An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations.
Jesse BoumelhaSophie de Carné TrécessonEmily K LawPablo Romero-ClavijoMatthew A CoelhoKevin W NgEdurne MugarzaChristopher MooreSareena RanaDeborah R CaswellMiguel MurilloDavid C HancockProkopios P ArgyrisWilliam L BrownCameron DurfeeLindsay K LarsonRachel Isaksson VogelAlejandro Suarez-BonnetSimon Lawrence PriestnallPhilip EastSarah J RossGeorge KassiotisMiriam Molina-ArcasCharles SwantonReuben Stewart HarrisJulian DownwardPublished in: Cancer research (2022)
This study develops a mouse model of immunogenic KRAS-mutant lung cancer to facilitate the investigation of optimal combinations of targeted therapies with immunotherapies.
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