Genetic and environmental contributions to ancestry differences in gene expression in the human brain.

Kynon J M Benjamin Qiang Chen Nicholas J Eagles Louise A Huuki-Myers Leonardo Collado-TorresJoshua M StolzJoo Heon ShinApua C M Paquola Thomas M Hyde Joel E Kleinman Andrew E Jaffe Shizhong HanDaniel R Weinberger

Published in: bioRxiv : the preprint server for biology (2023)

We examine the impact of genetic ancestry on gene expression and DNA methylation of admixed African/Black Americans, highlighting how genetic and environmental background affect risk for brain illness.

Keyphrases

gene expression
dna methylation
genome wide
copy number
resting state
functional connectivity
risk assessment