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A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies.

Aparna HegdePriyamvada JayaprakashColine A CouillaultSarina Piha-PaulDaniel KarpJordi RodonShubham PantSiqing FuEcaterina E DumbravaTimothy Anthony YapVivek SubbiahPriya R BhosaleCristian CoarfaJack P HigginsEric T WilliamsThomas F WilsonJoAnn LimFunda Meric-BernstamElizabeth SumnerHira ZainDi NguyenLy M NguyenKimal RajapaksheMichael A CurranDavid S Hong
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
No new or unexpected safety signals were observed from combining evofosfamide and ipilimumab, and evidence of therapeutic activity was noted.
Keyphrases
  • open label
  • clinical trial
  • randomized controlled trial
  • placebo controlled