (4) (2023)

volume 113, number 5, 2023

Kathleen M Giacomini
Biomarkers Come of Age in Clinical Pharmacology. Clinical pharmacology and therapeutics 113 (5) (2023)

volume 113, number 6, 2023

Piet H van der Graaf
Clinical Significance of Therapeutic Peptide and Protein Drug Interactions: A Call to Action. Clinical pharmacology and therapeutics 113 (6) (2023)