Timothy Anthony Yap (Timothy A Yap, Timothy Yap)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 72

Top Topics

Advanced Cancer

Histone Deacetylase

Dna Damage Response

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Cancer discovery

Nature medicine

JCO precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael S Nakazawa, Ian M Silverman, Victoria Rimkunas, Artur Veloso, Dominik Głodzik, Adrienne Johnson, Toshiro K Ohsumi, Shreyaskumar R Patel, Anthony P Conley, Christina Lynn Roland, Pamela T Soliman, Hannah C Beird, Chia-Chin Wu, Davis R Ingram, Rossana Lazcano, Dawon Song, Khalida M Wani, Alexander J F Lazar, Timothy Anthony Yap, Wei-Lien Wang, Jonathan A Livingston
Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Molecular cancer therapeutics (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Natalie Yan Li Ngoi, Patrick G Pilié, Daniel J McGrail, Michal Zimmermann, Katharina Schlacher, Timothy Anthony Yap
Targeting ATR in patients with cancer. Nature reviews. Clinical oncology (2024)
Michael S Nakazawa, Ian M Silverman, Victoria Rimkunas, Artur Veloso, Dominik Głodzik, Adrienne Johnson, Toshiro K Ohsumi, Shreyaskumar R Patel, Anthony P Conley, Christina Lynn Roland, Pamela T Soliman, Hannah C Beird, Chia-Chin Wu, Davis R Ingram, Rossana Lazcano, Dawon Song, Khalida M Wani, Alexander J F Lazar, Timothy Anthony Yap, Wei-Lien Wang, Jonathan A Livingston
Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Molecular cancer therapeutics 23 (7) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Natalie I Vokes, Xiuning Li, Timothy Anthony Yap
PIKing up and AKTing on resistance mutations in osimertinib-treated EGFR-mutated NSCLC. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Timothy Anthony Yap, Anthony W Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltan Szucs, Ioannis Gounaris, Johann S de Bono
First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Carlos Torrado, Ruth Plummer, Timothy Anthony Yap
Poly(ADP-Ribose) Polymerase Inhibitor Development: Promising Strategies to Move Beyond Approved Indications. JCO precision oncology 8 (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Timothy Anthony Yap, Anthony W Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltan Szucs, Ioannis Gounaris, Johann S de Bono
First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated (ATM) loss of function displays variant and tissue-specific differences across tumor types. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Timothy Anthony Yap, Anthony W Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltan Szucs, Ioannis Gounaris, Johann S de Bono
First-in-Human Study of the Ataxia Telangiectasia and Rad3-related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Timothy Anthony Yap, Anthony W Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltan Szucs, Ioannis Gounaris, Johann S de Bono
First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers. Cancer discovery (2024)
Natalie Yan Li Ngoi, Patrick G Pilié, Daniel J McGrail, Michal Zimmermann, Katharina Schlacher, Timothy Anthony Yap
Targeting ATR in patients with cancer. Nature reviews. Clinical oncology 21 (4) (2024)
Michael S Nakazawa, Ian M Silverman, Victoria Rimkunas, Artur Veloso, Dominik Głodzik, Adrienne Johnson, Toshiro K Ohsumi, Shreyaskumar R Patel, Anthony P Conley, Christina Lynn Roland, Pamela T Soliman, Hannah C Beird, Chia-Chin Wu, Davis R Ingram, Rossana Lazcano, Dawon Song, Khalida M Wani, Alexander J F Lazar, Timothy Anthony Yap, Wei-Lien Wang, Jonathan A Livingston
Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Molecular cancer therapeutics 23 (7) (2024)
Timothy Anthony Yap, Anthony W Tolcher, Ruth Plummer, Jatinder Kaur Mukker, Marta Enderlin, Christine Hicking, Thomas Grombacher, Giuseppe Locatelli, Zoltan Szucs, Ioannis Gounaris, Johann S de Bono
First-in-Human Study of the Ataxia Telangiectasia and Rad3-Related (ATR) Inhibitor Tuvusertib (M1774) as Monotherapy in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Michael S Nakazawa, Ian M Silverman, Victoria Rimkunas, Artur Veloso, Dominik Głodzik, Adrienne Johnson, Toshiro K Ohsumi, Shreyaskumar R Patel, Anthony P Conley, Christina Lynn Roland, Pamela T Soliman, Hannah C Beird, Chia-Chin Wu, Davis R Ingram, Rossana Lazcano, Dawon Song, Khalida M Wani, Alexander J F Lazar, Timothy Anthony Yap, Wei-Lien Wang, Jonathan A Livingston
Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Molecular cancer therapeutics (2024)
Carlos Torrado, Ruth Plummer, Timothy Anthony Yap
Poly(ADP-Ribose) Polymerase Inhibitor Development: Promising Strategies to Move Beyond Approved Indications. JCO precision oncology 8 (2024)
Natalie Yan Li Ngoi, Patrick G Pilié, Daniel J McGrail, Michal Zimmermann, Katharina Schlacher, Timothy Anthony Yap
Targeting ATR in patients with cancer. Nature reviews. Clinical oncology 21 (4) (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers. Cancer discovery (2024)
Guang Lei, Chao Mao, Amber D Horbath, Yuelong Yan, Shirong Cai, Yao Jun, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei-Kuang Chen, Anagha Alapati, Timothy Anthony Yap, Mien-Chie Hung, Mingjian James You, Helen Piwnica-Worms, Boyi Gan
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer discovery 14 (8) (2024)
Lilie L Lin, Franklin Wong, Ruitao Lin, Timothy Anthony Yap, Jennifer K Litton
Pharmacodynamic Activity of [ 18 F]-Fluorthanatrace Poly(ADP-ribose) Polymerase Positron Emission Tomography in Patients With BRCA1/2 -Mutated Breast Cancer Receiving Talazoparib. JCO precision oncology 8 (2024)
Michael S Nakazawa, Ian M Silverman, Victoria Rimkunas, Artur Veloso, Dominik Głodzik, Adrienne Johnson, Toshiro K Ohsumi, Shreyaskumar R Patel, Anthony P Conley, Christina Lynn Roland, Pamela T Soliman, Hannah C Beird, Chia-Chin Wu, Davis R Ingram, Rossana Lazcano, Dawon Song, Khalida M Wani, Alexander J F Lazar, Timothy Anthony Yap, Wei-Lien Wang, Jonathan A Livingston
Loss of the DNA Repair Gene RNase H2 Identifies a Unique Subset of DDR-Deficient Leiomyosarcomas. Molecular cancer therapeutics 23 (7) (2024)
Roberto Carmagnani Pestana, Justin Tyler Moyers, Jason Roszik, Shiraj Sen, David S Hong, Aung Naing, Cynthia E Herzog, Siqing Fu, Sarina A Piha-Paul, Jordi Rodon Ahnert, Timothy Anthony Yap, Daniel D Karp, Apostolia-Maria Tsimberidou, Shubham Pant, Maria Alejandra Zarzour, Ravin Ratan, Vinod Ravi, Robert S Benjamin, Alexander J F Lazar, Wei-Lien Wang, Najat C Daw, Jonathan D Gill, Douglas J Harrison, Valerae O Lewis, Christina Lynn Roland, Shreyaskumar R Patel, Jonathan A Livingston, Neeta Somaiah, Joseph A Ludwig, Anthony P Conley, Nelson Hammerschlak, Richard G Gorlick, Funda Meric-Bernstam, Vivek Subbiah
Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Niamh Coleman, Timothy Anthony Yap, John Victor Heymach, Funda Meric-Bernstam, Xiuning Li
Antibody-drug conjugates in lung cancer: dawn of a new era? NPJ precision oncology 7 (1) (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
Funda Meric-Bernstam, James M Ford, Peter J O'Dwyer, Geoffrey I Shapiro, Lisa Meier McShane, Boris Freidlin, Roisin E O'Cearbhaill, Suzanne George, Julia L Glade Bender, Gary H Lyman, James V Tricoli, David R Patton, Stanley R Hamilton, Robert C Gray, Douglas S Hawkins, Bhanumati Ramineni, Keith T Flaherty, Petros D Grivas, Timothy Anthony Yap, Jordan D Berlin, James H Doroshow, Lyndsay N Harris, Jeffrey A Moscow
National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Niamh Coleman, Timothy Anthony Yap, John Victor Heymach, Funda Meric-Bernstam, Xiuning Li
Antibody-drug conjugates in lung cancer: dawn of a new era? NPJ precision oncology 7 (1) (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine (2023)
Ezra Y Rosen, Timothy Anthony Yap, Elizabeth K Lee, Martin Højgaard, Niharika B Mettu, Stéphanie Lheureux, Benedito Arruda Carneiro, Ruth Plummer, Adrian J Fretland, Danielle Ulanet, Yi Xu, Robin McDougall, Maria Koehler, Elisa Fontana
Development of a Practical Nomogram for Personalized Anemia Management in Patients Treated with Ataxia Telangiectasia and Rad3-related (ATR) Inhibitor Camonsertib. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
Alexander E Drilon, Manish R Sharma, Melissa Lynne Johnson, Timothy Anthony Yap, Shirish M Gadgeel, Dale Nepert, Gang Feng, Micaela B Reddy, Allison S Harney, Mohamed S A Elsayed, Adam W Cook, Christina E Wong, Ronald J Hinklin, Yutong Jiang, Eric N Brown, Nickolas A Neitzel, Ellen R Laird, Wen-I Wu, Anurag Singh, Ping Wei, Keith A Ching, John J Gaudino, Patrice A Lee, Dylan P Hartley, S Michael Rothenberg
SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy. Cancer discovery (2023)
Timothy P DiPeri, Kurt W Evans, Maria Gabriela Raso, Ming Zhao, Yasmeen Q Rizvi, Xiaofeng Zheng, Bailiang Wang, Bryce P Kirby, Kathleen Kong, Michael Kahle, Timothy Anthony Yap, Ecaterina E Ileana Dumbrava, Jaffer A Ajani, Siqing Fu, Khandan Keyomarsi, Funda Meric-Bernstam
Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Timothy Anthony Yap, Elisa Fontana, Elizabeth K Lee, David R Spigel, Martin Højgaard, Stephanie Lheureux, Niharika B Mettu, Benedito A Carneiro, Louise Carter, Ruth Plummer, Gregory M Cote, Funda Meric-Bernstam, Joseph O'Connell, Joseph D Schonhoft, Marisa Wainszelbaum, Adrian J Fretland, Peter Manley, Yi Xu, Danielle Ulanet, Victoria Rimkunas, Mike Zinda, Maria Koehler, Ian M Silverman, Jorge Sergio Reis-Filho, Ezra Rosen
Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results. Nature medicine (2023)
Deepak Bhamidipati, Jaime I Haro-Silerio, Timothy Anthony Yap, Natalie Ngoi
PARP inhibitors: enhancing efficacy through rational combinations. British journal of cancer (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine 29 (1) (2023)
Omar Alhalabi, Roman Groisberg, Ralph Zinner, Andrew W Hahn, Aung Naing, Shizhen Zhang, Apostolia-Maria Tsimberidou, Jordi Rodon, Siqing Fu, Timothy Anthony Yap, David S Hong, Ming Sun, Yunfang Jiang, Shubham Pant, Amishi Y Shah, Amado J Zurita, Nizar M Tannir, Raghunandan Vikram, Jason Roszik, Funda Meric-Bernstam, Vivek Subbiah
Phase I study of sapanisertib with carboplatin and paclitaxel in mTOR pathway altered solid malignancies. NPJ precision oncology 7 (1) (2023)
Funda Meric-Bernstam, James M Ford, Peter J O'Dwyer, Geoffrey I Shapiro, Lisa Meier McShane, Boris Freidlin, Roisin E O'Cearbhaill, Suzanne George, Julia L Glade Bender, Gary H Lyman, James V Tricoli, David R Patton, Stanley R Hamilton, Robert C Gray, Douglas S Hawkins, Bhanumati Ramineni, Keith T Flaherty, Petros D Grivas, Timothy Anthony Yap, Jordan D Berlin, James H Doroshow, Lyndsay N Harris, Jeffrey A Moscow
National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Stephen J Pettitt, Nan Shao, Diana Zatreanu, Jessica Frankum, Ilirjana Bajrami, Rachel Brough, Dragomir B Krastev, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Sonja Lorenz, Alistair Rust, Johann S de Bono, Timothy Anthony Yap, Andrew N J Tutt, Christopher J Lord
A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-∆11q splice variant. Oncogene (2023)
Niamh Coleman, Timothy Anthony Yap, John Victor Heymach, Funda Meric-Bernstam, Xiuning Li
Antibody-drug conjugates in lung cancer: dawn of a new era? NPJ precision oncology 7 (1) (2023)
Amber M Johnson, Patrick Kwok-Shing Ng, Michael Kahle, Julia Castillo, Bianca Amador, Yujia Wang, Jia Zeng, Vijaykumar Holla, Thuy Vu, Fei Su, Sun-Hee Kim, Tara Conway, Xianli Jiang, Ken Chen, Kenna R Mills Shaw, Timothy Anthony Yap, Jordi Rodon, Gordon B Mills, Funda Meric-Bernstam
Actionability classification of variants of unknown significance correlates with functional effect. NPJ precision oncology 7 (1) (2023)
Timothy Anthony Yap, Zsofia K Stadler, Leigh Anne Stout, Bryan P Schneider
Aligning Germline Cancer Predisposition With Tumor-Based Next-Generation Sequencing for Modern Oncology Diagnosis, Interception, and Therapeutic Development. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting 43 (2023)
Chuandong Geng, Man-Chao Zhang, Ganiraju C Manyam, Jody V Vykoukal, Johannes F Fahrmann, Shan Peng, Cheng Wu, Sanghee Park, Shakuntala Kondraganti, Daoqi Wang, Brian D Robinson, Massimo Loda, Christopher E Barbieri, Timothy Anthony Yap, Paul Gettys Corn, Samir M Hanash, Bradley M Broom, Patrick G Pilié, Timothy C Thompson
SPOP mutations target STING1 signaling in prostate cancer and create therapeutic vulnerabilities to PARP inhibitor-induced growth suppression. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Timothy Anthony Yap, Naval G Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Funda Meric-Bernstam, Hagop M Kantarjian, Farhad Ravandi, Meghan E Collins, Maria Emilia Di Francesco, Ecaterina E Dumbrava, Siqing Fu, Sisi Gao, Jason P Gay, Sonal Gera, Jing Han, David S Hong, Elias J Jabbour, Zhenlin Ju, Daniel D Karp, Alessia Lodi, Jennifer R Molina, Natalia Baran, Aung Naing, Maro Ohanian, Shubham Pant, Naveen Pemmaraju, Prithviraj Bose, Sarina A Piha-Paul, Jordi Rodon, Carolina Salguero, Koiji Sasaki, Anand K Singh, Vivek Subbiah, Apostolia M Tsimberidou, Quanyun A Xu, Musa Ylimaz, Qi Zhang, Yuan Li, Christopher A Bristow, Meenakshi B Bhattacharjee, Stefano Tiziani, Timothy P Heffernan, Christopher P Vellano, Philip Jones, Cobi J Heijnen, Annemieke Kavelaars, Joseph R Marszalek, Marina Y Konopleva
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials. Nature medicine (2023)
Xubin Li, Elisabeth K Dowling, Gonghong Yan, Zeynep Dereli, Behnaz Bozorgui, Parisa Imanirad, Jacob H Elnaggar, Augustin Luna, David G Menter, Patrick G Pilié, Timothy Anthony Yap, Scott Kopetz, Chris Sander, Anil Korkut
Precision Combination Therapies Based on Recurrent Oncogenic Coalterations. Cancer discovery 12 (6) (2022)
Justin Tyler Moyers, Roberto Carmagnani Pestana, Jason Roszik, David S Hong, Aung Naing, Siqing Fu, Sarina A Piha-Paul, Timothy Anthony Yap, Daniel D Karp, Jordi Rodon Ahnert, Jonathan A Livingston, Maria Alejandra Zarzour, Vinod Ravi, Shreyaskumar R Patel, Robert S Benjamin, Joseph A Ludwig, Cynthia E Herzog, Ravin Ratan, Neeta Somaiah, Anthony P Conley, Richard G Gorlick, Funda Meric-Bernstam, Vivek Subbiah
Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102). Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Tito R Mendoza, David S Hong, Christine B Peterson, Bettzy Stephen, Ecaterina Dumbrava, Shubbam Pant, Apostolia Maria Tsimberidou, Timothy Anthony Yap, Ajay Sheshadri, Mehmet Altan, Goldy George, Lilibeth Castillo, Enedelia Rodriguez, Jing Gong, Vivek Subbiah, Filip Janku, Siqing Fu, Sarina A Piha-Paul, Jordi Rodon Ahnert, Daniel D Karp, Charles Cleeland, Funda Meric-Bernstam, Aung Naing
Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial. Scientific reports 12 (1) (2022)
Timothy Anthony Yap, Justin F Gainor, Margaret K Callahan, Gerald S Falchook, Russell K Pachynski, Patricia LoRusso, Shivaani Kummar, Geoffrey T Gibney, Howard A Burris, Scott S Tykodi, Osama E Rahma, Tanguy Y Seiwert, Kyriakos P Papadopoulos, Mariela Blum Murphy, Haeseong Park, Amanda Hanson, Yasmin Hashambhoy-Ramsay, Lara McGrath, Ellen Hooper, Xiaoying Xiao, Heather Cohen, Martin Fan, Daniel Felitsky, Courtney Hart, Rachel McComb, Karen Brown, Ali Sepahi, Judith Jimenez, Weidong Zhang, Johan Baeck, Haley Laken, Richard Murray, Elizabeth Trehu, Christopher J Harvey
First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Timothy Anthony Yap, Erika Paige Hamilton, Todd M Bauer, Ecaterina E Ileana Dumbrava, Rinath Jeselsohn, Aaron Enke, Sabrina Hurley, Kevin K Lin, Jenn Habeck, Heidi Giordano, Geoffrey I Shapiro
Phase Ib SEASTAR Study: Combining Rucaparib and Sacituzumab Govitecan in Patients With Cancer With or Without Mutations in Homologous Recombination Repair Genes. JCO precision oncology 6 (2022)
Timothy Anthony Yap, Patricia M LoRusso, Deborah J Wong, Siwen Hu-Lieskovan, Kyriakos P Papadopoulos, Josefin-Beate Holz, Urszula Grabowska, Cristian Gradinaru, Kin-Mei Leung, Sylwia Marshall, Claire S Reader, Roslin Russell, Richard C A Sainson, Claire J Seal, Christopher J Shepherd, Fiona Germaschewski, Daniel R Gliddon, Omer Stern, Lesley Young, Neil Brewis, Louis Kayitalire, Michelle Morrow
A Phase 1 first-in-human study of FS118, a tetravalent bispecific antibody targeting LAG-3 and PD-L1 in patients with advanced cancer and PD-L1 resistance. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Aparna Hegde, Priyamvada Jayaprakash, Coline A Couillault, Sarina Piha-Paul, Daniel Karp, Jordi Rodon, Shubham Pant, Siqing Fu, Ecaterina E Dumbrava, Timothy Anthony Yap, Vivek Subbiah, Priya R Bhosale, Cristian Coarfa, Jack P Higgins, Eric T Williams, Thomas F Wilson, JoAnn Lim, Funda Meric-Bernstam, Elizabeth Sumner, Hira Zain, Di Nguyen, Ly M Nguyen, Kimal Rajapakshe, Michael A Curran, David S Hong
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (11) (2021)
Clinton Yam, Brigette Buig Yue Ma, Timothy Anthony Yap
Global Implementation of Precision Oncology. JCO precision oncology 5 (2021)
Kurt W Evans, Erkan Yuca, Stephen S Scott, Ming Zhao, Natalia Paez Arango, Christian X Cruz-Pico, Turcin Saridogan, Maryam Shariati, Caleb A Class, Christopher A Bristow, Christopher P Vellano, Xiaofeng Zheng, Ana Maria Gonzalez-Angulo, Xiaoping Su, Coya Tapia, Ken Chen, Argun Akcakanat, Bora Lim, Debasish Tripathy, Timothy Anthony Yap, Maria Emilia Di Francesco, Giulio F Draetta, Philip Jones, Timothy P Heffernan, Joseph R Marszalek, Funda Meric-Bernstam
Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer. Cancer research 81 (21) (2021)
Timothy Anthony Yap, Eileen E Parkes, Weiyi Peng, Justin Tyler Moyers, Michael A Curran, Hussein A Tawbi
Development of Immunotherapy Combination Strategies in Cancer. Cancer discovery 11 (6) (2021)
Geoffrey I Shapiro, Robert Wesolowski, Craig Devoe, Simon R Lord, John Pollard, Bart S Hendriks, Martin Falk, Ivan Diaz-Padilla, Ruth Plummer, Timothy Anthony Yap
Phase 1 study of the ATR inhibitor berzosertib in combination with cisplatin in patients with advanced solid tumours. British journal of cancer 125 (4) (2021)
Timothy Anthony Yap, Maria Vieito, Capucine Baldini, Juan Manuel Sepúlveda-Sánchez, Shunsuke Kondo, Matteo Simonelli, Rasha Cosman, Andre van der Westhuizen, Victoria Atkinson, Antoine F Carpentier, Mario Löhr, Rebecca Redman, Warren Mason, Andres Cervantes, Emilie Le Rhun, Sebastian Ochsenreither, Louise Warren, Yumin Zhao, Sophie Callies, Shawn T Estrem, Michael Man, Leena Gandhi, Emin Avsar, Davide Melisi
First-In-Human Phase I Study of a Next-Generation, Oral, TGFβ Receptor 1 Inhibitor, LY3200882, in Patients with Advanced Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Timothy Anthony Yap, Matthew G Krebs, Sophie Postel-Vinay, Anthony El-Khouiery, Jean-Charles Soria, Juanita Lopez, Alienor Berges, Sy Amy Cheung, Itziar Irurzun-Arana, Andrew Goldwin, Brunella Felicetti, Gemma N Jones, Alan Lau, Paul Frewer, Andrew J Pierce, Glen Clack, Christine Stephens, Simon A Smith, Emma Dean, Simon J Hollingsworth
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Zhe Tang, Patrick G Pilié, Chuandong Geng, Ganiraju C Manyam, Guang Yang, Sanghee Park, Daoqi Wang, Shan Peng, Cheng Wu, Guang Peng, Timothy Anthony Yap, Paul G Corn, Bradley M Broom, Timothy C Thompson
ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (17) (2021)
Virginia Giuliani, Meredith A Miller, Chiu-Yi Liu, Stella R Hartono, Caleb A Class, Christopher A Bristow, Erika Suzuki, Lionel A Sanz, Guang Gao, Jason P Gay, Ningping Feng, Johnathon L Rose, Hideo Tomihara, Joseph R Daniele, Michael D Peoples, Jennifer P Bardenhagen, Mary K Geck Do, Qing E Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K Deem, Kim-Anh Do, Giannicola Genovese, Joseph R Marszalek, Jeffrey J Kovacs, Michael Kim, Jason B Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M Emilia Di Francesco, Timothy Anthony Yap, Philip Jones, Giulio F Draetta, Alessandro Carugo, Frédéric Chedin, Timothy P Heffernan
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nature communications 12 (1) (2021)
Niamh Coleman, Bingnan Zhang, Lauren A Byers, Timothy Anthony Yap
The role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response. British journal of cancer 124 (5) (2020)
Gary M Middleton, Peter Fletcher, Sanjay Popat, Joshua S Savage, Yvonne Summers, Alastair Greystoke, David Gilligan, Judith Cave, Noelle O'Rourke, Alison Brewster, Elizabeth Toy, James Spicer, Pooja Jain, Adam Dangoor, Melanie Mackean, Martin Forster, Amanda Farley, Dee Wherton, Manita Mehmi, Rowena Sharpe, Tara C Mills, Maria Antonietta Cerone, Timothy Anthony Yap, Thomas B K Watkins, Emilia Lim, Charles Swanton, Lucinda Billingham
The National Lung Matrix Trial of personalized therapy in lung cancer. Nature 583 (7818) (2020)
Stephen J Pettitt, Jessica R Frankum, Marco Punta, Stefano Lise, John Alexander, Yi Chen, Timothy Anthony Yap, Syed Haider, Andrew N J Tutt, Christopher J Lord
Clinical BRCA1/2 Reversion Analysis Identifies Hotspot Mutations and Predicted Neoantigens Associated with Therapy Resistance. Cancer discovery 10 (10) (2020)
Timothy Anthony Yap, David Shao Peng Tan, Angelika Terbuch, Reece Caldwell, Christina Guo, Boon Cher Goh, Heong Valerie Yue Ming, Noor R Md Haris, Saira Bashir, Yvette Drew, David S Hong, Funda Meric-Bernstam, Gary Wilkinson, Joseph Hreiki, Antje M Wengner, Friedhelm Bladt, Andreas Schlicker, Matthias Ludwig, Yinghui Zhou, Li Liu, Sonal Bordia, Ruth Plummer, Eleni Lagkadinou, Johann S de Bono
First-in-Human Trial of the Oral Ataxia Telangiectasia and RAD3-Related (ATR) Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors. Cancer discovery 11 (1) (2020)
Javier Pascual, Joline S J Lim, Iain R J Macpherson, Anne C Armstrong, Alistair Ring, Alicia F C Okines, Rosalind J Cutts, Maria Teresa Herrera-Abreu, Isaac Garcia-Murillas, Alex Pearson, Sarah Hrebien, Heidrun Gevensleben, Paula Z Proszek, Michael Hubank, Margaret Hills, Jenny King, Mona Parmar, Toby Prout, Laura Finneran, Jason Malia, Karen E Swales, Ruth Ruddle, Florence I Raynaud, Alison Turner, Emma C Hall, Timothy Anthony Yap, Juanita S Lopez, Nicholas C Turner
Triplet Therapy with Palbociclib, Taselisib, and Fulvestrant in PIK3CA-Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers. Cancer discovery 11 (1) (2020)
Omar Alhalabi, Andrew W Hahn, Pavlos Msaouel, Alexander Y Andreev-Drakhlin, Funda Meric-Bernstam, Aung Naing, Sarina Piha-Paul, Filip Janku, Shubham Pant, Timothy Anthony Yap, David S Hong, Siqing Fu, Daniel Karp, Matthew T Campbell, Hung Le, Amishi Y Shah, Nizar M Tannir, Arlene O Siefker-Radtke, Jianjun Gao, Jason Roszik, Vivek Subbiah
Molecular Profiling of Metastatic Bladder Cancer Early-Phase Clinical Trial Participants Predicts Patient Outcomes. Molecular cancer research : MCR 19 (3) (2020)
Amita Patnaik, Timothy Anthony Yap, Hyun Cheol Chung, Maria J de Miguel Luken, Yung-Jue Bang, Chia-Chi Lin, Wu-Chou Su, Antoine Italiano, Kay Hoong Chow, Anna M Szpurka, Danni Yu, Yumin Zhao, Michelle Carlsen, Shelly Schmidt, Burkhard Vangerow, Leena Gandhi, Xiaojian Xu, Johanna Bendell
Safety and Clinical Activity of a New Anti-PD-L1 Antibody as Monotherapy or Combined with Targeted Therapy in Advanced Solid Tumors: The PACT Phase Ia/Ib Trial. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (5) (2020)
Timothy Anthony Yap, Rebecca S Kristeleit, Vasiliki Michalarea, Stephen J Pettitt, Joline S J Lim, Suzanne Carreira, Desamparados Roda, Rowan Miller, Ruth Riisnaes, Susana Miranda, Ines Figueiredo, Daniel Nava Rodrigues, Sarah Ward, Ruth Matthews, Mona Parmar, Alison Turner, Nina Tunariu, Neha Chopra, Heidrun Gevensleben, Nicholas C Turner, Ruth Ruddle, Florence I Raynaud, Shaun Decordova, Karen E Swales, Laura Finneran, Emma C Hall, Paul Rugman, Justin P O Lindemann, Andrew Foxley, Christopher J Lord, Udai Banerji, Ruth Plummer, Bristi Basu, Juanita S Lopez, Yvette Drew, Johann S de Bono
Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non-BRCA1/2-Mutant Cancers. Cancer discovery 10 (10) (2020)
Shubham Pant, Anirban Maitra, Timothy Anthony Yap
PARP inhibition - opportunities in pancreatic cancer. Nature reviews. Clinical oncology 16 (10) (2019)