Anti-citrullinated peptide antibodies are the strongest predictor of clinically relevant radiographic progression in rheumatoid arthritis patients achieving remission or low disease activity: A post hoc analysis of a nationwide cohort in Japan.

Tomohiro KogaAkitomo OkadaTakaaki FukudaToshihiko HidakaTomonori IshiiYukitaka UekiTakao KoderaMunetoshi NakashimaYuichi TakahashiSeiyo HondaYoshiro HoraiRyu WatanabeHiroshi OkunoToshiyuki AramakiTomomasa IzumiyamaOsamu TakaiTaiichiro MiyashitaShuntaro SatoShin-Ya KawashiriNaoki IwamotoKunihiro IchinoseMami TamaiTomoki OriguchiHideki NakamuraKiyoshi AoyagiKatsumi EguchiAtsushi Kawakaminull null

Published in: PloS one (2017)

ACPA positivity was the strongest independent predictor of CRRP in patients with RA in remission or LDA. Physicians should recognize ACPA as a poor-prognosis factor regarding the radiographic outcome of RA, even among patients showing a clinically favorable response to DMARDs.

Keyphrases

disease activity
rheumatoid arthritis patients
poor prognosis
rheumatoid arthritis
systemic lupus erythematosus
long non coding rna
ankylosing spondylitis
juvenile idiopathic arthritis
primary care
cross sectional
idiopathic pulmonary fibrosis
ulcerative colitis