Irene M Ghobrial (Irene Ghobrial)

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 27

Top Topics

Multiple Myeloma

Top Venues

Nature nanotechnology

Nature communications

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Blood cancer journal

This page only lists publications with an associated author ORCID identifier.

Publications

Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology 18 (2) (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology 18 (2) (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology 18 (2) (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology 18 (2) (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology 18 (2) (2023)
Alexandre Detappe, Hung V-T Nguyen, Yivan Jiang, Michael P Agius, Wencong Wang, Clelia Mathieu, Nang K Su, Samantha L Kristufek, David J Lundberg, Sachin Bhagchandani, Irene M Ghobrial, P Peter Ghoroghchian, Jeremiah A Johnson
Author Correction: Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma. Nature nanotechnology (2023)
Tarek H Mouhieddine, Chidimma Nzerem, Robert A Redd, Andrew Dunford, Matthew J Leventhal, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Habib El-Khoury, David P Steensma, Benjamin L Ebert, Robert J Soiffer, Jonathan J Keats, Shaadi Mehr, Daniel Auclair, Irene M Ghobrial, Adam S Sperling, Chip Stewart, Gad A Getz
Clinical outcomes and evolution of clonal hematopoiesis in patients with newly diagnosed multiple myeloma. Cancer research communications (2023)
Rebecca Boiarsky, Nicholas J Haradhvala, Jean-Baptiste Alberge, Romanos Sklavenitis-Pistofidis, Tarek H Mouhieddine, Oksana Zavidij, Ming-Chieh Shih, Danielle Firer, Mendy Miller, Habib El-Khoury, Shankara K Anand, François Aguet, David A Sontag, Irene M Ghobrial, Gad A Getz
Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis. Nature communications 13 (1) (2022)
Andrew T Hutchinson, Jean-Baptiste Alberge, Romanos Sklavenitis-Pistofidis, Elizabeth D Lightbody, Gad A Getz, Irene M Ghobrial
Single-cell profiling of tumour evolution in multiple myeloma - opportunities for precision medicine. Nature reviews. Clinical oncology 19 (4) (2022)
Anna S Nam, Neville Dusaj, Franco Izzo, Rekha Murali, Robert M Myers, Tarek H Mouhieddine, Jesus Sotelo, Salima Benbarche, Michael Waarts, Federico Gaiti, Sabrin Tahri, Ross L Levine, Omar Abdel-Wahab, Lucy A Godley, Ronan Chaligné, Irene M Ghobrial, Dan A Landau
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation. Nature genetics 54 (10) (2022)
Elias Campo, Elaine S Jaffe, James R Cook, Leticia Quintanilla-Martínez, Steven H Swerdlow, Kenneth C Anderson, Pierre Brousset, Lorenzo Cerroni, Laurence de Leval, Stefan Dirnhofer, Ahmet Dogan, Andrew L Feldman, Falko Fend, Jonathan W Friedberg, Philippe Gaulard, Paolo Ghia, Steven M Horwitz, Rebecca L King, Gilles Andre Salles, Jesús San F Miguel, John Francis Seymour, Steven P Treon, Julie M Vose, Emanuele Zucca, Ranjana Advani, Stephen Ansell, Wing-Yan Au, Carlos Barrionuevo, Peter Leif Bergsagel, Wing C Chan, Jeffrey I Cohen, Francesco d'Amore, Andrew John Davies, Brunangelo Falini, Irene M Ghobrial, Mariusz A Wasik, John G Gribben, Eric D Hsi, Brad S Kahl, Won-Seog Kim, Shaji K Kumar, Ann Steward LaCasce, Camille Laurent, Georg Lenz, John P Leonard, Michael P Link, Armando Lopez-Guillermo, Maria-Victoria Mateos-Manteca, Elizabeth A Macintyre, Ari M Melnick, Judith Trotman, Shigeo Nakamura, Marina Narbaitz, Astrid Pavlovsky, Stefano A Pileri, Miguel Angel Piris, Barbara Pro, Vincent Rajkumar, Steven T Rosen, Birgitta Sander, Laurie Sehn, Margaret A Shipp, Sonali M Smith, Louis M Staudt, Catherine Thieblemont, Thomas Tousseyn, Wyndham H Wilson, Tadashi Yoshino, Pier Luigi Luigi Zinzani, Martin Dreyling, David W Scott, Jane N Winter, Andrew D Zelenetz
The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee. Blood 140 (11) (2022)
Mark Bustoros, Shankara Anand, Romanos Sklavenitis-Pistofidis, Robert A Redd, Eileen Mary Boyle, Benny Zhitomirsky, Andrew J Dunford, Yu-Tzu Tai, Selina J Chavda, Cody Boehner, Carl Jannes Neuse, Mahshid Rahmat, Andrew T Hutchinson, Tineke Casneuf, Raluca Verona, Efstathis Kastritis, Lorenzo Trippa, Chip Stewart, Brian A Walker, Faith E Davies, Meletios- Athanasios Dimopoulos, Peter Leif Bergsagel, Kwee L Yong, Gareth J Morgan, François Aguet, Gad A Getz, Irene M Ghobrial
Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes. Nature communications 13 (1) (2022)
Andrew T Hutchinson, Jean-Baptiste Alberge, Elizabeth D Lightbody, Cody J Boehner, Andrew Dunford, Romanos Sklavenitis-Pistofidis, Tarek H Mouhieddine, Annie N Cowan, Nang Kham Su, Erica M Horowitz, Hadley Barr, Laura Hevenor, Jenna B Beckwith, Jacqueline Perry, Amanda Cao, Ziao Lin, Frank K Kuhr, Richard G Del Mastro, Omar Nadeem, Patricia T Greipp, Chip Stewart, Daniel Auclair, Gad A Getz, Irene M Ghobrial
MinimuMM-seq: Genome sequencing of circulating tumor cells for minimally invasive molecular characterization of multiple myeloma pathology. Cancer discovery (2022)
Elizabeth K O' Donnell, Yael N Shapiro, Andrew J Yee, Omar Nadeem, Jacob P Laubach, Andrew R Branagan, Kenneth C Anderson, Clifton C Mo, Nikhil C Munshi, Irene M Ghobrial, Adam S Sperling, Emerentia A Agyemang, Jill N Burke, Cynthia C Harrington, Bonnie Y Hu, Paul G Richardson, Noopur S Raje, Areej El-Jawahri
Quality of life, psychological distress, and prognostic perceptions in caregivers of patients with multiple myeloma. Blood advances 6 (17) (2022)
Romanos Sklavenitis-Pistofidis, Nicholas J Haradhvala, Gad A Getz, Irene M Ghobrial
Inflammatory stromal cells in the myeloma microenvironment. Nature immunology 22 (6) (2021)
Romanos Sklavenitis-Pistofidis, Gad A Getz, Irene M Ghobrial
Single-cell RNA sequencing: one step closer to the clinic. Nature medicine 27 (3) (2021)
Simon Mendez-Ferrer, Dominique Bonnet, David P Steensma, Robert P Hasserjian, Irene M Ghobrial, John G Gribben, Michael Andreeff, Daniela S Krause
Bone marrow niches in haematological malignancies. Nature reviews. Cancer 20 (5) (2020)
Steven P Treon, Kirsten Meid, Joshua Gustine, Guang Yang, Lian Xu, Xia Liu, Christopher J Patterson, Zachary R Hunter, Andrew R Branagan, Jacob P Laubach, Irene M Ghobrial, Maria Lia Palomba, Ranjana H Advani, Jorge J Castillo
Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (6) (2020)
Catherine R Marinac, Irene M Ghobrial, Brenda M Birmann, Jenny Soiffer, Timothy R Rebbeck
Dissecting racial disparities in multiple myeloma. Blood cancer journal 10 (2) (2020)
Carl Jannes Neuse, Oliver C Lomas, Christoph Schliemann, Yu Jia Shen, Salomon Manier, Mark Bustoros, Irene M Ghobrial
Genome instability in multiple myeloma. Leukemia 34 (11) (2020)
Tarek H Mouhieddine, Adam S Sperling, Robert A Redd, Jihye Park, Matthew Leventhal, Christopher J Gibson, Salomon Manier, Amin H Nassar, Marzia Capelletti, Daisy Huynh, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Kalvis Hornburg, Henry Dumke, Muhieddine M Itani, Cody J Boehner, Chia-Jen Liu, Saud H AlDubayan, Brendan Reardon, Eliezer M Van Allen, Jonathan J Keats, Chip Stewart, Shaadi Mehr, Daniel Auclair, Robert L Schlossman, Nikhil C Munshi, Kenneth C Anderson, David P Steensma, Jacob P Laubach, Paul G Richardson, Jerome Ritz, Benjamin L Ebert, Robert J Soiffer, Lorenzo Trippa, Gad A Getz, Donna S Neuberg, Irene M Ghobrial
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nature communications 11 (1) (2020)
Mark Bustoros, Efstathios Kastritis, Romanos Sklavenitis-Pistofidis, Chia-Jen Liu, Kalvis Hornburg, Nikolaos Kanellias, Geon Kim, David Liu, Maria Gavriatopoulou, Catherine R Marinac, Maria Roussou, Magdalini Migkou, Kimberly Noonan, Kaitlen Reyes, Bradley Rivotto, Carl Jannes Neuse, Dimitrios C Ziogas, Jacob Laubach, Evangelos Terpos, Kenneth C Anderson, Paul G Richardson, Irene M Ghobrial, Meletios- Athanasios Dimopoulos
Bone marrow biopsy in low-risk monoclonal gammopathy of undetermined significance reveals a novel smoldering multiple myeloma risk group. American journal of hematology 94 (5) (2019)
Salomon Manier, Daisy Huynh, Yu J Shen, Jia Zhou, Timur Yusufzai, Karma Z Salem, Richard Y Ebright, Jiantao Shi, Jihye Park, Siobhan V Glavey, William G Devine, Chia-Jen Liu, Xavier Leleu, Bruno Quesnel, Catherine Roche-Lestienne, John K Snyder, Lauren E Brown, Nathanael Gray, James E Bradner, Luke Whitesell, John A Porco, Irene M Ghobrial
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma. Science translational medicine 9 (389) (2018)