Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome.
Katriona GoldmannAthina SpiliopoulouAndrii IakovlievDarren PlantNisha NairCankut Cubuknull nullPaul M McKeigueMichael R BarnesRichard B WarrenCostantino PitzalisMyles J LewisPublished in: Annals of the rheumatic diseases (2023)
SNP rs3128921 could potentially be used to stratify patients to more aggressive treatment immediately at diagnosis.
Keyphrases
- genome wide
- rheumatoid arthritis
- end stage renal disease
- chronic kidney disease
- ejection fraction
- poor prognosis
- newly diagnosed
- dna methylation
- copy number
- prognostic factors
- gene expression
- long non coding rna
- high density
- binding protein
- interstitial lung disease
- combination therapy
- smoking cessation
- replacement therapy