Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care: Protocol for the UK-ROX trial.

Daniel S MartinTasnin ShahidDoug William Gould Alvin Richards-BelleJames C DoidgeJulie CamsooksaiWalton N CharlesMiriam DaveyAmelia Francis JohnsonRoger M GarrettMichael Pw GrocottJoanne JonesLamprini LamproLorna MillerB Ronan O'DriscollAnthony J RostronZia SadiqueTamas SzakmanyPaul J YoungKathryn M RowanDavid A HarrisonPaul R Mouncey

Published in: Journal of the Intensive Care Society (2024)

The UK-ROX trial has received ethical approval from the South Central - Oxford C Research Ethics Committee (Reference: 20/SC/0423) and the Confidentiality Advisory Group (Reference: 22/CAG/0154). The trial commenced in May 2021 and, at the time of publication, 95 sites had opened to recruitment.

Keyphrases

phase iii
study protocol
phase ii
clinical trial
randomized controlled trial
public health
intensive care unit
cross sectional
machine learning
big data
global health
decision making