Ethics of a therapeutic trial: addressing limitations of an active intervention in optic nerve lymphoma.
Rohan Bir SinghSahil ThakurParul IchhpujaniSuresh KumarPublished in: BMJ case reports (2018)
We report a unique case of optic nerve lymphoma after completion of chemotherapy for non-Hodgkin's lymphoma. The uncommon nature of presentation, our therapeutic dilemma and the further course of treatment are reported. In cases with extremely poor prognosis, unnecessary treatment puts additional strain both financially and psychologically on the patients and their family. Therapeutic focus should be on hospice care and family counselling. The decision to not treat is a crucial component of cancer management; however, the ethics of this decision are yet to be suitably addressed by the literature.
Keyphrases
- optic nerve
- poor prognosis
- diffuse large b cell lymphoma
- public health
- palliative care
- end stage renal disease
- long non coding rna
- optical coherence tomography
- randomized controlled trial
- healthcare
- chronic kidney disease
- clinical trial
- newly diagnosed
- systematic review
- big data
- decision making
- ejection fraction
- study protocol
- peritoneal dialysis
- locally advanced
- quality improvement
- radiation therapy
- pain management
- rectal cancer
- global health
- machine learning
- case report
- hodgkin lymphoma
- chronic pain
- open label