Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1.

Yang JiaoTanya WattsJing XueBethany HannafonWei-Qun Ding

Published in: BMC cancer (2018)

We demonstrate that sorafenib attenuates DHA-induced HO-1 expression and acts in synergy with DHA to suppress cancer cell viability and tumor growth. Considering the known health benefits of DHA and the clinical effectiveness of Sorafenib, their combination is an attractive therapeutic strategy against cancer.

Keyphrases

papillary thyroid
squamous cell
fatty acid
randomized controlled trial
poor prognosis
mental health
young adults
high glucose
signaling pathway
climate change
drug induced
human health