Small-quantity lipid-based nutrient supplements for children age 6-24 months: a systematic review and individual participant data meta-analysis of effects on developmental outcomes and effect modifiers.

Elizabeth L Prado Charles D Arnold K Ryan Wessells Christine P Stewart Souheila Abbeddou Seth Adu-Afarwuah Benjamin F Arnold Ulla Ashorn Per Ashorn Elodie Becquey Kenneth H Brown Jaya Chandna Parul ChristianHolly N DentzSherlie J L DulienceLia C H Fernald Emanuela Galasso Lotta Hallamaa Sonja Y Hess Lieven Huybregts Lora L IannottiElizabeth Y JimenezPatricia KohlAnna Lartey Agnes Le PortStephen P LubyKenneth M Maleta Andrew Matchado Susana L Matias Malay Kanti Mridha Robert Ntozini Clair Null Maku E Ocansey Sarker Masud Parvez John Phuka Amy J Pickering Andrew J PrendergastAbu A ShamimZakia SiddiquiFahmida Tofail Ann M WeberLee S F WuKathryn G Dewey

Published in: The American journal of clinical nutrition (2021)

Child SQ-LNSs can be expected to result in modest developmental gains, which would be analogous to 1-1.5 IQ points on an IQ test, particularly in populations with a high child stunting burden. Certain groups of children who experience higher-risk environments have greater potential to benefit from SQ-LNSs in developmental outcomes.This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42020159971.

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