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Chromosome-scale genome of the human blood fluke Schistosoma mekongi and its implications for public health.

Minyu ZhouLian XuDahua XuWen ChenJehangir KhanYue HuHui HuangHang WeiYiqing ZhangPhiraphol ChusongsangKanthi TanasarnprasertXiang HuYanin LimpanontZhiyue Lv
Published in: Infectious diseases of poverty (2023)
This study delivers a high-quality, chromosome-scale reference genome of S. mekongi, enhancing our understanding of the divergence and evolution of Schistosoma. The molecular research conducted here also plays a pivotal role in drug discovery and vaccine development. Furthermore, our work greatly advances the understanding of host-parasite interactions, providing crucial insights for schistosomiasis intervention strategies.
Keyphrases
  • drug discovery
  • public health
  • endothelial cells
  • randomized controlled trial
  • copy number
  • genome wide
  • induced pluripotent stem cells
  • pluripotent stem cells
  • toxoplasma gondii
  • global health