A systematic review of variations in circadian rhythm genes and type 2 diabetes.
Harry StevensGiulia VerdoneLeonie LangCatherine GrahamLeta PilicYiannis MavrommatisPublished in: Nutrition and health (2023)
Individuals with variations in melatonin receptor 1B, brain and muscle arnt-like 1 and PER may be at higher risk of type 2 diabetes. Further research is needed regarding other circadian rhythm genes. More longitudinal studies and randomised trials are required before clinical recommendations can be made.
Keyphrases
- type diabetes
- genome wide
- atrial fibrillation
- clinical trial
- bioinformatics analysis
- genome wide identification
- heart rate
- skeletal muscle
- white matter
- cardiovascular disease
- glycemic control
- insulin resistance
- genome wide analysis
- clinical practice
- cross sectional
- randomized controlled trial
- multiple sclerosis
- blood pressure
- adipose tissue
- transcription factor
- cerebral ischemia
- metabolic syndrome
- blood brain barrier