Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system.
Mirjam RenovanzSylvia C KurzJohannes RiegerBianca WalterHannes BeckerHanni HillePaula BombachDavid RiegerLucia GrosseLara HäusserMarco SkardellyDaniel J MerkFrank PaulsenElgin HoffmannCihan GaniManuela NeumannRudi BeschornerOlaf RießCristiana RoggiaChristopher SchroederStephan OssowskiSorin Armeanu-EbingerAxel GschwindSaskia BiskupMartin SchulzeFalko FendStephan SingerLars ZenderClaudia LengerkeSara Yvonne BruckerTobias EnglerAndrea ForschnerArnulf StenzlOliver KohlbacherSven NahnsenGisela GabernetSven FillingerBenjamin BenderUlrike ErnemannÖznur ÖnerJanina BehaHolly Sundberg MalekYvonne MöllerKristina RuhmMarcos TatagibaCornelia BrendleMichael BitzerNisar MalekDaniel ZipsGhazaleh TabatabaiPublished in: Neuro-oncology advances (2023)
Our study supports the clinical utility of biomarker-guided therapies for neuro-oncology patients and indicates clinical benefit in a subset of patients. Our data might inform future clinical trials, translational studies, and even clinical care.