Zachary R Hunter (Zachary Hunter, Z R Hunter)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 29

Top Venues

Blood advances

Blood

British journal of haematology

American journal of hematology

Dana Farber Cancer Institute

Boston University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dana Farber Cancer Institute

United States

Instructor of Medicine :: Bing Center for Waldenström's Macroglobulinemia

Harvard Medical School

United States

Instructor of Medicine

Education History

Boston University

United States

PHD :: Pathology

Publications

Kris Richardson, Jorge J Castillo, Shayna R Sarosiek, Andrew R Branagan, Catherine A Flynn, Kirsten Meid, Joshua N Gustine, Xia Liu, Amanda Kofides, Shirong Liu, Julie L Wolf, Katherine A Kacena, Christopher J Patterson, Maria Luisa Guerrera, Nicholas Tsakmaklis, Steven P Treon, Zachary R Hunter
Identification of robust predictors for ibrutinib response by multiomics in MYD88-mutated Waldenström macroglobulinemia. Blood advances 8 (9) (2024)
Kris Richardson, Jorge J Castillo, Shayna R Sarosiek, Andrew R Branagan, Catherine A Flynn, Kirsten Meid, Joshua N Gustine, Xia Liu, Amanda Kofides, Shirong Liu, Julie L Wolf, Katherine A Kacena, Christopher J Patterson, Maria Luisa Guerrera, Nicholas Tsakmaklis, Steven P Treon, Zachary R Hunter
Identification of robust predictors for ibrutinib response by multiomics in MYD88-mutated Waldenström macroglobulinemia. Blood advances 8 (9) (2024)
Kris Richardson, Jorge J Castillo, Shayna Sarosiek, Andrew R Branagan, Catherine Flynn, Kirsten E Meid, Joshua Gutine, Xia Liu, Amanda Kofides, Shirong Liu, Julie L Wolf, Katherine Amy Kacena, Christopher J Patterson, Maria Luisa Guerrera, Nicholas Tsakmaklis, Steven P Treon, Zachary R Hunter
Identification of robust predictors for ibrutinib response by multi-omics in MYD88 mutated Waldenstrom Macroglobulinemia. Blood advances (2024)
M Munshi, X Liu, A Kofides, N Tsakmaklis, Zachary R Hunter, M L Guerrera, A Canning, J N Gustine, S Liu, J M Hatcher, J Chen, K Meid, Shayna R Sarosiek, C A Flynn, A R Branagan, G von Keudell, L M Palomba, Jorge J Castillo, G Yang, Steven P Treon
ERK1/2 pro-survival signalling is suppressed by pirtobrutinib in ibrutinib-resistant MYD88-mutated lymphoma cells. British journal of haematology (2024)
Kris Richardson, Jorge J Castillo, Shayna Sarosiek, Andrew R Branagan, Catherine Flynn, Kirsten E Meid, Joshua Gutine, Xia Liu, Amanda Kofides, Shirong Liu, Julie L Wolf, Katherine Amy Kacena, Christopher J Patterson, Maria Luisa Guerrera, Nicholas Tsakmaklis, Steven P Treon, Zachary R Hunter
Identification of robust predictors for ibrutinib response by multi-omics in MYD88 mutated Waldenstrom Macroglobulinemia. Blood advances (2024)
Jorge J Castillo, Andrew R Branagan, David Sermer, Catherine Flynn, Kirsten E Meid, Megan Little, Katherine Stockman, Timothy P White, Alexa G Canning, Maria Luisa Guerrera, Amanda Kofides, Shirong Liu, Xia Liu, Kris Richardson, Nicholas Tsakmaklis, Christopher J Patterson, Zachary R Hunter, Steven P Treon, Shayna Sarosiek
Ibrutinib and venetoclax as primary therapy in symptomatic treatment naïve Waldenström macroglobulinemia. Blood (2023)
Manit Munshi, Xia Liu, Amanda Kofides, Nickolas Tsakmaklis, Maria Luisa Guerrera, Zachary R Hunter, M Lia Palomba, Kimon V Argyropoulos, Christopher J Patterson, Alexa G Canning, Kirsten Meid, Joshua Gustine, Andrew R Branagan, Catherine A Flynn, Shayna Sarosiek, Jorge J Castillo, Jinhua Wang, Sara J Buhrlage, Nathanael S Gray, Nikhil C Munshi, Kenneth C Anderson, Steven P Treon, Guang Yang
A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas. Blood advances 6 (11) (2022)
Jorge J Castillo, Shayna R Sarosiek, Joshua N Gustine, Catherine A Flynn, Carly R Leventoff, Timothy P White, Kirsten Meid, Maria L Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Zachary R Hunter, Christopher J Patterson, Andrew R Branagan, Steven P Treon
Response and survival predictors in a cohort of 319 patients with Waldenström macroglobulinemia treated with ibrutinib monotherapy. Blood advances 6 (3) (2022)
Abdul-Hamid Bazarbachi, Hervé Avet-Loiseau, Raphael Szalat, Anil Aktas Samur, Zachary R Hunter, Masood A Shammas, Jill Corre, Mariateresa Fulciniti, Kenneth C Anderson, Giovanni Parmigiani, Steven P Treon, Mohamad Mohty, Nikhil C Munshi, Mehmet Kemal Samur
IgM-MM is predominantly a pre-germinal center disorder and has a distinct genomic and transcriptomic signature from WM. Blood 138 (20) (2021)
Jorge J Castillo, Kirsten Meid, Joshua N Gustine, Carly Leventoff, Timothy White, Catherine A Flynn, Shayna R Sarosiek, Maria G Demos, Maria L Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Lian Xu, Guang Yang, Andrew R Branagan, Elizabeth O'Donnell, Noopur Raje, Andrew J Yee, Christopher J Patterson, Zachary R Hunter, Steven P Treon
Long-term follow-up of ibrutinib monotherapy in treatment-naive patients with Waldenstrom macroglobulinemia. Leukemia (2021)
Joshua N Gustine, Lian Xu, Guang Yang, Xia Liu, Amanda Kofides, Nicholas Tsakmaklis, Manit Munshi, Maria Demos, Maria L Guerrera, Kirsten Meid, Christopher J Patterson, Shayna Sarosiek, Andrew R Branagan, Zachary R Hunter, Jorge J Castillo, Steven P Treon
Bone marrow involvement and subclonal diversity impairs detection of mutated CXCR4 by diagnostic next-generation sequencing in Waldenström macroglobulinaemia. British journal of haematology 194 (4) (2021)
Steven P Treon, Kirsten Meid, Zachary R Hunter, Catherine A Flynn, Shayna R Sarosiek, Carly R Leventoff, Timothy P White, Yang Cao, Aldo M Roccaro, Antonio Sacco, Maria G Demos, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Lian Xu, Christopher J Patterson, Manit Munshi, Nicholas Tsakmaklis, Guang Yang, Irene M Ghobrial, Andrew R Branagan, Jorge J Castillo
Phase 1 study of ibrutinib and the CXCR4 antagonist ulocuplumab in CXCR4-mutated Waldenström macroglobulinemia. Blood 138 (17) (2021)
Maria G Demos, Zachary R Hunter, Lian Xu, Nicholas Tsakmaklis, Amanda Kofides, Manit Munshi, Xia Liu, Maria Luisa Guerrera, Carly R Leventoff, Timothy P White, Catherine A Flynn, Kirsten Meid, Christopher J Patterson, Guang Yang, Andrew R Branagan, Shayna Sarosiek, Jorge J Castillo, Steven P Treon, Joshua N Gustine
Cell-free DNA analysis for detection of MYD88L265P and CXCR4S338X mutations in Waldenström macroglobulinemia. American journal of hematology 96 (7) (2021)
Jorge J Castillo, John N Allan, Tanya Siddiqi, Ranjana H Advani, Kirsten Meid, Carly Leventoff, Timothy P White, Catherine A Flynn, Shayna R Sarosiek, Andrew R Branagan, Maria G Demos, Maria L Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Lian Xu, Guang Yang, Christopher J Patterson, Zachary R Hunter, Matthew S Davids, Richard R Furman, Steven P Treon
Venetoclax in Previously Treated Waldenström Macroglobulinemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
Guang Yang, Jinhua Wang, Li Tan, Manit Munshi, Xia Liu, Amanda Kofides, Jiaji G Chen, Nicholas Tsakmaklis, Maria G Demos, Maria Luisa Guerrera, Lian Xu, Zachary R Hunter, Jianwei Che, Christopher J Patterson, Kirsten Meid, Jorge J Castillo, Nikhil C Munshi, Kenneth C Anderson, Michael D Cameron, Sara J Buhrlage, Nathanael S Gray, Steven P Treon
The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. Blood 138 (20) (2021)
Cristina Jiménez, Gloria G Chan, Lian Xu, Nickolas Tsakmaklis, Amanda Kofides, Maria G Demos, Jiaji Chen, Xia Liu, Manit Munshi, Guang Yang, Jorge J Castillo, Adrian Wiestner, Miriam Santero, Steven P Treon, Zachary R Hunter
Genomic evolution of ibrutinib-resistant clones in Waldenström macroglobulinaemia. British journal of haematology 189 (6) (2020)
Steven P Treon, Kirsten Meid, Joshua Gustine, Guang Yang, Lian Xu, Xia Liu, Christopher J Patterson, Zachary R Hunter, Andrew R Branagan, Jacob P Laubach, Irene M Ghobrial, Maria Lia Palomba, Ranjana H Advani, Jorge J Castillo
Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (6) (2020)
Jorge J Castillo, Gilad Itchaki, Joshua N Gustine, Kirsten Meid, Catherine A Flynn, Maria G Demos, Maria L Guerrera, Cristina Jimenez, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Christopher J Patterson, Lian Xu, Guang Yang, Zachary R Hunter, Steven P Treon
A matched case-control study comparing features, treatment and outcomes between patients with non-IgM lymphoplasmacytic lymphoma and Waldenström macroglobulinemia. Leukemia & lymphoma 61 (6) (2020)
Jorge J Castillo, Jithma A Abeykoon, Joshua N Gustine, Saurabh Zanwar, Kirsten Mein, Catherine A Flynn, Maria G Demos, Maria L Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nickolas Tsakmaklis, Rebecca King, Guang Yang, Zachary R Hunter, Ranjana H Advani, Maria Lia Palomba, Stephen M Ansell, Morie A Gertz, Prashant Kapoor, Steven P Treon
Partial response or better at six months is prognostic of superior progression-free survival in Waldenström macroglobulinaemia patients treated with ibrutinib. British journal of haematology 192 (3) (2020)
Jorge J Castillo, Joshua N Gustine, Kirsten Meid, Catherine A Flynn, Maria G Demos, Maria L Guerrera, Cristina Jimenez, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Christopher J Patterson, Lian Xu, Guang Yang, Zachary R Hunter, Steven P Treon
CXCR4 mutational status does not impact outcomes in patients with Waldenström macroglobulinemia treated with proteasome inhibitors. American journal of hematology 95 (4) (2020)
Lisa Marie Kaiser, Zachary R Hunter, Steven P Treon, Christian Buske
CXCR4 in Waldenström's Macroglobulinema: chances and challenges. Leukemia 35 (2) (2020)
Manit Munshi, Xia Liu, Jiaji G Chen, Lian Xu, Nickolas Tsakmaklis, Maria G Demos, Amanda Kofides, Maria Luisa Guerrera, Cristina Jimenez, Gloria G Chan, Zachary R Hunter, M Lia Palomba, Kimon V Argyropoulos, Kirsten Meid, Andrew Keezer, Joshua Gustine, Toni Dubeau, Jorge J Castillo, Christopher J Patterson, Jinhua Wang, Sara J Buhrlage, Nathanael S Gray, Steven P Treon, Guang Yang
SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas. Blood cancer journal 10 (1) (2020)
Joshua N Gustine, Lian Xu, Nicholas Tsakmaklis, Maria G Demos, Amanda Kofides, Jiaji G Chen, Xia Liu, Manit Munshi, Maria Luisa Guerrera, Gloria G Chan, Christopher J Patterson, Andrew Keezer, Kirsten Meid, Toni Dubeau, Guang Yang, Zachary R Hunter, Steven P Treon, Jorge J Castillo
CXCR4 S338X clonality is an important determinant of ibrutinib outcomes in patients with Waldenström macroglobulinemia. Blood advances 3 (19) (2020)
Zachary R Hunter, Lian Xu, Nickolas Tsakmaklis, Maria G Demos, Amanda Kofides, Cristina Jimenez, Gloria G Chan, Jiaji Chen, Xia Liu, Manit Munshi, Joshua Gustine, Kirsten Meid, Christopher J Patterson, Guang Yang, Toni Dubeau, Mehmet K Samur, Jorge J Castillo, Kenneth C Anderson, Nikhil C Munshi, Steven P Treon
Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia. Blood advances 2 (21) (2019)
Jorge J Castillo, David F Moreno, Maria I Arbelaez, Zachary R Hunter, Steven P Treon
CXCR4 mutations affect presentation and outcomes in patients with Waldenström macroglobulinemia: A systematic review. Expert review of hematology 12 (10) (2019)
Na Li, Michael A Lopez, María Linares, Subodh Kumar, Stefania Oliva, Joaquin Martinez-Lopez, Lian Xu, Tommaso Perini, William Senapedis, Erkan Baloglu, Masood A Shammas, Zachary R Hunter, Kenneth C Anderson, Steven P Treon, Nikhil C Munshi, Mariateresa Fulciniti
Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (1) (2018)
Jorge J Castillo, Kirsten Meid, Joshua N Gustine, Toni Dubeau, Patricia Severns, Zachary R Hunter, Guang Yang, Lian Xu, Steven P Treon
Prospective Clinical Trial of Ixazomib, Dexamethasone, and Rituximab as Primary Therapy in Waldenström Macroglobulinemia. Clinical cancer research : an official journal of the American Association for Cancer Research 24 (14) (2018)
Mateja Manček-Keber, Duško Lainšček, Mojca Benčina, Steven P Treon, Rok Romih, Zachary R Hunter, Roman Jerala
Extracellular vesicle-mediated transfer of constitutively active MyD88L265P engages MyD88wt and activates signaling. Blood 131 (15) (2018)
Zachary R Hunter, Lian Xu, Guang Yang, Nicholas Tsakmaklis, Josephine M Vos, Xia Liu, Jie Chen, Robert J Manning, Jiaji G Chen, Philip Brodsky, Christopher J Patterson, Joshua Gustine, Toni Dubeau, Jorge J Castillo, Kenneth C Anderson, Nikhil M Munshi, Steven P Treon
Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia. Blood 128 (6) (2016)
Jorge J Castillo, Adam J Olszewski, Zachary R Hunter, Sandra Kanan, Kirsten Meid, Steven P Treon
Incidence of secondary malignancies among patients with Waldenström macroglobulinemia: An analysis of the SEER database. Cancer 121 (13) (2015)

Zachary R Hunter.css-eqlu8i{font-size:small;padding-left:4px;} (Zachary Hunter, Z R Hunter)

Publication Activity (10 Years)

Top Topics

Top Venues

Zachary R Hunter (Zachary Hunter, Z R Hunter)